Hic1 (HIC ZBTB transcriptional repressor 1)

Gene: Hic1 (HIC ZBTB transcriptional repressor 1) Chinchilla lanigera

Analyze

Symbol:

Hic1

Name:

HIC ZBTB transcriptional repressor 1

RGD ID:

8908971

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); histone deacetylase binding (ortholog); INVOLVED IN intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of Wnt signaling pathway (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Gastrointestinal Neoplasms (ortholog); genetic disease (ortholog); FOUND IN chromatin (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hypermethylated in cancer 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	1,179,015 - 1,181,825 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	1,179,015 - 1,182,936 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Neoplasms (ISO)

Gastrointestinal Neoplasms (ISO)

genetic disease (ISO)

macular degeneration (ISO)

medulloblastoma (ISO)

Miller-Dieker lissencephaly syndrome (ISO)

Polyps (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intrinsic apoptotic signaling pathway in response to DNA damage (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

negative regulation of Wnt signaling pathway (ISO)

positive regulation of DNA damage response, signal transduction by p53 class mediator (ISO)

Cellular Component

chromatin (ISO)

Molecular Function

DNA-binding transcription factor activity (ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

histone deacetylase binding (ISO)

protein binding (ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hic1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	1,179,015 - 1,181,825 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	1,179,015 - 1,182,936 (-)	NCBI	ChiLan1.0	ChiLan1.0

HIC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	2,055,103 - 2,063,241 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	2,054,154 - 2,063,241 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	1,958,397 - 1,966,535 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	1,905,143 - 1,909,731 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	1,906,714 - 1,908,879	NCBI
Celera	17	1,974,408 - 1,978,996 (+)	NCBI		Celera
Cytogenetic Map	17	p13.3	NCBI
HuRef	17	1,853,855 - 1,857,995 (+)	NCBI		HuRef
CHM1_1	17	1,967,163 - 1,971,751 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	1,942,378 - 1,950,518 (+)	NCBI		T2T-CHM13v2.0

Hic1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	75,052,203 - 75,059,970 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	75,055,391 - 75,060,345 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	75,161,377 - 75,170,255 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	75,164,565 - 75,169,519 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	74,978,067 - 74,983,757 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	74,980,763 - 74,985,714 (-)	NCBI		MGSCv36	mm8
Celera	11	82,671,336 - 82,677,017 (-)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	45.76	NCBI

Hic1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	60,512,855 - 60,517,812 (-)	NCBI		GRCr8
mRatBN7.2	10	60,014,520 - 60,019,475 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	60,011,528 - 60,019,475 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	64,661,147 - 64,666,097 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	64,166,728 - 64,171,679 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	59,629,108 - 59,634,061 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	62,007,150 - 62,010,774 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	62,007,150 - 62,009,582 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	61,721,540 - 61,725,164 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	62,470,736 - 62,476,506 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	62,485,182 - 62,492,086 (-)	NCBI
Celera	10	59,044,464 - 59,049,428 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

HIC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	9,635,373 - 9,640,053 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	11,602,754 - 11,607,442 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	2,045,960 - 2,051,483 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	1,935,628 - 1,937,474 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

HIC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	46,156,909 - 46,162,849 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	46,159,136 - 46,162,004 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	45,306,957 - 45,312,945 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	46,987,712 - 46,993,723 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	46,989,156 - 46,993,692 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	45,754,761 - 45,760,755 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	46,049,100 - 46,055,081 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	46,104,136 - 46,110,131 (+)	NCBI		UU_Cfam_GSD_1.0

Hic1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	45,241,606 - 45,248,219 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	8,122,749 - 8,125,306 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	8,122,557 - 8,126,157 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HIC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	48,168,900 - 48,172,636 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	48,167,861 - 48,172,540 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	50,021,109 - 50,025,558 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HIC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	1,687,560 - 1,697,888 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	1,694,341 - 1,697,023 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	20,267,675 - 20,271,313 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hic1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624786	4,724,806 - 4,729,714 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005402595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005402596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005402597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01056827	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01056828	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01208306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000011845 ⟹ ENSCLAP00000011707

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955481	1,179,015 - 1,181,825 (-)	Ensembl

RefSeq Acc Id:

XM_005402595 ⟹ XP_005402652

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	1,179,015 - 1,181,825 (-)	NCBI

Sequence:

show sequence

CCGGCCTTCGTTCTCTGCCCGCCACGGCAGCCGCTGCCTCTGCTCCGGCGCCGCTGCCCTACCC
CAAACAAGGGTGTGACAGCCCCCCGCCAGGGCTGCGCCGCAGTGGGCACCTCGCCCCCGTCCTC
CGAATCACTTCCCCCAACTGGGGCAACTTCTCCCGAGGCGGGAGGCGCTTCTTACTCGGCTCCT
TTTCTACCCACTTGGGCAAACTTCTTGGCCCTGAATGACTTTTCCTGAAGCGGACATTTTACTT
AAATCGGGAGAGTGTGCTGGGCAGACGATGCTGGACACGATGGAGGCGCCCGGCCACTCGAGGC
AGCTGCTGCTGCAGCTCAACAACCAGCGCACCAAGGGCTTCTTGTGCGACGTGATCATCGTGGT
GCAAAACGCCCTCTTCCGCGCGCACAAGAACGTGCTGGCGGCCAGCAGTGCCTACCTCAAGTCC
CTGGTGGTGCATGACAACCTGCTCAACCTGGACCATGACATGGTGAGCCCGGCCGTGTTCCGCC
TGGTGCTGGACTTCATCTACACCGGCCGTCTGGCTGACGGTGCAGAGGCAGCTGCAGCGGCGGC
CGTGGCCCCAGGGGCCGAGCCGAGCCTGGGTGCGGTGCTGGCCGCAGCCAGCTACCTGCAGATC
CCTGACCTCGTGGCGCTGTGCAAGAAGCGCCTCAAGCGCCACGGCAAGTACTGTCACCTGAGGG
GAGGTGGCAGCGGTGGCGGCGGTTATGCGCCCTACGGGAGGCCGGGCCGTGGCCTGAGGGCCGC
CACGCCCGTCATTCAGACCTGCTACTCGTCTCCAGCCGGGCCCCCGCCACCGCCCACCTCCGAG
CCGCCGTCGGGCCCCGAGGCCTCGGTCAACACGCACTGTGCAGAGCTGTACGCCTCGGGGCCCG
GCCCCGCCGCCGCGCTGTGCGCCCCAGAGCGCCGCTGCTCTCCGCTCTGCGGCCTGGACCTATC
CAAGAAGAGCCCGCCCGGCTCTGCGGTTCCCGAGCGGCCCCTGAGTGAGCGCGACCTGCCCCCG
CGGCCCGACAGCCCTCCCAGCGCGGGCCCCGCCGCCTACAAGGAGCCCCCGCTCGCCCTGCCGC
CGCTGCCGCCGCTGCCCTTCCAAAAGCTGGAGGAGGCCGCGCCCCCGCCGGACCCGTTTCGCGG
CAGCGGCGGCAGCCCGGGACCCGAGCCCCCCGGCCGCCCCGACGGGCCCAGCCTCCTCTACCGC
TGGATGAAGCACGAGCCGGGGCTGAGCAGCTACGGGGACGAGCTGAGCCGGGAGCGCGGCTCCC
CCGGCGAGCGCTGCGAGGAGCGCGGGGGAGACCCGGCCGTCTCGCCTGGGGGGCCCCCGCTGGG
CCTGGGGCCGCCGCCGCGCTACCCCGGCAGCCTGGACGGGCCCGGCGCGGGCGGCGACGGCGAC
GACTACAAGAGCAGCAGCGAGGAGACGGGCAGCAGCGAGGACCCCAGCCCTCCCGGCGGCCACC
TGGAGGGCTACCCCTGCCCGCACCTGGCTTACGGCGAGCCGGAGAGCTTCGGGGACAACTTATA
CGTGTGCATCCCGTGCGGCAAGGGCTTCCCCAGCTCCGAGCAGCTGAACGCGCACGTGGAGGCT
CACGTAGAGGAGGAGGAGGCGCTGTACGGCAGGGCCGAGGCGGCTGAGGTGGCGGCCGGGCCCC
CTTTTGGGAGCGGTGCGGACAAGGTCGCTGGGGCTCCGGGCAGCCTAGGAGAGCTGCTGCGGCC
ATACCGCTGCGCGTCCTGCGACAAGAGCTACAAGGACCCGGCCACGCTGCGGCAGCACGAGAAG
ACGCACTGGCTGACCCGGCCTTATCCATGCACCATATGCGGGAAGAAGTTCACGCAACGCGGGA
CCATGACGCGCCACATGCGCAGCCACCTGGGCCTCAAGCCCTTTGCGTGCGACGCGTGCGGCAT
GCGCTTCACGCGCCAGTACCGCCTCACGGAGCACATGCGCATCCACTCGGGCGAGAAGCCCTAC
GAGTGCCAAGTGTGCGGCGGCAAGTTCGCACAGCAACGCAACCTCATCAGCCACATGAAGATGC
ACGCCGTGGGCGGCGCGGCCGGCGCGGCCGGGGCGCTGGCAGGTCTAGGGGGCCTACCCGGCGT
CCCCGGCCCCGACGGCAAAGGCAAGCTTGACTTCCCCGAGGGCGTCTTTGCTGTGGCCCGCCTC
ACGGCGGAACAGCTGAGCCTGAAGCAGCAGGACAAGGCGGCTGCGGCCGAGCTGCTGGCGCAGA
CCACGCACTTCCTGCACGACCCCAAGGTGGCGCTCGAGAGCCTCTACCCGCTGGCCAAGTTCAC
GGCGGAGCTGGGCCTCAGCCCAGACAAGGCGGCGGAGGTGCTGAGCCAGGGCGCTCACCTGGCC
GCGGGTCCCGACGGCCGGACCATCGACCGTTTCTCTCCCACCTAGAGCACCTCTCGCCGGCCCT
CCTTGCCGCCGCCCCGCGCGCGGCCCGGCCC

hide sequence

RefSeq Acc Id:

XM_005402596 ⟹ XP_005402653

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	1,179,015 - 1,182,439 (-)	NCBI

Sequence:

show sequence

GCGCGGGCTAGGAGCTGCCACTGCCGCGGGGAGGGAAGCCCGGCAGGGCTGCGGCTGCAGGAGA
GTGTGCTGGGCAGACGATGCTGGACACGATGGAGGCGCCCGGCCACTCGAGGCAGCTGCTGCTG
CAGCTCAACAACCAGCGCACCAAGGGCTTCTTGTGCGACGTGATCATCGTGGTGCAAAACGCCC
TCTTCCGCGCGCACAAGAACGTGCTGGCGGCCAGCAGTGCCTACCTCAAGTCCCTGGTGGTGCA
TGACAACCTGCTCAACCTGGACCATGACATGGTGAGCCCGGCCGTGTTCCGCCTGGTGCTGGAC
TTCATCTACACCGGCCGTCTGGCTGACGGTGCAGAGGCAGCTGCAGCGGCGGCCGTGGCCCCAG
GGGCCGAGCCGAGCCTGGGTGCGGTGCTGGCCGCAGCCAGCTACCTGCAGATCCCTGACCTCGT
GGCGCTGTGCAAGAAGCGCCTCAAGCGCCACGGCAAGTACTGTCACCTGAGGGGAGGTGGCAGC
GGTGGCGGCGGTTATGCGCCCTACGGGAGGCCGGGCCGTGGCCTGAGGGCCGCCACGCCCGTCA
TTCAGACCTGCTACTCGTCTCCAGCCGGGCCCCCGCCACCGCCCACCTCCGAGCCGCCGTCGGG
CCCCGAGGCCTCGGTCAACACGCACTGTGCAGAGCTGTACGCCTCGGGGCCCGGCCCCGCCGCC
GCGCTGTGCGCCCCAGAGCGCCGCTGCTCTCCGCTCTGCGGCCTGGACCTATCCAAGAAGAGCC
CGCCCGGCTCTGCGGTTCCCGAGCGGCCCCTGAGTGAGCGCGACCTGCCCCCGCGGCCCGACAG
CCCTCCCAGCGCGGGCCCCGCCGCCTACAAGGAGCCCCCGCTCGCCCTGCCGCCGCTGCCGCCG
CTGCCCTTCCAAAAGCTGGAGGAGGCCGCGCCCCCGCCGGACCCGTTTCGCGGCAGCGGCGGCA
GCCCGGGACCCGAGCCCCCCGGCCGCCCCGACGGGCCCAGCCTCCTCTACCGCTGGATGAAGCA
CGAGCCGGGGCTGAGCAGCTACGGGGACGAGCTGAGCCGGGAGCGCGGCTCCCCCGGCGAGCGC
TGCGAGGAGCGCGGGGGAGACCCGGCCGTCTCGCCTGGGGGGCCCCCGCTGGGCCTGGGGCCGC
CGCCGCGCTACCCCGGCAGCCTGGACGGGCCCGGCGCGGGCGGCGACGGCGACGACTACAAGAG
CAGCAGCGAGGAGACGGGCAGCAGCGAGGACCCCAGCCCTCCCGGCGGCCACCTGGAGGGCTAC
CCCTGCCCGCACCTGGCTTACGGCGAGCCGGAGAGCTTCGGGGACAACTTATACGTGTGCATCC
CGTGCGGCAAGGGCTTCCCCAGCTCCGAGCAGCTGAACGCGCACGTGGAGGCTCACGTAGAGGA
GGAGGAGGCGCTGTACGGCAGGGCCGAGGCGGCTGAGGTGGCGGCCGGGCCCCCTTTTGGGAGC
GGTGCGGACAAGGTCGCTGGGGCTCCGGGCAGCCTAGGAGAGCTGCTGCGGCCATACCGCTGCG
CGTCCTGCGACAAGAGCTACAAGGACCCGGCCACGCTGCGGCAGCACGAGAAGACGCACTGGCT
GACCCGGCCTTATCCATGCACCATATGCGGGAAGAAGTTCACGCAACGCGGGACCATGACGCGC
CACATGCGCAGCCACCTGGGCCTCAAGCCCTTTGCGTGCGACGCGTGCGGCATGCGCTTCACGC
GCCAGTACCGCCTCACGGAGCACATGCGCATCCACTCGGGCGAGAAGCCCTACGAGTGCCAAGT
GTGCGGCGGCAAGTTCGCACAGCAACGCAACCTCATCAGCCACATGAAGATGCACGCCGTGGGC
GGCGCGGCCGGCGCGGCCGGGGCGCTGGCAGGTCTAGGGGGCCTACCCGGCGTCCCCGGCCCCG
ACGGCAAAGGCAAGCTTGACTTCCCCGAGGGCGTCTTTGCTGTGGCCCGCCTCACGGCGGAACA
GCTGAGCCTGAAGCAGCAGGACAAGGCGGCTGCGGCCGAGCTGCTGGCGCAGACCACGCACTTC
CTGCACGACCCCAAGGTGGCGCTCGAGAGCCTCTACCCGCTGGCCAAGTTCACGGCGGAGCTGG
GCCTCAGCCCAGACAAGGCGGCGGAGGTGCTGAGCCAGGGCGCTCACCTGGCCGCGGGTCCCGA
CGGCCGGACCATCGACCGTTTCTCTCCCACCTAGAGCACCTCTCGCCGGCCCTCCTTGCCGCCG
CCCCGCGCGCGGCCCGGCCC

hide sequence

RefSeq Acc Id:

XM_005402597 ⟹ XP_005402654

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	1,179,015 - 1,182,936 (-)	NCBI

Sequence:

show sequence

TAAGAGTGTGCGGAAAGCGCGGCGGGGCTGAGACGCGACCAGGACGCGGGGAGGACGGACCAGC
AGGACAGACCGACCGGGGGCCCGGCGGGCGGAGGGCAGCGCAGCGCAGCCACGTCCCCCCCTGG
ATCCGCCGGCAGCCGGGCCCGGGGCTTCCGACATGCCCCCCAGGAGAGTGTGCTGGGCAGACGA
TGCTGGACACGATGGAGGCGCCCGGCCACTCGAGGCAGCTGCTGCTGCAGCTCAACAACCAGCG
CACCAAGGGCTTCTTGTGCGACGTGATCATCGTGGTGCAAAACGCCCTCTTCCGCGCGCACAAG
AACGTGCTGGCGGCCAGCAGTGCCTACCTCAAGTCCCTGGTGGTGCATGACAACCTGCTCAACC
TGGACCATGACATGGTGAGCCCGGCCGTGTTCCGCCTGGTGCTGGACTTCATCTACACCGGCCG
TCTGGCTGACGGTGCAGAGGCAGCTGCAGCGGCGGCCGTGGCCCCAGGGGCCGAGCCGAGCCTG
GGTGCGGTGCTGGCCGCAGCCAGCTACCTGCAGATCCCTGACCTCGTGGCGCTGTGCAAGAAGC
GCCTCAAGCGCCACGGCAAGTACTGTCACCTGAGGGGAGGTGGCAGCGGTGGCGGCGGTTATGC
GCCCTACGGGAGGCCGGGCCGTGGCCTGAGGGCCGCCACGCCCGTCATTCAGACCTGCTACTCG
TCTCCAGCCGGGCCCCCGCCACCGCCCACCTCCGAGCCGCCGTCGGGCCCCGAGGCCTCGGTCA
ACACGCACTGTGCAGAGCTGTACGCCTCGGGGCCCGGCCCCGCCGCCGCGCTGTGCGCCCCAGA
GCGCCGCTGCTCTCCGCTCTGCGGCCTGGACCTATCCAAGAAGAGCCCGCCCGGCTCTGCGGTT
CCCGAGCGGCCCCTGAGTGAGCGCGACCTGCCCCCGCGGCCCGACAGCCCTCCCAGCGCGGGCC
CCGCCGCCTACAAGGAGCCCCCGCTCGCCCTGCCGCCGCTGCCGCCGCTGCCCTTCCAAAAGCT
GGAGGAGGCCGCGCCCCCGCCGGACCCGTTTCGCGGCAGCGGCGGCAGCCCGGGACCCGAGCCC
CCCGGCCGCCCCGACGGGCCCAGCCTCCTCTACCGCTGGATGAAGCACGAGCCGGGGCTGAGCA
GCTACGGGGACGAGCTGAGCCGGGAGCGCGGCTCCCCCGGCGAGCGCTGCGAGGAGCGCGGGGG
AGACCCGGCCGTCTCGCCTGGGGGGCCCCCGCTGGGCCTGGGGCCGCCGCCGCGCTACCCCGGC
AGCCTGGACGGGCCCGGCGCGGGCGGCGACGGCGACGACTACAAGAGCAGCAGCGAGGAGACGG
GCAGCAGCGAGGACCCCAGCCCTCCCGGCGGCCACCTGGAGGGCTACCCCTGCCCGCACCTGGC
TTACGGCGAGCCGGAGAGCTTCGGGGACAACTTATACGTGTGCATCCCGTGCGGCAAGGGCTTC
CCCAGCTCCGAGCAGCTGAACGCGCACGTGGAGGCTCACGTAGAGGAGGAGGAGGCGCTGTACG
GCAGGGCCGAGGCGGCTGAGGTGGCGGCCGGGCCCCCTTTTGGGAGCGGTGCGGACAAGGTCGC
TGGGGCTCCGGGCAGCCTAGGAGAGCTGCTGCGGCCATACCGCTGCGCGTCCTGCGACAAGAGC
TACAAGGACCCGGCCACGCTGCGGCAGCACGAGAAGACGCACTGGCTGACCCGGCCTTATCCAT
GCACCATATGCGGGAAGAAGTTCACGCAACGCGGGACCATGACGCGCCACATGCGCAGCCACCT
GGGCCTCAAGCCCTTTGCGTGCGACGCGTGCGGCATGCGCTTCACGCGCCAGTACCGCCTCACG
GAGCACATGCGCATCCACTCGGGCGAGAAGCCCTACGAGTGCCAAGTGTGCGGCGGCAAGTTCG
CACAGCAACGCAACCTCATCAGCCACATGAAGATGCACGCCGTGGGCGGCGCGGCCGGCGCGGC
CGGGGCGCTGGCAGGTCTAGGGGGCCTACCCGGCGTCCCCGGCCCCGACGGCAAAGGCAAGCTT
GACTTCCCCGAGGGCGTCTTTGCTGTGGCCCGCCTCACGGCGGAACAGCTGAGCCTGAAGCAGC
AGGACAAGGCGGCTGCGGCCGAGCTGCTGGCGCAGACCACGCACTTCCTGCACGACCCCAAGGT
GGCGCTCGAGAGCCTCTACCCGCTGGCCAAGTTCACGGCGGAGCTGGGCCTCAGCCCAGACAAG
GCGGCGGAGGTGCTGAGCCAGGGCGCTCACCTGGCCGCGGGTCCCGACGGCCGGACCATCGACC
GTTTCTCTCCCACCTAGAGCACCTCTCGCCGGCCCTCCTTGCCGCCGCCCCGCGCGCGGCCCGG
CCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005402652	(Get FASTA)	NCBI Sequence Viewer
	XP_005402653	(Get FASTA)	NCBI Sequence Viewer
	XP_005402654	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000011707
	ENSCLAP00000011707.1

RefSeq Acc Id:

XP_005402654 ⟸ XM_005402597

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLN
LDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIPDLVALCKK
RLKRHGKYCHLRGGGSGGGGYAPYGRPGRGLRAATPVIQTCYSSPAGPPPPPTSEPPSGPEASV
NTHCAELYASGPGPAAALCAPERRCSPLCGLDLSKKSPPGSAVPERPLSERDLPPRPDSPPSAG
PAAYKEPPLALPPLPPLPFQKLEEAAPPPDPFRGSGGSPGPEPPGRPDGPSLLYRWMKHEPGLS
SYGDELSRERGSPGERCEERGGDPAVSPGGPPLGLGPPPRYPGSLDGPGAGGDGDDYKSSSEET
GSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALY
GRAEAAEVAAGPPFGSGADKVAGAPGSLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYP
CTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKF
AQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQ
QDKAAAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAAGPDGRTID
RFSPT

hide sequence

RefSeq Acc Id:

XP_005402653 ⟸ XM_005402596

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLN
LDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIPDLVALCKK
RLKRHGKYCHLRGGGSGGGGYAPYGRPGRGLRAATPVIQTCYSSPAGPPPPPTSEPPSGPEASV
NTHCAELYASGPGPAAALCAPERRCSPLCGLDLSKKSPPGSAVPERPLSERDLPPRPDSPPSAG
PAAYKEPPLALPPLPPLPFQKLEEAAPPPDPFRGSGGSPGPEPPGRPDGPSLLYRWMKHEPGLS
SYGDELSRERGSPGERCEERGGDPAVSPGGPPLGLGPPPRYPGSLDGPGAGGDGDDYKSSSEET
GSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALY
GRAEAAEVAAGPPFGSGADKVAGAPGSLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYP
CTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKF
AQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQ
QDKAAAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAAGPDGRTID
RFSPT

hide sequence

RefSeq Acc Id:	XP_005402652 ⟸ XM_005402595
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VAE1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTFPEADILLKSGECAGQTMLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNV LAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGA VLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGSGGGGYAPYGRPGRGLRAATPVIQTCYSSP AGPPPPPTSEPPSGPEASVNTHCAELYASGPGPAAALCAPERRCSPLCGLDLSKKSPPGSAVPE RPLSERDLPPRPDSPPSAGPAAYKEPPLALPPLPPLPFQKLEEAAPPPDPFRGSGGSPGPEPPG RPDGPSLLYRWMKHEPGLSSYGDELSRERGSPGERCEERGGDPAVSPGGPPLGLGPPPRYPGSL DGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPS SEQLNAHVEAHVEEEEALYGRAEAAEVAAGPPFGSGADKVAGAPGSLGELLRPYRCASCDKSYK DPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEH MRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDF PEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPDKAA EVLSQGAHLAAGPDGRTIDRFSPT hide sequence

RefSeq Acc Id:

ENSCLAP00000011707 ⟸ ENSCLAT00000011845

Protein Domains

BTB C2H2-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000008072	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000011845	ENTREZGENE
	ENSCLAT00000011845.1	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	BTB/POZ_dom	UniProtKB/TrEMBL
	SKP1/BTB/POZ_sf	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
NCBI Gene	Hic1	ENTREZGENE
PANTHER	HYPERMETHYLATED IN CANCER 1 PROTEIN	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN	UniProtKB/TrEMBL
Pfam	BTB	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	BTB	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54695	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A0A8C2VAE1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-10-11	Hic1	HIC ZBTB transcriptional repressor 1		hypermethylated in cancer 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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