CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: fluoxastrobin
Accession: CHEBI:83253
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Definition: An oxime O-ether that is the O-methyl oxime of (2-{[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone. A fungicide used for disease control of potatoes and a wide range of vegetables.
Synonyms: exact_synonym: (E)-1-(2-{[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine
related_synonym: (1E)-(2-((6-(2-chlorophenoxy)-5-fluoro-4-pyrimidinyl)oxy)phenyl)(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone O-methyloxime; Formula=C21H16ClFN4O5; InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+; InChIKey=UFEODZBUAFNAEU-NLRVBDNBSA-N; SMILES=CO\\N=C(\\C1=NOCCO1)c1ccccc1Oc1ncnc(Oc2ccccc2Cl)c1F
xref: AGR:IND500677369; CAS:361377-29-9
xref_mesh: MESH:C550006
xref: PPDB:340; Patent:EP2319308; Patent:NZ554381; Pesticides:fluoxastrobin; Reaxys:11322454
G
Ar
androgen receptor
multiple interactions
ISO
fluoxastrobin inhibits the reaction [Metribolone results in increased activity of AR protein]
CTD
PMID:30818834
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
G
Esr1
estrogen receptor 1 (alpha)
multiple interactions
ISO
fluoxastrobin inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
CTD
PMID:30818834
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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Esr2
estrogen receptor 2 (beta)
multiple interactions
ISO
fluoxastrobin inhibits the reaction [Estradiol results in increased activity of ESR2 protein]
CTD
PMID:30818834
NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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Esrra
estrogen related receptor, alpha
multiple interactions
ISO
fluoxastrobin inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]; fluoxastrobin inhibits the reaction [XCT790 results in decreased activity of ESRRA protein]
CTD
PMID:30818834
NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
G
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
decreases expression
ISO
fluoxastrobin results in decreased expression of IDH3A mRNA
CTD
PMID:30818834
NCBI chr 9:54,493,795...54,511,946
Ensembl chr 9:54,493,618...54,511,945
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
increases activity
ISO
fluoxastrobin results in increased activity of NFE2L2 protein
CTD
PMID:30818834
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
G
Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions
ISO
fluoxastrobin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
CTD
PMID:30818834
NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
G
Pgr
progesterone receptor
multiple interactions
ISO
fluoxastrobin inhibits the reaction [Promegestone results in increased activity of PGR protein]
CTD
PMID:30818834
NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
G
Pparg
peroxisome proliferator activated receptor gamma
multiple interactions
ISO
fluoxastrobin inhibits the reaction [Rosiglitazone results in increased activity of PPARG protein]
CTD
PMID:30818834
NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
G
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
multiple interactions
ISO
fluoxastrobin inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]
CTD
PMID:30818834
NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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