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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1-methyltryptophan
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Accession:CHEBI:72821 term browser browse the term
Definition:A tryptophan derivative that is tryptophan carrying a single methyl substituent at position 1 on the indole.
Synonyms:related_synonym: 1-methyl-DL-tryptophan;   Formula=C12H14N2O2;   InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16);   InChIKey=ZADWXFSZEAPBJS-UHFFFAOYSA-N;   N-methyl-DL-tryptophan;   N-methyltryptophan;   SMILES=Cn1cc(CC(N)C(O)=O)c2ccccc12
 xref: CAS:26988-72-7
 xref_mesh: MESH:C525396
 xref: PMID:18195714;   PMID:19307751;   PMID:19461669;   PMID:20424892;   PMID:20435158;   PMID:21526853;   PMID:22068654;   PMID:22131334;   PMID:22184722;   PMID:22294267;   PMID:22320717;   PMID:22504306;   PMID:22527253;   PMID:22594922;   PMID:22615663;   Reaxys:20071;   Wikipedia:1-Methyltryptophan


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1-methyltryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein] CTD PMID:35687267 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein] CTD PMID:35687267 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein] CTD PMID:35687267 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein] CTD PMID:35687267 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein] CTD PMID:35687267 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 decreases activity ISO 1-methyltryptophan results in decreased activity of IDO2 protein CTD PMID:32289347 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein] CTD PMID:35687267 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein] CTD PMID:35687267 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein] CTD PMID:35687267 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of TDO2 protein] CTD PMID:35687267 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
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  CHEBI ontology 19844
    role 19820
      application 19663
        pharmaceutical 19504
          drug 19504
            antineoplastic agent 17765
              1-methyltryptophan 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    main group molecular entity 19792
                      s-block molecular entity 19626
                        hydrogen molecular entity 19613
                          hydrides 19115
                            inorganic hydride 18121
                              pnictogen hydride 18110
                                nitrogen hydride 18017
                                  azane 17823
                                    ammonia 17797
                                      organic amino compound 17822
                                        amino acid 15956
                                          polar amino acid 11703
                                            tryptophan 36
                                              tryptophan derivative 24
                                                1-methyltryptophan 10
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