Gsn (gelsolin) - Rat Genome Database

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Gene: Gsn (gelsolin) Chinchilla lanigera
Analyze
Symbol: Gsn
Name: gelsolin
RGD ID: 8767145
Description: ENCODES a protein that exhibits actin binding (ortholog); calcium ion binding (ortholog); myosin II binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament capping (ortholog); actin filament depolymerization (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; N-cadherin signaling pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Liver Failure (ortholog); amyloidosis (ortholog); FOUND IN actin cap (ortholog); actin cytoskeleton (ortholog); apical ectoplasmic specialization (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plasma gelsolin
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554196,682,058 - 6,733,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554196,682,202 - 6,733,361 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gsn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554196,682,058 - 6,733,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554196,682,202 - 6,733,361 (-)NCBIChiLan1.0ChiLan1.0
GSN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389121,201,483 - 121,332,842 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9121,207,794 - 121,332,843 (+)EnsemblGRCh38hg38GRCh38
GRCh379123,963,761 - 124,095,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369123,070,201 - 123,134,941 (+)NCBINCBI36Build 36hg18NCBI36
Build 349121,109,960 - 121,174,674NCBI
Celera994,678,898 - 94,743,628 (+)NCBICelera
Cytogenetic Map9q33.2NCBI
HuRef993,648,171 - 93,712,883 (+)NCBIHuRef
CHM1_19124,177,269 - 124,242,004 (+)NCBICHM1_1
T2T-CHM13v2.09133,397,510 - 133,528,852 (+)NCBIT2T-CHM13v2.0
Gsn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39235,146,371 - 35,197,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl235,146,392 - 35,197,904 (+)EnsemblGRCm39 Ensembl
GRCm38235,256,359 - 35,307,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl235,256,380 - 35,307,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv37235,137,960 - 35,163,412 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36235,104,449 - 35,129,901 (+)NCBIMGSCv36mm8
Celera234,977,113 - 35,002,613 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map223.5NCBI
Gsn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8338,982,605 - 39,035,849 (+)NCBIGRCr8
mRatBN7.2318,585,166 - 18,638,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl318,585,172 - 18,638,402 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx321,683,799 - 21,710,538 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0330,268,837 - 30,295,574 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0328,522,714 - 28,549,446 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0314,456,106 - 14,508,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl314,467,330 - 14,508,911 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0319,773,655 - 19,826,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4314,360,245 - 14,386,313 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1314,256,616 - 14,282,685 (+)NCBI
Celera313,325,045 - 13,351,501 (+)NCBICelera
Cytogenetic Map3p11NCBI
GSN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,011,809 - 18,076,682 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1918,014,159 - 18,079,040 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0992,413,819 - 92,460,483 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19120,741,148 - 120,805,831 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9120,741,148 - 120,805,831 (+)Ensemblpanpan1.1panPan2
GSN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11174,248,227 - 74,268,129 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1174,233,457 - 74,268,129 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1172,637,556 - 72,678,974 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01175,364,194 - 75,405,704 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1175,364,181 - 75,405,705 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11173,871,291 - 73,912,586 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01173,902,056 - 73,943,469 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01174,663,262 - 74,683,140 (+)NCBIUU_Cfam_GSD_1.0
Gsn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947189,981,162 - 190,034,252 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364879,764,944 - 9,802,841 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364879,749,755 - 9,802,787 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1261,307,008 - 261,372,848 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11261,295,711 - 261,372,848 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21293,381,825 - 293,388,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11218,253,079 - 18,317,285 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1218,253,324 - 18,285,938 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603524,700,374 - 24,764,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gsn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476013,943,888 - 13,969,905 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476013,943,680 - 14,004,660 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000013941   ⟹   ENSCLAP00000013786
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554196,682,058 - 6,733,361 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000013942   ⟹   ENSCLAP00000013787
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554196,682,058 - 6,706,604 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000013943   ⟹   ENSCLAP00000013788
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554196,682,441 - 6,706,433 (-)Ensembl
RefSeq Acc Id: XM_005382570   ⟹   XP_005382627
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554196,682,202 - 6,706,486 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513254   ⟹   XP_013368708
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554196,682,202 - 6,733,361 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513255   ⟹   XP_013368709
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554196,682,202 - 6,733,361 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005382627 (Get FASTA)   NCBI Sequence Viewer  
  XP_013368708 (Get FASTA)   NCBI Sequence Viewer  
  XP_013368709 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAS59421 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013786.1
  ENSCLAP00000013787
  ENSCLAP00000013787.1
  ENSCLAP00000013788
  ENSCLAP00000013788.1
RefSeq Acc Id: XP_005382627   ⟸   XM_005382570
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VD06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368709   ⟸   XM_013513255
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VD38 (UniProtKB/TrEMBL),   A0A8C2VD06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368708   ⟸   XM_013513254
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VD06 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000013786   ⟸   ENSCLAT00000013941
Ensembl Acc Id: ENSCLAP00000013787   ⟸   ENSCLAT00000013942
Ensembl Acc Id: ENSCLAP00000013788   ⟸   ENSCLAT00000013943
Protein Domains
Gelsolin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009527 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013941.1 UniProtKB/TrEMBL
  ENSCLAT00000013942 ENTREZGENE
  ENSCLAT00000013942.1 UniProtKB/TrEMBL
  ENSCLAT00000013943 ENTREZGENE
  ENSCLAT00000013943.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/TrEMBL
InterPro ADF-H/Gelsolin-like_dom_sf UniProtKB/TrEMBL
  Gelsolin-like_dom UniProtKB/TrEMBL
  Villin/Gelsolin UniProtKB/TrEMBL
NCBI Gene Gsn ENTREZGENE
PANTHER GELSOLIN UniProtKB/TrEMBL
  PTHR11977 UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/TrEMBL
PRINTS GELSOLIN UniProtKB/TrEMBL
SMART GEL UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/TrEMBL
UniProt A0A8C2VD06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VD37_CHILA UniProtKB/TrEMBL
  A0A8C2VD38 ENTREZGENE, UniProtKB/TrEMBL