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Gene: RBL2 (RB transcriptional corepressor like 2) Homo sapiens
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Symbol: RBL2
Name: RB transcriptional corepressor like 2
Description: Exhibits promoter-specific chromatin binding activity. Involved in negative regulation of gene expression and regulation of lipid kinase activity. Localizes to the cytosol; nucleolus; and nucleoplasm. Predicted to colocalize with the nucleus; PARTICIPATES IN cell cycle pathway, mitotic; G1/S transition pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 130 kDa retinoblastoma-associated protein; FLJ26459; P130; PRB2; Rb2; RBR-2; retinoblastoma-like 2; retinoblastoma-like protein 2; retinoblastoma-related protein 2
Orthologs:
Mus musculus (house mouse) : Rbl2 (RB transcriptional corepressor like 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rbl2 (RB transcriptional corepressor like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbl2 (RB transcriptional corepressor like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RBL2 (RB transcriptional corepressor like 2)
Canis lupus familiaris (dog) : RBL2 (RB transcriptional corepressor like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbl2 (RB transcriptional corepressor like 2)
Sus scrofa (pig) : RBL2 (RB transcriptional corepressor like 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381653,434,471 - 53,491,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371653,468,351 - 53,525,560 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361652,025,901 - 52,083,061 (+)NCBINCBI36hg18NCBI36
Build 341652,025,900 - 52,083,060NCBI
Celera1637,983,164 - 38,040,371 (+)NCBI
Cytogenetic Map16q12.2NCBI
HuRef1639,355,821 - 39,413,031 (+)NCBIHuRef
CHM1_11654,875,495 - 54,932,695 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RBL2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733260
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.