Gdnf (glial cell derived neurotrophic factor) - Rat Genome Database

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Gene: Gdnf (glial cell derived neurotrophic factor) Chinchilla lanigera
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Symbol: Gdnf
Name: glial cell derived neurotrophic factor
RGD ID: 8744389
Description: ENCODES a protein that exhibits glial cell-derived neurotrophic factor receptor binding (ortholog); growth factor activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); cell population proliferation (ortholog); cellular response to dexamethasone stimulus (ortholog); ASSOCIATED WITH acoustic neuroma (ortholog); Alzheimer's disease (ortholog); amphetamine abuse (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: glial cell line-derived neurotrophic factor
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542622,386,450 - 22,412,324 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542622,386,613 - 22,412,324 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
branching involved in ureteric bud morphogenesis  (ISO)
cell population proliferation  (ISO)
cellular response to dexamethasone stimulus  (ISO)
commissural neuron axon guidance  (ISO)
dorsal spinal cord development  (ISO)
embryonic organ development  (ISO)
enteric nervous system development  (ISO)
male gonad development  (ISO)
mesenchymal to epithelial transition involved in metanephros morphogenesis  (ISO)
metanephros development  (ISO)
midbrain development  (ISO)
mRNA stabilization  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
negative regulation of neuron apoptotic process  (ISO)
nervous system development  (ISO)
neural crest cell migration  (ISO)
neuron differentiation  (ISO)
neuron projection development  (ISO)
organ induction  (ISO)
peripheral nervous system development  (ISO)
peristalsis  (ISO)
positive regulation of branching involved in ureteric bud morphogenesis  (ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis  (ISO)
positive regulation of monooxygenase activity  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of ureteric bud formation  (ISO)
postganglionic parasympathetic fiber development  (ISO)
postsynaptic membrane organization  (ISO)
regulation of dopamine uptake involved in synaptic transmission  (ISO)
regulation of gene expression  (ISO)
regulation of morphogenesis of a branching structure  (ISO)
regulation of semaphorin-plexin signaling pathway  (ISO)
regulation of ureteric bud formation  (ISO)
response to wounding  (ISO)
retina development in camera-type eye  (ISO)
sympathetic nervous system development  (ISO)
ureteric bud development  (ISO)
ureteric bud formation  (ISO)

Cellular Component

References


Genomics

Comparative Map Data
Gdnf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542622,386,450 - 22,412,324 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542622,386,613 - 22,412,324 (-)NCBIChiLan1.0ChiLan1.0
GDNF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl537,812,677 - 37,840,041 (-)EnsemblGRCh38hg38GRCh38
GRCh38537,812,677 - 37,840,044 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37537,812,779 - 37,840,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36537,851,510 - 37,875,539 (-)NCBINCBI36hg18NCBI36
Build 34537,851,509 - 37,870,655NCBI
Celera537,699,155 - 37,726,173 (-)NCBI
Cytogenetic Map5p13.2NCBI
HuRef537,765,313 - 37,792,316 (-)NCBIHuRef
CHM1_1537,814,804 - 37,841,806 (-)NCBICHM1_1
Gdnf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39157,839,529 - 7,867,061 (+)NCBIGRCm39mm39
GRCm39 Ensembl157,840,327 - 7,867,056 (+)Ensembl
GRCm38157,810,048 - 7,837,580 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl157,810,846 - 7,837,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv37157,761,011 - 7,787,575 (+)NCBIGRCm37mm9NCBIm37
MGSCv36157,758,226 - 7,784,790 (+)NCBImm8
Celera157,656,819 - 7,683,345 (+)NCBICelera
Cytogenetic Map15A1NCBI
Gdnf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2256,893,992 - 56,919,935 (+)NCBI
Rnor_6.0 Ensembl256,887,987 - 56,910,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0256,884,181 - 56,912,964 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0276,896,991 - 76,922,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4257,399,312 - 57,424,030 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1257,327,544 - 57,352,263 (+)NCBI
Celera252,510,468 - 52,532,694 (+)NCBICelera
Cytogenetic Map2q16NCBI
GDNF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1577,573,466 - 77,600,478 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl577,577,313 - 77,601,362 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0572,539,374 - 72,566,918 (+)NCBIMhudiblu_PPA_v0panPan3
GDNF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1470,966,694 - 70,991,860 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl470,971,432 - 70,989,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0471,483,108 - 71,516,105 (+)NCBI
UMICH_Zoey_3.1471,230,252 - 71,263,217 (+)NCBI
UNSW_CanFamBas_1.0471,343,690 - 71,376,610 (+)NCBI
UU_Cfam_GSD_1.0471,882,215 - 71,915,204 (+)NCBI
Gdnf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213227,058,585 - 227,083,871 (-)NCBI
SpeTri2.0NW_0049365184,291,391 - 4,310,752 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GDNF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1622,936,601 - 22,965,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11622,936,602 - 22,965,929 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21624,176,604 - 24,179,641 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GDNF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1436,662,033 - 36,691,761 (-)NCBI
ChlSab1.1 Ensembl436,665,009 - 36,684,257 (-)Ensembl
Vero_WHO_p1.0NW_02366607127,015,956 - 27,043,442 (-)NCBI
Gdnf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475917,263,570 - 17,290,046 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000020594   ⟹   ENSCLAP00000020397
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542622,386,450 - 22,412,324 (-)Ensembl
RefSeq Acc Id: XM_005386218   ⟹   XP_005386275
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,409,865 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005386219   ⟹   XP_005386276
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,409,865 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005386220   ⟹   XP_005386277
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,391,203 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005386221   ⟹   XP_005386278
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,412,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005386222   ⟹   XP_005386279
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,407,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005386223   ⟹   XP_005386280
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,412,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013514924   ⟹   XP_013370378
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542622,386,613 - 22,407,232 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005386280   ⟸   XM_005386223
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005386278   ⟸   XM_005386221
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_005386276   ⟸   XM_005386219
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005386275   ⟸   XM_005386218
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005386279   ⟸   XM_005386222
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005386277   ⟸   XM_005386220
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013370378   ⟸   XM_013514924
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSCLAP00000020397   ⟸   ENSCLAT00000020594


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013976 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000020397 ENTREZGENE
Ensembl Transcript ENSCLAT00000020594 ENTREZGENE
NCBI Gene Gdnf ENTREZGENE