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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mitotic cell cycle spindle assembly checkpoint
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Accession:GO:0090266 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.


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regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex C subunit 15 involved_in IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 7:101,530,508...101,551,056
Ensembl chr 7:101,512,922...101,551,056 		JBrowse link
G Anapc15-ps anaphase promoting complex C subunit 15, pseudogene involved_in IBA
ISO		 GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr10:95,508,550...95,509,377
Ensembl chr10:95,508,853...95,509,251 		JBrowse link
G Ccnb1 cyclin B1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnb1-ps cyclin B1, pseudogene involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:41,755,193...41,756,726
Ensembl chr 7:41,755,323...41,756,609 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in IBA
ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:70,135,092...70,328,672
Ensembl chr 4:70,135,093...70,328,680 		JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G Knl1 kinetochore scaffold 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:118,877,600...118,940,978
Ensembl chr 2:118,877,600...118,935,982 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI
GO_Central		 GO_REF:0000008 GO_REF:0000033 NCBI chr 7:122,977,026...123,029,581
Ensembl chr 7:122,969,007...123,029,581 		JBrowse link
G Prpf4b pre-mRNA processing factor 4B involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr13:35,058,803...35,090,047
Ensembl chr13:35,059,285...35,090,047 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in IDA (PMID:21853124) UniProt PMID:21853124 NCBI chr10:93,655,831...93,696,792
Ensembl chr10:93,667,417...93,693,950 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:46,458,311...46,464,477
Ensembl chr17:46,458,313...46,464,479 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113 		JBrowse link
negative regulation of mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr18:74,328,370...74,340,889
Ensembl chr18:74,328,370...74,340,889 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:58,044,016...58,063,748
Ensembl chr14:58,044,018...58,063,642 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in NAS (PMID:17956729) ComplexPortal PMID:17956729 NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in NAS (PMID:17956729) ComplexPortal PMID:17956729 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Cdca8 cell division cycle associated 8 involved_in NAS (PMID:17956729) ComplexPortal PMID:17956729 NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 9:114,517,899...114,552,856
Ensembl chr 9:114,517,858...114,553,370 		JBrowse link
G Gen1 GEN1, Holliday junction 5' flap endonuclease involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr12:11,288,929...11,316,030
Ensembl chr12:11,288,921...11,315,802 		JBrowse link
G Incenp inner centromere protein involved_in NAS (PMID:17956729) ComplexPortal PMID:17956729 NCBI chr19:9,849,659...9,876,853
Ensembl chr19:9,849,660...9,876,915 		JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO
ISS		 GO_Central
UniProt
ComplexPortal		 GO_REF:0000024 GO_REF:0000114 GO_REF:0000119 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 involved_in IMP
ISO		 (PMID:20870947) UniProt
GO_Central
ComplexPortal		 PMID:20870947 GO_REF:0000114 GO_REF:0000119 NCBI chr 6:66,512,205...66,518,091
Ensembl chr 6:66,512,374...66,524,204 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in IMP
ISO		 (PMID:20870947) UniProt
GO_Central		 PMID:20870947 GO_REF:0000119 NCBI chr 8:13,125,476...13,155,343
Ensembl chr 8:13,127,189...13,155,459 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686 		JBrowse link
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18392
      cell cycle process 1387
        regulation of cell cycle process 817
          regulation of mitotic nuclear division 125
            regulation of mitotic cell cycle spindle assembly checkpoint 26
              negative regulation of mitotic spindle assembly checkpoint signaling + 5
              positive regulation of mitotic cell cycle spindle assembly checkpoint + 12
Path 2
Term Annotations click to browse term
  biological_process 28635
    cellular process 18392
      cellular component organization or biogenesis 7407
        cellular component organization 7211
          organelle organization 3739
            organelle fission 535
              nuclear division 476
                mitotic nuclear division 288
                  mitotic sister chromatid segregation 196
                    regulation of mitotic sister chromatid segregation 62
                      negative regulation of mitotic sister chromatid segregation 55
                        negative regulation of mitotic sister chromatid separation 55
                          negative regulation of mitotic metaphase/anaphase transition 55
                            mitotic spindle assembly checkpoint signaling 53
                              regulation of mitotic cell cycle spindle assembly checkpoint 26
                                negative regulation of mitotic spindle assembly checkpoint signaling + 5
                                positive regulation of mitotic cell cycle spindle assembly checkpoint + 12
paths to the root