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ONTOLOGY REPORT - ANNOTATIONS


Term:voltage-gated chloride channel activity
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Accession:GO:0005247 term browser browse the term
Definition:Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms:exact_synonym: voltage-dependent chloride channel activity
 xref: reactome:R-HSA-2744228 "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region"



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voltage-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 enables ISO (PMID:22634729) RGD PMID:22634729 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Ano6 anoctamin 6 enables ISO (PMID:22006324) RGD PMID:22006324 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Clcn1 chloride voltage-gated channel 1 enables IDA
IEA
ISO
IBA
GO_REF:0000104
(PMID:22521272), (PMID:26007199), (PMID:26502825)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:22521272 PMID:26007199 PMID:26502825 PMID:1659664 GO_REF:0000033 GO_REF:0000104, RGD:727583 NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984
JBrowse link
G Clcn2 chloride voltage-gated channel 2 enables IDA
IEA
IBA
ISO
IMP
GO_REF:0000002
GO_REF:0000033
MGI:2183262 (PMID:11976342)
(PMID:16155254), (PMID:29403011), (PMID:36964785)
PMID:8816717
PMID:1334533
InterPro
GO_Central
RGD
PMID:11976342 PMID:16155254 PMID:29403011 PMID:36964785 PMID:1311421 More... GO_REF:0000002 GO_REF:0000033, RGD:69809, RGD:405650388, RGD:405650350 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
JBrowse link
G Clcn3 chloride voltage-gated channel 3 enables IDA
IEA
IBA
GO_REF:0000104
PMID:10915634
GO_REF:0000033
UniProt
GO_Central
RGD
PMID:10915634 PMID:10915634 GO_REF:0000033 GO_REF:0000104, RGD:628537, RGD:628537 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clcn4 chloride voltage-gated channel 4 enables IEA
IBA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clcn5 chloride voltage-gated channel 5 enables IDA
ISO
IEA
IBA
(PMID:8559248)
GO_REF:0000104
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:8559248 PMID:8626585 GO_REF:0000033 GO_REF:0000104, RGD:727659 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264
JBrowse link
G Clcn6 chloride voltage-gated channel 6 enables ISO (PMID:20466723) RGD PMID:20466723 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clcn7 chloride voltage-gated channel 7 enables IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130
JBrowse link
G Clcnka chloride voltage-gated channel Ka enables IEA
TAS
IBA
GO_REF:0000104
PMID:8041726
GO_REF:0000033
UniProt
GO_Central
PMID:8041726 GO_REF:0000033 GO_REF:0000104, RGD:632474 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Clcnkb chloride voltage-gated channel Kb enables IEA
TAS
IBA
GO_REF:0000104
PMID:8041726
GO_REF:0000033
UniProt
GO_Central
PMID:8041726 GO_REF:0000033 GO_REF:0000104, RGD:632474 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Clic1 chloride intracellular channel 1 TAS RGD PMID:15190104 RGD:1304001 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Tmc4 transmembrane channel-like 4 enables ISS
ISO
GO_REF:0000024
(PMID:34429071), (PMID:34468713)
UniProt
RGD
PMID:34429071 PMID:34468713 GO_REF:0000024 NCBI chr 1:65,539,777...65,551,683
Ensembl chr 1:65,539,721...65,551,677
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 762
          monoatomic ion channel activity 451
            monoatomic anion channel activity 102
              chloride channel activity 81
                voltage-gated chloride channel activity 13
                  organellar voltage-gated chloride channel activity 0
Path 2
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        passive transmembrane transporter activity 511
          channel activity 511
            gated channel activity 334
              voltage-gated channel activity 190
                voltage-gated monoatomic ion channel activity 186
                  voltage-gated monoatomic anion channel activity 23
                    voltage-gated chloride channel activity 13
                      organellar voltage-gated chloride channel activity 0
paths to the root