Hic1 (HIC ZBTB transcriptional repressor 1) - Rat Genome Database

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Gene: Hic1 (HIC ZBTB transcriptional repressor 1) Rattus norvegicus
Analyze
Symbol: Hic1
Name: HIC ZBTB transcriptional repressor 1
RGD ID: 1307527
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and sequence-specific double-stranded DNA binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of transcription by RNA polymerase II; and regulation of signal transduction. Predicted to be located in chromatin. Predicted to be active in nucleus. Orthologous to human HIC1 (HIC ZBTB transcriptional repressor 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypermethylated in cancer 1; hypermethylated in cancer 1 protein; hypermethylated in cancer 1 protein-like; LOC100912068; LOC303310
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,512,855 - 60,517,812 (-)NCBIGRCr8
mRatBN7.21060,014,520 - 60,019,475 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,011,528 - 60,019,475 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,661,147 - 64,666,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,166,728 - 64,171,679 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,629,108 - 59,634,061 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,007,150 - 62,010,774 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,007,150 - 62,009,582 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,721,540 - 61,725,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,470,736 - 62,476,506 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11062,485,182 - 62,492,086 (-)NCBI
Celera1059,044,464 - 59,049,428 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hic1RatBreast Neoplasms  ISOHIC1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20154726
Hic1RatGastrointestinal Neoplasms  ISOHIC1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21297660
Hic1Ratmacular degeneration  ISOHIC1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:30742112
Hic1Ratmedulloblastoma  ISOHIC1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18347096
Hic1RatPolyps  ISOHIC1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21297660
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hic1RatMiller-Dieker lissencephaly syndrome  ISSHic1 (Mus musculus)13592920OMIM:247200MouseDO 

1 to 20 of 101 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hic1Rat(-)-demecolcine decreases expressionISOHIC1 (Homo sapiens)6480464Demecolcine results in decreased expression of HIC1 mRNACTDPMID:23649840
Hic1Rat1,2-dichloroethane decreases expressionISOHic1 (Mus musculus)6480464ethylene dichloride results in decreased expression of HIC1 mRNACTDPMID:28960355
Hic1Rat1,2-dimethylhydrazine multiple interactionsISOHic1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HIC1 mRNACTDPMID:22206623
Hic1Rat17beta-estradiol multiple interactionsISOHIC1 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of HIC1 mRNACTDPMID:30165855
Hic1Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642 more ...CTDPMID:27291303
Hic1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOHic1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of HIC1 mRNACTDPMID:19933214
Hic1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of HIC1 mRNACTDPMID:33387578
Hic1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of HIC1 mRNACTDPMID:27913140
Hic1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOHIC1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of HIC1 mRNACTDPMID:27913140
Hic1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of HIC1 mRNACTDPMID:22298810
Hic1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOHic1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of HIC1 mRNACTDPMID:20159946 and PMID:27913140
Hic1Rat3,3',4,4',5-pentachlorobiphenyl increases expressionEXP 64804643 more ...CTDPMID:32119087
Hic1Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOHIC1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of HIC1 mRNACTDPMID:28628672
Hic1Rat4,4'-sulfonyldiphenol increases expressionISOHic1 (Mus musculus)6480464bisphenol S results in increased expression of HIC1 mRNACTDPMID:30951980
Hic1Rat4,4'-sulfonyldiphenol affects methylationISOHic1 (Mus musculus)6480464bisphenol S affects the methylation of HIC1 geneCTDPMID:31683443
Hic1Rat4,4'-sulfonyldiphenol increases methylationISOHIC1 (Homo sapiens)6480464bisphenol S results in increased methylation of HIC1 geneCTDPMID:31601247
Hic1Rat4,4'-sulfonyldiphenol multiple interactionsISOHic1 (Mus musculus)6480464[bisphenol S co-treated with Tretinoin] results in decreased expression of HIC1 mRNACTDPMID:30951980
Hic1Rat5-aza-2'-deoxycytidine increases expressionISOHIC1 (Homo sapiens)6480464Decitabine results in increased expression of HIC1 mRNACTDPMID:19440673
Hic1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of HIC1 mRNACTDPMID:24780913
Hic1Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of HIC1 mRNACTDPMID:28959563

1 to 20 of 101 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hic1Ratchromatin located_inISOHic1 (Mus musculus)1624291 PMID:16269335RGDPMID:16269335
Hic1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Hic1Ratnucleus is_active_inIBAFB:FBgn0000283 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Hic1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12052894   PMID:15231840   PMID:16269335   PMID:16724116  



Hic1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,512,855 - 60,517,812 (-)NCBIGRCr8
mRatBN7.21060,014,520 - 60,019,475 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,011,528 - 60,019,475 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,661,147 - 64,666,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,166,728 - 64,171,679 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,629,108 - 59,634,061 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,007,150 - 62,010,774 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,007,150 - 62,009,582 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,721,540 - 61,725,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,470,736 - 62,476,506 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11062,485,182 - 62,492,086 (-)NCBI
Celera1059,044,464 - 59,049,428 (-)NCBICelera
Cytogenetic Map10q24NCBI
HIC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38172,055,103 - 2,063,241 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl172,054,154 - 2,063,241 (+)EnsemblGRCh38hg38GRCh38
GRCh37171,958,397 - 1,966,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,905,143 - 1,909,731 (+)NCBINCBI36Build 36hg18NCBI36
Build 34171,906,714 - 1,908,879NCBI
Celera171,974,408 - 1,978,996 (+)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef171,853,855 - 1,857,995 (+)NCBIHuRef
CHM1_1171,967,163 - 1,971,751 (+)NCBICHM1_1
T2T-CHM13v2.0171,942,378 - 1,950,518 (+)NCBIT2T-CHM13v2.0
Hic1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,052,203 - 75,059,970 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,055,391 - 75,060,345 (-)EnsemblGRCm39 Ensembl
GRCm381175,161,377 - 75,170,255 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,164,565 - 75,169,519 (-)EnsemblGRCm38mm10GRCm38
MGSCv371174,978,067 - 74,983,757 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,980,763 - 74,985,714 (-)NCBIMGSCv36mm8
Celera1182,671,336 - 82,677,017 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
Hic1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,179,015 - 1,181,825 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,179,015 - 1,182,936 (-)NCBIChiLan1.0ChiLan1.0
HIC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,635,373 - 9,640,053 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,602,754 - 11,607,442 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0172,045,960 - 2,051,483 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,935,628 - 1,937,474 (+)NCBIpanpan1.1PanPan1.1panPan2
HIC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1946,156,909 - 46,162,849 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl946,159,136 - 46,162,004 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,306,957 - 45,312,945 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,987,712 - 46,993,723 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,989,156 - 46,993,692 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1945,754,761 - 45,760,755 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,049,100 - 46,055,081 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0946,104,136 - 46,110,131 (+)NCBIUU_Cfam_GSD_1.0
Hic1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560245,241,606 - 45,248,219 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365388,122,749 - 8,125,306 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365388,122,557 - 8,126,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,168,900 - 48,172,636 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11248,167,861 - 48,172,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21250,021,109 - 50,025,558 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,687,560 - 1,697,888 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,694,341 - 1,697,023 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605920,267,675 - 20,271,313 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hic1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247864,724,806 - 4,729,714 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Hic1
16 total Variants

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:106
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000004143, ENSRNOT00000066972
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 78 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104698969968663659Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat

1 to 10 of 78 rows
Hic1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8337,395,772 - 37,396,092 (+)Marker Load Pipeline
Rnor_6.01062,007,652 - 62,007,753NCBIRnor6.0
Rnor_5.01061,722,042 - 61,722,143UniSTSRnor5.0
RGSC_v3.41062,471,238 - 62,471,338UniSTSRGSC3.4
Celera1059,044,969 - 59,045,066UniSTS
Cytogenetic Map10q24UniSTS
BE100929  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21060,019,266 - 60,019,416 (+)MAPPERmRatBN7.2
Rnor_6.01062,010,566 - 62,010,715NCBIRnor6.0
Rnor_5.01061,724,956 - 61,725,105UniSTSRnor5.0
RGSC_v3.41062,476,298 - 62,476,447UniSTSRGSC3.4
Celera1059,049,220 - 59,049,369UniSTS
Cytogenetic Map10q24UniSTS
G54872  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21060,015,541 - 60,015,789 (+)MAPPERmRatBN7.2
Rnor_6.01062,480,957 - 62,481,204NCBIRnor6.0
Rnor_6.01062,008,171 - 62,008,418NCBIRnor6.0
Rnor_5.01061,722,561 - 61,722,808UniSTSRnor5.0
Rnor_5.01062,192,273 - 62,192,520UniSTSRnor5.0
RGSC_v3.41062,471,756 - 62,472,003UniSTSRGSC3.4
Celera1059,045,484 - 59,045,731UniSTS
Cytogenetic Map10q24UniSTS
RH124699  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21060,014,518 - 60,014,663 (+)MAPPERmRatBN7.2
Rnor_6.01062,007,149 - 62,007,293NCBIRnor6.0
Rnor_5.01061,721,539 - 61,721,683UniSTSRnor5.0
RGSC_v3.41062,470,735 - 62,470,879UniSTSRGSC3.4
Celera1059,044,466 - 59,044,610UniSTS
Cytogenetic Map10q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000004143   ⟹   ENSRNOP00000004143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1060,014,507 - 60,018,109 (-)Ensembl
Rnor_6.0 Ensembl1062,007,150 - 62,009,582 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079956   ⟹   ENSRNOP00000074161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1060,014,520 - 60,019,475 (-)Ensembl
Rnor_6.0 Ensembl1062,480,767 - 62,483,342 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115646   ⟹   ENSRNOP00000090248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1060,011,528 - 60,019,160 (-)Ensembl
RefSeq Acc Id: NM_001107021   ⟹   NP_001100491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,512,858 - 60,517,812 (-)NCBI
mRatBN7.21060,014,520 - 60,019,475 (-)NCBI
Rnor_6.01062,007,150 - 62,010,774 (-)NCBI
Rnor_5.01061,721,540 - 61,725,164 (-)NCBI
RGSC_v3.41062,470,736 - 62,476,506 (-)RGD
Sequence:
RefSeq Acc Id: NM_001422893   ⟹   NP_001409822
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,512,855 - 60,517,445 (-)NCBI
RefSeq Acc Id: XM_063269069   ⟹   XP_063125139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,512,855 - 60,516,453 (-)NCBI
RefSeq Acc Id: XM_063269070   ⟹   XP_063125140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81060,512,855 - 60,517,030 (-)NCBI
RefSeq Acc Id: NP_001100491   ⟸   NM_001107021
- Peptide Label: isoform 2
- Sequence:
Ensembl Acc Id: ENSRNOP00000004143   ⟸   ENSRNOT00000004143
Ensembl Acc Id: ENSRNOP00000074161   ⟸   ENSRNOT00000079956
Ensembl Acc Id: ENSRNOP00000090248   ⟸   ENSRNOT00000115646
RefSeq Acc Id: NP_001409822   ⟸   NM_001422893
- Peptide Label: isoform 1
- UniProtKB: A0A8I6ADF2 (UniProtKB/TrEMBL),   A0A0G2K7D6 (UniProtKB/TrEMBL),   A6HGP3 (UniProtKB/TrEMBL)
BTB   C2H2-type

Name Modeler Protein Id AA Range Protein Structure
AF-D4A974-F1-model_v2 AlphaFold D4A974 1-535 view protein structure
AF-A0A0G2K7D6-F1-model_v2 AlphaFold A0A0G2K7D6 1-740 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 35 of 35 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-24234 BioCyc
Ensembl Genes ENSRNOG00000046405 Ensembl
  ENSRNOG00000057619 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004143.5 UniProtKB/TrEMBL
  ENSRNOT00000079956.2 UniProtKB/TrEMBL
  ENSRNOT00000115646 ENTREZGENE
  ENSRNOT00000115646.1 UniProtKB/TrEMBL
  ENSRNOT00000162854 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
NCBI Gene 303310 ENTREZGENE
PANTHER HYPERMETHYLATED IN CANCER 1 PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Hic1 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046405 RatGTEx
  ENSRNOG00000057619 RatGTEx
SMART BTB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2K7D6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADF2 ENTREZGENE, UniProtKB/TrEMBL
  A6HGP3 ENTREZGENE, UniProtKB/TrEMBL
  D4A974 ENTREZGENE, UniProtKB/TrEMBL
  E5D4G5_RAT UniProtKB/TrEMBL
  E5D4G6_RAT UniProtKB/TrEMBL
1 to 35 of 35 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hic1  HIC ZBTB transcriptional repressor 1  LOC100912068  hypermethylated in cancer 1 protein-like  Data merged from RGD:6488990 737654 PROVISIONAL
2016-10-12 Hic1  HIC ZBTB transcriptional repressor 1  Hic1  hypermethylated in cancer 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100912068  hypermethylated in cancer 1 protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Hic1  hypermethylated in cancer 1   Hic1_predicted  hypermethylated in cancer 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Hic1_predicted  hypermethylated in cancer 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED