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ONTOLOGY REPORT - ANNOTATIONS

Term:malate metabolic process
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Accession:GO:0006108 term browser browse the term
Definition:The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
Synonyms:exact_synonym: malate metabolism


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malate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G D2hgdh D-2-hydroxyglutarate dehydrogenase involved_in ISO
ISS
IEA		 (PMID:33431826)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:33431826 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:94,350,555...94,368,384
Ensembl chr 9:94,350,576...94,368,382 		JBrowse link
G Fh fumarate hydratase involved_in ISO
IBA		 (PMID:30761759)
(PMID:21498518)
GO_REF:0000033		 RGD
GO_Central		 PMID:21498518 PMID:30761759 GO_REF:0000033 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Lipf lipase F, gastric type acts_upstream_of_or_within IDA PMID:15809022 MGI PMID:15809022 RGD:1582471 NCBI chr 1:231,493,498...231,511,845
Ensembl chr 1:231,493,498...231,511,845 		JBrowse link
G Mdh1 malate dehydrogenase 1 involved_in IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:17447164 PMID:12351438 GO_REF:0000002 GO_REF:0000033, RGD:1624966, RGD:2303499 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mdh1b malate dehydrogenase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933 		JBrowse link
G Mdh2 malate dehydrogenase 2 involved_in IDA
ISO
IEA		 (PMID:16740313), (PMID:6576816)
GO_REF:0000002		 RGD
InterPro		 PMID:6576816 PMID:16740313 PMID:1898089 PMID:12351438 GO_REF:0000002, RGD:1582472, RGD:2303499 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Me1 malic enzyme 1 involved_in ISS
ISO
IEA
IBA		 PMID:7622060
(PMID:7622060), (PMID:8187880)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:7622060 PMID:8187880 PMID:7622060 PMID:8187880 GO_REF:0000033 GO_REF:0000107, RGD:8553596, RGD:8554832 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Me2 malic enzyme 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987 		JBrowse link
G Me3 malic enzyme 3 involved_in ISO
IBA		 (PMID:7818469)
GO_REF:0000033		 RGD
GO_Central		 PMID:7818469 GO_REF:0000033 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        small molecule metabolic process 1916
          organic acid metabolic process 1046
            oxoacid metabolic process 1033
              carboxylic acid metabolic process 1018
                dicarboxylic acid metabolic process 103
                  malate metabolic process 9
paths to the root