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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Bisphenol A glycidylmethacrylate
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Accession:CHEBI:34580 term browser browse the term
Definition:A diarylmethane that has formula C29H36O8.
Synonyms:related_synonym: 2,2-Bis[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]propane;   Bis-GMA;   Bisphenol A diglycidyl methacrylate;   Formula=C29H36O8;   InChI=1S/C29H36O8/c1-19(2)27(32)36-17-23(30)15-34-25-11-7-21(8-12-25)29(5,6)22-9-13-26(14-10-22)35-16-24(31)18-37-28(33)20(3)4/h7-14,23-24,30-31H,1,3,15-18H2,2,4-6H3;   InChIKey=AMFGWXWBFGVCKG-UHFFFAOYSA-N;   SMILES=CC(=C)C(=O)OCC(O)COc1ccc(cc1)C(C)(C)c1ccc(OCC(O)COC(=O)C(C)=C)cc1
 xref: CAS:1565-94-2;   KEGG:C14511
 xref_mesh: MESH:D017438


show annotations for term's descendants           Sort by:
Bisphenol A glycidylmethacrylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions
increases activity		 EXP wogonin inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP3 protein] CTD PMID:26756871 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions		 EXP Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein
wogonin inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein]		 CTD PMID:26756871 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES1 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES2 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES3 mRNA]; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of HMOX1 mRNA] CTD PMID:20673999 PMID:21951919 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccnb1 cyclin B1 decreases expression
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA; Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 protein
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA]		 CTD PMID:20673999 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C mRNA; Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C protein
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDC25C mRNA]		 CTD PMID:20673999 NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586 		JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases expression
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 mRNA; Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 protein
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CDK1 mRNA]		 CTD PMID:20673999 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression		 ISO CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES1 mRNA] CTD PMID:21951919 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of CES2 mRNA
[Loperamide results in decreased activity of CES2 protein] which results in increased susceptibility to Bisphenol A-Glycidyl Methacrylate; CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES2 mRNA]		 CTD PMID:21951919 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Ces3b carboxylesterase 3B increases expression
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of CES3 mRNA
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES3 mRNA]		 CTD PMID:21951919 NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of CXCL8 mRNA CTD PMID:27965148 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases activity
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in increased activity of ESR1 protein
[Bisphenol A-Glycidyl Methacrylate co-treated with 2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate] results in increased activity of ESR1 protein		 CTD PMID:11145352 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO Bisphenol A-Glycidyl Methacrylate results in increased expression of HMOX1 mRNA
CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of HMOX1 mRNA]		 CTD PMID:20673999 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate co-treated with Bisphenol A-Glycidyl Methacrylate co-treated with Benzoyl Peroxide] results in increased expression of PTGS2 mRNA; [2,2-di(4-methacryloxyphenyl)propane co-treated with triethylene glycol dimethacrylate co-treated with Bisphenol A-Glycidyl Methacrylate co-treated with Benzoyl Peroxide] results in increased expression of PTGS2 protein CTD PMID:15264312 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Bisphenol A-Glycidyl Methacrylate co-treated with triethylene glycol dimethacrylate] results in increased expression of TNF mRNA CTD PMID:17140868 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22182
    chemical entity 22181
      group 22077
        polyatomic entity 22077
          molecule 21676
            cyclic compound 21262
              organic cyclic compound 21261
                organic aromatic compound 20748
                  diarylmethane 9609
                    Bisphenol A glycidylmethacrylate 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 22182
    subatomic particle 22174
      composite particle 22174
        hadron 22174
          baryon 22174
            nucleon 22174
              atomic nucleus 22174
                atom 22174
                  main group element atom 22108
                    p-block element atom 22108
                      p-block molecular entity 22108
                        carbon group molecular entity 21909
                          organic molecular entity 21835
                            organic molecule 21652
                              organic cyclic compound 21261
                                organic aromatic compound 20748
                                  diarylmethane 9609
                                    Bisphenol A glycidylmethacrylate 15
paths to the root