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Gene: D2hgdh (D-2-hydroxyglutarate dehydrogenase) Rattus norvegicus
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Symbol: D2hgdh
Name: D-2-hydroxyglutarate dehydrogenase
Description: Exhibits (R)-2-hydroxyglutarate dehydrogenase activity. Involved in several processes, including response to cobalt ion; response to manganese ion; and response to zinc ion. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in D-2-hydroxyglutaric aciduria 1. Orthologous to human D2HGDH (D-2-hydroxyglutarate dehydrogenase); INTERACTS WITH (+)-schisandrin B; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: D-2-hydroxyglutarate dehydrogenase, mitochondrial; LOC301624; RGD1307976; similar to AI325464 protein
Orthologs:
Homo sapiens (human) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
Canis lupus familiaris (dog) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)
Sus scrofa (pig) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.09100,956,570 - 100,974,393 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,956,477 - 100,974,551 (+)Ensembl
Rnor_5.09100,609,534 - 100,627,445 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4993,100,369 - 93,119,170 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1993,306,221 - 93,323,618 (+)NCBI
Celera991,884,977 - 91,901,371 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on D2hgdh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307976
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.