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ONTOLOGY REPORT - ANNOTATIONS

Term:acetylcholine-gated monoatomic cation-selective channel activity
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Accession:GO:0022848 term browser browse the term
Definition:Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
Synonyms:exact_synonym: acetylcholine-activated cation-selective channel activity;   acetylcholine-gated cation channel activity;   ionotropic acetylcholine receptor activity;   nAChR;   nicotinergic acetylcholine receptor activity;   nicotinic acetylcholine-activated cation-selective channel activity
 broad_synonym: acetylcholine-gated cation-selective channel activity
 alt_id: GO:0004889;   GO:0016904


show annotations for term's descendants           Sort by:
acetylcholine-gated monoatomic cation-selective channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit enables
contributes_to		 IDA
ISO
IBA		 (PMID:9221765)
GO_REF:0000033
MGI:87890|MGI:87893|MGI:87894|MGI:87895 (PMID:2383398)		 RGD
GO_Central		 PMID:2383398 PMID:9221765 PMID:1702709 PMID:22461452 GO_REF:0000033, RGD:68734, RGD:8549758 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit enables IBA
ISO		 GO_REF:0000033
MGI:3774038 (PMID:18077337)		 GO_Central
RGD		 PMID:18077337 GO_REF:0000033 NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit enables IDA
ISO
IBA		 (PMID:8906617)
GO_REF:0000033		 RGD
GO_Central		 PMID:8906617 PMID:2832952 GO_REF:0000033, RGD:728252 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit enables IMP
IEA
ISO
IGI
IBA		 GO_REF:0000107
(PMID:8906617)
PMID:21540349
GO_REF:0000002
GO_REF:0000033
MGI:2155602 (PMID:11923417)		 Ensembl
RGD
InterPro
GO_Central		 PMID:8906617 PMID:11923417 PMID:11297818 PMID:21540349 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1643016, RGD:12790638 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit enables IDA
IC
IMP
IEA
ISO
IBA		 GO_REF:0000002
(PMID:8906617)
GO_REF:0000107
GO_REF:0000033
MGI:1926251|MGI:3511287|MGI:87891 (PMID:11222635), (PMID:12130686), (PMID:15528443), (PMID:15569257), (PMID:15741168)		 InterPro
RGD
Ensembl
GO_Central		 PMID:8906617 PMID:11222635 PMID:12130686 PMID:15528443 PMID:15569257 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:727641, RGD:2303190, RGD:8549520 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit enables IMP
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:12814364 PMID:11297818 GO_REF:0000002 GO_REF:0000033, RGD:1298760, RGD:1643016 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit enables IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
MGI:2179133 (PMID:11850448)		 Ensembl
GO_Central
RGD		 PMID:11850448 GO_REF:0000033 GO_REF:0000107 NCBI chr16:64,697,741...64,704,441
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit enables IDA
IMP
IEA
ISO
IBA		 GO_REF:0000002
GO_REF:0000107
PMID:21540349
(PMID:12508119), (PMID:18387948), (PMID:21718690), (PMID:8145738), (PMID:8906617)
PMID:11222635
PMID:15760934
GO_REF:0000033
MGI:1888407 (PMID:11834293), (PMID:9037516), (PMID:9364063), (PMID:9495872)		 InterPro
Ensembl
RGD
GO_Central		 PMID:8145738 PMID:8906617 PMID:9037516 PMID:9364063 PMID:9495872 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:727702, RGD:1600971, RGD:1643016, RGD:8549520, RGD:12790638, RGD:8554133, RGD:8554382 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit enables IDA
ISO
IEA
IBA		 (PMID:25282151)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
MGI:2158742 (PMID:18077337)		 RGD
InterPro
Ensembl
GO_Central		 PMID:18077337 PMID:25282151 PMID:7954834 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:728400 NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit enables
contributes_to		 IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
MGI:87885|MGI:87893|MGI:87894|MGI:87895 (PMID:2383398)
MGI:87893|MGI:87895 (PMID:8798466)		 InterPro
Ensembl
GO_Central
RGD		 PMID:2383398 PMID:8798466 PMID:1702709 PMID:22461452 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:68734, RGD:8549758 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit enables IDA
IC
IMP
IGI
ISO
IBA		 PMID:21540349
(PMID:18387948), (PMID:8906617)
GO_REF:0000033
MGI:1926253|MGI:87888 (PMID:11222635), (PMID:15569257), (PMID:15741168), (PMID:17470777), (PMID:9614223)		 RGD
GO_Central		 PMID:8906617 PMID:9614223 PMID:11222635 PMID:15569257 PMID:15741168 More... GO_REF:0000033, RGD:727635, RGD:2303190, RGD:8549520, RGD:12790638 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit enables IC
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9030613 GO_REF:0000033, RGD:2303190 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit enables IC
ISO
IEA
IBA		 (PMID:18387948)
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:18387948 PMID:9030613 GO_REF:0000002 GO_REF:0000033, RGD:2303190 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit enables
contributes_to		 IDA
IBA
ISO		 GO_REF:0000033
MGI:87890|MGI:87895 (PMID:8798466)
MGI:87885|MGI:87890|MGI:87894|MGI:87895 (PMID:2383398)		 GO_Central
RGD		 PMID:2383398 PMID:8798466 PMID:1702709 PMID:22461452 GO_REF:0000033, RGD:68734, RGD:8549758 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit enables
contributes_to		 IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
MGI:87885|MGI:87890|MGI:87893 (PMID:2383398)		 InterPro
GO_Central
RGD		 PMID:2383398 PMID:22461452 GO_REF:0000002 GO_REF:0000033, RGD:8549758 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit enables IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
MGI:87885|MGI:87890|MGI:87893 (PMID:2383398), (PMID:8798466)		 InterPro
GO_Central
RGD		 PMID:2383398 PMID:8798466 PMID:1702709 PMID:22461452 GO_REF:0000002 GO_REF:0000033, RGD:68734, RGD:8549758 NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 762
          monoatomic ion channel activity 451
            ligand-gated monoatomic ion channel activity 185
              ligand-gated monoatomic cation channel activity 130
                acetylcholine-gated monoatomic cation-selective channel activity 16
Path 2
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        passive transmembrane transporter activity 511
          channel activity 511
            gated channel activity 334
              ligand-gated channel activity 190
                ligand-gated monoatomic ion channel activity 185
                  extracellular ligand-gated monoatomic ion channel activity 70
                    transmitter-gated monoatomic ion channel activity 60
                      transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 53
                        acetylcholine-gated monoatomic cation-selective channel activity 16
paths to the root