NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8) - Rat Genome Database

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Gene: NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8) Canis lupus familiaris
Analyze
Symbol: NDUFB8
Name: NADH:ubiquinone oxidoreductase subunit B8
RGD ID: 12157528
Description: INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (inferred); mitochondrial respiratory chain complex I assembly (inferred); ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); Arsenic Poisoning (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12813,249,067 - 13,253,670 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2813,249,070 - 13,253,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2813,420,026 - 13,424,630 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02813,718,281 - 13,722,885 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2813,717,817 - 13,722,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12813,264,760 - 13,269,366 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02813,306,376 - 13,310,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02813,437,377 - 13,441,981 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NDUFB8Dogacute kidney failure  ISORGD:13091299068941 RGDPMID:22160772|REF_RGD_ID:13801199
NDUFB8DogAlzheimer's disease  ISORGD:13192989068941 RGDPMID:14570706|REF_RGD_ID:1358651
NDUFB8DogKidney Reperfusion Injury  ISORGD:13091299068941 RGDPMID:24096033|REF_RGD_ID:13801197
NDUFB8DogKidney Reperfusion Injury  ISORGD:13192999068941 RGDPMID:22160772|REF_RGD_ID:13801199
NDUFB8DogParkinson's disease  ISORGD:13192989068941 RGDPMID:26605748|REF_RGD_ID:13504667
NDUFB8DogSepsis  ISORGD:13091299068941 RGDPMID:22952679|REF_RGD_ID:13801198
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NDUFB8Doggenetic disease  ISORGD:13192988554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868|PMID:28492532
NDUFB8Dognuclear type mitochondrial complex I deficiency 32  ISORGD:13192988554872ClinVar Annotator: match by term: MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 32 | ClinVar Annotator: more ...ClinVarPMID:25741868|PMID:28492532|PMID:29429571
NDUFB8Dogrenal coloboma syndrome  ISORGD:13192988554872ClinVar Annotator: match by term: Renal coloboma syndromeClinVarPMID:11461952|PMID:24676634|PMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NDUFB8DogArsenic Poisoning  ISORGD:13192989068941CTD Direct Evidence: marker/mechanismCTDPMID:16835338
NDUFB8Dogskin disease  ISORGD:13192989068941CTD Direct Evidence: marker/mechanismCTDPMID:16835338
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NDUFB8Dognuclear type mitochondrial complex I deficiency 32  ISORGD:13192987240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NDUFB8Dogmitochondrial electron transport, NADH to ubiquinone involved_inIEAInterPro:IPR016551150520179 InterProGO_REF:0000002
NDUFB8Dogmitochondrial electron transport, NADH to ubiquinone involved_inIEAUniRule:UR000168457150520179 UniProtGO_REF:0000104
NDUFB8Dogmitochondrial respiratory chain complex I assembly involved_inIEAUniRule:UR000168457150520179 UniProtGO_REF:0000104

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NDUFB8Dogmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
NDUFB8Dogmitochondrial inner membrane located_inIEAUniProtKB-SubCell:SL-0168150520179 UniProtGO_REF:0000044
NDUFB8Dogmitochondrial inner membrane is_active_inIEAUniProtKB:Q9D6J5|ensembl:ENSMUSP00000026222150520179 EnsemblGO_REF:0000107
NDUFB8Dogmitochondrial inner membrane located_inIEAUniProtKB:O95169|ensembl:ENSP00000299166150520179 EnsemblGO_REF:0000107
NDUFB8Dogmitochondrial inner membrane located_inIEAUniProtKB-KW:KW-0999150520179 UniProtGO_REF:0000043
NDUFB8Dogmitochondrion located_inIEAUniProtKB-KW:KW-0496150520179 UniProtGO_REF:0000043
NDUFB8Dogmitochondrion located_inIEAInterPro:IPR008699150520179 InterProGO_REF:0000002
NDUFB8Dogmitochondrion located_inIEAUniProtKB:O95169|UniProtKB:Q9D6J5|ensembl:ENSMUSP00000026222|ensembl:ENSP00000299166150520179 EnsemblGO_REF:0000107
NDUFB8Dogrespiratory chain complex I part_ofIEAUniProtKB:O95169|UniProtKB:Q9D6J5|ensembl:ENSMUSP00000026222|ensembl:ENSP00000299166150520179 EnsemblGO_REF:0000107
NDUFB8Dogrespiratory chain complex I part_ofIEAUniRule:UR000168457150520179 UniProtGO_REF:0000104
NDUFB8Dogrespiratory chain complex I part_ofIBAFB:FBgn0029888|MGI:1914514|PANTHER:PTN001401346|UniProtKB:O95169|UniProtKB:Q02372150520179 GO_CentralGO_REF:0000033
1 to 11 of 11 rows

PMID:22301074   PMID:30032202  



NDUFB8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12813,249,067 - 13,253,670 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2813,249,070 - 13,253,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2813,420,026 - 13,424,630 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02813,718,281 - 13,722,885 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2813,717,817 - 13,722,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12813,264,760 - 13,269,366 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02813,306,376 - 13,310,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02813,437,377 - 13,441,981 (-)NCBIUU_Cfam_GSD_1.0
NDUFB8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810100,523,729 - 100,529,923 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10100,523,668 - 100,530,000 (-)EnsemblGRCh38hg38GRCh38
GRCh3710102,283,486 - 102,289,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610102,273,487 - 102,279,626 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410102,273,486 - 102,279,626NCBI
Celera1096,021,344 - 96,027,467 (-)NCBICelera
Cytogenetic Map10q24.31NCBI
HuRef1095,912,314 - 95,918,432 (-)NCBIHuRef
CHM1_110102,568,149 - 102,574,284 (-)NCBICHM1_1
T2T-CHM13v2.010101,406,832 - 101,413,008 (-)NCBIT2T-CHM13v2.0
Ndufb8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,537,010 - 44,543,881 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1944,537,011 - 44,543,879 (-)EnsemblGRCm39 Ensembl
GRCm381944,548,571 - 44,555,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,548,572 - 44,555,440 (-)EnsemblGRCm38mm10GRCm38
MGSCv371944,624,744 - 44,629,905 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361944,603,565 - 44,608,726 (-)NCBIMGSCv36mm8
Celera1945,317,871 - 45,323,032 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1937.98NCBI
Ndufb8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81253,357,878 - 253,362,936 (-)NCBIGRCr8
mRatBN7.21243,408,656 - 243,413,715 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,408,619 - 243,413,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1251,553,580 - 251,558,636 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01258,254,776 - 258,259,815 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,903,779 - 250,908,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01264,298,671 - 264,303,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1264,298,669 - 264,303,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,741,836 - 271,746,877 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,597,402 - 249,602,443 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11249,857,515 - 249,862,713 (-)NCBI
Celera1239,222,776 - 239,227,817 (-)NCBICelera
Cytogenetic Map1q54NCBI
Ndufb8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554859,607,781 - 9,613,151 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554859,607,781 - 9,613,123 (+)NCBIChiLan1.0ChiLan1.0
NDUFB8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,407,560 - 112,419,817 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,412,880 - 112,425,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01097,123,826 - 97,129,919 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110100,604,914 - 100,611,016 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10100,604,914 - 100,611,016 (-)Ensemblpanpan1.1panPan2
Ndufb8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721333,518,864 - 33,523,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366005,116,423 - 5,129,334 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366005,122,004 - 5,126,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFB8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14111,626,097 - 111,633,564 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114111,626,827 - 111,633,548 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2463,909,851 - 63,916,428 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFB8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,544,663 - 93,550,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl993,544,589 - 93,550,905 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604854,592,819 - 54,598,911 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufb8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624831191,625 - 200,860 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624831195,552 - 200,458 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in NDUFB8
29 total Variants



adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10



Ensembl Acc Id: ENSCAFT00000037266   ⟹   ENSCAFP00000032744
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2813,249,070 - 13,253,595 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000084120   ⟹   ENSCAFP00000044305
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2813,249,415 - 13,253,619 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845031997   ⟹   ENSCAFP00845025022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2813,717,817 - 13,722,828 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845032039   ⟹   ENSCAFP00845025052
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2813,718,629 - 13,722,833 (-)Ensembl
RefSeq Acc Id: XM_005637621   ⟹   XP_005637678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12813,249,067 - 13,253,670 (-)NCBI
Dog10K_Boxer_Tasha2813,420,026 - 13,424,630 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038440301   ⟹   XP_038296229
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02813,718,281 - 13,722,885 (-)NCBI
RefSeq Acc Id: XM_038514918   ⟹   XP_038370846
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12813,264,760 - 13,269,366 (-)NCBI
RefSeq Acc Id: XM_038578532   ⟹   XP_038434460
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02813,437,377 - 13,441,981 (-)NCBI
RefSeq Acc Id: XM_038642714   ⟹   XP_038498642
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02813,306,376 - 13,310,981 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs XP_005637678 (Get FASTA)   NCBI Sequence Viewer  
  XP_038296229 (Get FASTA)   NCBI Sequence Viewer  
  XP_038370846 (Get FASTA)   NCBI Sequence Viewer  
  XP_038434460 (Get FASTA)   NCBI Sequence Viewer  
  XP_038498642 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000032744.4
  ENSCAFP00000044305.1
  ENSCAFP00845025022
  ENSCAFP00845025022.1
  ENSCAFP00845025052.1
1 to 10 of 10 rows
RefSeq Acc Id: XP_005637678   ⟸   XM_005637621
- UniProtKB: A0A8C0QXG7 (UniProtKB/TrEMBL),   A0A8I3NUH5 (UniProtKB/TrEMBL),   A0A8P0SPY6 (UniProtKB/TrEMBL),   A0A8I3P543 (UniProtKB/TrEMBL),   A0A8P0NUR7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000044305   ⟸   ENSCAFT00000084120
Ensembl Acc Id: ENSCAFP00000032744   ⟸   ENSCAFT00000037266
RefSeq Acc Id: XP_038370846   ⟸   XM_038514918
RefSeq Acc Id: XP_038498642   ⟸   XM_038642714



1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000009698 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845018078 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000037266.4 UniProtKB/TrEMBL
  ENSCAFT00000084120.2 UniProtKB/TrEMBL
  ENSCAFT00845031997 ENTREZGENE
  ENSCAFT00845031997.1 UniProtKB/TrEMBL
  ENSCAFT00845032039.1 UniProtKB/TrEMBL
InterPro NDUFB8 UniProtKB/TrEMBL
  Ndufb8_metazoa UniProtKB/TrEMBL
KEGG Report cfa:477798 UniProtKB/TrEMBL
NCBI Gene NDUFB8 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12840 UniProtKB/TrEMBL
Pfam NDUF_B8 UniProtKB/TrEMBL
PIRSF NDUB8 UniProtKB/TrEMBL
UniProt A0A8C0QXG7 ENTREZGENE
  A0A8I3NUH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P543 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NUR7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SPY6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:53001 ENTREZGENE
1 to 21 of 21 rows