Med13l (mediator complex subunit 13L) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Med13l (mediator complex subunit 13L) Rattus norvegicus
Analyze
Symbol: Med13l
Name: mediator complex subunit 13L
RGD ID: 1305884
Description: Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of mediator complex. Human ortholog(s) of this gene implicated in dextro-looped transposition of the great arteries. Orthologous to human MED13L (mediator complex subunit 13L); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360817; mediator complex subunit 13-like; mediator of RNA polymerase II transcription subunit 13-like; Thrap2; thyroid hormone receptor associated protein 2; thyroid hormone receptor-associated 240-like protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,468,556 - 43,665,819 (-)NCBIGRCr8
mRatBN7.21237,807,596 - 38,004,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1237,808,285 - 38,004,473 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01243,421,317 - 43,576,859 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1243,421,308 - 43,576,804 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,257,715 - 45,412,653 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,136,265 - 39,181,221 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11239,012,458 - 39,153,750 (-)NCBI
Celera1239,469,893 - 39,630,500 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatdextro-looped transposition of the great arteries  ISORGD:13141831580649 RGD 
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatAu-Kline Syndrome  ISORGD:13141838554872ClinVar Annotator: match by term: Kabuki-like syndromeClinVarPMID:25741868
Med13lRatautism spectrum disorder  ISORGD:13141838554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:30504930
Med13lRatDevelopmental Disabilities  ISORGD:13141838554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25712080|PMID:25741868|PMID:25741884|PMID:25758992|PMID:28492532|PMID:31785789
Med13lRatdextro-looped transposition of the great arteries  ISORGD:13141838554872ClinVar Annotator: match by term: Transposition of the great arteries, dextro-loopedClinVarPMID:14638541|PMID:16199547|PMID:17576681|PMID:21937992|PMID:23403903|PMID:24267886|PMID:24781760|PMID:24896178|PMID:25137640|PMID:25167861|PMID:25356899|PMID:25712080|PMID:25741868|PMID:25741884|PMID:25758992|PMID:27824329|PMID:27899622|PMID:28371282|PMID:28492532|PMID:28554332|PMID:28588821|PMID:28645799|PMID:29159987|PMID:29346770|PMID:29511999|PMID:29959045|PMID:30564305|PMID:31144778|PMID:31171384|PMID:31618753|PMID:31785789|PMID:35982159|PMID:35982160|PMID:36135330|PMID:36798993|PMID:5167861|PMID:9536098
Med13lRatgenetic disease  ISORGD:13141838554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:12738880|PMID:14638541|PMID:23403903|PMID:24267886|PMID:24781760|PMID:24896178|PMID:25137640|PMID:25167861|PMID:25356899|PMID:25712080|PMID:25741868|PMID:25758992|PMID:27899622|PMID:28371282|PMID:28492532|PMID:28588821|PMID:28645799|PMID:29159987|PMID:29511999|PMID:31171384|PMID:5167861
Med13lRatintellectual disability  ISORGD:13141838554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:23403903|PMID:25167861|PMID:25741868|PMID:28492532|PMID:29511999
Med13lRatMarfanoid Mental Retardation Syndrome, Autosomal  ISORGD:13141838554872ClinVar Annotator: match by term: Marfanoid habitus and intellectual disabilityClinVarPMID:25741868
Med13lRatMental Retardation and Distinctive Facial Features with or without Cardiac Defects  ISORGD:13141838554872ClinVar Annotator: match by term: Cardiac anomalies - developmental delay - facial dysmorphism syndrome | more ...ClinVarPMID:14638541|PMID:17576681|PMID:22542183|PMID:23403903|PMID:24781716|PMID:24781760|PMID:24896178|PMID:25167861|PMID:25712080|PMID:25741868|PMID:25741869|PMID:25758992|PMID:26046367|PMID:27500536|PMID:28492532|PMID:28554332|PMID:28645799|PMID:28708303|PMID:29511999|PMID:29758562|PMID:30504930|PMID:31785789|PMID:35887114|PMID:35982159|PMID:35982160|PMID:36135330|PMID:36798993|PMID:39825153|PMID:9536098
Med13lRatNeurodevelopmental Disorders  ISORGD:13141838554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25712080|PMID:25741868|PMID:25758992|PMID:28492532|PMID:29959045
Med13lRatstrabismus  ISORGD:13141838554872ClinVar Annotator: match by term: StrabismusClinVarPMID:25741868
Med13lRatvesicoureteral reflux  ISORGD:13141838554872ClinVar Annotator: match by term: Vesico-Ureteral RefluxClinVarPMID:25741868
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatintellectual disability  ISORGD:131418311554173CTD Direct Evidence: marker/mechanismCTDPMID:21937992
Med13lRatNeurodevelopmental Disorders  ISORGD:131418311554173CTD Direct Evidence: marker/mechanismCTDPMID:28191889
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatMental Retardation and Distinctive Facial Features with or without Cardiac Defects  ISORGD:13141837240710 OMIM 

1 to 20 of 113 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRat(-)-demecolcine increases expressionISORGD:13141836480464Demecolcine results in increased expression of MED13L mRNACTDPMID:23649840
Med13lRat(-)-epigallocatechin 3-gallate multiple interactionsISORGD:13141836480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MED13L mRNACTDPMID:22079256
Med13lRat(1->4)-beta-D-glucan multiple interactionsISORGD:16182756480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of MED13L mRNACTDPMID:36331819
Med13lRat1,2-dimethylhydrazine increases expressionISORGD:161827564804641,2-Dimethylhydrazine results in increased expression of MED13L mRNACTDPMID:22206623
Med13lRat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of MED13L mRNACTDPMID:32145629
Med13lRat17beta-estradiol increases expressionISORGD:13141836480464Estradiol results in increased expression of MED13L mRNACTDPMID:31614463
Med13lRat2,2',5,5'-tetrachlorobiphenyl decreases expressionEXP 64804642,5,2',5'-tetrachlorobiphenyl results in decreased expression of MED13L mRNACTDPMID:23829299
Med13lRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:16182756480464Tetrachlorodibenzodioxin results in decreased expression of MED13L mRNACTDPMID:17337447
Med13lRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MED13L mRNACTDPMID:34747641
Med13lRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:13141836480464[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of MED13L mRNACTDPMID:29704546
Med13lRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:16182756480464Tetrachlorodibenzodioxin affects the expression of MED13L mRNACTDPMID:21570461|PMID:24680724
Med13lRat3,4-methylenedioxymethamphetamine decreases expressionISORGD:16182756480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of MED13L mRNACTDPMID:20188158|PMID:26251327
Med13lRat3-methylcholanthrene multiple interactionsISORGD:13141836480464Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter]CTDPMID:20348232
Med13lRat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641,2-dithiol-3-thione results in decreased expression of MED13L mRNACTDPMID:19162173
Med13lRat4,4'-sulfonyldiphenol decreases expressionISORGD:16182756480464bisphenol S results in decreased expression of MED13L mRNACTDPMID:39298647
Med13lRat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ...CTDPMID:36041667
Med13lRat4,4'-sulfonyldiphenol decreases methylationISORGD:13141836480464bisphenol S results in decreased methylation of MED13L geneCTDPMID:31601247
Med13lRat5-fluorouracil multiple interactionsISORGD:13141836480464MED13L mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with more ...CTDPMID:16896004
Med13lRataflatoxin B1 decreases methylationISORGD:13141836480464Aflatoxin B1 results in decreased methylation of MED13L geneCTDPMID:27153756
Med13lRataristolochic acid A decreases expressionISORGD:13141836480464aristolochic acid I results in decreased expression of MED13L mRNA; aristolochic acid I results in more ...CTDPMID:33212167

1 to 20 of 113 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatbiological_process  ND 159840712/2014: no relevant rat dataRGD 
Med13lRatpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q71F56|ensembl:ENSP000002819281600115GO_REF:0000107EnsemblGO_REF:0000107
Med13lRatpositive regulation of transcription by RNA polymerase II involved_inISORGD:13141831624291 PMID:22249253RGDPMID:22249253
Med13lRatregulation of transcription by RNA polymerase II involved_inIEAInterPro:IPR0094011600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatmediator complex part_ofIEAInterPro:IPR0094011600115GO_REF:0000002InterProGO_REF:0000002
Med13lRatmediator complex part_ofISORGD:16182751624291 PMID:12093747RGDPMID:12093747
Med13lRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Med13lRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRattranscription coactivator activity enablesIEAUniProtKB:Q71F56|ensembl:ENSP000002819281600115GO_REF:0000107EnsemblGO_REF:0000107
Med13lRattranscription coactivator activity enablesISORGD:13141831624291 PMID:22249253RGDPMID:22249253
Med13lRattranscription coregulator activity enablesIEAInterPro:IPR0094011600115GO_REF:0000002InterProGO_REF:0000002

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Med13lRatRNA polymerase II transcription pathway   ISORGD:13141839681732 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Missense mutations and gene interruption in PROSIT240, a novel TRAP240-like gene, in patients with congenital heart defect (transposition of the great arteries). Muncke N, etal., Circulation. 2003 Dec 9;108(23):2843-50. Epub 2003 Nov 24.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:12093747  



Med13l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,468,556 - 43,665,819 (-)NCBIGRCr8
mRatBN7.21237,807,596 - 38,004,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1237,808,285 - 38,004,473 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01243,421,317 - 43,576,859 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1243,421,308 - 43,576,804 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,257,715 - 45,412,653 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,136,265 - 39,181,221 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11239,012,458 - 39,153,750 (-)NCBI
Celera1239,469,893 - 39,630,500 (-)NCBICelera
Cytogenetic Map12q16NCBI
MED13L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812115,958,576 - 116,277,693 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12115,957,905 - 116,277,693 (-)EnsemblGRCh38hg38GRCh38
GRCh3712116,396,381 - 116,715,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612114,880,764 - 115,199,526 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412114,859,102 - 115,177,863NCBI
Celera12116,025,985 - 116,344,576 (-)NCBICelera
Cytogenetic Map12q24.21NCBI
HuRef12113,407,355 - 113,687,093 (-)NCBIHuRef
CHM1_112116,364,171 - 116,682,739 (-)NCBICHM1_1
T2T-CHM13v2.012115,939,568 - 116,258,754 (-)NCBIT2T-CHM13v2.0
Med13l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395118,698,363 - 118,903,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5118,698,744 - 118,903,503 (+)EnsemblGRCm39 Ensembl
GRCm385118,560,330 - 118,765,438 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5118,560,679 - 118,765,438 (+)EnsemblGRCm38mm10GRCm38
MGSCv375119,010,728 - 119,215,447 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365118,821,773 - 119,024,010 (+)NCBIMGSCv36mm8
Celera5115,689,167 - 115,861,251 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map559.1NCBI
Med13l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545514,679,416 - 14,957,532 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545514,679,416 - 14,960,226 (+)NCBIChiLan1.0ChiLan1.0
MED13L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210124,015,884 - 124,335,362 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112124,012,262 - 124,331,735 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012113,531,181 - 113,850,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112116,906,557 - 117,187,192 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12116,909,244 - 117,065,649 (-)Ensemblpanpan1.1panPan2
MED13L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12612,768,762 - 13,031,251 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2612,770,588 - 13,030,512 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2612,764,292 - 13,059,638 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02613,028,568 - 13,324,202 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2613,029,858 - 13,324,593 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12612,990,722 - 13,286,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02613,073,281 - 13,365,481 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02613,102,596 - 13,397,898 (-)NCBIUU_Cfam_GSD_1.0
Med13l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118153,190,760 - 153,480,666 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365585,998,754 - 6,289,867 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365585,998,760 - 6,288,666 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED13L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1436,063,644 - 36,383,800 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11436,061,834 - 36,384,567 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21438,298,853 - 38,578,678 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MED13L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111111,245,201 - 111,563,485 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11111,243,753 - 111,563,663 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037133,499,321 - 133,817,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Med13l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474716,810,076 - 17,118,088 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474716,810,123 - 17,120,758 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Med13l
777 total Variants

Predicted Target Of
Summary Value
Count of predictions:77
Count of miRNA genes:70
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000042331
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat

1 to 10 of 45 rows
RH143248  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,808,538 - 37,808,759 (+)MAPPERmRatBN7.2
Rnor_6.01243,422,260 - 43,422,480NCBIRnor6.0
Rnor_5.01245,258,658 - 45,258,878UniSTSRnor5.0
RGSC_v3.41239,137,208 - 39,137,428UniSTSRGSC3.4
Celera1239,470,836 - 39,471,056UniSTS
RH 3.4 Map12692.7UniSTS
Cytogenetic Map12q16UniSTS
BI291178  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,809,800 - 37,809,991 (+)MAPPERmRatBN7.2
Rnor_6.01243,423,522 - 43,423,712NCBIRnor6.0
Rnor_5.01245,259,920 - 45,260,110UniSTSRnor5.0
RGSC_v3.41239,138,470 - 39,138,660UniSTSRGSC3.4
Celera1239,472,098 - 39,472,288UniSTS
RH 3.4 Map10583.6UniSTS
Cytogenetic Map12q16UniSTS
AI717557  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81243,599,629 - 43,600,623 (+)Marker Load Pipeline
mRatBN7.21237,938,680 - 37,939,674 (+)MAPPERmRatBN7.2
Rnor_6.01243,549,226 - 43,550,219NCBIRnor6.0
Rnor_5.01245,385,647 - 45,386,640UniSTSRnor5.0
Celera1239,602,835 - 39,603,828UniSTS
RH 3.4 Map12701.5UniSTS
Cytogenetic Map12q16UniSTS
BE116030  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,820,414 - 37,820,580 (+)MAPPERmRatBN7.2
Rnor_6.01243,434,169 - 43,434,334NCBIRnor6.0
Rnor_5.01245,270,567 - 45,270,732UniSTSRnor5.0
RGSC_v3.41239,149,118 - 39,149,283UniSTSRGSC3.4
Celera1239,483,334 - 39,483,499UniSTS
RH 3.4 Map12702.4UniSTS
Cytogenetic Map12q16UniSTS
RH140782  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,809,205 - 37,809,348 (+)MAPPERmRatBN7.2
Rnor_6.01243,422,927 - 43,423,069NCBIRnor6.0
Rnor_5.01245,259,325 - 45,259,467UniSTSRnor5.0
RGSC_v3.41239,137,875 - 39,138,017UniSTSRGSC3.4
Celera1239,471,503 - 39,471,645UniSTS
RH 3.4 Map12703.4UniSTS
Cytogenetic Map12q16UniSTS
BE119619  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,859,388 - 37,859,544 (+)MAPPERmRatBN7.2
Rnor_6.01243,473,084 - 43,473,239NCBIRnor6.0
Rnor_5.01245,309,482 - 45,309,637UniSTSRnor5.0
Celera1239,522,102 - 39,522,257UniSTS
RH 3.4 Map12695.9UniSTS
Cytogenetic Map12q16UniSTS
AI717557  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,939,652 - 37,939,825 (+)MAPPERmRatBN7.2
Rnor_6.01243,550,198 - 43,550,370NCBIRnor6.0
Rnor_5.01245,386,619 - 45,386,791UniSTSRnor5.0
Celera1239,603,807 - 39,603,979UniSTS
RH 3.4 Map12701.5UniSTS
Cytogenetic Map12q16UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 17 of 17 rows
RefSeq Transcripts NM_001419791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU566026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 17 of 17 rows

Ensembl Acc Id: ENSRNOT00000042331   ⟹   ENSRNOP00000046404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,808,285 - 37,966,245 (-)Ensembl
Rnor_6.0 Ensembl1243,423,905 - 43,576,754 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078445   ⟹   ENSRNOP00000073531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,808,285 - 37,892,151 (-)Ensembl
Rnor_6.0 Ensembl1243,421,308 - 43,503,456 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081780   ⟹   ENSRNOP00000070275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,808,285 - 37,966,328 (-)Ensembl
Rnor_6.0 Ensembl1243,423,905 - 43,576,804 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120071   ⟹   ENSRNOP00000092543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,808,285 - 38,004,473 (-)Ensembl
RefSeq Acc Id: NM_001419791   ⟹   NP_001406720
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,819 (-)NCBI
mRatBN7.21237,807,596 - 38,004,886 (-)NCBI
RefSeq Acc Id: XM_039090172   ⟹   XP_038946100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,425 (-)NCBI
mRatBN7.21237,807,596 - 38,004,485 (-)NCBI
RefSeq Acc Id: XM_039090173   ⟹   XP_038946101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,425 (-)NCBI
mRatBN7.21237,807,596 - 38,004,485 (-)NCBI
RefSeq Acc Id: XM_039090175   ⟹   XP_038946103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,262 (-)NCBI
mRatBN7.21237,807,596 - 38,004,320 (-)NCBI
RefSeq Acc Id: XM_063271538   ⟹   XP_063127608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,468,556 - 43,665,262 (-)NCBI
Ensembl Acc Id: ENSRNOP00000073531   ⟸   ENSRNOT00000078445
Ensembl Acc Id: ENSRNOP00000070275   ⟸   ENSRNOT00000081780
Ensembl Acc Id: ENSRNOP00000046404   ⟸   ENSRNOT00000042331
RefSeq Acc Id: XP_038946101   ⟸   XM_039090173
- Peptide Label: isoform X2
- UniProtKB: D4P4K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946100   ⟸   XM_039090172
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AID1 (UniProtKB/TrEMBL),   D4P4K6 (UniProtKB/TrEMBL)
Mediator complex subunit Med13 C-terminal   Mediator complex subunit Med13 N-terminal   MID

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JXH7-F1-model_v2 AlphaFold A0A0G2JXH7 1-2189 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19108 BioCyc
Ensembl Genes ENSRNOG00000001120 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042331 ENTREZGENE
  ENSRNOT00000042331.5 UniProtKB/TrEMBL
  ENSRNOT00000078445 ENTREZGENE
  ENSRNOT00000078445.2 UniProtKB/TrEMBL
  ENSRNOT00000081780.2 UniProtKB/TrEMBL
  ENSRNOT00000120071.1 UniProtKB/TrEMBL
InterPro Mediator_complx_sub13 UniProtKB/TrEMBL
  Mediator_Med13 UniProtKB/TrEMBL
  Mediator_Med13_N UniProtKB/TrEMBL
  MID_MedPIWI UniProtKB/TrEMBL
NCBI Gene 360817 ENTREZGENE
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 UniProtKB/TrEMBL
  MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE UniProtKB/TrEMBL
Pfam Med13_C UniProtKB/TrEMBL
  Med13_N UniProtKB/TrEMBL
  MID_MedPIWI UniProtKB/TrEMBL
PhenoGen Med13l PhenoGen
RatGTEx ENSRNOG00000001120 RatGTEx
UniProt A0A0G2JXH7_RAT UniProtKB/TrEMBL
  A0A0G2K5R7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AID1 ENTREZGENE, UniProtKB/TrEMBL
  D4P4K6 ENTREZGENE, UniProtKB/TrEMBL
  F1LZT8_RAT UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-08-13 Med13l  mediator complex subunit 13L  Med13l  mediator complex subunit 13-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Med13l  mediator complex subunit 13-like  Thrap2_predicted  thyroid hormone receptor associated protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Thrap2_predicted  thyroid hormone receptor associated protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED