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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,4-di-tert-butylphenol
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Accession:CHEBI:89188 term browser browse the term
Definition:A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 4.
Synonyms:related_synonym: 1-Hydroxy-2,4-di-tert-butylbenzene;   2,4-Bis(1,1-dimethylethyl)phenol;   2,4-Bis(tert-butyl)phenol;   2,4-Di-t-Butylphenol;   2,4-Tert-butylphenol;   Formula=C14H22O;   InChI=1S/C14H22O/c1-13(2,3)10-7-8-12(15)11(9-10)14(4,5)6/h7-9,15H,1-6H3;   InChIKey=ICKWICRCANNIBI-UHFFFAOYSA-N;   SMILES=OC1=CC=C(C(C)(C)C)C=C1C(C)(C)C
 xref: CAS:96-76-4;   HMDB:HMDB0013816
 xref_mesh: MESH:C056559
 xref: PMID:16595909;   PMID:22020168;   PMID:23450232;   PMID:24074359;   PMID:24934765;   PMID:25641715;   PMID:27107984;   PMID:27524650;   Reaxys:1910383


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2,4-di-tert-butylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrrg estrogen-related receptor gamma increases activity ISO 2,4-di-tert-butylphenol results in increased activity of ESRRG protein CTD PMID:31127318 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO 2,4-di-tert-butylphenol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2] results in increased expression of KEAP1 mRNA CTD PMID:36682590 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Meox1 mesenchyme homeobox 1 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in decreased expression of MEOX1 mRNA CTD PMID:36682590 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Nanog Nanog homeobox multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in increased expression of NANOG mRNA CTD PMID:36682590 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Pax3 paired box 3 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in decreased expression of PAX3 mRNA CTD PMID:36682590 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Pax9 paired box 9 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2] results in decreased expression of PAX9 mRNA CTD PMID:36682590 NCBI chr 6:74,186,749...74,203,508
Ensembl chr 6:74,182,568...74,203,506 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in increased expression of POU5F1 mRNA CTD PMID:36682590 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of RUNX2 mRNA CTD PMID:36682590 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SP7 mRNA CTD PMID:36682590 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA CTD PMID:36682590 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tbx6 T-box transcription factor 6 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in decreased expression of TBX6 mRNA CTD PMID:36682590 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO 2,4-di-tert-butylphenol results in increased activity of TRPA1 protein CTD PMID:21591660 PMID:29658714 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity ISO 2,4-di-tert-butylphenol results in increased activity of TRPV3 protein CTD PMID:29658714 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      chemical role 19489
        antioxidant 16167
          2,4-di-tert-butylphenol 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    main group molecular entity 19806
                      s-block molecular entity 19641
                        hydrogen molecular entity 19622
                          hydrides 19150
                            organic hydride 18682
                              organic fundamental parent 18682
                                hydrocarbon 18432
                                  cyclic hydrocarbon 17238
                                    monocyclic hydrocarbon 6162
                                      annulene 5815
                                        aromatic annulene 5818
                                          benzene 5818
                                            alkylbenzene 3536
                                              2,4-di-tert-butylphenol 14
paths to the root