KMO (kynurenine 3-monooxygenase) - Rat Genome Database
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Gene: KMO (kynurenine 3-monooxygenase) Homo sapiens
Analyze
Symbol: KMO
Name: kynurenine 3-monooxygenase
RGD ID: 737300
HGNC Page HGNC
Description: Exhibits FAD binding activity; NAD(P)H oxidase H2O2-forming activity; and kynurenine 3-monooxygenase activity. Involved in NAD metabolic process; kynurenine metabolic process; and response to salt stress. Predicted to localize to mitochondrial outer membrane. Biomarker of schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ317G22.1; kynurenine 3-hydroxylase; kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1241,532,134 - 241,595,642 (+)EnsemblGRCh38hg38GRCh38
GRCh381241,531,883 - 241,595,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371241,695,324 - 241,758,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361239,762,330 - 239,825,566 (+)NCBINCBI36hg18NCBI36
Build 341238,021,747 - 238,084,984NCBI
Celera1214,950,683 - 215,013,947 (+)NCBI
Cytogenetic Map1q43NCBI
HuRef1212,153,669 - 212,217,265 (+)NCBIHuRef
CHM1_11242,968,145 - 243,031,623 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Alberati-Giani D, etal., FEBS Lett 1997 Jun 30;410(2-3):407-12.
2. GOA_HUMAN data from the GO Consortium
3. Maddison DC and Giorgini F, Semin Cell Dev Biol. 2015 Apr;40:134-41. doi: 10.1016/j.semcdb.2015.03.002. Epub 2015 Mar 12.
4. Mole DJ, etal., Nat Med. 2016 Feb;22(2):202-9. doi: 10.1038/nm.4020. Epub 2016 Jan 11.
5. Okayama A, etal., Toxicol Appl Pharmacol. 1988 Jul;94(3):356-61.
6. Pipeline to import KEGG annotations from KEGG into RGD
7. Pipeline to import SMPDB annotations from SMPDB into RGD
8. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. RGD automated import pipeline for gene-chemical interactions
10. Rojewska E, etal., Neuropharmacology. 2016 Mar;102:80-91. doi: 10.1016/j.neuropharm.2015.10.040. Epub 2015 Oct 31.
11. RĂ©us GZ, etal., Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 2;81:55-63. doi: 10.1016/j.pnpbp.2017.10.009. Epub 2017 Oct 13.
12. Sathyasaikumar KV, etal., Schizophr Bull. 2011 Nov;37(6):1147-56. doi: 10.1093/schbul/sbq112. Epub 2010 Oct 29.
13. Smith JR, etal., Drug Discov Today. 2016 Feb;21(2):315-24. doi: 10.1016/j.drudis.2015.11.001. Epub 2015 Nov 14.
14. Takeuchi F and Shibata Y, Biochem J. 1984 Jun 15;220(3):693-9.
15. Walker AL, etal., J Med Chem. 2017 Apr 27;60(8):3383-3404. doi: 10.1021/acs.jmedchem.7b00055. Epub 2017 Apr 11.
16. Wang J, etal., J Ethnopharmacol. 2018 Mar 25;214:13-21. doi: 10.1016/j.jep.2017.11.037. Epub 2017 Dec 5.
Additional References at PubMed
PMID:10672018   PMID:11401433   PMID:12402501   PMID:12477932   PMID:14704851   PMID:15342556   PMID:15950064   PMID:16344560   PMID:16710414   PMID:16716206   PMID:19626040   PMID:21030213  
PMID:21693093   PMID:21727251   PMID:21873635   PMID:23251661   PMID:23376485   PMID:23459468   PMID:23575632   PMID:24316190   PMID:25464917   PMID:25715464   PMID:26099564   PMID:27020856  
PMID:27077813   PMID:27503909   PMID:28139632   PMID:28319697   PMID:28514442   PMID:29208702   PMID:29429898   PMID:29961565  


Genomics

Comparative Map Data
KMO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1241,532,134 - 241,595,642 (+)EnsemblGRCh38hg38GRCh38
GRCh381241,531,883 - 241,595,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371241,695,324 - 241,758,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361239,762,330 - 239,825,566 (+)NCBINCBI36hg18NCBI36
Build 341238,021,747 - 238,084,984NCBI
Celera1214,950,683 - 215,013,947 (+)NCBI
Cytogenetic Map1q43NCBI
HuRef1212,153,669 - 212,217,265 (+)NCBIHuRef
CHM1_11242,968,145 - 243,031,623 (+)NCBICHM1_1
Kmo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,459,759 - 175,488,419 (+)NCBIGRCm39mm39
GRCm381175,632,193 - 175,660,853 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,620,381 - 175,662,116 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,562,324 - 177,590,984 (+)NCBIGRCm37mm9NCBIm37
MGSCv361177,468,868 - 177,497,528 (+)NCBImm8
Celera1182,717,886 - 182,746,514 (+)NCBICelera
Cytogenetic Map1H3NCBI
Kmo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01393,684,324 - 93,715,378 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1393,684,437 - 93,716,227 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01398,149,340 - 98,180,255 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41391,363,517 - 91,394,174 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11391,552,400 - 91,583,055 (+)NCBI
Celera1387,155,915 - 87,185,730 (+)NCBICelera
Cytogenetic Map13q25NCBI
Kmo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540610,493,379 - 10,527,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540610,496,102 - 10,527,181 (-)NCBIChiLan1.0ChiLan1.0
KMO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11222,075,577 - 222,138,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,075,268 - 222,138,866 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01217,094,037 - 217,157,827 (+)NCBIMhudiblu_PPA_v0panPan3
KMO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl732,941,487 - 32,994,541 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1732,941,487 - 32,994,541 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Kmo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365268,877,085 - 8,928,280 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KMO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1012,431,982 - 12,490,409 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11012,442,877 - 12,489,417 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21014,879,142 - 14,937,353 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KMO
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl2578,628,757 - 78,670,181 (+)Ensembl
ChlSab1.12578,611,194 - 78,670,314 (+)NCBI
Kmo
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477111,900,020 - 11,942,943 (+)NCBI

Position Markers
D1S547  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,755,937 - 241,756,221UniSTSGRCh37
Build 361239,822,560 - 239,822,844RGDNCBI36
Celera1215,010,922 - 215,011,224RGD
Cytogenetic Map1q42-q44UniSTS
HuRef1212,214,235 - 212,214,537UniSTS
Marshfield Genetic Map1267.51UniSTS
Marshfield Genetic Map1267.51RGD
deCODE Assembly Map1259.16UniSTS
Whitehead-RH Map1932.0UniSTS
Whitehead-YAC Contig Map1 UniSTS
NCBI RH Map11965.8UniSTS
A007K45  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,755,297 - 241,755,561UniSTSGRCh37
Build 361239,821,920 - 239,822,184RGDNCBI36
Celera1215,010,282 - 215,010,546RGD
Cytogenetic Map1q42-q44UniSTS
HuRef1212,213,595 - 212,213,859UniSTS
GeneMap99-GB4 RH Map1750.44UniSTS
NCBI RH Map11966.1UniSTS
SHGC-76600  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,756,984 - 241,757,171UniSTSGRCh37
Build 361239,823,607 - 239,823,794RGDNCBI36
Celera1215,011,987 - 215,012,174RGD
Cytogenetic Map1q43UniSTS
Cytogenetic Map1q42-q44UniSTS
HuRef1212,215,300 - 212,215,487UniSTS
TNG Radiation Hybrid Map1122254.0UniSTS
GeneMap99-GB4 RH Map1750.44UniSTS
NCBI RH Map11965.8UniSTS
D1S3521  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,728,694 - 241,728,842UniSTSGRCh37
Build 361239,795,317 - 239,795,465RGDNCBI36
Celera1214,983,683 - 214,983,831RGD
Cytogenetic Map1q42-q44UniSTS
HuRef1212,187,000 - 212,187,148UniSTS
TNG Radiation Hybrid Map1122208.0UniSTS
GeneMap99-GB4 RH Map1750.44UniSTS
NCBI RH Map11965.8UniSTS
SHGC-105324  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,696,458 - 241,696,746UniSTSGRCh37
Build 361239,763,081 - 239,763,369RGDNCBI36
Celera1214,951,461 - 214,951,749RGD
Cytogenetic Map1q42-q44UniSTS
HuRef1212,154,693 - 212,154,981UniSTS
TNG Radiation Hybrid Map1122196.0UniSTS
SHGC-34194  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,755,440 - 241,755,566UniSTSGRCh37
Build 361239,822,063 - 239,822,189RGDNCBI36
Celera1215,010,425 - 215,010,551RGD
Cytogenetic Map1q42-q44UniSTS
HuRef1212,213,738 - 212,213,864UniSTS
GeneMap99-GB4 RH Map1750.44UniSTS
GeneMap99-GB4 RH Map1753.76UniSTS
Whitehead-RH Map1922.8UniSTS
GeneMap99-G3 RH Map19354.0UniSTS
SHGC-58108  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,751,262 - 241,751,428UniSTSGRCh37
Build 361239,817,885 - 239,818,051RGDNCBI36
Celera1215,006,251 - 215,006,417RGD
Cytogenetic Map1q42-q44UniSTS
HuRef1212,209,570 - 212,209,736UniSTS
TNG Radiation Hybrid Map1122246.0UniSTS
SHGC-76603  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,756,959 - 241,757,182UniSTSGRCh37
Build 361239,823,582 - 239,823,805RGDNCBI36
Celera1215,011,962 - 215,012,185RGD
Cytogenetic Map1q43UniSTS
Cytogenetic Map1q42-q44UniSTS
HuRef1212,215,275 - 212,215,498UniSTS
TNG Radiation Hybrid Map1122254.0UniSTS
GeneMap99-GB4 RH Map1750.44UniSTS
D1S3591  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,756,534 - 241,756,668UniSTSGRCh37
Build 361239,823,157 - 239,823,291RGDNCBI36
Celera1215,011,537 - 215,011,671RGD
Cytogenetic Map1q43UniSTS
Cytogenetic Map1q42-q44UniSTS
HuRef1212,214,850 - 212,214,984UniSTS
TNG Radiation Hybrid Map1122254.0UniSTS
GeneMap99-GB4 RH Map1752.34UniSTS
NCBI RH Map11969.9UniSTS
SHGC-76597  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,758,779 - 241,758,908UniSTSGRCh37
Build 361239,825,402 - 239,825,531RGDNCBI36
Celera1215,013,782 - 215,013,911RGD
Cytogenetic Map1q43UniSTS
Cytogenetic Map1q42-q44UniSTS
HuRef1212,217,095 - 212,217,224UniSTS
TNG Radiation Hybrid Map1122242.0UniSTS
GeneMap99-GB4 RH Map1750.44UniSTS
Whitehead-RH Map1921.2UniSTS
NCBI RH Map11965.8UniSTS
KMO__6342  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371241,758,184 - 241,759,045UniSTSGRCh37
Build 361239,824,807 - 239,825,668RGDNCBI36
Celera1215,013,187 - 215,014,048RGD
HuRef1212,216,500 - 212,217,361UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3202
Count of miRNA genes:1055
Interacting mature miRNAs:1250
Transcripts:ENST00000366555, ENST00000366557, ENST00000366558, ENST00000366559, ENST00000431245, ENST00000477907, ENST00000480967, ENST00000481087, ENST00000484229, ENST00000484628
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 2 1 260 260 165 260 1 14 2 93 9 7 1 1 1
Low 335 608 428 201 1269 176 552 27 751 223 504 839 31 483 255 1
Below cutoff 2027 2235 1020 154 485 22 3374 1813 2846 94 889 693 138 715 2198 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_003679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005273337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005273338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017002649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017002650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF056032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI262990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL133390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU137977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP276365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB989076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB373228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FO393423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000366555   ⟹   ENSP00000355513
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,568,635 - 241,593,459 (+)Ensembl
RefSeq Acc Id: ENST00000366557   ⟹   ENSP00000355515
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,405 - 241,595,642 (+)Ensembl
RefSeq Acc Id: ENST00000366558   ⟹   ENSP00000355516
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,134 - 241,592,288 (+)Ensembl
RefSeq Acc Id: ENST00000366559   ⟹   ENSP00000355517
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,378 - 241,595,642 (+)Ensembl
RefSeq Acc Id: ENST00000431245
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,562,053 - 241,586,736 (+)Ensembl
RefSeq Acc Id: ENST00000477907
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,401 - 241,566,575 (+)Ensembl
RefSeq Acc Id: ENST00000480967
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,369 - 241,562,283 (+)Ensembl
RefSeq Acc Id: ENST00000481087
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,549,662 - 241,555,801 (+)Ensembl
RefSeq Acc Id: ENST00000484229
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,379 - 241,550,087 (+)Ensembl
RefSeq Acc Id: ENST00000484628
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1241,532,338 - 241,562,264 (+)Ensembl
RefSeq Acc Id: NM_003679   ⟹   NP_003670
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,532,378 - 241,595,642 (+)NCBI
GRCh371241,695,324 - 241,758,949 (+)NCBI
Build 361239,762,330 - 239,825,566 (+)NCBI Archive
Celera1214,950,683 - 215,013,947 (+)RGD
HuRef1212,153,669 - 212,217,265 (+)NCBI
CHM1_11242,968,145 - 243,031,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005273337   ⟹   XP_005273394
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,532,024 - 241,592,288 (+)NCBI
GRCh371241,695,324 - 241,758,949 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005273338   ⟹   XP_005273395
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,531,883 - 241,592,288 (+)NCBI
GRCh371241,695,324 - 241,758,949 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017002649   ⟹   XP_016858138
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,531,883 - 241,592,288 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017002650   ⟹   XP_016858139
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,549,800 - 241,592,288 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_003670   ⟸   NM_003679
- UniProtKB: O15229 (UniProtKB/Swiss-Prot),   A8K693 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005273394   ⟸   XM_005273337
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005273395   ⟸   XM_005273338
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016858138   ⟸   XM_017002649
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016858139   ⟸   XM_017002650
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000355517   ⟸   ENST00000366559
RefSeq Acc Id: ENSP00000355513   ⟸   ENST00000366555
RefSeq Acc Id: ENSP00000355515   ⟸   ENST00000366557
RefSeq Acc Id: ENSP00000355516   ⟸   ENST00000366558
Protein Domains
FAD_binding_3

Promoters
RGD ID:6785906
Promoter ID:HG_KWN:8058
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:ENST00000366557,   ENST00000366558,   NM_003679,   UC001HYY.2,   UC009XGO.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361239,761,771 - 239,762,282 (+)MPROMDB
RGD ID:6859396
Promoter ID:EPDNEW_H2863
Type:initiation region
Name:KMO_1
Description:kynurenine 3-monooxygenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2864  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,532,134 - 241,532,194EPDNEW
RGD ID:6859398
Promoter ID:EPDNEW_H2864
Type:multiple initiation site
Name:KMO_2
Description:kynurenine 3-monooxygenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2863  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381241,532,379 - 241,532,439EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q32.3-44(chr1:214023812-248918469)x3 copy number gain See cases [RCV000050981] Chr1:214023812..248918469 [GRCh38]
Chr1:214197155..249212668 [GRCh37]
Chr1:212263778..247179291 [NCBI36]
Chr1:1q32.3-44
pathogenic
GRCh38/hg38 1q41-44(chr1:223347693-248918469)x3 copy number gain See cases [RCV000050581] Chr1:223347693..248918469 [GRCh38]
Chr1:223521035..249212668 [GRCh37]
Chr1:221587658..247179291 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q43(chr1:239631841-242609012)x3 copy number gain See cases [RCV000051587] Chr1:239631841..242609012 [GRCh38]
Chr1:239795141..242772314 [GRCh37]
Chr1:237861764..240838937 [NCBI36]
Chr1:1q43
uncertain significance
GRCh38/hg38 1q43(chr1:240553438-242475553)x3 copy number gain See cases [RCV000051588] Chr1:240553438..242475553 [GRCh38]
Chr1:240716738..242638855 [GRCh37]
Chr1:238783361..240705478 [NCBI36]
Chr1:1q43
uncertain significance
GRCh38/hg38 1q43(chr1:241358731-241676967)x3 copy number gain See cases [RCV000051589] Chr1:241358731..241676967 [GRCh38]
Chr1:241522031..241840269 [GRCh37]
Chr1:239588654..239906892 [NCBI36]
Chr1:1q43
uncertain significance
GRCh38/hg38 1q42.13-44(chr1:230106271-243677283)x1 copy number loss See cases [RCV000051082] Chr1:230106271..243677283 [GRCh38]
Chr1:230242018..243840585 [GRCh37]
Chr1:228308641..241907208 [NCBI36]
Chr1:1q42.13-44
pathogenic
GRCh38/hg38 1q41-44(chr1:221902539-248918469)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051875]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051875]|See cases [RCV000051875] Chr1:221902539..248918469 [GRCh38]
Chr1:222075881..249212668 [GRCh37]
Chr1:220142504..247179291 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q41-44(chr1:223828500-248891309)x3 copy number gain See cases [RCV000051878] Chr1:223828500..248891309 [GRCh38]
Chr1:224016202..249185508 [GRCh37]
Chr1:222082825..247152131 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q41-44(chr1:223887780-248891309)x3 copy number gain See cases [RCV000051880] Chr1:223887780..248891309 [GRCh38]
Chr1:224075482..249185508 [GRCh37]
Chr1:222142105..247152131 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q42.11-44(chr1:224096488-248918469)x3 copy number gain See cases [RCV000051882] Chr1:224096488..248918469 [GRCh38]
Chr1:224284190..249212668 [GRCh37]
Chr1:222350813..247179291 [NCBI36]
Chr1:1q42.11-44
pathogenic
GRCh38/hg38 1q32.2-44(chr1:209646207-248931113)x3 copy number gain See cases [RCV000051861] Chr1:209646207..248931113 [GRCh38]
Chr1:209819552..249225312 [GRCh37]
Chr1:207886175..247191935 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh38/hg38 1q42.3-44(chr1:236237049-248918469)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051883]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051883]|See cases [RCV000051883] Chr1:236237049..248918469 [GRCh38]
Chr1:236400349..249212668 [GRCh37]
Chr1:234466972..247179291 [NCBI36]
Chr1:1q42.3-44
pathogenic
GRCh38/hg38 1q43-44(chr1:239657468-248918610)x3 copy number gain See cases [RCV000051886] Chr1:239657468..248918610 [GRCh38]
Chr1:239820768..249212809 [GRCh37]
Chr1:237887391..247179432 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:240244444-248891309)x3 copy number gain See cases [RCV000051888] Chr1:240244444..248891309 [GRCh38]
Chr1:240407744..249185508 [GRCh37]
Chr1:238474367..247152131 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q42.2-44(chr1:232097468-248918610)x1 copy number loss See cases [RCV000053985] Chr1:232097468..248918610 [GRCh38]
Chr1:232233214..249212809 [GRCh37]
Chr1:230299837..247179432 [NCBI36]
Chr1:1q42.2-44
pathogenic
GRCh38/hg38 1q43-44(chr1:237041745-248918469)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053989]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053989]|See cases [RCV000053989] Chr1:237041745..248918469 [GRCh38]
Chr1:237205045..249212668 [GRCh37]
Chr1:235271668..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:237906379-244022201)x1 copy number loss See cases [RCV000053990] Chr1:237906379..244022201 [GRCh38]
Chr1:238069679..244185503 [GRCh37]
Chr1:236136302..242252126 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:238061020-248918469)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053991]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053991]|See cases [RCV000053991] Chr1:238061020..248918469 [GRCh38]
Chr1:238224320..249212668 [GRCh37]
Chr1:236290943..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:239496961-248918469)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053993]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053993]|See cases [RCV000053993] Chr1:239496961..248918469 [GRCh38]
Chr1:239660261..249212668 [GRCh37]
Chr1:237726884..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:239558430-248918469)x1 copy number loss See cases [RCV000054023] Chr1:239558430..248918469 [GRCh38]
Chr1:239721730..249212668 [GRCh37]
Chr1:237788353..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:239629868-248924593)x1 copy number loss See cases [RCV000054024] Chr1:239629868..248924593 [GRCh38]
Chr1:239793168..249218792 [GRCh37]
Chr1:237859791..247185415 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:241047422-248924593)x1 copy number loss See cases [RCV000054025] Chr1:241047422..248924593 [GRCh38]
Chr1:241210722..249218792 [GRCh37]
Chr1:239277345..247185415 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:241459440-247704671)x1 copy number loss See cases [RCV000054026] Chr1:241459440..247704671 [GRCh38]
Chr1:241622740..247867973 [GRCh37]
Chr1:239689363..245934596 [NCBI36]
Chr1:1q43-44
pathogenic
NM_014322.2(OPN3):c.1198C>T (p.Arg400Cys) single nucleotide variant Malignant melanoma [RCV000064611] Chr1:241594439 [GRCh38]
Chr1:241757741 [GRCh37]
Chr1:239824364 [NCBI36]
Chr1:1q43
not provided
NM_003679.4(KMO):c.958-6412A>G single nucleotide variant Lung cancer [RCV000090702] Chr1:241580267 [GRCh38]
Chr1:241743569 [GRCh37]
Chr1:1q43
uncertain significance
GRCh38/hg38 1q43-44(chr1:238753749-248918467)x1 copy number loss See cases [RCV000134751] Chr1:238753749..248918467 [GRCh38]
Chr1:238917049..249212666 [GRCh37]
Chr1:236983672..247179289 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:238351121-248918469)x1 copy number loss See cases [RCV000134172] Chr1:238351121..248918469 [GRCh38]
Chr1:238514421..249212668 [GRCh37]
Chr1:236581044..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q32.2-44(chr1:209963625-248918469)x3 copy number gain See cases [RCV000134979] Chr1:209963625..248918469 [GRCh38]
Chr1:210136970..249212668 [GRCh37]
Chr1:208203593..247179291 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh38/hg38 1q41-44(chr1:223815147-248918469)x3 copy number gain See cases [RCV000135839] Chr1:223815147..248918469 [GRCh38]
Chr1:224002849..249212668 [GRCh37]
Chr1:222069472..247179291 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q42.13-44(chr1:229022909-248918469)x3 copy number gain See cases [RCV000136666] Chr1:229022909..248918469 [GRCh38]
Chr1:229158656..249212668 [GRCh37]
Chr1:227225279..247179291 [NCBI36]
Chr1:1q42.13-44
pathogenic
GRCh38/hg38 1q43-44(chr1:236556082-248918469)x1 copy number loss See cases [RCV000137554] Chr1:236556082..248918469 [GRCh38]
Chr1:236719382..249212668 [GRCh37]
Chr1:234786005..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:240465122-248918469)x1 copy number loss See cases [RCV000137260] Chr1:240465122..248918469 [GRCh38]
Chr1:240628422..249212668 [GRCh37]
Chr1:238695045..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q42.11-44(chr1:224022862-248918469)x3 copy number gain See cases [RCV000137769] Chr1:224022862..248918469 [GRCh38]
Chr1:224210564..249212668 [GRCh37]
Chr1:222277187..247179291 [NCBI36]
Chr1:1q42.11-44
pathogenic
GRCh38/hg38 1q43-44(chr1:238033575-248924534)x1 copy number loss See cases [RCV000140039] Chr1:238033575..248924534 [GRCh38]
Chr1:238196875..249218733 [GRCh37]
Chr1:236263498..247185356 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43(chr1:239288025-242458053)x1 copy number loss See cases [RCV000141690] Chr1:239288025..242458053 [GRCh38]
Chr1:239451325..242621355 [GRCh37]
Chr1:237517948..240687978 [NCBI36]
Chr1:1q43
pathogenic
GRCh38/hg38 1q42.12-44(chr1:225438480-248787200)x3 copy number gain See cases [RCV000142448] Chr1:225438480..248787200 [GRCh38]
Chr1:225626182..249060210 [GRCh37]
Chr1:223692805..247048022 [NCBI36]
Chr1:1q42.12-44
pathogenic
GRCh38/hg38 1q43-44(chr1:237643281-248918469)x1 copy number loss See cases [RCV000142518] Chr1:237643281..248918469 [GRCh38]
Chr1:237806581..249212668 [GRCh37]
Chr1:235873204..247179291 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q43-44(chr1:238192880-248930485)x1 copy number loss See cases [RCV000143374] Chr1:238192880..248930485 [GRCh38]
Chr1:238356180..249224684 [GRCh37]
Chr1:236422803..247191307 [NCBI36]
Chr1:1q43-44
pathogenic
GRCh38/hg38 1q32.2-44(chr1:207346642-248930485)x3 copy number gain See cases [RCV000143727] Chr1:207346642..248930485 [GRCh38]
Chr1:207519987..249224684 [GRCh37]
Chr1:205586610..247191307 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh37/hg19 1q42.2-44(chr1:234050864-249213059)x3 copy number gain See cases [RCV000240034] Chr1:234050864..249213059 [GRCh37]
Chr1:1q42.2-44
pathogenic
GRCh37/hg19 1q31.3-44(chr1:195483439-249213000)x3 copy number gain See cases [RCV000449172] Chr1:195483439..249213000 [GRCh37]
Chr1:1q31.3-44
pathogenic
GRCh37/hg19 1q42.3-44(chr1:236515525-249224684)x3 copy number gain See cases [RCV000449458] Chr1:236515525..249224684 [GRCh37]
Chr1:1q42.3-44
pathogenic
GRCh37/hg19 1q41-44(chr1:214697099-249224684)x3 copy number gain See cases [RCV000449210] Chr1:214697099..249224684 [GRCh37]
Chr1:1q41-44
pathogenic
GRCh37/hg19 1q43-44(chr1:237233879-249206548)x1 copy number loss See cases [RCV000447669] Chr1:237233879..249206548 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1q43-44(chr1:239781260-249224684)x3 copy number gain See cases [RCV000447584] Chr1:239781260..249224684 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1q42.3-44(chr1:235374095-249224684)x1 copy number loss See cases [RCV000447426] Chr1:235374095..249224684 [GRCh37]
Chr1:1q42.3-44
pathogenic
GRCh37/hg19 1q43-44(chr1:241094652-246670839)x1 copy number loss See cases [RCV000446261] Chr1:241094652..246670839 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1q42.2-44(chr1:231670870-249213000)x3 copy number gain See cases [RCV000447654] Chr1:231670870..249213000 [GRCh37]
Chr1:1q42.2-44
pathogenic
GRCh37/hg19 1q43-44(chr1:241601964-249224684)x1 copy number loss See cases [RCV000448028] Chr1:241601964..249224684 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1q43-44(chr1:240620284-247690417)x1 copy number loss See cases [RCV000512075] Chr1:240620284..247690417 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q42.3-44(chr1:235797384-249224684)x1 copy number loss See cases [RCV000510546] Chr1:235797384..249224684 [GRCh37]
Chr1:1q42.3-44
pathogenic
GRCh37/hg19 1q42.11-44(chr1:224105294-249224684)x3 copy number gain See cases [RCV000510981] Chr1:224105294..249224684 [GRCh37]
Chr1:1q42.11-44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q41-44(chr1:218252551-249224684)x3 copy number gain not provided [RCV000684700] Chr1:218252551..249224684 [GRCh37]
Chr1:1q41-44
pathogenic
GRCh37/hg19 1q42.13-44(chr1:228529973-249181598)x3 copy number gain not provided [RCV000684707] Chr1:228529973..249181598 [GRCh37]
Chr1:1q42.13-44
pathogenic
GRCh37/hg19 1q43(chr1:240958055-243698867)x3 copy number gain not provided [RCV000684715] Chr1:240958055..243698867 [GRCh37]
Chr1:1q43
likely pathogenic
GRCh37/hg19 1q43-44(chr1:241051170-249224684)x1 copy number loss not provided [RCV000684716] Chr1:241051170..249224684 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q42.2-44(chr1:232232335-249218992)x3 copy number gain not provided [RCV000749394] Chr1:232232335..249218992 [GRCh37]
Chr1:1q42.2-44
pathogenic
GRCh37/hg19 1q43-44(chr1:236617216-244515378)x1 copy number loss not provided [RCV000749402] Chr1:236617216..244515378 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1q43(chr1:241646582-241711701)x3 copy number gain not provided [RCV000749412] Chr1:241646582..241711701 [GRCh37]
Chr1:1q43
benign
NM_003679.5(KMO):c.786G>A (p.Pro262=) single nucleotide variant not provided [RCV000951054] Chr1:241566589 [GRCh38]
Chr1:241729889 [GRCh37]
Chr1:1q43
benign
NC_000001.10:g.(?_241661128)_(242034263_?)dup duplication Fumarase deficiency [RCV001033301] Chr1:241661128..242034263 [GRCh37]
Chr1:1q43
uncertain significance
NC_000001.10:g.(?_241661128)_(242034263_?)del deletion Fumarase deficiency [RCV001032378] Chr1:241661128..242034263 [GRCh37]
Chr1:1q43
pathogenic
NC_000001.10:g.(?_241661108)_(242431558_?)del deletion Fumarase deficiency [RCV001032255] Chr1:241661108..242431558 [GRCh37]
Chr1:1q43
pathogenic
NM_003679.5(KMO):c.785C>T (p.Pro262Leu) single nucleotide variant not provided [RCV000920875] Chr1:241566588 [GRCh38]
Chr1:241729888 [GRCh37]
Chr1:1q43
likely benign
GRCh37/hg19 1q43-44(chr1:238669293-249224684)x3 copy number gain not provided [RCV000849904] Chr1:238669293..249224684 [GRCh37]
Chr1:1q43-44
pathogenic
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3 copy number gain not provided [RCV000845852] Chr1:182388773..249111240 [GRCh37]
Chr1:1q25.3-44
pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787399] Chr1:238817623..244138230 [GRCh37]
Chr1:1q43-44
likely pathogenic
GRCh37/hg19 1q42.3-44(chr1:235582580-249224684)x3 copy number gain not provided [RCV000846184] Chr1:235582580..249224684 [GRCh37]
Chr1:1q42.3-44
pathogenic
GRCh37/hg19 1q43(chr1:241499877-241885359)x3 copy number gain not provided [RCV000848301] Chr1:241499877..241885359 [GRCh37]
Chr1:1q43
uncertain significance
Single allele deletion Hereditary leiomyomatosis and renal cell cancer [RCV000850150] Chr1:237244834..242310908 [GRCh37]
Chr1:1q43
pathogenic
GRCh37/hg19 1q43(chr1:241661303-241752434)x3 copy number gain not provided [RCV000846197] Chr1:241661303..241752434 [GRCh37]
Chr1:1q43
uncertain significance
GRCh37/hg19 1q43(chr1:241106058-242088336)x3 copy number gain not provided [RCV000847311] Chr1:241106058..242088336 [GRCh37]
Chr1:1q43
uncertain significance
NM_003679.5(KMO):c.598C>T (p.Pro200Ser) single nucleotide variant not provided [RCV000894979] Chr1:241562315 [GRCh38]
Chr1:241725615 [GRCh37]
Chr1:1q43
benign
NM_003679.5(KMO):c.957+9T>A single nucleotide variant not provided [RCV000953235] Chr1:241568656 [GRCh38]
Chr1:241731956 [GRCh37]
Chr1:1q43
benign
GRCh37/hg19 1q43(chr1:241680265-241929583)x3 copy number gain not provided [RCV001005200] Chr1:241680265..241929583 [GRCh37]
Chr1:1q43
uncertain significance
GRCh37/hg19 1q32.2-44(chr1:210152794-249218992)x3 copy number gain See cases [RCV001194578] Chr1:210152794..249218992 [GRCh37]
Chr1:1q32.2-44
pathogenic
GRCh37/hg19 1q32.1-44(chr1:204045948-249218992)x3 copy number gain See cases [RCV001007407] Chr1:204045948..249218992 [GRCh37]
Chr1:1q32.1-44
pathogenic
GRCh37/hg19 1q43(chr1:241496526-241885359)x3 copy number gain not provided [RCV001259121] Chr1:241496526..241885359 [GRCh37]
Chr1:1q43
likely benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6381 AgrOrtholog
COSMIC KMO COSMIC
Ensembl Genes ENSG00000117009 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000355513 UniProtKB/TrEMBL
  ENSP00000355515 UniProtKB/Swiss-Prot
  ENSP00000355516 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000355517 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000366555 UniProtKB/TrEMBL
  ENST00000366557 UniProtKB/Swiss-Prot
  ENST00000366558 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000366559 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000117009 GTEx
HGNC ID HGNC:6381 ENTREZGENE
Human Proteome Map KMO Human Proteome Map
InterPro FAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kynurenine_monooxygenase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8564 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 8564 ENTREZGENE
OMIM 603538 OMIM
Pfam FAD_binding_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30172 PharmGKB
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Hs.731056 ENTREZGENE
  Hs.744065 ENTREZGENE
UniProt A8K693 ENTREZGENE, UniProtKB/TrEMBL
  H0Y320_HUMAN UniProtKB/TrEMBL
  KMO_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q9BS61_HUMAN UniProtKB/TrEMBL
UniProt Secondary A2A2U8 UniProtKB/Swiss-Prot
  A2A2U9 UniProtKB/Swiss-Prot
  A2A2V0 UniProtKB/Swiss-Prot
  Q5SY07 UniProtKB/Swiss-Prot
  Q5SY08 UniProtKB/Swiss-Prot
  Q5SY09 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-09 KMO  kynurenine 3-monooxygenase    kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)  Symbol and/or name change 5135510 APPROVED