GWAS709323_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS709323_H (intelligence QTL GWAS709323 (human)) Homo sapiens

Symbol: GWAS709323_H
Name: intelligence QTL GWAS709323 (human)
RGD ID: 407060347
Trait: intelligence
LOD Score: Not Available
P Value: 4.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381653,464,743 - 53,464,744RGD_MAPPER_PIPELINEGRCh38
GRCh371653,498,655 - 53,498,656RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS709323_HHumanintelligence  IAGPrs8054299405850206 GWAS_CATALOGPMID:29942086
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
733260RBL2RB transcriptional corepressor like 2165343447153491648Human

Position Markers

Peak: (rs8054299)
Human AssemblyChrPosition (strand)Source
GRCh381653,464,743 - 53,464,744RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407093091GWAS742067_HBMI-adjusted waist-hip ratio QTL GWAS742067 (human)6e-14BMI-adjusted waist-hip ratio165346474353464744Human
407120455GWAS769431_Hcognitive function measurement QTL GWAS769431 (human)9e-21cognitive function measurement165346474353464744Human
407110663GWAS759639_Hcognitive function measurement QTL GWAS759639 (human)7e-17cognitive function measurement165346474353464744Human
407346627GWAS995603_Hattention deficit hyperactivity disorder, autism spectrum disorder, intelligence QTL GWAS995603 (human)1e-15attention deficit hyperactivity disorder, autism spectrum disorder, intelligence165346474353464744Human
407060347GWAS709323_Hintelligence QTL GWAS709323 (human)4e-15intelligence165346474353464744Human
407069032GWAS718008_Hwaist-hip ratio QTL GWAS718008 (human)2e-08waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)165346474353464744Human
407036349GWAS685325_Hcognitive function measurement, self reported educational attainment QTL GWAS685325 (human)2e-16cognitive function measurement, self reported educational attainment165346474353464744Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS685325_H GCST90011875 Cognitive aspects of educational attainment 257,700 European ancestry individuals C 0.304175 2E-16 15.699 rs8054299 0.056602977 cognitive function measurement (EFO:0008354)
self reported educational attainment (EFO:0004784)
 PMID:33414549
GWAS709323_H GCST006250 Intelligence 269,867 European ancestry individuals C NR 4E-15 14.398 rs8054299 7.86 intelligence (EFO:0004337)
 PMID:29942086
GWAS718008_H GCST008997 Waist-hip ratio 381,152 European female individuals C 0.6861 2E-8 7.699 rs8054299 0.0107 waist-hip ratio (EFO:0004343)
 PMID:30239722
GWAS742067_H GCST008994 Waist-to-hip ratio adjusted for BMI 379,501 European ancestry female individuals C 0.6861 6E-14 13.222 rs8054299 0.0146 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30239722
GWAS759639_H GCST006572 Cognitive performance 257,841 European ancestry individuals C 0.6834 7E-17 16.155 rs8054299 0.0256 cognitive function measurement (EFO:0008354)
 PMID:30038396
GWAS769431_H GCST006570 Cognitive performance (MTAG) 402,382 European ancestry individuals C 0.6834 9E-21 20.046 rs8054299 0.023 cognitive function measurement (EFO:0008354)
 PMID:30038396
GWAS995603_H GCST90134330 Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy) 20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements ? NR 1E-15 15 rs8054299 N/A attention deficit hyperactivity disorder (EFO:0003888)
autism spectrum disorder (EFO:0003756)
intelligence (EFO:0004337)
 PMID:35764056
Database Acc Id Source(s)
GWAS Catalog GCST006250 GWAS Catalog

RGD Curation Notes
Note Type Note Reference