NFE2L1 (NFE2 like bZIP transcription factor 1) - Rat Genome Database

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Gene: NFE2L1 (NFE2 like bZIP transcription factor 1) Pan paniscus
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Symbol: NFE2L1
Name: NFE2 like bZIP transcription factor 1
RGD ID: 11687397
Description: ENCODES a protein that exhibits cholesterol binding (ortholog); chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell redox homeostasis (ortholog); cellular homeostasis (ortholog); cellular response to cholesterol (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); hepatocellular carcinoma (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: endoplasmic reticulum membrane sensor NFE2L1; nuclear factor (erythroid-derived 2)-like 1; nuclear factor erythroid 2-related factor 1; nuclear factor, erythroid 2 like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,042,363 - 17,055,684 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,007,939 - 19,021,206 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,476,482 - 9,489,661 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,657,847 - 9,671,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,657,847 - 9,671,040 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NFE2L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,042,363 - 17,055,684 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,007,939 - 19,021,206 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,476,482 - 9,489,661 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,657,847 - 9,671,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,657,847 - 9,671,040 (-)Ensemblpanpan1.1panPan2
NFE2L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381748,048,359 - 48,061,545 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1748,048,329 - 48,061,545 (+)EnsemblGRCh38hg38GRCh38
GRCh371746,125,721 - 46,138,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,480,745 - 43,493,841 (+)NCBINCBI36Build 36hg18NCBI36
Build 341743,480,744 - 43,493,840NCBI
Celera1742,578,502 - 42,591,724 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,494,079 - 41,507,301 (+)NCBIHuRef
CHM1_11746,190,680 - 46,203,900 (+)NCBICHM1_1
T2T-CHM13v2.01748,910,172 - 48,923,361 (+)NCBIT2T-CHM13v2.0
Nfe2l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,708,239 - 96,720,810 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,708,240 - 96,720,794 (-)EnsemblGRCm39 Ensembl
GRCm381196,817,414 - 96,829,968 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,817,414 - 96,829,968 (-)EnsemblGRCm38mm10GRCm38
MGSCv371196,678,728 - 96,691,282 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,633,521 - 96,644,045 (-)NCBIMGSCv36mm8
Celera11106,466,769 - 106,479,303 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1160.12NCBI
Nfe2l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81082,296,824 - 82,309,472 (-)NCBIGRCr8
mRatBN7.21081,796,055 - 81,812,926 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,800,366 - 81,832,318 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1086,748,076 - 86,760,626 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01086,246,127 - 86,258,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,638,722 - 81,651,272 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01084,686,762 - 84,699,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,682,460 - 84,698,886 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,479,677 - 84,492,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41085,570,238 - 85,577,636 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11085,588,909 - 85,601,415 (-)NCBI
Celera1080,562,053 - 80,574,604 (-)NCBICelera
Cytogenetic Map10q31NCBI
Nfe2l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,088,906 - 13,099,839 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,088,680 - 13,099,839 (-)NCBIChiLan1.0ChiLan1.0
NFE2L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,344,697 - 24,356,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,346,585 - 24,362,646 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,810,726 - 23,822,715 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,138,680 - 25,150,670 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,138,689 - 25,156,398 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,908,140 - 23,920,129 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,168,769 - 24,180,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,296,588 - 24,308,159 (+)NCBIUU_Cfam_GSD_1.0
Nfe2l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,795,986 - 23,810,579 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,266,347 - 13,279,206 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,265,269 - 13,279,164 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFE2L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,303,399 - 24,316,763 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,303,381 - 24,316,765 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,300,897 - 24,308,045 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NFE2L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,449,601 - 68,463,030 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,449,898 - 68,461,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,501,780 - 39,515,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfe2l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247954,652,637 - 4,662,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247954,652,221 - 4,663,341 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003827492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003827493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008952844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055101280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055101281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055101282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063598953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063598954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063598955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063598956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000040027   ⟹   ENSPPAP00000017325
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl179,657,847 - 9,670,659 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000040032   ⟹   ENSPPAP00000017330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl179,658,378 - 9,671,040 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000040039   ⟹   ENSPPAP00000017337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl179,659,690 - 9,664,628 (-)Ensembl
RefSeq Acc Id: XM_003827492   ⟹   XP_003827540
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,684 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,021,206 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,489,660 (-)NCBI
PanPan1.1179,657,847 - 9,671,040 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003827493   ⟹   XP_003827541
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,209 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,014,779 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,483,255 (-)NCBI
PanPan1.1179,659,690 - 9,664,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952833   ⟹   XP_008951081
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,135 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,020,693 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,489,242 (-)NCBI
PanPan1.1179,659,702 - 9,670,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952834   ⟹   XP_008951082
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,551 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,021,119 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,489,661 (-)NCBI
PanPan1.1179,657,847 - 9,671,040 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952836   ⟹   XP_008951084
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,550 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,021,119 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,489,660 (-)NCBI
PanPan1.1179,657,847 - 9,671,040 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952839   ⟹   XP_008951087
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,233 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,014,803 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,483,128 (-)NCBI
PanPan1.1179,657,847 - 9,664,690 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952840   ⟹   XP_008951088
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,017 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,014,591 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,483,128 (-)NCBI
PanPan1.1179,657,847 - 9,664,506 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952844   ⟹   XP_008951092
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,209 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,014,779 (-)NCBI
Mhudiblu_PPA_v0179,476,482 - 9,483,285 (-)NCBI
PanPan1.1179,659,497 - 9,664,663 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055101280   ⟹   XP_054957255
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,135 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,020,692 (-)NCBI
RefSeq Acc Id: XM_055101281   ⟹   XP_054957256
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,550 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,021,118 (-)NCBI
RefSeq Acc Id: XM_055101282   ⟹   XP_054957257
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,125 (-)NCBI
NHGRI_mPanPan11719,007,939 - 19,020,693 (-)NCBI
RefSeq Acc Id: XM_063598953   ⟹   XP_063455023
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,055,126 (-)NCBI
RefSeq Acc Id: XM_063598954   ⟹   XP_063455024
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,203 (-)NCBI
RefSeq Acc Id: XM_063598955   ⟹   XP_063455025
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,181 (-)NCBI
RefSeq Acc Id: XM_063598956   ⟹   XP_063455026
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21917,042,363 - 17,049,209 (-)NCBI
RefSeq Acc Id: XP_003827540   ⟸   XM_003827492
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ANQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951087   ⟸   XM_008952839
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008951088   ⟸   XM_008952840
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008951084   ⟸   XM_008952836
- Peptide Label: isoform X3
- UniProtKB: A0A2R9ANQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951092   ⟸   XM_008952844
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_003827541   ⟸   XM_003827493
- Peptide Label: isoform X7
- UniProtKB: A0A2R9AIZ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951082   ⟸   XM_008952834
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008951081   ⟸   XM_008952833
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ANQ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000017325   ⟸   ENSPPAT00000040027
Ensembl Acc Id: ENSPPAP00000017337   ⟸   ENSPPAT00000040039
Ensembl Acc Id: ENSPPAP00000017330   ⟸   ENSPPAT00000040032
RefSeq Acc Id: XP_054957256   ⟸   XM_055101281
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054957257   ⟸   XM_055101282
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054957255   ⟸   XM_055101280
- Peptide Label: isoform X3
- UniProtKB: A0A2R9ANQ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063455023   ⟸   XM_063598953
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063455026   ⟸   XM_063598956
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063455024   ⟸   XM_063598954
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063455025   ⟸   XM_063598955
- Peptide Label: isoform X9
Protein Domains
bZIP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031737 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040027.1 UniProtKB/TrEMBL
  ENSPPAT00000040032.1 UniProtKB/TrEMBL
  ENSPPAT00000040039.1 UniProtKB/TrEMBL
Gene3D-CATH Transcription factor, Skn-1-like, DNA-binding domain UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
  NFE2-like UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report pps:100988657 UniProtKB/TrEMBL
NCBI Gene NFE2L1 ENTREZGENE
PANTHER NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR UniProtKB/TrEMBL
  PTHR24411:SF31 UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP SSF47454 UniProtKB/TrEMBL
UniProt A0A2R9AIZ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ANQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ANQ6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-10-05 NFE2L1  NFE2 like bZIP transcription factor 1  NFE2L1  nuclear factor, erythroid 2 like 1  Symbol and/or name change 5135510 APPROVED