CYBRD1 (cytochrome b reductase 1) - Rat Genome Database

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Gene: CYBRD1 (cytochrome b reductase 1) Canis lupus familiaris
Analyze
Symbol: CYBRD1
Name: cytochrome b reductase 1
RGD ID: 12084608
Description: ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN response to iron ion (ortholog); PARTICIPATES IN iron uptake pathway; ASSOCIATED WITH COVID-19 (ortholog); split hand-foot malformation 5 (ortholog); FOUND IN apical plasma membrane (inferred); brush border membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13615,970,873 - 16,001,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3615,970,946 - 15,997,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3615,980,919 - 16,011,331 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03616,094,110 - 16,124,607 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3616,094,120 - 16,124,603 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13616,179,767 - 16,210,220 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,179,569 - 16,209,953 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,281,609 - 16,312,312 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CYBRD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13615,970,873 - 16,001,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3615,970,946 - 15,997,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3615,980,919 - 16,011,331 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03616,094,110 - 16,124,607 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3616,094,120 - 16,124,603 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13616,179,767 - 16,210,220 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,179,569 - 16,209,953 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,281,609 - 16,312,312 (+)NCBIUU_Cfam_GSD_1.0
CYBRD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382171,522,233 - 171,558,129 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2171,522,247 - 171,558,129 (+)EnsemblGRCh38hg38GRCh38
GRCh372172,378,743 - 172,414,639 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,087,229 - 172,122,885 (+)NCBINCBI36Build 36hg18NCBI36
Build 342172,204,493 - 172,240,144NCBI
Celera2165,995,455 - 166,031,219 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2164,264,213 - 164,300,158 (+)NCBIHuRef
CHM1_12172,385,534 - 172,421,413 (+)NCBICHM1_1
T2T-CHM13v2.02171,999,382 - 172,035,283 (+)NCBIT2T-CHM13v2.0
Cybrd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39270,948,398 - 70,973,270 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl270,948,267 - 70,973,270 (+)EnsemblGRCm39 Ensembl
GRCm38271,118,054 - 71,142,926 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,117,923 - 71,142,926 (+)EnsemblGRCm38mm10GRCm38
MGSCv37270,956,111 - 70,980,983 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36270,913,320 - 70,943,769 (+)NCBIMGSCv36mm8
Celera272,782,272 - 72,807,772 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map242.38NCBI
Cybrd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8376,342,231 - 76,369,846 (+)NCBIGRCr8
mRatBN7.2355,934,874 - 55,962,132 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl355,934,874 - 55,962,108 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx359,332,726 - 59,359,977 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0367,916,303 - 67,943,578 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0365,678,375 - 65,705,591 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0357,718,496 - 57,745,749 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl357,718,364 - 57,746,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0364,212,933 - 64,240,184 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4353,381,122 - 53,408,375 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1353,277,493 - 53,304,724 (+)NCBI
Celera355,482,564 - 55,509,842 (+)NCBICelera
Cytogenetic Map3q22NCBI
LOC102019452
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554493,368,670 - 3,394,306 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554493,368,976 - 3,394,405 (-)NCBIChiLan1.0ChiLan1.0
LOC100972759
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21374,199,308 - 74,237,028 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B74,214,272 - 74,252,005 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B58,813,554 - 58,849,162 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B176,272,010 - 176,307,618 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B176,272,010 - 176,307,618 (+)Ensemblpanpan1.1panPan2
LOC101976046
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303133,216,918 - 133,245,746 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365091,770,477 - 1,800,619 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365091,770,931 - 1,797,442 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYBRD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1577,649,040 - 77,695,138 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11577,649,124 - 77,695,141 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21587,033,652 - 87,079,560 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYBRD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11057,034,961 - 57,063,560 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1057,035,238 - 57,063,682 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040142,482,438 - 142,510,882 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101701182
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247878,937,620 - 8,964,737 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247878,937,521 - 8,965,279 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CYBRD1
401 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000043428   ⟹   ENSCAFP00000042254
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3615,970,946 - 15,997,983 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845048488   ⟹   ENSCAFP00845038040
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3616,094,120 - 16,124,603 (+)Ensembl
RefSeq Acc Id: XM_038447050   ⟹   XP_038302978
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03616,094,110 - 16,124,607 (+)NCBI
RefSeq Acc Id: XM_038521126   ⟹   XP_038377054
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13616,179,767 - 16,210,220 (+)NCBI
RefSeq Acc Id: XM_038584830   ⟹   XP_038440758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03616,281,609 - 16,312,312 (+)NCBI
RefSeq Acc Id: XM_038649244   ⟹   XP_038505172
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03616,179,569 - 16,209,953 (+)NCBI
RefSeq Acc Id: XM_535960   ⟹   XP_535960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13615,970,873 - 16,001,296 (+)NCBI
Dog10K_Boxer_Tasha3615,980,919 - 16,011,331 (+)NCBI
Sequence:
RefSeq Acc Id: XP_535960   ⟸   XM_535960
- UniProtKB: A0A8C0JQD5 (UniProtKB/TrEMBL),   A0A8C0N0U4 (UniProtKB/TrEMBL),   A0A8I3QDX8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000042254   ⟸   ENSCAFT00000043428
RefSeq Acc Id: XP_038377054   ⟸   XM_038521126
RefSeq Acc Id: XP_038505172   ⟸   XM_038649244
RefSeq Acc Id: XP_038302978   ⟸   XM_038447050
- UniProtKB: A0A8C0JQD5 (UniProtKB/TrEMBL),   A0A8C0N0U4 (UniProtKB/TrEMBL),   A0A8I3QDX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440758   ⟸   XM_038584830
- UniProtKB: A0A8C0JQD5 (UniProtKB/TrEMBL),   A0A8C0N0U4 (UniProtKB/TrEMBL),   A0A8I3QDX8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038040   ⟸   ENSCAFT00845048488
Protein Domains
Cytochrome b561

Promoters
RGD ID:13689071
Promoter ID:EPDNEW_C7138
Type:initiation region
Name:CYBRD1_1
Description:cytochrome b reductase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13615,970,906 - 15,970,966EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012667 Ensembl
  ENSCAFG00000057468 UniProtKB/TrEMBL
  ENSCAFG00030011950 UniProtKB/TrEMBL
  ENSCAFG00040025957 UniProtKB/TrEMBL
  ENSCAFG00845027490 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000103177.1 UniProtKB/TrEMBL
  ENSCAFT00000103586.1 UniProtKB/TrEMBL
  ENSCAFT00030022632.1 UniProtKB/TrEMBL
  ENSCAFT00040048586.1 UniProtKB/TrEMBL
  ENSCAFT00845048488 ENTREZGENE
  ENSCAFT00845048488.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1770 UniProtKB/TrEMBL
InterPro CYB561/CYBRD1-like UniProtKB/TrEMBL
  Cyt_b561/ferric_Rdtase_TM UniProtKB/TrEMBL
NCBI Gene CYBRD1 ENTREZGENE
PANTHER PTHR10106 UniProtKB/TrEMBL
  PTHR10106:SF12 UniProtKB/TrEMBL
Pfam Cytochrom_B561 UniProtKB/TrEMBL
PROSITE CYTOCHROME_B561 UniProtKB/TrEMBL
SMART B561 UniProtKB/TrEMBL
UniProt A0A8C0JQD5 ENTREZGENE
  A0A8C0N0U4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QDX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PQB1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:50286 ENTREZGENE