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Gene: RBL2 (RB transcriptional corepressor like 2) Homo sapiens
Symbol: RBL2
Name: RB transcriptional corepressor like 2
Description: Exhibits promoter-specific chromatin binding activity. Involved in negative regulation of gene expression and regulation of lipid kinase activity. Localizes to the cytosol; nucleolus; and nucleoplasm. Predicted to colocalize with the nucleus; PARTICIPATES IN cell cycle pathway, mitotic; G1/S transition pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 130 kDa retinoblastoma-associated protein; FLJ26459; P130; PRB2; Rb2; RBR-2; retinoblastoma-like 2; retinoblastoma-like protein 2; retinoblastoma-related protein 2
Mus musculus (house mouse) : Rbl2 (RB transcriptional corepressor like 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rbl2 (RB transcriptional corepressor like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbl2 (RB transcriptional corepressor like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RBL2 (RB transcriptional corepressor like 2)
Canis lupus familiaris (dog) : RBL2 (RB transcriptional corepressor like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbl2 (RB transcriptional corepressor like 2)
Sus scrofa (pig) : RBL2 (RB transcriptional corepressor like 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381653,434,471 - 53,491,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371653,468,351 - 53,525,560 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361652,025,901 - 52,083,061 (+)NCBINCBI36hg18NCBI36
Build 341652,025,900 - 52,083,060NCBI
Celera1637,983,164 - 38,040,371 (+)NCBI
Cytogenetic Map16q12.2NCBI
HuRef1639,355,821 - 39,413,031 (+)NCBIHuRef
CHM1_11654,875,495 - 54,932,695 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RBL2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733260
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.