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Gene: Ska3 (spindle and kinetochore associated complex subunit 3) Mus musculus

Analyze

Symbol:

Ska3

Name:

spindle and kinetochore associated complex subunit 3

RGD ID:

1316255

MGI Page

MGI

Description:

Predicted to enable microtubule binding activity. Involved in establishment of meiotic spindle orientation and spindle assembly involved in female meiosis. Located in meiotic spindle. Is expressed in several structures, including brain; heart ventricle; lung; and vertebral axis musculature. Orthologous to human SKA3 (spindle and kinetochore associated complex subunit 3).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

F630043A04Rik; SKA complex subunit 3; spindle and kinetochore-associated protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	58,044,016 - 58,063,748 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	58,044,018 - 58,063,642 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	57,806,558 - 57,826,291 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	57,806,561 - 57,826,185 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	58,425,398 - 58,445,000 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	56,760,671 - 56,780,273 (-)	NCBI		MGSCv36	mm8
Celera	14	55,603,097 - 55,622,698 (-)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	30.51	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hepatocellular carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-naphthyl isothiocyanate (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

acetamide (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenous acid (EXP)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

carbon nanotube (EXP)

chlorpyrifos (EXP)

chromium(6+) (EXP,ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

DDE (ISO)

diarsenic trioxide (EXP)

Enterolactone (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

hydrogen peroxide (ISO)

lead(0) (ISO)

lidocaine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

menadione (ISO)

methotrexate (ISO)

N-Nitrosopyrrolidine (ISO)

oxaliplatin (ISO)

ozone (EXP)

paracetamol (ISO)

PCB138 (EXP)

perfluorooctanoic acid (ISO)

phenethyl isothiocyanate (ISO)

resveratrol (ISO)

silicon dioxide (EXP,ISO)

sodium arsenite (EXP,ISO)

sunitinib (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

thioacetamide (ISO)

thiram (ISO)

topotecan (ISO)

trovafloxacin (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

attachment of mitotic spindle microtubules to kinetochore (ISO,ISS)

cell division (IEA)

chromosome segregation (IBA)

establishment of meiotic spindle orientation (IMP)

metaphase chromosome alignment (ISO)

mitotic cell cycle (IBA)

mitotic metaphase chromosome alignment (ISS)

mitotic sister chromatid segregation (ISO,ISS)

negative regulation of mitotic spindle assembly checkpoint signaling (ISS)

regulation of microtubule polymerization or depolymerization (ISO,ISS)

spindle assembly involved in female meiosis (IMP)

Cellular Component

centrosome (ISO,ISS)

cytosol (IEA,ISO)

kinetochore (IBA,ISO,ISS,NAS)

meiotic spindle (IDA)

mitotic spindle (ISO,ISS)

outer kinetochore (IBA,ISO,ISS)

SKA complex (IEA)

spindle microtubule (IBA,ISO,ISS)

Molecular Function

microtubule binding (ISO,ISS)

molecular_function (ND)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:12520002	PMID:14610273	PMID:15782199	PMID:16141072	PMID:16141073
PMID:18799693	PMID:19387489	PMID:21267068	PMID:21633384	PMID:21677750	PMID:21873635	PMID:22336914	PMID:22922362	PMID:32554809	PMID:33106477	PMID:34533066

Genomics

Comparative Map Data

Ska3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	58,044,016 - 58,063,748 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	58,044,018 - 58,063,642 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	57,806,558 - 57,826,291 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	57,806,561 - 57,826,185 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	58,425,398 - 58,445,000 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	56,760,671 - 56,780,273 (-)	NCBI		MGSCv36	mm8
Celera	14	55,603,097 - 55,622,698 (-)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	30.51	NCBI

SKA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	21,153,595 - 21,176,552 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	21,153,595 - 21,176,552 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	21,727,734 - 21,750,691 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	20,625,734 - 20,648,710 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	20,625,734 - 20,648,710	NCBI
Celera	13	2,789,717 - 2,812,399 (-)	NCBI		Celera
Cytogenetic Map	13	q12.11	NCBI
HuRef	13	2,529,177 - 2,551,862 (-)	NCBI		HuRef
CHM1_1	13	21,695,750 - 21,718,428 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	20,346,668 - 20,369,632 (-)	NCBI		T2T-CHM13v2.0

Ska3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	36,067,372 - 36,086,563 (-)	NCBI		GRCr8
mRatBN7.2	15	31,951,812 - 31,971,010 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	31,951,825 - 31,971,010 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	33,944,005 - 33,962,337 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	35,094,675 - 35,113,007 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	33,352,759 - 33,371,092 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	38,077,903 - 38,097,100 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	38,077,909 - 38,096,875 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	41,918,694 - 41,937,891 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	36,848,694 - 36,867,026 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	36,864,972 - 36,877,317 (-)	NCBI
Celera	15	31,663,336 - 31,681,669 (-)	NCBI		Celera
Cytogenetic Map	15	p12	NCBI

Ska3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955497	1,875,695 - 1,896,587 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955497	1,874,911 - 1,896,588 (-)	NCBI	ChiLan1.0	ChiLan1.0

SKA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	20,784,341 - 20,818,841 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	11,897,684 - 11,925,841 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	2,481,513 - 2,503,849 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	20,790,236 - 20,812,638 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	20,790,516 - 20,812,554 (-)	Ensembl	panpan1.1		panPan2

SKA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	16,982,174 - 17,011,496 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	16,981,931 - 17,001,803 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	17,078,828 - 17,108,137 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	17,118,457 - 17,147,871 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	17,118,211 - 17,138,178 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	16,993,044 - 17,022,404 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	17,004,451 - 17,033,873 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	17,060,592 - 17,089,963 (+)	NCBI		UU_Cfam_GSD_1.0

Ska3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	119,039,152 - 119,062,514 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936720	586,850 - 605,406 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936720	586,730 - 610,397 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SKA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	1,302,886 - 1,320,981 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	1,302,880 - 1,321,132 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	439,296 - 450,351 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SKA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	32,645 - 57,771 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666057	44,559,055 - 44,584,244 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ska3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624776	16,413,048 - 16,445,892 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624776	16,412,683 - 16,450,784 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ska3
344 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	306
Count of miRNA genes:	240
Interacting mature miRNAs:	258
Transcripts:	ENSMUST00000022536
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357589	Kdnw2_m	kidney weight 2 (mouse)			Not determined		14	20887473	121269804	Mouse
1300625	Cosz2_m	cocaine seizure 2 (mouse)			Not determined		14	35045797	68785736	Mouse
1301777	Bglq15_m	body growth late QTL 15 (mouse)			Not determined		14	42962416	76962593	Mouse
1301489	Lbm10_m	lean body mass 10 (mouse)			Not determined		14	53761296	87761529	Mouse
1357527	Epfpq1_m	epididymal fat percentage QTL 1 (mouse)			Not determined		14	21062450	71885801	Mouse
1301424	Skull21_m	skull morphology 21 (mouse)			Not determined		14	42962416	76962593	Mouse
4142364	Pbwg18_m	postnatal body weight growth 18 (mouse)			Not determined		14	52281984	86282125	Mouse
4141400	Nilac8_m	nicotine induced locomotor activity 8 (mouse)			Not determined		14	43065847	77066045	Mouse
10043889	Cia52_m	collagen induced arthritis QTL 52 (mouse)			Not determined		14	56082381	90082509	Mouse
27226774	Tibl15_m	tibia length 15, 10 week (mouse)					14	30321957	87937436	Mouse
1301562	Hwq1_m	heart weight quantitative locus 1 (mouse)			Not determined		14	56546745	90546941	Mouse
4142485	Modor2_m	modifier of ocular retardation 2 (mouse)			Not determined		14	24926248	58179769	Mouse
4142419	Tgq26_m	triglyceride QTL 26 (mouse)			Not determined			40337319	74337319	Mouse
27226737	Metcl12_m	metatarsal-calcaneal length 12, 10 week (mouse)					14	33221957	59437449	Mouse
1300605	El5_m	epilepsy 5 (mouse)			Not determined		14	49455425	83455556	Mouse
1301091	Bbaa21_m	B.burgdorferi-associated arthritis 21 (mouse)			Not determined		14	43065847	77066045	Mouse
4141484	Hcbip1_m	hexachlorobenzene induced porphyria 1 (mouse)			Not determined			47335250	59962593	Mouse
12880432	Fgf23lq3_m	FGF23 serum level QTL 3 (mouse)					14	53937440	87937440	Mouse
1300998	Cia17_m	collagen induced arthritis 17 (mouse)			Not determined		14	30335250	64335381	Mouse
10043887	Cia50_m	collagen induced arthritis QTL 50 (mouse)			Not determined		14	37430185	71430320	Mouse
1300805	Mors3_m	modifier of obesity related sterility 3 (mouse)			Not determined		14	43037270	77037418	Mouse
10043886	Cia49_m	collagen induced arthritis QTL 49 (mouse)			Not determined		14	29996994	63997133	Mouse
1300909	Ath13_m	atherosclerosis 13 (mouse)			Not determined		14	30335250	64335381	Mouse
13506929	Recrq10_m	recombination rate in male meiosis QTL 10 (mouse)					14	27921957	61137449	Mouse

Markers in Region

AV005697

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	14	57,826,780 - 57,826,923	UniSTS	GRCm38
GRCm38	11	43,463,079 - 43,463,235	UniSTS	GRCm38
MGSCv37	14	58,445,617 - 58,445,760	UniSTS	GRCm37
MGSCv37	11	43,276,581 - 43,276,737	UniSTS	GRCm37
Celera	14	55,623,315 - 55,623,458	UniSTS
Celera	11	48,084,197 - 48,084,352	UniSTS
Cytogenetic Map	14	C3	UniSTS
Cytogenetic Map	11	B1.1	UniSTS
Whitehead/MRC_RH	14	655.32	UniSTS

RH140624

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	14	57,826,750 - 57,826,935	UniSTS	GRCm38
GRCm38	11	43,463,067 - 43,463,266	UniSTS	GRCm38
MGSCv37	14	58,445,587 - 58,445,772	UniSTS	GRCm37
MGSCv37	11	43,276,569 - 43,276,768	UniSTS	GRCm37
Celera	14	55,623,285 - 55,623,470	UniSTS
Celera	11	48,084,185 - 48,084,383	UniSTS
Cytogenetic Map	14	C3	UniSTS
Cytogenetic Map	11	B1.1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001418937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001418938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001418939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_198605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_184859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004938385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119813	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK089223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK138255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK158142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK166171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK199129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK213217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK217625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC117500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC117501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000022536 ⟹ ENSMUSP00000022536

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	58,044,018 - 58,063,620 (-)	Ensembl
GRCm38.p6 Ensembl	14	57,806,561 - 57,826,163 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000223726

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	58,059,593 - 58,063,614 (-)	Ensembl
GRCm38.p6 Ensembl	14	57,822,136 - 57,826,157 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000224108

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	58,044,927 - 58,047,751 (-)	Ensembl
GRCm38.p6 Ensembl	14	57,807,470 - 57,810,294 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000225646

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	58,047,421 - 58,063,642 (-)	Ensembl
GRCm38.p6 Ensembl	14	57,809,964 - 57,826,185 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000225753

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	58,059,344 - 58,063,565 (-)	Ensembl
GRCm38.p6 Ensembl	14	57,821,887 - 57,826,108 (-)	Ensembl

RefSeq Acc Id:

NM_001418937 ⟹ NP_001405866

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	58,044,017 - 58,063,627 (-)	NCBI

RefSeq Acc Id:

NM_001418938 ⟹ NP_001405867

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	58,044,017 - 58,063,627 (-)	NCBI

RefSeq Acc Id:

NM_001418939 ⟹ NP_001405868

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	58,044,017 - 58,063,627 (-)	NCBI

RefSeq Acc Id:

NM_198605 ⟹ NP_941007

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	58,044,017 - 58,063,627 (-)	NCBI
GRCm38	14	57,806,561 - 57,826,163 (-)	NCBI
MGSCv37	14	58,425,398 - 58,445,000 (-)	RGD
Celera	14	55,603,097 - 55,622,698 (-)	RGD
cM Map	14		ENTREZGENE

Sequence:

show sequence

GCGTTCGTTCGAGGGGACTGGAGGTCAGCAGTCGGCTCGGCGGCCCTCAGCATGAACCCCATCC
AGAGTTTCCACTGTAAGCTGCGGGGTCTGGCCACCACGCTGGACAGCGAGACGGCCCGGCTGCT
GAGAGCGCTGGACGGCGAGGACAGCGACTTTGAAGATTCTCCAGGGAGAATTTTGCATGACCTT
CATTCAGAAGTCCAGACTCTAAAGGATAATGTTAATGCTCTTCTCGATGAAGCAAGATTGGAGA
ACCAAGAAAGCACAAGGTTCAAAAAGGCAACAAAAATACTGATGGAAAAAAACTCAGCAGACGT
CAGAAAACTAAGAGAGTTTTTCCAGAAGTATGGCTACCAAGCGCGTGACAAGGAGGATTCAGGC
TGTGAGCACAGAGTGAACAACTCCACCCCAGAGTTAGCTGTGTGTAAAGACATTCAAAAGGCCG
GTGTGAAGGAGCTGTCTGATCCCTGTGTTCCGAGCGGTTCTGTTTCTGAAGAGCCTCTGCGAAG
CCCACAGCTCTCAGACTTTGGACTTCAGCGGTACATAATTTCCCAAGTCCCAGCCAACCCTCCC
CAGACAGCTGCCAGCCTCAAAGAAGAACGTGTAGCTGAGACCCCTCCTGCCAAAGACCCCTCTG
TTCAAGTGCTGAAGACCCCGCGGTGTGCTCTAAGGATGGATGATTTTGAGTGTGAAACTCCTAA
ATTAGAACACTTTGGTATATCTGAACATACTATGTGTTTAAATGAAGATTACACAATGGGACTT
AAAAATATGAAGAACATTAAAAGTTCCCTTTTGAGTGGTGTCAGTGGAGAAGCCATAGGAACTG
GGCCTGTGACCAGTGATAATTCTTTTGCCATTCCTGGTCCCATAATCCAGCAGATGGAAGAAAA
CGATGTGGAATACGTAAGTTCACCATTGCCACCTAAATTCTGCACTCCTGGTTTGAAAATTCCT
TCTACAATGGACAGAACAGATTTGGTATCTATAGATTATCCACTATCAAAGCCAAATAGTTCAT
CAACTGATTTGGAAATTAAAGATTGTGTTCCGTTAATTTTAAATTCAGATGAATGCTATCAGAG
TTTTGCAGAGCCCCCTTCTTCAGCAATTACTTCTTGTGAAAATTTTGCAACACCATCTCCTCCG
AAAGTTACTGCGATTCCAGAAGACATTCTCCAGATGATAACAAAGCACAGCTCAAACCTAGCTT
CTCCCTTGGATGTTAAAGTGATGCCACGGAGGAAGGGCACCCGAGGCGCTGCCAACAAGGAAAA
CTGGTAACGGAATTCTACAGTGGATACATCCAATACAGAAGCTAGACAGAACAGGAAAGTGAGC
TGGACTAAGGTTCTCAGGATTATAACTGGTTAGCACAGACCAGTAGAAGTGGAGAGAGGGCTCC
TGCTGGCAGTCAGTCTTCTTTCTCCCAGTCTCTCTTATTTCATTCTTACGGGAATGTTTCCGTT
TCACCGCACTGTGGTGGCCTTTCCAGCTTGACCACCCAGCAGATCCCGATTCTACCTGGAAGAT
TCTGAACACCTACTCTGAGCCAGAAGCCTTGGGAACGTCTTGATTCTGGAACTATCTAATGGCC
TTTGAGCCCAAGATCCTTCTGATCCAAGAACAGTTAGAAAGTAATTCTCCAAGTTCATGACAGT
GCTACTTGGGAGAGCTTTGTGCTGCAGCCAGGTAGGGAATGAGGAGCTGGTGTTCTGAAGAGTC
CAGCTACAATTTTGAGAAATAATTGGCAAATACCAGTTGACTGACTAGTTTTGGGAATTTCTTT
CTCCCAATACAGGGTTTCTCTGTGTAGCTGTGGCAGTCCTGAAACTTACTCTGTAGACCAGGCT
AGATCCTCCTGTCTCTGCCTCTTGAGTAGAAATTAAAGATGTGTACCACCACCGTCTGGCAGCT
TTAGGAAATTTTGTGTGGCATAAAGATTATTCTAATTGTGCATTGAAAATCAAGTGGAGAGCTA
GAGAGATGGCTCAGTGGTTAAGAGCACTGACTGTTCTTCCAGAGGTCCTGAGTTCAATTCCCAG
CAACCACATGGTGGTAACAACCATCTGTAATGGGATCCGTTGCCCTCTTCTGGCGTGTCTAAAG
ACCGCTACAATGTACTCATCTACATAAATAATTCTGTTTAAAAAAAAATCAAGTGGAAAAATTC
CAGGATAATACTAATAAGTGCTTGTATTTTTTGTTGTTGTTGTTATTGTACATAATGTAAAATA
AATGATTTTCTGAGTAGCCC

hide sequence

RefSeq Acc Id:

NR_184859

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	58,044,017 - 58,063,627 (-)	NCBI

RefSeq Acc Id:

XR_004938385

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	58,044,016 - 58,063,748 (-)	NCBI

Sequence:

show sequence

CCTCGGCGCTCCGCGTCCCCCGACCGATGCGGCGGCGCGCTGCTTCCGGTCTCTCTGGGGCCCT
GATGCTAGAGTTCCGCTCTCGCGAGAGACGCCTTCTGCGCCTGCGCAGGATTCAAATGTGTAGC
GCGTTCGTTCGAGGGGACTGGAGGTCAGCAGTCGGCTCGGCGGCCCTCAGCATGAACCCCATCC
AGAGTTTCCACTGTAAGCTGCGGGGTCTGGCCACCACGCTGGACAGCGAGACGGCCCGGCTGCT
GAGAGCGCTGGACGGCGAGGACAGCGACTTTGAAGATTCTCCAGGGAGAATTTTGCATGACCTT
CATTCAGAAGTCCAGACTCTAAAGGATAATGTTAATGCTCTTCTCGATGAAGCAAGATTGGAGA
ACCAAGAAAGCACAAGGTTCAAAAAGGCAACAAAAATACTGATGGAAAAAAACTCAGCAGACGT
CAGAAAACTAAGAGAGTTTTTCCAGAAGTATGGCTACCAAGCGCGTGACAAGGAGGATTCAGGC
TGTGAGCACAGAGTGAACAACTCCACCCCAGAGTTAGCTGTGTGTAAAGACATTCAAAAGGCCG
GTGTGAAGGAGCTGTCTGATCCCTGTGTTCCGAGCGGTTCTGTTTCTGAAGAGCCTCTGCGAAG
CCCACAGCTCTCAGACTTTGGACTTCAGCGGTACATAATTTCCCAAGTCCCAGCCAACCCTCCC
CAGACAGCTGCCAGCCTCAAAGAAGAACGTGTAGCTGAGACCCCTCCTGCCAAAGACCCCTCTG
TTCAAGTGCTGAAGACCCCGCGGTGTGCTCTAAGGATGGATGATTTTGAGTGTGAAACTCCTAA
ATTAGAACACTTTGGTATATCTGAACATACTATGTGTTTAAATGAAGATTACACAATGGGACTT
AAAAATATGAAGAACATTAAAAGTTCCCTTTTGAGTGGTGTCAGTGGAGAAGCCATAGGAACTG
GGCCTGTGACCAGTGATAATTCTTTTGCCATTCCTGGTCCCATAATCCAGCAGATGGAAGAAAA
CGATGTGGAATACGTAAGTTCACCATTGCCACCTAAATTCTGCACTCCTGGTTTGAAAATTCCT
TCTACAATGGACAGAACAGATTTGATGAATGCTATCAGAGTTTTGCAGAGCCCCCTTCTTCAGC
AATTACTTCTTGTGAAAATTTTGCAACACCATCTCCTCCGAAAGTTACTGCGATTCCAGAAGAC
ATTCTCCAGGTCATTTTCTAGGTTTTTTTTTTCCTAATATTTTCAAAATTATATATCTGTGTTA
GAAAACTGCAATCGCATATAAACTGTCATATTTGCCATCATGCTTTGGGTATTGAGAAAAACCT
TAAGGCTTTCCTGAACCAGTCAGAAGTTTCTAACTTGGTGTTAGTAATATTACTCTCCTGGGGT
ACTTTGTCTTGTAGCTTGTTCTACAGTGTATTGTTTCTGTTAGTTTTTAATCTGTAGTTGCTAT
ATTAGCTATCGTCCAATTAAAAGTGGGAGTGTCCTTTGCCCTATAATTCTCCATAGCAAGGTCT
CATTAATAACACGTGCCTGCATTTCTCAAACTGTCAGTGTGCAGGCACATAGCATTGATTCACA
TAGTATTAAAATATTTGACTGTGGAGTATGGCACCACCAGCTAGTAGACACTACAAGAGGACTA
GTCTGACTCTAGTCTGCTTTATAGTGTTGAGCAGTTAGTGCTGGGGTGCAGCGAAGTCCTGTGT
GACTGGGGTGCCATGAGAGCAGTAAACTGTGAGACATCTATTTTTAATTGTGTGTATATTGTGG
GTGTGTAGGTGTGTACCTTTGAATGCAGGTGCCTGAGTAGTCAGAAGAGGGAGGCAGAGCTAGC
GTTAGAGGCAATAGTAAGCTGTCCAAAGTCGGAGCTGGGAACTGAACTCTGGTCCTCTGTAAGA
GCTTAACTGCTATCTCCAGTCCCACCACCTGACTGCTTGCTTTCTTAGAGGAGAAAGTAGGTAA
GGAGCCACCTGATTTATGAGCACATGTGGGGGTTACTACTTCCTGCTGGAGGGCTTCTTCCTAT
GAGGGTACGGAAACCTTGTCTTTGTCTTAGTGGTTGCTTCTTTTTAGGGGTGAAACACTGGGGC
TTGTGTATGGTATAGAAGCACTTGGCCACTTTGTCACCTGCCCAGTCCCAGGGACACCTTACAC
TCAGTGTGCTCCTTCCAGTTTTTCCTTTCCATGTTTTAATTGTGTAAGTTTATTATACATGGTA
ATGTGTTATTATTATTATTATACATGGTAATGGTTTTCATGGTGACATTTTCATATATGTACAT
AATATATTCATGTTTACAGATATATGCAAACACCCATTTCCTTCTCTTGTTTCGCTATTGCAGA
TCTCCTTCCCCTTCCCAACAGCGCCCTCTGTCTTTATGTTGAGAGAGACTCTGAAGGAGAGATG
AGCATGACTGAGGGCTTGTTTATGAGTGGCTATGCCACTGGCGTCAGGGCTTCACTCTCATTCA
CTGTGTCTCGGTTCCCAAGGAAGAGCTGGGGCCTGTGAGCCTCCCCGTCCATGAGGGTGCTCAC
TTGCTGTCTACAGTGCACAGACTCACAGCTGCTGCATATATTCTCTTCAGTGCATTGGGGAGTC
TTCCTGTCTTTTTTTTTTTTTTTTTTTTTCATCCTCATCAAGACTTAACATGGCTCTCGGGATA
TTTCCATTAACTTCAGTAAATGTGTCTTTAGACTTTAGACATCAAACTTCCATATGAAGTTAAA
ATCTTATATATTTTTTTTACTATTCAATGTCTGTGTGAATTGCTGTTGTTTGTTTTTGTTTTTT
TGTTTTTTCGAGACAGGGTTTCTCTGTATAACCCTGGCTGTCCTGGAACTCACTCTGTAGACCA
GGCTGGCCTCAAACTCAGAAATCCGCCTGCCTCTGCCTCCCGAGTGCTGGGATTAAAGGCGTGC
GCCACCATGCCCAGCTTGTTTTGTTTTGTTTTGTTTTTAAGTATTGTAAGTAACCCTTAAGTTC
ATGGCTTTTCTTGAATGTTTCTAACACCTTGCCTATTTGTCATTGACATGACCTGATAAAAAGA
AATGTGTTTTGTTTTAGATGATAACAAAGCACAGCTCAAACCTAGCTTCTCCCTTGGATGTTAA
AGTGATGCCACGGAGGAAGGGCACCCGAGGCGCTGCCAACAAGGAAAACTGGTAACGGAATTCT
ACAGTGGATACATCCAATACAGAAGCTAGACAGAACAGGAAAGTGAGCTGGACTAAGGTTCTCA
GGATTATAACTGGTTAGCACAGACCAGTAGAAGTGGAGAGAGGGCTCCTGCTGGCAGTCAGTCT
TCTTTCTCCCAGTCTCTCTTATTTCATTCTTACGGGAATGTTTCCGTTTCACCGCACTGTGGTG
GCCTTTCCAGCTTGACCACCCAGCAGATCCCGATTCTACCTGGAAGATTCTGAACACCTACTCT
GAGCCAGAAGCCTTGGGAACGTCTTGATTCTGGAACTATCTAATGGCCTTTGAGCCCAAGATCC
TTCTGATCCAAGAACAGTTAGAAAGTAATTCTCCAAGTTCATGACAGTGCTACTTGGGAGAGCT
TTGTGCTGCAGCCAGGTAGGGAATGAGGAGCTGGTGTTCTGAAGAGTCCAGCTACAATTTTGAG
AAATAATTGGCAAATACCAGTTGACTGACTAGTTTTGGGAATTTCTTTCTCCCAATACAGGGTT
TCTCTGTGTAGCTGTGGCAGTCCTGAAACTTACTCTGTAGACCAGGCTAGATCCTCCTGTCTCT
GCCTCTTGAGTAGAAATTAAAGATGTGTACCACCACCGTCTGGCAGCTTTAGGAAATTTTGTGT
GGCATAAAGATTATTCTAATTGTGCATTGAAAATCAAGTGGAGAGCTAGAGAGATGGCTCAGTG
GTTAAGAGCACTGACTGTTCTTCCAGAGGTCCTGAGTTCAATTCCCAGCAACCACATGGTGGTA
ACAACCATCTGTAATGGGATCCGTTGCCCTCTTCTGGCGTGTCTAAAGACCGCTACAATGTACT
CATCTACATAAATAATTCTGTTTAAAAAAAAATCAAGTGGAAAAATTCCAGGATAATACTAATA
AGTGCTTGTATTTTTTGTTGTTGTTGTTATTGTACATAATGTAAAATAAATGATTTTCTGAGTA
GCCCAC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001405866	(Get FASTA)	NCBI Sequence Viewer
	NP_001405867	(Get FASTA)	NCBI Sequence Viewer
	NP_001405868	(Get FASTA)	NCBI Sequence Viewer
	NP_941007	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI17501	(Get FASTA)	NCBI Sequence Viewer
	AAI17502	(Get FASTA)	NCBI Sequence Viewer
	BAC40798	(Get FASTA)	NCBI Sequence Viewer
	EDL36162	(Get FASTA)	NCBI Sequence Viewer
	EDL36163	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000022536
	ENSMUSP00000022536.3
GenBank Protein	Q8C263	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_941007 ⟸ NM_198605
- Peptide Label:	isoform 1
- UniProtKB:	Q149T5 (UniProtKB/Swiss-Prot), Q149T6 (UniProtKB/Swiss-Prot), Q8C263 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNPIQSFHCKLRGLATTLDSETARLLRALDGEDSDFEDSPGRILHDLHSEVQTLKDNVNALLDE ARLENQESTRFKKATKILMEKNSADVRKLREFFQKYGYQARDKEDSGCEHRVNNSTPELAVCKD IQKAGVKELSDPCVPSGSVSEEPLRSPQLSDFGLQRYIISQVPANPPQTAASLKEERVAETPPA KDPSVQVLKTPRCALRMDDFECETPKLEHFGISEHTMCLNEDYTMGLKNMKNIKSSLLSGVSGE AIGTGPVTSDNSFAIPGPIIQQMEENDVEYVSSPLPPKFCTPGLKIPSTMDRTDLVSIDYPLSK PNSSSTDLEIKDCVPLILNSDECYQSFAEPPSSAITSCENFATPSPPKVTAIPEDILQMITKHS SNLASPLDVKVMPRRKGTRGAANKENW hide sequence

Ensembl Acc Id:

ENSMUSP00000022536 ⟸ ENSMUST00000022536

RefSeq Acc Id:	NP_001405868 ⟸ NM_001418939
- Peptide Label:	isoform 3

RefSeq Acc Id:	NP_001405866 ⟸ NM_001418937
- Peptide Label:	isoform 2

RefSeq Acc Id:	NP_001405867 ⟸ NM_001418938
- Peptide Label:	isoform 3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8C263-F1-model_v2	AlphaFold	Q8C263	1-411	view protein structure

Promoters

RGD ID:

8682568

Promoter ID:

EPDNEW_M19314

Type:

multiple initiation site

Name:

Ska3_1

Description:

Mus musculus spindle and kinetochore associated complex subunit3 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	14	57,826,168 - 57,826,228	EPDNEW

RGD ID:

6825205

Promoter ID:

MM_KWN:17069

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

NM_026401, NM_198605

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	14	58,444,869 - 58,445,369 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3041235	AgrOrtholog
Ensembl Genes	ENSMUSG00000021965	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000022536	ENTREZGENE
	ENSMUST00000022536.3	UniProtKB/Swiss-Prot
Gene3D-CATH	6.10.250.1400	UniProtKB/Swiss-Prot
InterPro	SKA3	UniProtKB/Swiss-Prot
KEGG Report	mmu:219114	UniProtKB/Swiss-Prot
MGD	MGI:3041235	ENTREZGENE
NCBI Gene	219114	ENTREZGENE
PANTHER	PTHR48118	UniProtKB/Swiss-Prot
	SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3	UniProtKB/Swiss-Prot
PhenoGen	Ska3	PhenoGen
UniProt	Q149T5	ENTREZGENE
	Q149T6	ENTREZGENE
	Q8C263	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q149T5	UniProtKB/Swiss-Prot
	Q149T6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-07-31	Ska3	spindle and kinetochore associated complex subunit 3	F630043A04Rik	RIKEN cDNA F630043A04 gene	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD