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ONTOLOGY REPORT - ANNOTATIONS

Term:meiotic cell cycle checkpoint signaling
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Accession:GO:0033313 term browser browse the term
Definition:A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
Synonyms:exact_synonym: meiotic cell cycle checkpoint;   signal transduction involved in meiotic cell cycle checkpoint
 alt_id: GO:0072411


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meiotic cell cycle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsun2 NOP2/Sun RNA methyltransferase 2 involved_in ISO (PMID:23401851) RGD PMID:23401851 NCBI chr 1:33,662,139...33,685,887
Ensembl chr 1:33,662,139...33,685,862 		JBrowse link
meiotic DNA integrity checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hus1 HUS1 checkpoint clamp component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
meiotic recombination checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hormad1 HORMA domain containing 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:21079677), (PMID:21478856)
MGI:5587823 (PMID:22530760)		 UniProt
RGD		 PMID:21079677 PMID:21478856 PMID:22530760 GO_REF:0000024 NCBI chr 2:183,115,815...183,152,383
Ensembl chr 2:183,116,716...183,152,383 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO UniProtKB:P22193 (PMID:9716408) RGD PMID:9716408 NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689 		JBrowse link
G Sycp2 synaptonemal complex protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789 		JBrowse link
G Sycp2l synaptonemal complex protein 2-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:23,589,217...23,645,273
Ensembl chr17:23,592,899...23,648,306 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074 		JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5056148 (PMID:21558374)		 GO_Central
RGD		 PMID:21558374 GO_REF:0000033 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:10935642) RGD PMID:10935642 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
positive regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 involved_in ISO (PMID:35167144) RGD PMID:35167144 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915 		JBrowse link
regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zwint ZW10 interacting kinetochore protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:26486467)		 UniProt
RGD		 PMID:26486467 GO_REF:0000024 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    reproductive process 1909
      meiotic cell cycle process 251
        meiotic cell cycle checkpoint signaling 11
          meiotic DNA integrity checkpoint signaling + 1
          meiotic recombination checkpoint signaling + 5
          meiotic spindle checkpoint signaling + 4
Path 2
Term Annotations click to browse term
  biological_process 20052
    biological regulation 13542
      regulation of biological process 13122
        negative regulation of biological process 5770
          negative regulation of cellular process 5529
            negative regulation of cell cycle 401
              negative regulation of cell cycle process 314
                negative regulation of cell cycle phase transition 264
                  cell cycle checkpoint signaling 186
                    meiotic cell cycle checkpoint signaling 11
                      meiotic DNA integrity checkpoint signaling + 1
                      meiotic recombination checkpoint signaling + 5
                      meiotic spindle checkpoint signaling + 4
paths to the root