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ONTOLOGY REPORT - ANNOTATIONS

Term:multicellular organismal-level chemical homeostasis
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Accession:GO:0140962 term browser browse the term
Definition:A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
Synonyms:exact_synonym: multicellular organism level chemical homeostasis;   organismal level chemical homeostasis


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multicellular organismal-level chemical homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2451080 (PMID:27354281)		 Ensembl
RGD		 PMID:27354281 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
multicellular organismal-level iron ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank1 ankyrin 1 acts_upstream_of_or_within ISO MGI:5502651 (PMID:23390527) RGD PMID:23390527 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (PMID:11113132) RGD PMID:11113132 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19252488)
(PMID:26582087), (PMID:28335084), (PMID:32464486)		 UniProt
RGD		 PMID:19252488 PMID:26582087 PMID:28335084 PMID:32464486 GO_REF:0000024 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btbd9 BTB domain containing 9 acts_upstream_of_or_within ISO MGI:4127237 (PMID:22678064) RGD PMID:22678064 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Cybrd1 cytochrome b reductase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30272000)		 UniProt
RGD		 PMID:30272000 GO_REF:0000024 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2679454 (PMID:17932563)		 Ensembl
RGD		 PMID:17932563 GO_REF:0000107 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:109169 (PMID:22128145)		 Ensembl
RGD		 PMID:22128145 GO_REF:0000107 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 acts_upstream_of_or_within ISO MGI:2182816 (PMID:10359562) RGD PMID:10359562 NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932 		JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 acts_upstream_of_or_within ISO MGI:1928268|MGI:5295288 (PMID:21907140) RGD PMID:21907140 NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1858114 (PMID:17003376) RGD PMID:17003376 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12469120)
MGI:3701082|MGI:4351741 (PMID:16574947), (PMID:20113314), (PMID:20530874), (PMID:20811044), (PMID:22128145), (PMID:23637785), (PMID:24357728), (PMID:24561287), (PMID:24646470)
GO_REF:0000107		 RGD
Ensembl		 PMID:12469120 PMID:16574947 PMID:20113314 PMID:20530874 PMID:20811044 More... GO_REF:0000107 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Heph hephaestin involved_in ISS
ISO		 GO_REF:0000024
(PMID:9988272)		 UniProt
RGD		 PMID:9988272 GO_REF:0000024 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hfe homeostatic iron regulator involved_in
acts_upstream_of_or_within		 IEP
IEA
ISO		 GO_REF:0000107
MGI:1934013|MGI:2181388|MGI:2385353|MGI:3775648 (PMID:10077651), (PMID:15131800), (PMID:15914561), (PMID:21059897), (PMID:22960056)
(PMID:21173098)		 Ensembl
RGD		 PMID:10077651 PMID:15131800 PMID:15914561 PMID:21059897 PMID:21173098 More... GO_REF:0000107, RGD:1582699 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hjv hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3587746|MGI:3587747 (PMID:16075058), (PMID:19751239), (PMID:22960056), (PMID:24409331)
UniProtKB:Q92859 (PMID:16075058)		 Ensembl
RGD		 PMID:16075058 PMID:19751239 PMID:22960056 PMID:24409331 GO_REF:0000107 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA		 (PMID:9884342)
GO_REF:0000107		 RGD
Ensembl		 PMID:9884342 GO_REF:0000107 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1857180 (PMID:11092755) RGD PMID:11092755 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3836764 (PMID:18772348)		 Ensembl
RGD		 PMID:18772348 GO_REF:0000107 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Ireb2 iron responsive element binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2152883 (PMID:21907140)		 Ensembl
RGD		 PMID:21907140 GO_REF:0000107 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Mir122 microRNA 122 acts_upstream_of_or_within ISO MGI:2676805 (PMID:21364282) RGD PMID:21364282 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO (PMID:21364282) RGD PMID:21364282 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:29624734) RGD PMID:29624734 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 UniProtKB:Q6ZVN8 (PMID:16075058)
GO_REF:0000107		 RGD
Ensembl		 PMID:16075058 GO_REF:0000107 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:22952941)
GO_REF:0000024		 Ensembl
RGD
Alzheimers_University_of_Toronto		 PMID:22952941 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Rhag Rh-associated glycoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5318589 (PMID:19807729)		 Ensembl
RGD		 PMID:19807729 GO_REF:0000107 NCBI chr 9:20,069,800...20,097,836
Ensembl chr 9:20,069,807...20,097,836 		JBrowse link
G Rhd Rh blood group, D antigen acts_upstream_of_or_within ISO MGI:5318588 (PMID:19807729) RGD PMID:19807729 NCBI chr 5:147,087,479...147,121,716
Ensembl chr 5:147,087,518...147,121,715 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857755|MGI:2446573 (PMID:19321419), (PMID:9824471)		 Ensembl
RGD		 PMID:9824471 PMID:19321419 GO_REF:0000107 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856400 (PMID:18076961), (PMID:5070129)
(PMID:15459009)		 Ensembl
RGD		 PMID:5070129 PMID:15459009 PMID:18076961 GO_REF:0000107 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1889622 (PMID:15342464), (PMID:19596281)
GO_REF:0000107
(PMID:15084469)		 RGD
Ensembl		 PMID:15084469 PMID:15342464 PMID:19596281 GO_REF:0000107 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344 (PMID:15205258) RGD PMID:15205258 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tf transferrin involved_in ISO (PMID:11113131) RGD PMID:11113131 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:21173098)
MGI:2384726 (PMID:22960056)		 RGD PMID:21173098 PMID:22960056 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240) RGD PMID:26642240 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tmprss6 transmembrane serine protease 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:18408718)
MGI:3776631 (PMID:19751239)		 RGD PMID:18408718 PMID:19751239 NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624 		JBrowse link
multicellular organismal-level water homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:17645239)
MGI:1857807 (PMID:12034763)		 RGD PMID:12034763 PMID:17645239 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp4 aquaporin 4 involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:16814974), (PMID:17645239)
(PMID:27751903)
MGI:1857808 (PMID:12034763)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12034763 PMID:16814974 PMID:17645239 PMID:27751903 GO_REF:0000024 GO_REF:0000107 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Avp arginine vasopressin IMP RGD PMID:15231996 RGD:1304346 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bpifa1 BPI fold containing family A, member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24124190)		 UniProt
RGD		 PMID:24124190 GO_REF:0000024 NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19621064)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19621064 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO MGI:108050 (PMID:31365577) RGD PMID:31365577 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (PMID:31365577) RGD PMID:31365577 NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059 		JBrowse link
G Nppa natriuretic peptide A TAS RGD PMID:11751587 RGD:70434 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24124190)		 UniProt
Ensembl
RGD		 PMID:24124190 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
(PMID:17430990), (PMID:28567665)
GO_REF:0000107
(PMID:24124190)		 UniProt
RGD
Ensembl		 PMID:17430990 PMID:24124190 PMID:28567665 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24124190)		 UniProt
Ensembl
RGD		 PMID:24124190 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO
IMP		 (PMID:23136043) RGD PMID:23136043 PMID:23136043 RGD:10400856 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:29357410) RGD PMID:29357410 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
positive regulation of renal water transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:21938401) RGD PMID:21938401 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
renal water absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 acts_upstream_of_or_within ISO MGI:107387|MGI:1314647|MGI:1333777|MGI:1857807 (PMID:10021457), (PMID:10662735), (PMID:10724035), (PMID:10795927), (PMID:11035042), (PMID:12133842), (PMID:15998844), (PMID:16525162), (PMID:9468475) RGD PMID:9468475 PMID:10021457 PMID:10662735 PMID:10724035 PMID:10795927 More... NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103201|MGI:2150021 (PMID:10795927), (PMID:11035042)		 Ensembl
RGD		 PMID:10795927 PMID:11035042 GO_REF:0000107 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Aqp4 aquaporin 4 acts_upstream_of_or_within ISO MGI:103201|MGI:1857808 (PMID:10662735), (PMID:10795927) RGD PMID:10662735 PMID:10795927 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp7 aquaporin 7 acts_upstream_of_or_within ISO MGI:103201 (PMID:15998844) RGD PMID:15998844 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Has2 hyaluronan synthase 2 involved_in IEP PMID:19635555 UniProt PMID:19635555 RGD:8553259 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in IEP PMID:19635555 UniProt PMID:19635555 RGD:8553259 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Mllt6 MLLT6, PHD finger containing acts_upstream_of_or_within ISO MGI:3856248 (PMID:21546577) RGD PMID:21546577 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073 		JBrowse link
G Sctr secretin receptor involved_in ISO (PMID:17283064) RGD PMID:17283064 NCBI chr13:31,127,781...31,190,162
Ensembl chr13:31,127,858...31,180,189 		JBrowse link
renal water homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20466003)		 UniProt
RGD		 PMID:20466003 GO_REF:0000024 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Akap11 A-kinase anchoring protein 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5751858 (PMID:27402760)		 Ensembl
RGD		 PMID:27402760 GO_REF:0000107 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 acts_upstream_of_or_within ISO MGI:2183239 (PMID:16449351) RGD PMID:16449351 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Aqp2 aquaporin 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:27402760)
(PMID:8140421)		 UniProt
RGD		 PMID:8140421 PMID:27402760 GO_REF:0000024 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 acts_upstream_of_or_within ISO MGI:2673510 (PMID:24051376) RGD PMID:24051376 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:15522986) RGD PMID:15522986 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:9817917) RGD PMID:9817917 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
renal water transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:9096382)		 UniProt
GO_Central
RGD		 PMID:9096382 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp2 aquaporin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856830 (PMID:3184310)		 Ensembl
RGD		 PMID:3184310 GO_REF:0000107 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Aqp6 aquaporin 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:8812490)		 UniProt
RGD		 PMID:8812490 GO_REF:0000024 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194 		JBrowse link
surfactant homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within
NOT|acts_upstream_of_or_within		 ISO MGI:3809668 (PMID:18632686)
MGI:3528440 (PMID:18957418)		 RGD PMID:18632686 PMID:18957418 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISO (PMID:17142808), (PMID:17267394), (PMID:17577581), (PMID:28034695) RGD PMID:17142808 PMID:17267394 PMID:17577581 PMID:28034695 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23590306)
MGI:5490511 (PMID:23590306), (PMID:23684610), (PMID:28806758)		 Ensembl
RGD		 PMID:23590306 PMID:23684610 PMID:28806758 GO_REF:0000107 NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968 		JBrowse link
G Bpifa1 BPI fold containing family A, member 1 involved_in ISO
IBA
ISS		 (PMID:23499554)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:23499554 GO_REF:0000024 GO_REF:0000033 (All species) (All species) NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552 		JBrowse link
G Bpifa5 BPI fold containing family A, member 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883 		JBrowse link
G Ctsh cathepsin H involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18216060)		 UniProt
Ensembl
RGD		 PMID:18216060 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2663583 (PMID:12053176)		 Ensembl
RGD		 PMID:12053176 GO_REF:0000107 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IMP RGD PMID:17545485 RGD:2289988 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Fgf7 fibroblast growth factor 7 IMP RGD PMID:11316745 RGD:68696 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO MGI:1926484 (PMID:17641300) RGD PMID:17641300 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671 		JBrowse link
G Kdr kinase insert domain receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12053176)		 Ensembl
RGD		 PMID:12053176 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (PMID:20018880) RGD PMID:20018880 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
G Mbl1 mannose binding lectin 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Napsa napsin A aspartic peptidase involved_in ISO (PMID:18216060) RGD PMID:18216060 NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094 		JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 acts_upstream_of_or_within ISO MGI:1919216 (PMID:25220458) RGD PMID:25220458 NCBI chr15:7,493,531...7,503,758
Ensembl chr15:7,493,531...7,503,854 		JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 acts_upstream_of_or_within ISO MGI:1916971 (PMID:25220458) RGD PMID:25220458 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:29455859) RGD PMID:29455859 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Pla2g4a phospholipase A2 group 4A IMP RGD PMID:10025671 RGD:1642480 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515 (PMID:15162506) RGD PMID:15162506 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Rcn3 reticulocalbin 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:26252542)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26252542 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725 		JBrowse link
G Sftpb surfactant protein B TAS RGD PMID:2920185 RGD:729692 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpd surfactant protein D involved_in IMP
IBA
ISS
ISO
IDA		 GO_REF:0000033
GO_REF:0000024
(PMID:9751757)		 GO_Central
UniProt
RGD		 PMID:9751757 PMID:10666121 PMID:9201966 GO_REF:0000024 GO_REF:0000033, RGD:4144056, RGD:4144058 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857671 (PMID:17641300) RGD PMID:17641300 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO MGI:1931047 (PMID:12053176) RGD PMID:12053176 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
surfactant secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem63a transmembrane protein 63a involved_in IEA
ISO		 GO_REF:0000107
(PMID:38127458)		 Ensembl
RGD		 PMID:38127458 GO_REF:0000107 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183 		JBrowse link
G Tmem63b transmembrane protein 63B involved_in IEA
ISO		 GO_REF:0000107
(PMID:38127458)		 Ensembl
RGD		 PMID:38127458 GO_REF:0000107 NCBI chr 9:15,313,867...15,340,722
Ensembl chr 9:15,320,432...15,340,720 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    multicellular organismal process 8906
      multicellular organismal-level homeostasis 967
        multicellular organismal-level chemical homeostasis 86
          multicellular organismal-level iron ion homeostasis 33
          multicellular organismal-level water homeostasis + 28
          surfactant homeostasis + 27
paths to the root