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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737300
Species: Homo sapiens
RGD Object: Gene
Symbol: KMO
Name: kynurenine 3-monooxygenase
Acc ID: CHEBI:18344
Term: kynurenic acid
Definition: A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Chemical ID: MESH:D007736
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KMOmultiple interactionsISOKmo (Rattus norvegicus)6480464CTD[Ro 61-8048 results in decreased activity of KMO protein] which results in increased abundance of Kynurenic AcidPMID:30151725
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