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ONTOLOGY REPORT - ANNOTATIONS

Term:multicellular organismal-level iron ion homeostasis
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Accession:GO:0060586 term browser browse the term
Definition:A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
Synonyms:exact_synonym: multicellular organismal iron ion homeostasis


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multicellular organismal-level iron ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK1 ankyrin 1 acts_upstream_of_or_within ISO (PMID:23390527) MGI PMID:23390527 NCBI chr16:23,858,299...23,966,181
Ensembl chr16:23,766,193...23,964,226 		JBrowse link
G B2M beta-2-microglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11113132) Ensembl
MGI		 PMID:11113132 GO_REF:0000107 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BTBD9 BTB domain containing 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22678064) Ensembl
MGI		 PMID:22678064 GO_REF:0000107 NCBI chr12:7,154,805...7,564,050
Ensembl chr12:7,154,925...7,564,017 		JBrowse link
G CYBRD1 cytochrome b reductase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:15,970,873...16,001,296
Ensembl chr36:15,970,946...15,997,983 		JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17932563) Ensembl
MGI		 PMID:17932563 GO_REF:0000107 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22128145) Ensembl
MGI		 PMID:22128145 GO_REF:0000107 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844 		JBrowse link
G EPB42 erythrocyte membrane protein band 4.2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10359562) Ensembl
MGI		 PMID:10359562 GO_REF:0000107 NCBI chr30:10,065,352...10,085,021
Ensembl chr30:10,065,469...10,084,976 		JBrowse link
G FBXL5 F-box and leucine rich repeat protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21907140) Ensembl
MGI		 PMID:21907140 GO_REF:0000107 NCBI chr 3:64,683,770...64,727,161
Ensembl chr 3:64,575,348...64,726,931 		JBrowse link
G FECH ferrochelatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17003376) Ensembl
MGI		 PMID:17003376 GO_REF:0000107 NCBI chr 1:18,352,184...18,384,251
Ensembl chr 1:18,345,811...18,383,092 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16574947), (PMID:20811044), (PMID:22128145), (PMID:23637785), (PMID:24357728)
(PMID:20530874), (PMID:24646470)
(PMID:20113314)
(PMID:24561287)		 Ensembl
MGI		 PMID:16574947 PMID:20113314 PMID:20530874 PMID:20811044 PMID:22128145 More... GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
G HFE homeostatic iron regulator involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15131800)
(PMID:21059897)
(PMID:15914561)
(PMID:10077651)
(PMID:22960056)		 RGD
Ensembl
MGI		 PMID:10077651 PMID:15082582 PMID:15131800 PMID:15914561 PMID:21059897 More... GO_REF:0000107 RGD:1582699 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16075058)
(PMID:19751239), (PMID:24409331)
(PMID:16075058), (PMID:22960056)		 Ensembl
MGI		 PMID:16075058 PMID:19751239 PMID:22960056 PMID:24409331 GO_REF:0000107 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G HMOX1 heme oxygenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (PMID:11092755) MGI PMID:11092755 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290 		JBrowse link
G HYAL2 hyaluronidase 2 acts_upstream_of_or_within ISO (PMID:18772348) MGI PMID:18772348 NCBI chr20:39,029,426...39,034,451
Ensembl chr20:39,031,735...39,034,130 		JBrowse link
G IREB2 iron responsive element binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21907140) Ensembl
MGI		 PMID:21907140 GO_REF:0000107 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G MIR122 microRNA mir-122 acts_upstream_of_or_within ISO (PMID:21364282) MGI PMID:21364282 NCBI chr 1:17,593,858...17,593,915
Ensembl chr 1:17,593,837...17,593,929 		JBrowse link
G MIR17 microRNA mir-17 acts_upstream_of_or_within ISO (PMID:21364282) MGI PMID:21364282 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29624734) Ensembl
MGI		 PMID:29624734 GO_REF:0000107 NCBI chr 9:20,407,296...20,414,094
Ensembl chr 9:20,407,281...20,414,056 		JBrowse link
G NEO1 neogenin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16075058) Ensembl
MGI		 PMID:16075058 GO_REF:0000107 NCBI chr30:36,387,425...36,622,491
Ensembl chr30:36,387,259...36,622,154 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:13,437,819...13,540,167
Ensembl chr21:13,437,925...13,539,616 		JBrowse link
G RHAG Rh associated glycoprotein acts_upstream_of_or_within ISO (PMID:19807729) MGI PMID:19807729 NCBI chr12:17,433,660...17,454,323
Ensembl chr12:17,433,670...17,454,311 		JBrowse link
G RHCE Rh blood group CcEe antigens acts_upstream_of_or_within ISO (PMID:19807729) MGI PMID:19807729 NCBI chr 2:74,466,902...74,503,451
Ensembl chr 2:74,466,928...74,503,448 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19321419)
(PMID:9824471)		 Ensembl
MGI		 PMID:9824471 PMID:19321419 GO_REF:0000107 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18076961), (PMID:5070129) Ensembl
TreeGrafter
MGI		 PMID:5070129 PMID:18076961 GO_REF:0000107 GO_REF:0000118 NCBI chr27:3,788,785...3,823,852
Ensembl chr27:3,787,855...3,822,672 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3039043|PMID:15084469)
(PMID:15342464), (PMID:19596281)		 BHF-UCL
MGI		 PMID:15084469 PMID:15342464 PMID:19596281 MGI:3039043 NCBI chr37:308,054...329,037
Ensembl chr37:303,104...368,865 		JBrowse link
G SOD2 superoxide dismutase 2 acts_upstream_of_or_within ISO (PMID:15205258) MGI PMID:15205258 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G TFR2 transferrin receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22960056) Ensembl
MGI		 PMID:22960056 GO_REF:0000107 NCBI chr 6:9,059,501...9,076,646
Ensembl chr 6:9,060,629...9,076,158 		JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19751239) Ensembl
MGI		 PMID:19751239 GO_REF:0000107 NCBI chr10:27,393,650...27,435,893
Ensembl chr10:27,397,123...27,435,908 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17919
    multicellular organismal process 8092
      multicellular organismal-level homeostasis 936
        multicellular organismal-level chemical homeostasis 80
          multicellular organismal-level iron ion homeostasis 31
Path 2
Term Annotations click to browse term
  biological_process 17919
    homeostatic process 1933
      chemical homeostasis 1182
        monoatomic ion homeostasis 660
          monoatomic cation homeostasis 647
            multicellular organismal-level iron ion homeostasis 31
paths to the root