LIPE (lipase E, hormone sensitive type) - Rat Genome Database

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Gene: LIPE (lipase E, hormone sensitive type) Pan paniscus
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Symbol: LIPE
Name: lipase E, hormone sensitive type
RGD ID: 11938379
Description: ENCODES a protein that exhibits hydrolase activity, acting on ester bonds (ortholog); monoacylglycerol lipase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to cold (ortholog); diacylglycerol catabolic process (ortholog); ether lipid metabolic process (ortholog); ASSOCIATED WITH arteriosclerosis (ortholog); Carpenter Syndrome 2 (ortholog); congenital hypoplastic anemia (ortholog); FOUND IN extracellular space (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hormone-sensitive lipase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,506,457 - 48,534,733 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,375,028 - 50,400,941 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,289,162 - 39,315,067 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,881,292 - 47,907,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,881,292 - 47,907,066 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LIPE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,506,457 - 48,534,733 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,375,028 - 50,400,941 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,289,162 - 39,315,067 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,881,292 - 47,907,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,881,292 - 47,907,066 (-)Ensemblpanpan1.1panPan2
LIPE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,401,514 - 42,427,388 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1942,401,497 - 42,427,388 (-)EnsemblGRCh38hg38GRCh38
GRCh371942,905,666 - 42,931,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,597,506 - 47,623,418 (-)NCBINCBI36Build 36hg18NCBI36
Build 341947,597,505 - 47,623,418NCBI
Celera1939,706,455 - 39,732,367 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1939,335,797 - 39,361,703 (-)NCBIHuRef
CHM1_11942,907,316 - 42,933,231 (-)NCBICHM1_1
T2T-CHM13v2.01945,220,900 - 45,246,776 (-)NCBIT2T-CHM13v2.0
Lipe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,078,952 - 25,097,911 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,078,952 - 25,098,135 (-)EnsemblGRCm39 Ensembl
GRCm38725,379,527 - 25,398,486 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,379,527 - 25,398,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,164,546 - 26,181,006 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,088,287 - 25,104,747 (-)NCBIMGSCv36mm8
Celera719,994,853 - 20,011,313 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.78NCBI
Lipe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8190,093,433 - 90,112,117 (-)NCBIGRCr8
mRatBN7.2180,965,612 - 80,984,313 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,965,627 - 80,984,310 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx186,357,834 - 86,376,510 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,909,045 - 94,927,749 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,113,613 - 88,132,294 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,248,031 - 82,266,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,248,046 - 82,266,727 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,511,504 - 83,530,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,663,791 - 80,682,480 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1180,741,901 - 80,760,591 (-)NCBI
Celera175,407,246 - 75,425,931 (-)NCBICelera
Cytogenetic Map1q21NCBI
Lipe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555514,410 - 530,759 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955555511,085 - 531,165 (+)NCBIChiLan1.0ChiLan1.0
LIPE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,987,862 - 112,006,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,988,029 - 112,006,461 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,412,499 - 111,431,532 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,598,798 - 112,617,839 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,607,340 - 112,617,499 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,153,322 - 112,171,913 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,788,548 - 111,807,575 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,715,381 - 112,734,429 (+)NCBIUU_Cfam_GSD_1.0
Lipe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,772,658 - 15,792,162 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706128,133 - 141,276 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706122,939 - 139,506 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIPE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,540,708 - 49,560,125 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,543,671 - 49,560,126 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,443,742 - 45,454,621 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q12NCBI
LIPE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,604,822 - 36,630,648 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,605,126 - 36,630,376 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,849,833 - 14,875,994 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lipe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907363,572 - 379,194 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907360,462 - 379,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000061981   ⟹   ENSPPAP00000039072
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1947,881,292 - 47,907,066 (-)Ensembl
RefSeq Acc Id: XM_003811755   ⟹   XP_003811803
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,534,733 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,400,941 (-)NCBI
Mhudiblu_PPA_v01939,289,162 - 39,315,067 (-)NCBI
PanPan1.11947,881,292 - 47,907,066 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055103685   ⟹   XP_054959660
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,529,219 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,397,810 (-)NCBI
RefSeq Acc Id: XM_055103686   ⟹   XP_054959661
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,517,425 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,386,107 (-)NCBI
RefSeq Acc Id: XM_055103687   ⟹   XP_054959662
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,516,377 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,384,967 (-)NCBI
RefSeq Acc Id: XM_055103688   ⟹   XP_054959663
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,528,531 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,397,112 (-)NCBI
RefSeq Acc Id: XM_055103689   ⟹   XP_054959664
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,517,293 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,385,907 (-)NCBI
RefSeq Acc Id: XM_057300624   ⟹   XP_057156607
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,528,910 (-)NCBI
NHGRI_mPanPan11950,375,028 - 50,397,501 (-)NCBI
RefSeq Acc Id: XM_063600324   ⟹   XP_063456394
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22048,506,457 - 48,528,502 (-)NCBI
RefSeq Acc Id: XP_003811803   ⟸   XM_003811755
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CLN7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000039072   ⟸   ENSPPAT00000061981
RefSeq Acc Id: XP_054959660   ⟸   XM_055103685
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054959663   ⟸   XM_055103688
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054959661   ⟸   XM_055103686
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054959664   ⟸   XM_055103689
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054959662   ⟸   XM_055103687
- Peptide Label: isoform X4
RefSeq Acc Id: XP_057156607   ⟸   XM_057300624
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063456394   ⟸   XM_063600324
- Peptide Label: isoform X4

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042254 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061981.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_3 UniProtKB/TrEMBL
  HSL_N UniProtKB/TrEMBL
  Lipase_GDXG_HIS_AS UniProtKB/TrEMBL
  Lipase_GDXG_put_SER_AS UniProtKB/TrEMBL
NCBI Gene LIPE ENTREZGENE
PANTHER HORMONE-SENSITIVE LIPASE UniProtKB/TrEMBL
  TRIACYLGLYCEROL LIPASE UniProtKB/TrEMBL
Pfam Abhydrolase_3 UniProtKB/TrEMBL
  HSL_N UniProtKB/TrEMBL
PROSITE LIPASE_GDXG_HIS UniProtKB/TrEMBL
  LIPASE_GDXG_SER UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9CLN7 ENTREZGENE, UniProtKB/TrEMBL