Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
altered cardiovascular system homeostasis pathway +   
epinephrine signaling pathway +    
fibrinolysis pathway +    
hematopoiesis pathway +    
hemostasis pathway +    
insulin biosynthetic pathway 
kallikrein-kinin cascade pathway +     
natriuretic peptide signaling pathway +   
natural anticoagulant pathway +    
preproglucagon processing pathway +  
renin-angiotensin cascade pathway +     
The renin-angiotensin cascade (RAS) generates a number of bioactive peptides with diverse physiological and pathophysiological functions. RAS exerts vasoconstriction, vasodilation or vascular remodeling, cell proliferation or anti-proliferation effects, depending on which angiotensin peptide generates the signaling. Some of these features are also shared by the kallikrein-kinin system (KKS); the two systems can interact and cross-talk.

View Interactive Diagram
somatostatin biosynthetic pathway 
thyroglobulin processing pathway +   
thyroid-stimulating hormone biosynthetic pathway 
thyrotropin-releasing hormone biosynthetic pathway 
vascular endothelial growth factor signaling pathway +    
vasopressin signaling pathway +     

Synonyms
Related Synonyms: KEGG:04614 ;   RAS system signaling pathway
Definition Sources: KEGG:ko04614, PMID:12676165, PMID:12793984, PMID:15638741, PMID:15883759, PMID:16816138

paths to the root