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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Htris
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Accession:CHEBI:46097 term browser browse the term
Definition:A triol that has formula C4H12NO3.
Synonyms:exact_synonym: 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium
 related_synonym: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL;   Formula=C4H12NO3;   InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2/p+1;   InChIKey=LENZDBCJOHFCAS-UHFFFAOYSA-O;   SMILES=[NH3+]C(CO)(CO)CO
 alt_id: CHEBI:37213;   CHEBI:46096
 xref: Gmelin:1450818;   PDBeChem:TRS
 cyclic_relationship: is_conjugate_acid_of CHEBI:9754


show annotations for term's descendants           Sort by:
ketorolac tromethamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP Ketorolac Tromethamine results in decreased localization of and results in decreased activity of AANAT protein CTD PMID:37348669 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801 		JBrowse link
G Cat catalase multiple interactions
increases activity		 EXP Melatonin inhibits the reaction [Ketorolac Tromethamine results in increased activity of CAT protein] CTD PMID:37348669 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ereg epiregulin increases expression ISO Ketorolac Tromethamine results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP Ketorolac Tromethamine results in decreased activity of GPX1 protein CTD PMID:37348669 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP Ketorolac Tromethamine results in increased activity of GSR protein CTD PMID:37348669 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Il24 interleukin 24 increases expression ISO Ketorolac Tromethamine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Maoa monoamine oxidase A multiple interactions
increases activity		 EXP Melatonin inhibits the reaction [Ketorolac Tromethamine results in increased activity of MAOA protein] CTD PMID:37348669 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mtnr1a melatonin receptor 1A increases localization EXP Ketorolac Tromethamine results in increased localization of MTNR1A protein CTD PMID:37348669 NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Ketorolac Tromethamine results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Ketorolac Tromethamine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP Ketorolac Tromethamine results in decreased activity of SOD1 protein CTD PMID:37348669 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases activity EXP Ketorolac Tromethamine results in decreased activity of SOD2 protein CTD PMID:37348669 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      chemical role 19524
        buffer 54
          Htris 12
            carboprost tromethamine 0
            ketorolac tromethamine 12
            tris acetate 0
            tris maleate 0
            tris phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      p-block molecular entity 19865
                        chalcogen molecular entity 19614
                          oxygen molecular entity 19586
                            hydroxides 19389
                              organic hydroxy compound 18997
                                polyol 11714
                                  triol 7002
                                    Htris 12
                                      carboprost tromethamine 0
                                      ketorolac tromethamine 12
                                      tris acetate 0
                                      tris maleate 0
                                      tris phosphate 0
paths to the root