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Gene: Rbl2 (RB transcriptional corepressor like 2) Mus musculus
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Symbol: Rbl2
Name: RB transcriptional corepressor like 2
Description: Predicted to have RNA polymerase II activating transcription factor binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; negative regulation of gene expression; and regulation of lipid kinase activity. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including arm; genitourinary system; liver; retina; and spleen. Orthologous to human RBL2 (RB transcriptional corepressor like 2); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 130 kDa retinoblastoma-associated protein; p13; p130; PRB2; Rb; Rb2; RBR-2; retinoblastoma-like 2; retinoblastoma-like protein 2; retinoblastoma-related protein 2
Orthologs:
Homo sapiens (human) : RBL2 (RB transcriptional corepressor like 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rbl2 (RB transcriptional corepressor like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbl2 (RB transcriptional corepressor like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RBL2 (RB transcriptional corepressor like 2)
Canis lupus familiaris (dog) : RBL2 (RB transcriptional corepressor like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbl2 (RB transcriptional corepressor like 2)
Sus scrofa (pig) : RBL2 (RB transcriptional corepressor like 2)
Chlorocebus sabaeus (African green monkey) : RBL2 (RB transcriptional corepressor like 2)
Heterocephalus glaber (naked mole-rat) : Rbl2 (RB transcriptional corepressor like 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl891,070,057 - 91,123,844 (+)EnsemblGRCm38mm10GRCm38
GRCm38891,070,057 - 91,123,844 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37893,593,993 - 93,647,743 (+)NCBIGRCm37mm9NCBIm37
MGSCv36890,825,998 - 90,879,586 (+)NCBImm8
MGSCv36893,960,214 - 94,013,949 (+)NCBImm8
Celera895,389,485 - 95,438,924 (+)NCBICelera
Cytogenetic Map8C4NCBI
cM Map844.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Rbl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11220
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.