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ONTOLOGY REPORT - ANNOTATIONS


Term:demethylation
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Accession:GO:0070988 term browser browse the term
Definition:The process of removing one or more methyl groups from a molecule.



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demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh4 alkB homolog 4, lysine demethylase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:20,524,030...20,529,947
Ensembl chr12:20,524,030...20,529,947
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
JBrowse link
G Kdm3a lysine demethylase 3A involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kdm3b lysine demethylase 3B involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628
JBrowse link
G Mmachc metabolism of cobalamin associated C involved_in ISO (PMID:19801555) RGD PMID:19801555 NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601
JBrowse link
G Por cytochrome p450 oxidoreductase IDA positive regulation of N-demethylation by cytochrome P450 2B4 RGD PMID:19171935 RGD:4889812 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
oxidative demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA
(PMID:18619574)
GO_REF:0000107
RGD
Ensembl
PMID:18619574 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO
IMP
(PMID:15039299), (PMID:19438707) RGD PMID:15039299 PMID:19438707 PMID:19059219 RGD:401901280 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IDA
ISO
IBA
(PMID:15039299), (PMID:18619574)
GO_REF:0000033
RGD
GO_Central
PMID:15039299 PMID:18619574 PMID:12971802 GO_REF:0000033, RGD:5129544 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12971802 GO_REF:0000033, RGD:5129544 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO
IBA
(PMID:15039299)
GO_REF:0000033
RGD
GO_Central
PMID:15039299 GO_REF:0000033 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
oxidative RNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO
IBA
(PMID:31188562)
GO_REF:0000033
RGD
GO_Central
PMID:31188562 GO_REF:0000033 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24360279)
UniProt
Ensembl
RGD
PMID:24360279 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
protein demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Phf2 PHD finger protein 2 involved_in ISO (PMID:21532585) RGD PMID:21532585 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208
JBrowse link
G Ppme1 protein phosphatase methylesterase 1 involved_in ISO (PMID:10318862) RGD PMID:10318862 NCBI chr 1:154,668,099...154,715,079
Ensembl chr 1:154,668,109...154,715,110
JBrowse link
G Riox1 ribosomal oxygenase 1 involved_in ISO (PMID:35210392) RGD PMID:35210392 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        demethylation 20
          oxidative demethylation + 10
          protein demethylation + 4
paths to the root