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ONTOLOGY REPORT - ANNOTATIONS

Term:response to cold
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Accession:GO:0009409 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
Synonyms:related_synonym: freezing tolerance


show annotations for term's descendants           Sort by:
response to cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADL acyl-CoA dehydrogenase long chain acts_upstream_of_or_within ISO (PMID:21151927) MGI PMID:21151927 NCBI chr2B:97,445,421...97,483,514
Ensembl chr2B:215,847,775...215,885,524 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16121256) Ensembl
MGI		 PMID:16121256 GO_REF:0000107 NCBI chr 1:74,939,477...74,978,815
Ensembl chr 1:76,911,763...76,950,840 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21151927) Ensembl
MGI		 PMID:21151927 GO_REF:0000107 NCBI chr17:7,249,717...7,255,165
Ensembl chr17:7,234,283...7,242,417 		JBrowse link
G ACOT11 acyl-CoA thioesterase 11 involved_in ISO (PMID:11696000) BHF-UCL PMID:11696000 NCBI chr 1:53,823,059...53,884,249
Ensembl chr 1:55,411,806...55,496,661 		JBrowse link
G ADRB1 adrenoceptor beta 1 acts_upstream_of_or_within ISO (PMID:12161655), (PMID:12387862) MGI PMID:12161655 PMID:12387862 NCBI chr10:110,642,491...110,646,595 JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12161655), (PMID:12387862) Ensembl
MGI		 PMID:12161655 PMID:12387862 GO_REF:0000107 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892 		JBrowse link
G ADRB3 adrenoceptor beta 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12161655), (PMID:12387862) Ensembl
MGI		 PMID:12161655 PMID:12387862 GO_REF:0000107 NCBI chr 8:37,263,730...37,267,475
Ensembl chr 8:34,441,311...34,443,949 		JBrowse link
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:12574102) MGI PMID:12574102 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G BLTP1 bridge-like lipid transfer protein family member 1 acts_upstream_of_or_within ISO (PMID:36357390) MGI PMID:36357390 NCBI chr 4:114,346,807...114,558,993
Ensembl chr 4:125,482,532...125,694,099 		JBrowse link
G CDH8 cadherin 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17392463) Ensembl
MGI		 PMID:17392463 GO_REF:0000107 NCBI chr16:41,935,706...42,326,055
Ensembl chr16:61,054,214...61,437,569 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33357458)
(PMID:29374543)		 Ensembl
MGI		 PMID:29374543 PMID:33357458 GO_REF:0000107 NCBI chr10:85,938,240...85,976,610
Ensembl chr10:89,477,082...89,516,874 		JBrowse link
G LOC100977072 neuronal acetylcholine receptor subunit alpha-7 involved_in ISO (PMID:19230830) ARUK-UCL PMID:19230830 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194 		JBrowse link
G LRP11 LDL receptor related protein 11 involved_in ISO (PMID:25262641) AgBase PMID:25262641 NCBI chr 6:147,630,742...147,676,322
Ensembl chr 6:152,336,565...152,381,664 		JBrowse link
G METRNL meteorin like, glial cell differentiation regulator involved_in ISO (PMID:24906147) UniProt PMID:24906147 NCBI chr17:77,511,681...77,527,677
Ensembl chr17:83,287,606...83,301,637 		JBrowse link
G P2RX3 purinergic receptor P2X 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15927378) Ensembl
MGI		 PMID:15927378 GO_REF:0000107 NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120 		JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16631141) Ensembl
MGI		 PMID:16631141 GO_REF:0000107 NCBI chr  X:41,128,785...41,133,284
Ensembl chr  X:48,988,948...48,990,028 		JBrowse link
G PLAC8 placenta associated 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21982742) Ensembl
MGI		 PMID:21982742 GO_REF:0000107 NCBI chr 4:41,089,847...41,115,061
Ensembl chr 4:46,943,940...46,964,131 		JBrowse link
G RBM3 RNA binding motif protein 3 acts_upstream_of_or_within ISO (PMID:15684048) MGI PMID:15684048 NCBI chr  X:40,872,745...40,876,611
Ensembl chr  X:48,734,777...48,738,077 		JBrowse link
G SCN11A sodium voltage-gated channel alpha subunit 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,741,485...38,948,400
Ensembl chr 3:39,024,921...39,128,015 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17130465) Ensembl
MGI		 PMID:17130465 GO_REF:0000107 NCBI chr19:16,956,000...16,993,429
Ensembl chr19:17,929,785...17,966,171 		JBrowse link
G THRA thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12869545) Ensembl
MGI		 PMID:12869545 GO_REF:0000107 NCBI chr17:17,196,459...17,226,263 JBrowse link
G TMEM135 transmembrane protein 135 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21151927) Ensembl
MGI		 PMID:21151927 GO_REF:0000107 NCBI chr11:82,089,010...82,360,744
Ensembl chr11:85,696,632...85,966,778 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16630838)
(PMID:12654248)		 MGI
Ensembl		 PMID:12654248 PMID:16630838 GO_REF:0000107 NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627 		JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17481392)
(PMID:17481391)
(PMID:12654248), (PMID:17015441)
(PMID:17538622)		 Ensembl
MGI		 PMID:12654248 PMID:17015441 PMID:17481391 PMID:17481392 PMID:17538622 GO_REF:0000107 NCBI chr2B:121,160,045...121,261,645
Ensembl chr2B:240,039,104...240,130,524 		JBrowse link
G VGF VGF nerve growth factor inducible involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16631141) Ensembl
MGI		 PMID:16631141 GO_REF:0000107 NCBI chr 7:93,302,956...93,307,892 JBrowse link
G ZNF516 zinc finger protein 516 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:69,748,472...69,891,026
Ensembl chr18:73,026,076...73,103,609 		JBrowse link
cellular response to cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CIDEA cell death inducing DFFA like effector a involved_in ISO (PMID:28763438) MGI PMID:28763438 NCBI chr18:2,051,880...2,075,909 JBrowse link
G CIRBP cold inducible RNA binding protein acts_upstream_of_or_within ISO (PMID:9151692) MGI PMID:9151692
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:76,853,053...76,963,530
Ensembl chr13:96,033,605...96,114,165 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,871,867...18,973,380
Ensembl chr15:37,120,044...37,229,211 		JBrowse link
G LIPE lipase E, hormone sensitive type acts_upstream_of_or_within ISO (PMID:30862682) MGI PMID:30862682 NCBI chr19:39,289,162...39,315,067
Ensembl chr19:47,881,292...47,907,066 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO (PMID:29400713) MGI PMID:29400713 NCBI chr17:9,476,482...9,489,661
Ensembl chr17:9,657,847...9,671,040 		JBrowse link
G PLIN1 perilipin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30862682) Ensembl
MGI		 PMID:30862682 GO_REF:0000107 NCBI chr15:68,357,815...68,375,062
Ensembl chr15:87,565,468...87,577,301 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30862682) Ensembl
MGI		 PMID:30862682 GO_REF:0000107 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205 		JBrowse link
G RNF34 ring finger protein 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:118,998,436...119,022,823
Ensembl chr12:122,373,172...122,402,693 		JBrowse link
G SAXO1 stabilizer of axonemal microtubules 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:18,741,406...18,868,726
Ensembl chr 9:19,234,977...19,346,886 		JBrowse link
G SCN11A sodium voltage-gated channel alpha subunit 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,741,485...38,948,400
Ensembl chr 3:39,024,921...39,128,015 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO RGD PMID:15452191 RGD:1625557 NCBI chr 1:26,359,818...26,418,910
Ensembl chr 1:27,414,937...27,475,089 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:21068322 RGD:10043615 NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627 		JBrowse link
G UCP1 uncoupling protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:132,921,033...132,930,714
Ensembl chr 4:144,230,858...144,240,178 		JBrowse link
G VWF von Willebrand factor ISO RGD PMID:12084999 RGD:11079231 NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153 		JBrowse link
cellular response to freezing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRAXAS2 abraxas 2, BRISC complex subunit acts_upstream_of_or_within ISO (PMID:22974638) MGI PMID:22974638 NCBI chr10:121,360,324...121,397,994
Ensembl chr10:125,628,423...125,664,833 		JBrowse link
cold acclimation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:102,755,388...102,818,686
Ensembl chr12:106,151,969...106,206,879 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta ISO RGD PMID:9163327 RGD:13799276 NCBI chr12:32,264,570...32,272,419
Ensembl chr12:32,519,749...32,527,753 		JBrowse link
G ATP5MC1 ATP synthase membrane subunit c locus 1 ISO RGD PMID:9163327 RGD:13799276 NCBI chr17:8,641,273...8,644,395
Ensembl chr17:8,828,117...8,831,190 		JBrowse link
G MB myoglobin ISO RGD PMID:3784148 RGD:490007147 NCBI chr22:16,612,519...16,645,333
Ensembl chr22:34,452,451...34,463,224 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:21945600 RGD:6484546 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505 		JBrowse link
G SAXO1 stabilizer of axonemal microtubules 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:18,741,406...18,868,726
Ensembl chr 9:19,234,977...19,346,886 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16641
    response to stimulus 8561
      response to stress 3954
        response to cold 46
          cellular response to cold + 17
          cold acclimation 6
          response to freezing + 1
          vernalization response + 0
Path 2
Term Annotations click to browse term
  biological_process 16641
    response to stimulus 8561
      response to abiotic stimulus 1482
        response to temperature stimulus 180
          response to cold 46
            cellular response to cold + 17
            cold acclimation 6
            response to freezing + 1
            vernalization response + 0
paths to the root