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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alpha-amino-acid cation
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Accession:CHEBI:33719 term browser browse the term
Synonyms:related_synonym: alpha-amino acid cations
 cyclic_relationship: is_conjugate_acid_of CHEBI:33704


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L-proline betaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein] CTD PMID:32417162 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS5 protein] CTD PMID:32417162 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; stachydrine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS5 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:32417162 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] CTD PMID:32417162 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein] CTD PMID:32417162 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:32417162 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein] CTD PMID:32417162 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:32417162 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:32417162 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein] CTD PMID:32417162 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO stachydrine inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:32417162 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      molecular entity 19839
        ion 16708
          cation 16522
            organic cation 8916
              amino-acid cation 11
                alpha-amino-acid cation 11
                  (2R,4S)-2,4-diazaniumylpentanoate 0
                  (2R,5S)-2,5-diammoniohexanoate 0
                  (2S,3R)-capreomycidine(1+) 0
                  (3S)-3-hydroxy-L-arginine(1+) 0
                  (3S)-3-hydroxy-L-enduracididine(1+) 0
                  (3S)-3-hydroxy-L-lysine(1+) + 0
                  (3S)-3-hydroxy-L-ornithine(1+) 0
                  (4-\{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl\}furan-2-yl)methanamine(1+) 0
                  (4R)-4-hydroxy-L-lysine(1+) 0
                  1-carboxyheptan-1-aminium 0
                  3-(3,4-dioxidopyridinium-1-yl)-L-alanine(1-) 0
                  3-ammonio-L-alanine 0
                  3-ammonio-L-alanine(1+) 0
                  3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine zwitterion + 0
                  4-chloro-L-lysinium 0
                  4-hydroxy-L-lysine(1+) + 0
                  5-hydroxylysinium 0
                  L-2,4-diazaniumylbutyrate 0
                  L-canavanine(1+) + 0
                  L-enduracididine(1+) 0
                  L-pyrrolysinium + 0
                  N(5)-[(hydroxyamino)(imino)methyl]-L-ornithinium(1+) 0
                  N(6),N(6),N(6)-trimethyl-L-lysine + 0
                  N(6),N(6),N(6)-trimethyl-L-lysine zwitterion + 0
                  N(6)-acetimidoyl-L-lysinium(2+) + 0
                  N(6)-methyl-L-lysinium(1+) 0
                  Se-methyl-L-selenomethionine(1+) 0
                  Se-methylselenocysteinium + 0
                  Se-methylselenomethionine + 0
                  alaninium + 0
                  alpha-amino-acid radical cation + 0
                  argininium(1+) + 0
                  argininium(2+) + 0
                  asparaginium + 0
                  carboxynorspermidine(2+) 0
                  carboxyspermidine(2+) 0
                  cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) 0
                  cyclo(L-arginyl-L-dehydrotyrosyl)(+1) + 0
                  cyclo(L-arginyl-L-tyrosyl)(+1) 0
                  cysteinium + 0
                  dimethylargininium(1+) + 0
                  ergothioneine(1+) 0
                  erythro-5-hydroxy-L-lysinium(1+) 0
                  glutaminium + 0
                  glycinium + 0
                  histidinium(1+) + 0
                  histidinium(2+) + 0
                  isoleucinium + 0
                  leucinium + 0
                  lysinium(1+) + 0
                  lysinium(2+) + 0
                  methioninium + 0
                  ornithinium(1+) + 0
                  ornithinium(2+) + 0
                  phenylalaninium + 0
                  prolinium + 11
                  sarcosinium 0
                  selenocysteinium + 0
                  serinium + 0
                  threoninium + 0
                  tryptophanium + 0
                  tyrosinium + 0
                  valinium + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon group molecular entity 19737
                          organic molecular entity 19733
                            organic ion 9866
                              organic cation 8916
                                amino-acid cation 11
                                  alpha-amino-acid cation 11
                                    (2R,4S)-2,4-diazaniumylpentanoate 0
                                    (2R,5S)-2,5-diammoniohexanoate 0
                                    (2S,3R)-capreomycidine(1+) 0
                                    (3S)-3-hydroxy-L-arginine(1+) 0
                                    (3S)-3-hydroxy-L-enduracididine(1+) 0
                                    (3S)-3-hydroxy-L-lysine(1+) + 0
                                    (3S)-3-hydroxy-L-ornithine(1+) 0
                                    (4-\{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl\}furan-2-yl)methanamine(1+) 0
                                    (4R)-4-hydroxy-L-lysine(1+) 0
                                    1-carboxyheptan-1-aminium 0
                                    3-(3,4-dioxidopyridinium-1-yl)-L-alanine(1-) 0
                                    3-ammonio-L-alanine 0
                                    3-ammonio-L-alanine(1+) 0
                                    3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine zwitterion + 0
                                    4-chloro-L-lysinium 0
                                    4-hydroxy-L-lysine(1+) + 0
                                    5-hydroxylysinium 0
                                    L-2,4-diazaniumylbutyrate 0
                                    L-canavanine(1+) + 0
                                    L-enduracididine(1+) 0
                                    L-pyrrolysinium + 0
                                    N(5)-[(hydroxyamino)(imino)methyl]-L-ornithinium(1+) 0
                                    N(6),N(6),N(6)-trimethyl-L-lysine + 0
                                    N(6),N(6),N(6)-trimethyl-L-lysine zwitterion + 0
                                    N(6)-acetimidoyl-L-lysinium(2+) + 0
                                    N(6)-methyl-L-lysinium(1+) 0
                                    Se-methyl-L-selenomethionine(1+) 0
                                    Se-methylselenocysteinium + 0
                                    Se-methylselenomethionine + 0
                                    alaninium + 0
                                    alpha-amino-acid radical cation + 0
                                    argininium(1+) + 0
                                    argininium(2+) + 0
                                    asparaginium + 0
                                    carboxynorspermidine(2+) 0
                                    carboxyspermidine(2+) 0
                                    cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) 0
                                    cyclo(L-arginyl-L-dehydrotyrosyl)(+1) + 0
                                    cyclo(L-arginyl-L-tyrosyl)(+1) 0
                                    cysteinium + 0
                                    dimethylargininium(1+) + 0
                                    ergothioneine(1+) 0
                                    erythro-5-hydroxy-L-lysinium(1+) 0
                                    glutaminium + 0
                                    glycinium + 0
                                    histidinium(1+) + 0
                                    histidinium(2+) + 0
                                    isoleucinium + 0
                                    leucinium + 0
                                    lysinium(1+) + 0
                                    lysinium(2+) + 0
                                    methioninium + 0
                                    ornithinium(1+) + 0
                                    ornithinium(2+) + 0
                                    phenylalaninium + 0
                                    prolinium + 11
                                    sarcosinium 0
                                    selenocysteinium + 0
                                    serinium + 0
                                    threoninium + 0
                                    tryptophanium + 0
                                    tyrosinium + 0
                                    valinium + 0
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