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ONTOLOGY REPORT - ANNOTATIONS

Term:dicarboxylic acid metabolic process
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Accession:GO:0043648 term browser browse the term
Definition:The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
Synonyms:exact_synonym: dicarboxylate metabolic process;   dicarboxylate metabolism;   dicarboxylic acid metabolism


show annotations for term's descendants           Sort by:
 
dicarboxylic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 involved_in ISO (PMID:16940157)
(MGI:3663233|PMID:16940157)		 RGD PMID:16940157 MGI:3663233 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP
IDA		 RGD PMID:7562489 PMID:2837211 RGD:1627658, RGD:2289377 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IDA RGD PMID:14522984 RGD:1582383 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase IDA RGD PMID:2689175 RGD:1599320 NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603 		JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)		 RGD PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO (PMID:12937168) RGD PMID:12937168 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
10-formyltetrahydrofolate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IEA GO_REF:0000002
GO_REF:0000104		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
10-formyltetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IDA RGD PMID:21163947 RGD:7244288 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
2-oxoglutarate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
ISS		 (PMID:18620547)
GO_REF:0000024		 RGD
UniProt		 PMID:18620547 GO_REF:0000024 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Dld dihydrolipoamide dehydrogenase IDA RGD PMID:3571202 RGD:2306876 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase involved_in IDA
ISO		 (PMID:10806400) RGD PMID:10806400 PMID:3571202 RGD:2306876 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 involved_in ISO (PMID:11863375) RGD PMID:11863375 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 involved_in ISO
ISS		 (PMID:19935646)
GO_REF:0000024		 RGD
UniProt		 PMID:19935646 GO_REF:0000024 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha IDA RGD PMID:938457 RGD:2306828 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084 		JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta IDA RGD PMID:938457 RGD:2306828 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982 		JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma IDA RGD PMID:938457 RGD:2306828 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in ISO (MGI:3835225|PMID:19029248) RGD PMID:19029248 MGI:3835225 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
G Mrps36 mitochondrial ribosomal protein S36 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:31,870,549...31,878,335
Ensembl chr 2:31,870,551...31,880,730 		JBrowse link
G Ogdh oxoglutarate dehydrogenase involved_in IDA
ISO		 (PMID:24495017), (PMID:29211711) RGD PMID:24495017 PMID:29211711 PMID:3571202 PMID:9712727 RGD:2306876, RGD:2306877 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Ogdhl oxoglutarate dehydrogenase L involved_in IDA PMID:18783430 UniProt PMID:18783430 RGD:42721998 NCBI chr16:7,578,305...7,604,385
Ensembl chr16:7,578,367...7,604,386 		JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase involved_in ISO (PMID:16186124) RGD PMID:16186124 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409 		JBrowse link
G Tat tyrosine aminotransferase involved_in ISO (PMID:7999802)
(MGI:5430853|PMID:21153519)		 RGD PMID:7999802 PMID:21153519 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3604881 (MGI:3604426|PMID:12559843)		 Ensembl
RGD		 PMID:12559843 GO_REF:0000107 MGI:3604426 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Glul glutamate-ammonia ligase TAS
IDA		 RGD PMID:1674354 PMID:28323 RGD:632694, RGD:2301547 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
arginine catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oat ornithine aminotransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:53641|PMID:4193185)		 RGD PMID:4193185 PMID:21873635 MGI:53641, RGD:13792537 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddo D-aspartate oxidase involved_in IBA
ISO		 PMID:21873635
(PMID:9163533)		 RGD PMID:9163533 PMID:21873635 RGD:13792537 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISO (PMID:2241899) RGD PMID:2241899 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in IBA
ISO		 PMID:21873635
(PMID:2567216)		 RGD PMID:2567216 PMID:21873635 RGD:13792537 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adss adenylosuccinate synthase IDA RGD PMID:71897 RGD:5135533 NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604 		JBrowse link
G Adss1 adenylosuccinate synthase 1 IDA RGD PMID:3759987 RGD:5135303 NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998 		JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in ISO (PMID:7977368) RGD PMID:7977368 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in ISO MGI:1856982 (MGI:5926996|PMID:28701731) RGD PMID:28701731 MGI:5926996 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Ddo D-aspartate oxidase acts_upstream_of_or_within ISO MGI:3625623 (MGI:3617951|PMID:16525061) RGD PMID:16525061 MGI:3617951 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in IDA
ISS		 GO_REF:0000024 UniProt
RGD		 PMID:2837211 GO_REF:0000024, RGD:2289377 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in IMP
ISS		 GO_REF:0000024 UniProt
RGD		 PMID:12686151 GO_REF:0000024, RGD:2289396 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
dicarboxylic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 involved_in ISO (PMID:16141203) RGD PMID:16141203 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acot8 acyl-CoA thioesterase 8 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16141203)		 Ensembl
RGD		 PMID:16141203 GO_REF:0000107 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
dihydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:8948466 RGD:5144056 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889 		JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IBA
ISO		 PMID:21873635
(PMID:2303423), (PMID:23707606)		 RGD PMID:2303423 PMID:23707606 PMID:11502523 PMID:21873635 PMID:3970530 RGD:1298877, RGD:13792537, RGD:2300196 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212 		JBrowse link
folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in IBA
IDA		 PMID:21873635
PMID:20424322		 GO_Central
BHF-UCL		 PMID:21873635 PMID:20424322 RGD:13792537, RGD:10054082 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Folr1 folate receptor alpha acts_upstream_of_or_within ISO MGI:2383986 (MGI:2669340|PMID:12854656) RGD PMID:12854656 MGI:2669340 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Gnmt glycine N-methyltransferase TAS RGD PMID:12054489 RGD:728472 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5512657|PMID:24074862)
(PMID:11466310)		 UniProt
RGD		 PMID:11466310 PMID:24074862 GO_REF:0000024 MGI:5512657 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA
ISO		 PMID:21873635
(PMID:11278996)		 RGD PMID:11278996 PMID:21873635 RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
fumarate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fh fumarate hydratase involved_in TAS
ISO
ISS
IBA
IDA		 (MGI:5496931|PMID:23643539)
GO_REF:0000024
(PMID:21498518)
(PMID:26237645), (PMID:30718813)
(PMID:30761759)
PMID:21873635		 RGD
UniProt		 PMID:21498518 PMID:23643539 PMID:26237645 PMID:30718813 PMID:30761759 More... GO_REF:0000024 MGI:5496931, RGD:632664, RGD:13792537, RGD:2306828 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IEA
ISO
IBA
ISS		 GO_REF:0000107
(MGI:5320252|PMID:22228304)
PMID:21873635
GO_REF:0000024
(PMID:16899818), (PMID:22049910)		 Ensembl
RGD
UniProt		 PMID:16899818 PMID:22049910 PMID:22228304 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5320252, RGD:13792537 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gls2 glutaminase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
glutamate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glud1 glutamate dehydrogenase 1 involved_in TAS
IBA
ISO		 PMID:21873635
(PMID:11032875), (PMID:6121377)		 RGD PMID:6121377 PMID:11032875 PMID:12684230 PMID:21873635 RGD:1601355, RGD:13792537 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within IDA
ISO		 (MGI:53641|PMID:4193185) RGD PMID:4193185 PMID:16489927 MGI:53641, RGD:13504861 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within IDA
ISO		 (MGI:53641|PMID:4193185) RGD PMID:4193185 PMID:16489927 MGI:53641, RGD:13504861 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adhfe1 alcohol dehydrogenase, iron containing, 1 involved_in ISO
ISS		 (PMID:16435184)
GO_REF:0000024		 RGD
UniProt		 PMID:16435184 GO_REF:0000024 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517 		JBrowse link
glutamate decarboxylation to succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad2 glutamate decarboxylase 2 IDA RGD PMID:8999827 RGD:1625237 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
ISS		 (PMID:18620547)
GO_REF:0000024		 RGD
UniProt		 PMID:18620547 GO_REF:0000024 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761) RGD PMID:11092761 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180159 (MGI:3767902|PMID:17854388)		 Ensembl
RGD		 PMID:17854388 GO_REF:0000107 MGI:3767902 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in ISO MGI:1856982 (MGI:5926996|PMID:28701731) RGD PMID:28701731 MGI:5926996 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Dglucy D-glutamate cyclase involved_in IBA
ISO		 PMID:21873635
(MGI:5901965|PMID:28266638)		 RGD PMID:28266638 PMID:21873635 MGI:5901965, RGD:13792537 NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910 		JBrowse link
G Fpgs folylpolyglutamate synthase involved_in ISO (PMID:3619447) RGD PMID:3619447 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit involved_in ISO
ISS		 (PMID:12663448), (PMID:2294991), (PMID:9841880)
GO_REF:0000024		 RGD
UniProt		 PMID:2294991 PMID:9841880 PMID:12663448 GO_REF:0000024 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit involved_in ISO
ISS		 (PMID:9841880), (PMID:9895302)
GO_REF:0000024		 RGD
UniProt		 PMID:9841880 PMID:9895302 GO_REF:0000024 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
ISS		 (PMID:21447318), (PMID:24047895)
GO_REF:0000024		 RGD
UniProt		 PMID:21447318 PMID:24047895 GO_REF:0000024 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Glul glutamate-ammonia ligase IDA RGD PMID:4403443 RGD:2301548 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Nags N-acetylglutamate synthase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2388220|PMID:12049647)		 RGD PMID:12049647 PMID:21873635 MGI:2388220, RGD:13792537 NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465 		JBrowse link
G Tat tyrosine aminotransferase involved_in ISO
ISS		 (PMID:7999802)
(MGI:5430853|PMID:21153519)
GO_REF:0000024		 RGD
UniProt		 PMID:7999802 PMID:21153519 GO_REF:0000024 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
histidine catabolic process to glutamate and formamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Hal histidine ammonia lyase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Uroc1 urocanate hydratase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591 		JBrowse link
histidine catabolic process to glutamate and formate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Hal histidine ammonia lyase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Uroc1 urocanate hydratase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591 		JBrowse link
malate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G D2hgdh D-2-hydroxyglutarate dehydrogenase involved_in ISO
ISS		 (PMID:33431826)
GO_REF:0000024		 RGD
UniProt		 PMID:33431826 GO_REF:0000024 NCBI chr 9:94,350,555...94,368,384
Ensembl chr 9:94,350,576...94,368,382 		JBrowse link
G Fh fumarate hydratase involved_in IDA
IBA
ISO		 PMID:21873635
(PMID:21498518)
(PMID:30761759)		 RGD PMID:21498518 PMID:30761759 PMID:938457 PMID:21873635 RGD:2306828, RGD:13792537 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Lipf lipase F, gastric type acts_upstream_of_or_within IDA PMID:15809022 MGI PMID:15809022 RGD:1582471 NCBI chr 1:231,493,498...231,511,845
Ensembl chr 1:231,493,498...231,511,845 		JBrowse link
G Mdh1 malate dehydrogenase 1 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:17447164 PMID:21873635 PMID:12351438 RGD:1624966, RGD:13792537, RGD:2303499 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mdh1b malate dehydrogenase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933 		JBrowse link
G Mdh2 malate dehydrogenase 2 involved_in IDA
ISO		 (PMID:16740313), (PMID:6576816) RGD PMID:6576816 PMID:16740313 PMID:1898089 PMID:938457 PMID:12351438 RGD:1582472, RGD:2306828, RGD:2303499 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Me1 malic enzyme 1 involved_in ISS
IEA
IBA
ISO		 PMID:7622060
GO_REF:0000107
PMID:21873635
PMID:8187880
(PMID:7622060), (PMID:8187880)		 Ensembl
RGD		 PMID:7622060 PMID:8187880 PMID:7622060 PMID:21873635 PMID:8187880 GO_REF:0000107, RGD:8553596, RGD:13792537, RGD:8554832 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Me2 malic enzyme 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987 		JBrowse link
G Me3 malic enzyme 3 involved_in IBA
ISO		 PMID:21873635
(PMID:7818469)		 RGD PMID:7818469 PMID:21873635 RGD:13792537 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132 		JBrowse link
malonate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsf3 acyl-CoA synthetase family member 3 involved_in ISO (PMID:21642549), (PMID:21846720) RGD PMID:21642549 PMID:21846720 NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553 		JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin involved_in ISO
ISS		 (PMID:16899818)
GO_REF:0000024		 RGD
UniProt		 PMID:16899818 GO_REF:0000024 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663 		JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:12140278)		 UniProt
RGD		 PMID:12140278 GO_REF:0000024 GO_REF:0000104 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
oxalate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 involved_in ISO (PMID:21896830) RGD PMID:21896830 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568 		JBrowse link
oxaloacetate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase involved_in ISO
IEA		 (PMID:1371749)
GO_REF:0000107		 RGD
Ensembl		 PMID:1371749 GO_REF:0000107 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Cs citrate synthase IDA RGD PMID:5820645 PMID:938457 PMID:818082 RGD:2306824, RGD:2306828, RGD:2306825 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within IDA
ISO		 (MGI:53641|PMID:4193185) RGD PMID:4193185 PMID:16489927 MGI:53641, RGD:13504861 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within IDA
ISO		 (MGI:53641|PMID:4193185) RGD PMID:4193185 PMID:16489927 MGI:53641, RGD:13504861 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Mdh1 malate dehydrogenase 1 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:17447164 PMID:21873635 RGD:1624966, RGD:13792537 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mdh1b malate dehydrogenase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933 		JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:938457 RGD:2306828 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Nit2 nitrilase family, member 2 involved_in ISO
IBA		 (PMID:22674578)
PMID:21873635		 RGD PMID:22674578 PMID:21873635 RGD:13792537 NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024 		JBrowse link
G Pc pyruvate carboxylase IDA RGD PMID:15507531 PMID:5773282 PMID:6049928 RGD:1601554, RGD:2302972, RGD:2302971 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in IDA
ISO		 (MGI:6119963|PMID:29230018)
PMID:26709450
PMID:30193097
PMID:26322521
(PMID:26792594)
(PMID:30193097)
PMID:31461616		 RGD PMID:26792594 PMID:29230018 PMID:30193097 PMID:16125296 PMID:26709450 More... MGI:6119963, RGD:1601233, RGD:30309918, RGD:13825433, RGD:30309937, RGD:30309906, RGD:2302971, RGD:2302850 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IDA RGD PMID:6049928 RGD:2302971 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO (MGI:5306122|PMID:21757002) RGD PMID:21757002 MGI:5306122 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO (MGI:5306122|PMID:21757002) RGD PMID:21757002 MGI:5306122 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
proline catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Iffo2 intermediate filament family orphan 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,831,503...151,873,075 JBrowse link
G Prodh1 proline dehydrogenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Prodh2 proline dehydrogenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162 		JBrowse link
G Tas1r2 taste 1 receptor member 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,909,648...151,925,345 JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO
IEA		 (PMID:28792876)
GO_REF:0000104		 RGD
UniProt		 PMID:28792876 GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1861934|MGI:1861935 (MGI:3653320|PMID:16697652) RGD PMID:16697652 MGI:3653320 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in ISO (PMID:9291104) RGD PMID:9291104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
quinolinate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Qprt quinolinate phosphoribosyltransferase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:24038671), (PMID:3409840), (PMID:9473669)
(PMID:9473669)
PMID:21873635		 RGD PMID:3409840 PMID:9473669 PMID:24038671 PMID:21873635 RGD:13792537 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
quinolinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:2940338 PMID:21873635 PMID:9870556 PMID:3112306 RGD:2290301, RGD:13792537, RGD:2290370, RGD:2290302 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase IDA RGD PMID:8694849 RGD:2289495 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IDA RGD PMID:19858196 RGD:6484536 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (MGI:4948153|PMID:21490221), (MGI:5562570|PMID:24548853), (MGI:5616960|PMID:25429150) RGD PMID:21490221 PMID:24548853 PMID:25429150 MGI:4948153 MGI:5562570 MGI:5616960 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
succinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA		 MGI:2180159 (MGI:3759189|PMID:12065715)
GO_REF:0000107
PMID:7814412		 RGD
Ensembl		 PMID:12065715 PMID:12871571 PMID:7814412 PMID:12527414 PMID:7262085 GO_REF:0000107 MGI:3759189, RGD:1304407, RGD:632258, RGD:1600514, RGD:1600512 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A involved_in IMP
ISO
ISS		 (PMID:7550341)
GO_REF:0000024		 RGD
UniProt		 PMID:7550341 PMID:16520240 GO_REF:0000024, RGD:2306906 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Sdhaf3 succinate dehydrogenase complex assembly factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:35,143,131...35,160,416
Ensembl chr 4:35,100,506...35,160,749 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B IMP RGD PMID:16520240 RGD:2306906 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta IDA RGD PMID:17403370 RGD:2306915 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha IDA RGD PMID:17403370 RGD:2306915 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta IDA RGD PMID:17403370 RGD:2306915 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    metabolic process 11735
      cellular metabolic process 10655
        organic acid metabolic process 1008
          oxoacid metabolic process 976
            carboxylic acid metabolic process 957
              dicarboxylic acid metabolic process 99
                10-formyltetrahydrofolate metabolic process + 5
                2-oxoglutarate metabolic process + 18
                5,6,7,8-tetrahydromethanopterin metabolic process + 0
                Kdo2-lipid A metabolic process + 0
                actinorhodin metabolic process + 0
                aldaric acid metabolic process + 0
                aspartate metabolic process + 8
                chorismate metabolic process + 0
                diaminopimelate metabolic process + 0
                dicarboxylic acid biosynthetic process + 14
                dicarboxylic acid catabolic process + 14
                dihydrofolate metabolic process + 2
                folic acid metabolic process + 8
                fumarate metabolic process + 3
                gibberellin 12 metabolic process + 0
                glutamate metabolic process + 36
                malate metabolic process 9
                oxalate metabolic process + 1
                oxaloacetate metabolic process + 11
                prephenate(2-) metabolic process + 0
                protocatechuate catabolic process, ortho-cleavage 0
                quinolinate metabolic process + 6
                succinate metabolic process + 7
paths to the root