GWAS1000859_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1000859_H (BMI-adjusted hip circumference QTL GWAS1000859 (human)) Homo sapiens

Symbol: GWAS1000859_H
Name: BMI-adjusted hip circumference QTL GWAS1000859 (human)
RGD ID: 407351883
Trait: BMI-adjusted hip circumference
Measurement Type: hip circumference   (CMO:0000014)    
LOD Score: Not Available
P Value: 6.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381653,470,031 - 53,470,032RGD_MAPPER_PIPELINEGRCh38
GRCh371653,503,943 - 53,503,944RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1000859_HHumanhip circumference  IAGPrs11540358405850206Based on the EFO term IDGWAS_CATALOGPMID:34021172

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1000859_HHumanBMI-adjusted hip circumference  IAGPrs11540358405850206 GWAS_CATALOGPMID:34021172
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
733260RBL2RB transcriptional corepressor like 2165343447153491648Human

Position Markers

Peak: (rs11540358)
Human AssemblyChrPosition (strand)Source
GRCh381653,470,031 - 53,470,032RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406925240GWAS574216_Happendicular lean mass QTL GWAS574216 (human)6e-10appendicular lean mass165347003153470032Human
407351883GWAS1000859_HBMI-adjusted hip circumference QTL GWAS1000859 (human)6e-18BMI-adjusted hip circumferencehip circumference (CMO:0000014)165347003153470032Human
407353467GWAS1002443_HBMI-adjusted waist-hip ratio QTL GWAS1002443 (human)1e-13BMI-adjusted waist-hip ratio165347003153470032Human
407361834GWAS1010810_HBMI-adjusted waist-hip ratio QTL GWAS1010810 (human)2e-14BMI-adjusted waist-hip ratio165347003153470032Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS574216_H GCST009577 Appendicular lean mass 181,862 European ancestry elderly individuals G 0.30705 6E-10 9.222 rs11540358 0.0467182 appendicular lean mass (EFO:0004980)
 PMID:31761296
GWAS1000859_H GCST012227 Hip circumference adjusted for BMI 186,825 British ancestry men G NR 6E-18 17.222 rs11540358 0.0287043 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
GWAS1002443_H GCST90020027 Waist-hip index 219,872 British ancestry women G NR 1E-13 13 rs11540358 0.0226427 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
GWAS1010810_H GCST90020025 Waist-to-hip ratio adjusted for BMI 219,872 British ancestry women G NR 2E-14 13.699 rs11540358 0.0234029 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
Database Acc Id Source(s)
GWAS Catalog GCST012227 GWAS Catalog

RGD Curation Notes
Note Type Note Reference