| 3770 | Star | steroidogenic acute regulatory protein | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN bile acid biosynthetic process; cellular response to alkaloid; cellular response to antibiotic; PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; estra diol biosynthetic pathway; ASSOCIATED WITH Cardiomegaly; Disorders of Environmental Origin; Experimental Diabetes Mellitus; FOUND IN mitochondrial crista; neuronal cell body; mitochondrial outer membrane (ortholog); INTERACTS WITH (+)-pilocarpine; (-)-citrinin; (25R)-cholest-5-ene-3beta,26-diol | 16 | 72969824 | 72974447 | Rat | 846 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549768 | Stard3 | StAR-related lipid transfer domain containing 3 | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cholesterol transport (ortholog); progesterone biosynthetic process (ortholog); vesicle tethering to endoplasmic reticulum (ortholog); A SSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-endosome membrane contact site (ortholog); endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; finasteride | 10 | 83853622 | 83876162 | Rat | 59 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309475 | Stard4 | StAR-related lipid transfer domain containing 4 | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cholesterol import (ortholog); cholesterol transport involved in cholesterol storage (ortholog); intracellular cholesterol transport (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 17beta-estradiol | 18 | 25088831 | 25104172 | Rat | 187 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1561783 | Stard5 | StAR-related lipid transfer domain containing 5 | ENCODES a protein that exhibits bile acid binding (ortholog); cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cholesterol import (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 147015304 | 147025170 | Rat | 112 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359639 | Stard6 | StAR-related lipid transfer domain containing 6 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN lipid transport (inferred); INTERACTS WITH (+)-pilocarpine; 2,2',5,5'-tetrachlorobiphenyl; acetamide | 18 | 66365526 | 66393439 | Rat | 32 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307613 | Stard7 | StAR-related lipid transfer domain containing 7 | ENCODES a protein that exhibits molecular carrier activity (ortholog); phosphatidylcholine transfer activity (ortholog); INVOLVED IN establishment of skin barrier (ortholog); inflammatory response (ortholog); intermembrane phospholipid transfer (ortholog); ASSOCIATED WITH familial adult myoclonic ep ilepsy 2 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial intermembrane space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; flutamide | 3 | 134935602 | 134969140 | Rat | 92 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1560770 | Stard8 | StAR-related lipid transfer domain containing 8 | ENCODES a protein that exhibits GTPase activator activity (inferred); lipid binding (inferred); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamin e; 6-propyl-2-thiouracil | X | 68119276 | 68236247 | Rat | 68 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1593360 | Stard9 | StAR-related lipid transfer domain containing 9 | ENCODES a protein that exhibits microtubule binding (ortholog); microtubule motor activity (ortholog); INVOLVED IN spindle assembly (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); bipolar disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN centriole (ortholog); cyto plasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; azoxystrobin | 3 | 128034866 | 128150493 | Rat | 85 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1306548 | Stard10 | StAR-related lipid transfer domain containing 10 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN bile acid secretion (ortholog); positive regulation of peroxisome proliferator activated receptor signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); intercellular canaliculus (ortholog); membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 165130408 | 165159134 | Rat | 125 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1564816 | Stard13 | StAR-related lipid transfer domain containing 13 | ENCODES a protein that exhibits GTPase activator activity (inferred); lipid binding (inferred); INVOLVED IN endothelial cell migration (ortholog); endothelial tube lumen extension (ortholog); negative regulation of cell migration involved in sprouting angiogenesis (ortholog); ASSOCIATED WITH COVID-1 9 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); lipid droplet (inferred); membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 12 | 5401878 | 5797937 | Rat | 136 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561043 | Tut1 | terminal uridylyl transferase 1, U6 snRNA-specific | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme-substrate adaptor activity (ortholog); mRNA 3'-UTR binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); histone mRNA catabolic process (ortholog); mRNA 3'-end proc essing (ortholog); FOUND IN mRNA cleavage and polyadenylation specificity factor complex (ortholog); nuclear speck (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A | 1 | 215277802 | 215288869 | Rat | 113 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3276 | Pctp | phosphatidylcholine transfer protein | ENCODES a protein that exhibits phosphatidylcholine binding (ortholog); phosphatidylcholine transporter activity (ortholog); INVOLVED IN cholesterol metabolic process (ortholog); negative regulation of cold-induced thermogenesis (ortholog); phospholipid transport (ortholog); FOUND IN cytosol (orthol og); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 75305999 | 75351919 | Rat | 169 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 68416 | Dlc1 | DLC1 Rho GTPase activating protein | ENCODES a protein that exhibits GTPase activator activity; phospholipase binding; phospholipase C activator activity; INVOLVED IN cellular response to insulin stimulus; actin cytoskeleton organization (ortholog); focal adhesion assembly (ortholog); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pa thway; ASSOCIATED WITH amenorrhea (ortholog); colon carcinoma (ortholog); colorectal cancer (ortholog); FOUND IN actin filament; focal adhesion; stress fiber; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 16 | 61954177 | 62374819 | Rat | 213 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1308063 | Tmc3 | transmembrane channel-like 3 | INVOLVED IN monoatomic ion transmembrane transport (inferred); ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamide | 1 | 146961518 | 147009742 | Rat | 27 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1308633 | Stard3nl | STARD3 N-terminal like | ENCODES a protein that exhibits cholesterol binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN vesicle tethering to endoplasmic reticulum (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-endosome membrane contact site (ortholog); endoso me (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 17 | 50278859 | 50312864 | Rat | 75 | symbol , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 708493 | Abra | actin-binding Rho activating protein | ENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of Rho protein signal transduction (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); FOUND IN sarcomere; actin cytoskeleton (ortholog); myofibril (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-deoxy-D-glucose; acrylamide | 7 | 74855008 | 74859076 | Rat | 74 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 71095 | Cacng2 | calcium voltage-gated channel auxiliary subunit gamma 2 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; voltage-gated calcium channel activity (ortholog); INVOLVED IN eye blink reflex; positive regulation of AMPA receptor activity; positive regulation of protein localization to basolateral plasma membrane; PARTICIPATES IN calcium/c almodulin dependent kinase 2 signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; ASSOCIATED WITH childhood absence epilepsy; autosomal dominant intellectual developmental disorder 10 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN AMPA glutamate receptor complex; cell surface; cerebellar mossy fiber; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 7 | 111451605 | 111579071 | Rat | 152 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 152999024 | Aif1tm(EGFP)Apps | allograft inflammatory factor 1; target mutant 1,Apps | Applied StemCell, Inc (Milpitas, CA) was contracted to generate the Iba1-EGFP knock-in rat model using CRISPR/Cas9 technology in the Sprague Dawley rat strain. The donor construct inserted consisted of the EGFP coding sequence (minus the first ATG), followed by the 22 amino acid sequence of the porc ine teschovirus-1 2A (P2A) self-cleaving peptide, and then the first exon of the rat Iba1 gene immediately downstream of the translational start site. Guide RNA with the following sequence: 5'- TACCCTGCAAATCCTTGCTCTGG-3' targeting the Iba1 gene just downstream of the translational start site were used. | | | | Rat | | description | gene, allele |
| 735088 | Flcn | folliculin | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme inhibitor activity (ortholog); GTPase activator activity (ortholog); INVOLVED IN cell-cell junction assembly (ortholog); cellular response to amino acid starvation (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; renal cell carcinoma pathway; ASSOCIATED WITH embryonic lethality; prenatal lethality; ASSOCIATED WITH renal cell carcinoma; Birt-Hogg-Dube syndrome (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); FOUND IN cell-cell contact zone (ortholog); centrosome (ortholog); cilium (ortholog); INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 45088164 | 45107581 | Rat | 331 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311944 | Itfg2 | integrin alpha FG-GAP repeat containing 2 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); germinal center B cell differentiation (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog ); FOUND IN cytosol (ortholog); KICSTOR complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 4 | 163371125 | 163384676 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565498 | Kics2 | KICSTOR subunit 2 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); negative regulation of TORC1 signaling (ortholog); ASSOCIATED WITH autosomal recessive intellectual devel opmental disorder 83 (ortholog); polycystic ovary syndrome (ortholog); FOUND IN KICSTOR complex (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 7 | 59169703 | 59182974 | Rat | 61 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310341 | Kptn | kaptin (actin binding protein) | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); negative regulation of TORC1 signaling (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 41 (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN filamentous actin (ortholog); KICSTOR complex (ortholog); lamellipodium (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; cadmium dichloride | 1 | 85936922 | 85937716 | Rat | 41 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 7489012 | Mir1199 | microRNA 1199 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 19 | 41045337 | 41045456 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 9685073 | Mir1297 | microRNA 1297 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 15 | 63257431 | 63257504 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398603 | Mir190a-2 | microRNA mir-190a-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398599 | Mir196b-2 | microRNA mir-196b-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888545 | Mir291b | microRNA 291b | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 1 | 74879181 | 74879288 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398586 | Mir29b-3 | microRNA mir-29b-3 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489041 | Mir3072 | microRNA 3072 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 6 | 134584566 | 134584676 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398585 | Mir3084a-2 | microRNA mir-3084a-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398595 | Mir3084a-4 | microRNA mir-3084a-4 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 6 | 93551123 | 93551191 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398593 | Mir322-2 | microRNA mir-322-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888565 | Mir344a-2 | microRNA 344a-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 1 | 124655022 | 124655128 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398575 | Mir344b-2 | microRNA mir-344b-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 1 | 124028505 | 124028575 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398600 | Mir344b-3 | microRNA mir-344b-3 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 1 | 124044536 | 124044606 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489017 | Mir344g | microRNA 344g | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 1 | 124754942 | 124755020 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489023 | Mir344i | microRNA 344i | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 1 | 124838110 | 124838208 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398581 | Mir350-2 | microRNA mir-350-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888563 | Mir3541 | microRNA 3541 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 2 | 176878607 | 176878710 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 15039316 | Mir3542-2 | microRNA mir-3542-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna |
| 14398589 | Mir3543-2 | microRNA mir-3543-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888562 | Mir3544 | microRNA 3544 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 6 | 134321154 | 134321241 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888561 | Mir3547 | microRNA 3547 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 10 | 14766769 | 14766878 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888608 | Mir3548 | microRNA 3548 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 5 | 171930704 | 171930823 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888555 | Mir3550 | microRNA 3550 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 19 | 40133492 | 40133605 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888605 | Mir3554 | microRNA 3554 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 5 | 108714843 | 108714960 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888606 | Mir3556b | microRNA 3556b | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 13 | 109099351 | 109099457 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398597 | Mir3556b-2 | microRNA mir-3556b-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888554 | Mir3566 | microRNA 3566 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 17 | 23721811 | 23721919 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888591 | Mir3569 | microRNA 3569 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 1 | 94969059 | 94969134 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888558 | Mir3570 | microRNA 3570 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 13 | 52037048 | 52037164 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888589 | Mir3572 | microRNA 3572 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 1 | 74476425 | 74476532 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888587 | Mir3574 | microRNA 3574 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 1 | 205755917 | 205756034 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888590 | Mir3575 | microRNA 3575 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 4 | 159209938 | 159210052 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888583 | Mir3579 | microRNA 3579 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 6 | 134546218 | 134546330 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 15039307 | Mir3584-2 | microRNA mir-3584-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna |
| 4888577 | Mir3587 | microRNA 3587 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 4 | 60618307 | 60618369 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888571 | Mir3589 | microRNA 3589 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | X | 143778757 | 143778868 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888533 | Mir3595 | microRNA 3595 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 6 | 134559353 | 134559472 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888582 | Mir3596b | microRNA 3596b | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 17 | 16322261 | 16322355 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888599 | Mir3597-1 | microRNA 3597-1 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 2 | 175974962 | 175975069 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888542 | Mir3597-2 | microRNA 3597-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 2 | 15933279 | 15933396 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 4888559 | Mir3597-3 | microRNA 3597-3 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq] | 1 | 142849389 | 142849503 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398578 | Mir503-2 | microRNA mir-503-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398584 | Mir542-2 | microRNA mir-542-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398598 | Mir542-3 | microRNA mir-542-3 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489025 | Mir6316 | microRNA 6316 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 1 | 266506305 | 266506405 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398582 | Mir6317-2 | microRNA mir-6317-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 14398580 | Mir6319-2 | microRNA mir-6319-2 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7488975 | Mir6320 | microRNA 6320 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 15 | 44668612 | 44668732 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489014 | Mir6322 | microRNA 6322 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 12 | 29416304 | 29416422 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489032 | Mir6323 | microRNA 6323 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 11 | 94556447 | 94556551 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489031 | Mir6330 | microRNA 6330 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 8 | 114663698 | 114663836 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489021 | Mir6334 | microRNA 6334 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 3 | 164343325 | 164343423 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 15039315 | Mir679 | microRNA mir-679 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | | | | Rat | | description | gene, ncrna |
| 14398579 | Mir709 | microRNA mir-709 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 19 | 40977572 | 40977664 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 7489046 | Mir7578 | microRNA 7578 | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primar y transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] | 3 | 31176150 | 31176231 | Rat | | description | gene, ncrna, PROVISIONAL [RefSeq] |
| 1303019 | Rpl17 | ribosomal protein L17 | ENCODES a protein that exhibits large ribosomal subunit rRNA binding; structural constituent of ribosome (ortholog); INVOLVED IN cellular response to amino acid starvation; positive regulation of G1/S transition of mitotic cell cycle; response to amino acid ... (more) n style='font-weight:700;'>starvation; PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Myocardial Ischemia (ortholog); FOUND IN A band; cytosolic large ribosomal subunit; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 18 | 70856275 | 70859388 | Rat | 157 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 619805 | Rragb | Ras-related GTP binding B | ENCODES a protein that exhibits GTP binding; GTPase binding (ortholog); guanyl ribonucleotide binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to leucine starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); lysosome (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; aflatoxin B1 | X | 21560313 | 21610550 | Rat | 109 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309470 | Sesn3 | sestrin 3 | ENCODES a protein that exhibits oxidoreductase activity (inferred); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to glucose starvat ion (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); GATOR2 complex (ortholog); TORC2 complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 19415307 | 19470943 | Rat | 148 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308616 | Szt2 | SZT2 subunit of KICSTOR complex | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); central nervous system development (ortholog); ASSOCIATED WITH benign epilepsy with centrotemporal spikes (ortholog); cryptorchidism (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN GATOR1 complex (ortholog); GATOR2 complex (ortholog); KICSTOR complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 5 | 137182648 | 137229349 | Rat | 105 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309583 | Tfeb | transcription factor EB | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN antibacterial innate immune response (ortholog); cellular response to amino acid star 'font-weight:700;'>starvation (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 9 | 20696440 | 20752265 | Rat | 222 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311800 | Stbd1 | starch binding domain 1 | ENCODES a protein that exhibits cargo receptor activity (ortholog); enzyme binding (ortholog); glycogen binding (ortholog); INVOLVED IN glycogen catabolic process (ortholog); glycophagy (ortholog); lysosomal transport (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); perinu clear region of cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 15754769 | 15758174 | Rat | 182 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628638 | Rnf40 | ring finger protein 40 | ENCODES a protein that exhibits syntaxin-1 binding; ubiquitin conjugating enzyme binding; ubiquitin-protein transferase activity; INVOLVED IN positive regulation of proteasomal protein catabolic process; positive regulation of protein polyubiquitination; response to peptide hormone; PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH nephrogenic diabetes insipidus; FOUND IN protein-containing complex; HULC complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 1 | 191632988 | 191649231 | Rat | 114 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2773 | Gys2 | glycogen synthase 2 | ENCODES a protein that exhibits alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity; D-glucose binding; INVOLVED IN glycogen biosynthetic process; glycogen metabolic process; response to glucose; PARTICIPATES IN glycogen biosynthetic pathway; glycogen metabolic pathway; congenital sucr ase-isomaltase deficiency pathway; ASSOCIATED WITH genetic disease (ortholog); glycogen storage disease (ortholog); Glycogen Storage Disease 0, Liver (ortholog); FOUND IN cell cortex; cortical actin cytoskeleton; cytoplasm; INTERACTS WITH 1-benzylpiperazine; 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran | 4 | 177096063 | 177137236 | Rat | 184 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1589798 | Gys1 | glycogen synthase 1 | ENCODES a protein that exhibits alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity; D-glucose binding; glycogen synthase activity, transferring glucose-1-phosphate (ortholog); INVOLVED IN glycogen biosynthetic process; glycogen metabolic process; heart development (ortholog); PARTICIP ATES IN glycogen biosynthetic pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin signaling pathway; ASSOCIATED WITH cardiovascular system disease (ortholog); genetic disease (ortholog); Glycogen Storage Disease 0, Muscle (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); inclusion body (ortholog); INTERACTS WITH (+)-catechin; (3,4-dihydroxyphenyl)acetic acid; 17beta-estradiol | 1 | 105051916 | 105071763 | Rat | 181 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 401900752 | Prl7b1tm1(cre)Soar | prolactin family 7, subfamily B, member 1; CRISPR/Cas9 target mutant1, Soar | CRISPR/Cas9 system was used to introduce Cre recombinase downstream of the Prl7b1 start site. | | | | Rat | | description | gene, allele |
| 1598336 | Gys1-ps1 | glycogen synthase 1, pseudogene 1 | | 6 | 8667484 | 8669594 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 2022 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity; hydrolase activity; ferric iron binding (ortholog); INVOLVED IN bone resorption; cellular response to zinc ion starvation; multicellular organismal response to stress; PARTICIPATES IN rheumatoid arthriti s pathway; riboflavin metabolic pathway; ASSOCIATED WITH Alveolar Bone Loss; Experimental Diabetes Mellitus; Postmenopausal Osteoporosis; FOUND IN extracellular space; lysosome (ortholog); INTERACTS WITH (20S)-ginsenoside Rg3; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate | 8 | 28939984 | 28946639 | Rat | 297 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2015 | Acsl1 | acyl-CoA synthetase long-chain family member 1 | ENCODES a protein that exhibits arachidonate-CoA ligase activity; long-chain fatty acid-CoA ligase activity; oleoyl-CoA ligase activity; INVOLVED IN fatty acid metabolic process; fatty acid transport; long-chain fatty acid import into cell; PARTICIPATES IN adrenoleukodystrophy pathway; carnitine pal mitoyltransferase I deficiency pathway; carnitine-acylcarnitine translocase deficiency; ASSOCIATED WITH obesity; Starvation; Animal Mammary Neoplasms (ortholog); FOUND IN mitochondrial outer membrane; mitochondrion; peroxisomal membrane; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; 1-naphthyl isothiocyanate | 16 | 52487870 | 52554110 | Rat | 521 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620836 | Adgrl3 | adhesion G protein-coupled receptor L3 | ENCODES a protein that exhibits calcium ion binding (ortholog); cell adhesion mediator activity (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cell-cell adhesion (ortholog); excitatory syna pse assembly (ortholog); ASSOCIATED WITH enhanced behavioral response to amphetamine; hyperactivity; increased startle reflex; ASSOCIATED WITH Reperfusion Injury; attention deficit hyperactivity disorder (ortholog); FOUND IN axon (ortholog); cell-cell junction (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 14 | 26690891 | 27458132 | Rat | 178 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 127285662 | Adgrl3em1Huyc | adhesion G protein-coupled receptor L3; CRISPR/Cas9 induced mutant1, Huyc | ASSOCIATED WITH enhanced behavioral response to amphetamine; hyperactivity; increased startle reflex | | | | Rat | 4 | description | gene, allele |
| 621330 | Ambra1 | autophagy and beclin 1 regulator 1 | ENCODES a protein that exhibits GTPase binding (ortholog); protein phosphatase activator activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN cellular response to starvation; negative regulation of cardiac muscle cell apoptotic process; posit ive regulation of autophagy; PARTICIPATES IN inositol metabolic pathway; mitochondrial autophagy pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); esophageal atresia (ortholog); multiple system atrophy (ortholog); FOUND IN axoneme (ortholog); Cul4-RING E3 ubiquitin ligase complex (ortholog); cytoplasm (ortholog); INTERACTS WITH ammonium chloride; atrazine; Bardoxolone methyl | 3 | 98156626 | 98345876 | Rat | 166 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2113 | Amy1 | amylase alpha 1 | ENCODES a protein that exhibits alpha-amylase activity (inferred); amylase activity (inferred); catalytic activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); PARTICIPATES IN starch and sucrose metabolic pathway; FOUND IN extracellular spa ce; INTERACTS WITH bisphenol A; clofibric acid; lead diacetate | 2 | 204071101 | 204085910 | Rat | 45 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1593187 | Amy2a3 | amylase 2a3 | ENCODES a protein that exhibits alpha-amylase activity; calcium ion binding (ortholog); chloride ion binding (ortholog); INVOLVED IN carbohydrate catabolic process (ortholog); PARTICIPATES IN starch and sucrose metabolic pathway; FOUND IN extracellular space (or tholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 2 | 204005840 | 204014412 | Rat | 81 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2162 | Asns | asparagine synthetase (glutamine-hydrolyzing) | ENCODES a protein that exhibits asparagine synthase (glutamine-hydrolyzing) activity; identical protein binding; INVOLVED IN cellular response to glucose starvation; cellular response to hormone stimulus; liver development; PARTICIPATES IN Canavan disease pathwa y; alanine, aspartate and glutamate metabolic pathway; ASSOCIATED WITH hepatocellular carcinoma; retinal degeneration; RETINAL DYSTROPHY WITH INNER RETINAL DYSFUNCTION AND GANGLION CELL ABNORMALITIES; FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate | 4 | 36752061 | 36769970 | Rat | 463 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2165 | Atf3 | activating transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding (ortholog); INVOLVED IN positive regulation of cell population proliferation; positive regulation of transcript ion by RNA polymerase II; cellular response to amino acid starvation (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Myocardial Reperfusion Injury; Cardiomegaly (ortholog); cardiomyopathy (ortholog); FOUND IN CHOP-ATF3 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (S)-amphetamine; 1,2,4-trimethylbenzene; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine | 13 | 105274103 | 105331653 | Rat | 801 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621567 | Atxn3 | ataxin 3 | ENCODES a protein that exhibits histone deacetylase activity; histone deacetylase binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; INVOLVED IN protein modification process; actin cytoskeleton organization (ortholog); cellular response to amino acid star e='font-weight:700;'>starvation (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH atrophic muscular disease (ortholog); Cataplexy (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-diaminodiphenylmethane; acetamide | 6 | 126837107 | 126872919 | Rat | 231 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13782148 | Bace1em1Sage | | ASSOCIATED WITH abnormal motor coordination/balance; decreased locomotor activity; decreased myelin sheath thickness | | | | Rat | 7 | description | gene, allele |
| 620799 | Bnip1 | BCL2 interacting protein 1 | ENCODES a protein that exhibits calcium-induced calcium release activity (ortholog); SNAP receptor activity (ortholog); INVOLVED IN response to activity; response to oxygen-glucose deprivation; response to starvation; PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH Down syndrome (ortholog); spondyloepiphyseal dysplasia congenita (ortholog); Spondylopeiphyseal dysplasia, Holling type (ortholog); FOUND IN COPI-coated vesicle; SNARE complex; cytoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether | 10 | 16891317 | 16903561 | Rat | 130 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559440 | Cadps2 | calcium dependent secretion activator 2 | ENCODES a protein that exhibits lipid binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); positive regulation of exocytosis (ortholog); ASSOCIATED WITH autism s pectrum disorder (ortholog); autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cilium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3H-1,2-dithiole-3-thione | 4 | 52746054 | 53275252 | Rat | 164 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304774 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (ortholog); identical protein binding (ortholog); molecular sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to L-arginine (ortholog); negative regul ation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 14 | 83309710 | 83314123 | Rat | 90 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305773 | Clec16a | C-type lectin domain containing 16A | INVOLVED IN cellular response to starvation (ortholog); mitophagy (ortholog); negative regulation of autophagosome maturation (ortholog); ASSOCIATED WITH Addison's disease (ortholog); immunoglobulin alpha deficiency (ortholog); Meniere's disease (ortholog); FOUN D IN cytosol (ortholog); endolysosome membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; DDT | 10 | 5434725 | 5631246 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307076 | Cntnap2 | contactin associated protein 2 | ENCODES a protein that exhibits protease binding; transmembrane transporter binding; enzyme binding (ortholog); INVOLVED IN prepulse inhibition; startle response; action potential initiation (ortholog); ASSOCIATED WITH abnormal auditory brainstem response; abnor mal habituation; abnormal prepulse inhibition; ASSOCIATED WITH autism spectrum disorder; epilepsy; articulation disorder (ortholog); FOUND IN axolemma; dendrite; GABA-ergic synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 4 | 75109358 | 77366258 | Rat | 301 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311931 | Cpeb4 | cytoplasmic polyadenylation element binding protein 4 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN cellular response to amino acid stimulus; cellular response to decreased oxygen levels; cellular response to glucose starvation; ASSOCIATED WITH liver cirrhosis (ortholog); portal hypertension ( ortholog); primary biliary cholangitis (ortholog); FOUND IN cytoplasm; dendrite; nucleus; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran | 10 | 16222271 | 16284248 | Rat | 164 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2448 | Ctsl | cathepsin L | ENCODES a protein that exhibits aminopeptidase activity; cysteine-type endopeptidase activity; kininogen binding; INVOLVED IN autophagic cell death; cellular response to starvation; decidualization; PARTICIPATES IN chaperone mediated autophagy pathway; antigen p rocessing and presentation pathway; phagocytosis pathway; ASSOCIATED WITH Albuminuria; brain ischemia; Contusions; FOUND IN apical part of cell; external side of plasma membrane; microvillus; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 17 | 770104 | 776266 | Rat | 431 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311535 | Depdc5 | DEP domain containing 5, GATOR1 subcomplex subunit | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling p athway; ASSOCIATED WITH abnormal afterhyperpolarization; abnormal lateral ventricle morphology; abnormal neocortex morphology; ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Developmental and Epileptic Encephalopathy 111 (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); cytosol (ortholog); GATOR1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 14 | 81956777 | 82087392 | Rat | 117 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 38599194 | Depdc5em1Kyo | DEP domain containing 5, GATOR1 subcomplex subunit; TALEN induced mutant1, Kyo | ASSOCIATED WITH abnormal afterhyperpolarization; abnormal lateral ventricle morphology; abnormal neocortex morphology | | | | Rat | 5 | description | gene, allele |
| 38599195 | Depdc5em2Kyo | DEP domain containing 5, GATOR1 subcomplex subunit; TALEN induced mutant2, Kyo | ASSOCIATED WITH abnormal afterhyperpolarization; abnormal lateral ventricle morphology; abnormal neocortex morphology | | | | Rat | 5 | description | gene, allele |
| 2506 | Dlx5 | distal-less homeobox 5 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); HMG box domain binding (ortholog); INVOLVED IN cellular response to zinc ion starvation; positive regulation of osteoblas t differentiation; anatomical structure formation involved in morphogenesis (ortholog); ASSOCIATED WITH Birth Weight (ortholog); bone development disease (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil | 4 | 35965579 | 35969973 | Rat | 182 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307154 | Dnajc15 | DnaJ heat shock protein family (Hsp40) member C15 | INVOLVED IN cellular response to starvation (ortholog); negative regulation of mitochondrial electron transport, NADH to ubiquinone (ortholog); negative regulation of protein-containing complex assembly (ortholog); ASSOCIATED WITH melanoma (ortholog); FOUND IN m itochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; finasteride | 15 | 59594314 | 59658862 | Rat | 94 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309426 | Dsc2 | desmocollin 2 | ENCODES a protein that exhibits calcium ion binding (inferred); protein tyrosine kinase binding (inferred); INVOLVED IN bundle of His cell-Purkinje myocyte adhesion involved in cell communication (ortholog); cardiac muscle cell-cardiac muscle cell adhesion (ortholog); cellular response to star e='font-weight:700;'>starvation (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; ASSOCIATED WITH acute myocardial infarction; Cardiomegaly; dilated cardiomyopathy; FOUND IN adherens junction (ortholog); cytoplasmic vesicle (ortholog); desmosome (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 18 | 11725466 | 11757591 | Rat | 256 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1589591 | Eif2a | eukaryotic translation initiation factor 2A | ENCODES a protein that exhibits ribosome binding (ortholog); translation initiation factor activity (ortholog); tRNA binding (ortholog); INVOLVED IN response to amino acid starvation; positive regulation of signal transduction (ortholog); protein phosphorylation (ortholog); PARTICIPATES IN ceramide signaling pathway; endoplasmic reticulum stress - the unfolded protein response pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH borna disease; dystonia 33 (ortholog); Marinesco-Sjogren syndrome (ortholog); FOUND IN cytoplasm (ortholog); eukaryotic translation initiation factor 2 complex (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1,4-dithiothreitol; 17beta-estradiol | 2 | 144911247 | 144944705 | Rat | 280 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311439 | Eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | ENCODES a protein that exhibits eukaryotic translation initiation factor 2alpha kinase activity (ortholog); protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN positive regulation of protein phosphorylation; cellular response to amino acid star ='font-weight:700;'>starvation (ortholog); cellular response to cold (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; hepatitis C pathway; influenza A pathway; ASSOCIATED WITH pulmonary venoocclusive disease; amino acid metabolic disorder (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; amphetamine | 3 | 125810207 | 125895574 | Rat | 198 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620819 | Eif2b1 | eukaryotic translation initiation factor 2B subunit alpha | ENCODES a protein that exhibits GDP binding; GTP binding; guanyl-nucleotide exchange factor activity; INVOLVED IN negative regulation of guanyl-nucleotide exchange factor activity; response to amino acid starvation; response to glucose; PARTICIPATES IN translati on initiation pathway; RNA transport pathway; ASSOCIATED WITH Animal Disease Models (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN eukaryotic translation initiation factor 2 complex; eukaryotic translation initiation factor 2B complex; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride | 12 | 37686149 | 37694830 | Rat | 140 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310209 | Elapor1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | INVOLVED IN autophagosome assembly (ortholog); cellular response to starvation (ortholog); positive regulation of autophagosome assembly (ortholog); FOUND IN late endosome (ortholog); lysosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl iso thiocyanate; 4,4'-diaminodiphenylmethane; bisphenol A | 2 | 198777323 | 198856497 | Rat | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310977 | Epm2aip1 | EPM2A interacting protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic process (ortholog); response to insulin (ortholog); ASSOCIATED W ITH hereditary nonpolyposis colorectal cancer type 2 (ortholog); Lynch syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of endoplasmic reticulum membrane (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 120112265 | 120119613 | Rat | 122 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306664 | Fbxo22 | F-box protein 22 | INVOLVED IN cellular response to starvation (ortholog); nucleocytoplasmic transport (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Tayoun-Maawali syndrome (ortholog); FOUND IN cytoplasm (o rtholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; amphetamine | 8 | 64476034 | 64492063 | Rat | 99 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 124715480 | Fmr1em1Mzhe | FMRP translational regulator 1; CRISPR/Cas9 induced mutant1, Mzhe | ASSOCIATED WITH abnormal response to social novelty; abnormal temporal memory; enlarged testis; ASSOCIATED WITH fragile X syndrome | | | | Rat | 5 | description | gene, allele |
| 2318339 | Fnip1 | folliculin interacting protein 1 | ENCODES a protein that exhibits ATPase inhibitor activity (ortholog); enzyme activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN B cell differentiation (ortholog); cellular response to starvation (ortholog); immature B cell differentiation (ort holog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 93 (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17beta-estradiol; acetamide; amitrole | 10 | 39068432 | 39151552 | Rat | 138 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565754 | Fxn | frataxin | ENCODES a protein that exhibits enzyme binding; 2 iron, 2 sulfur cluster binding (ortholog); enzyme activator activity (ortholog); INVOLVED IN cellular response to glucose starvation; cellular response to hypoxia; iron import into the mitochondrion; PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH increased mitochondrial size; ASSOCIATED WITH Charcot-Marie-Tooth disease X-linked dominant 1 (ortholog); diabetes mellitus (ortholog); Friedreich ataxia (ortholog); FOUND IN mitochondrion; cytosol (ortholog); mitochondrial [2Fe-2S] assembly complex (ortholog); INTERACTS WITH (R)-lipoic acid; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 1 | 231300457 | 231323989 | Rat | 227 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 735227 | Gaa | alpha glucosidase | ENCODES a protein that exhibits alpha-1,4-glucosidase activity; carbohydrate binding; alpha-glucosidase activity (ortholog); INVOLVED IN glycogen catabolic process; aorta development (ortholog); diaphragm contraction (ortholog); PARTICIPATES IN galactose metabolic pathway; galactosemia pathway; ... (more) n style='font-weight:700;'>starch and sucrose metabolic pathway; ASSOCIATED WITH Cardiac Form of Generalized Glycogenosis (ortholog); cardiomyopathy (ortholog); COVID-19 (ortholog); FOUND IN autolysosome lumen (ortholog); lysosome (ortholog); membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 105028106 | 105045365 | Rat | 221 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2660 | Ganc | glucosidase, alpha; neutral C | ENCODES a protein that exhibits alpha-1,4-glucosidase activity (ortholog); INVOLVED IN carbohydrate metabolic process (inferred); PARTICIPATES IN galactose metabolic pathway; starch and sucrose metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradio l; 6-propyl-2-thiouracil | 3 | 127807132 | 127858995 | Rat | 61 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1311206 | Gas2l1 | growth arrest-specific 2 like 1 | ENCODES a protein that exhibits cytoskeletal anchor activity (ortholog); microtubule binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); microtubule bundle formation (ortholog); negative regulation of microtubule depolymerization (ortholo g); ASSOCIATED WITH acute myeloid leukemia (ortholog); FOUND IN actin filament (ortholog); cytoplasm (ortholog); microtubule (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; acrylamide | 14 | 84169398 | 84175514 | Rat | 94 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309539 | Gba3 | glucosylceramidase beta 3 | ENCODES a protein that exhibits beta-galactosidase activity (ortholog); beta-glucosidase activity (ortholog); galactosylceramidase activity (ortholog); INVOLVED IN beta-glucoside catabolic process (ortholog); galactosylceramide catabolic process (ortholog); glucosylceramide catabolic process (orthol og); PARTICIPATES IN cyanoamino acid metabolic pathway; starch and sucrose metabolic pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); substance-related disorder (ortholog); FOUND IN catalytic complex (ortholog); cytosol (ortholog); INTERACTS WITH 3,4-methylenedioxymethamphetamine; 3-chloropropane-1,2-diol; allopurinol | 14 | 64787601 | 64934043 | Rat | 86 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2670 | Gck | glucokinase | ENCODES a protein that exhibits ADP binding; ATP binding; D-glucose binding; INVOLVED IN carbohydrate phosphorylation; cellular response to glucose starvation; cellular response to insulin stimulus; PARTICIPATES IN glycogen biosynthetic pathway; glycogen metabol ic pathway; glycolysis pathway; ASSOCIATED WITH decreased circulating glucose level; increased circulating free fatty acids level; increased circulating triglyceride level; ASSOCIATED WITH Experimental Diabetes Mellitus; Insulin Resistance; Liver Injury; FOUND IN actin filament; basal cortex; cell cortex; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 84999019 | 85041098 | Rat | 521 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593434 | Gcn1 | GCN1 activator of EIF2AK4 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); protein serine/threonine kinase activator activity (ortholog); stalled ribosome sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); GCN2-mediated si gnaling (ortholog); protein-RNA covalent cross-linking repair (ortholog); ASSOCIATED WITH fetal akinesia deformation sequence syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); cytosolic ribosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 12 | 46652273 | 46715119 | Rat | 98 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 150429816 | Gnalem1Hpng | G protein subunit alpha L; CRISPR/Cas9 induced mutant 1, Hpng | ASSOCIATED WITH abnormal motor coordination/balance; abnormal motor learning; decreased locomotor activity; ASSOCIATED WITH dystonia | | | | Rat | 8 | description | gene, allele |
| 626419678 | Gnalem2Hpng | G protein subunit alpha L; CRISPR/Cas9 induced mutant 2, Hpng | Gnal knockout allele was generated by CRISPR/Cas9 technology. Exon1 of rat Gnal splicing variant 2 was targeted, resulting in a deletion of 1 base pair that corresponds to position 44 downstream of the translation start point ATG of the Gnal splicing variant 2. | | | | Rat | | description | gene, allele |
| 626419680 | Gnalem3Hpng | G protein subunit alpha L; CRISPR/Cas9 induced mutant 3, Hpng | The allele was generated by CRISPR/Cas9 technology. A deletion of 135 base pairs, corresponding to position 44-178, downstream of the translation initiation start ATG of the Gnal splicing variant 2, results in a deletion mutation. | | | | Rat | | description | gene, allele |
| 620179 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits catalytic activity (ortholog); glycerone-phosphate O-acyltransferase activity (ortholog); INVOLVED IN response to fatty acid; response to nutrient; response to starvation; PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalo gen metabolic pathway; glycerophospholipid metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane; peroxisome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol | 19 | 69719707 | 69746244 | Rat | 123 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309162 | Gpr155 | G protein-coupled receptor 155 | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to cholesterol (ortholog); cognition (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Hepatomegaly (orth olog); FOUND IN lysosomal membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol | 3 | 78623931 | 78677803 | Rat | 129 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305462 | Gpt2 | glutamic--pyruvic transaminase 2 | ENCODES a protein that exhibits L-alanine:2-oxoglutarate aminotransferase activity (ortholog); INVOLVED IN cellular response to insulin stimulus; gluconeogenesis; response to starvation; PARTICIPATES IN alanine, aspartate and glutamate metabolic pathway; ASSOCIA TED WITH Chemical and Drug Induced Liver Injury; type 2 diabetes mellitus; Chronic Hepatitis C (ortholog); FOUND IN extracellular space; mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 37700023 | 37734551 | Rat | 189 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2793 | Hfe | homeostatic iron regulator | ENCODES a protein that exhibits beta-2-microglobulin binding (ortholog); co-receptor binding (ortholog); peptide antigen binding (ortholog); INVOLVED IN acute-phase response; cellular response to iron ion starvation; female pregnancy; ASSOCIATED WITH alcohol-ass ociated liver disease; Abdominal Pain (ortholog); Alzheimer's disease (ortholog); FOUND IN apical part of cell; terminal web; basal part of cell (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride | 17 | 41841302 | 41849359 | Rat | 293 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620215 | Higd1a | HIG1 hypoxia inducible domain family, member 1A | INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); negative regulation of apoptotic process (ortholog); FOUND IN membrane (ortholog); mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERAC TS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 130391658 | 130400888 | Rat | 132 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 71059 | Hnrnpl | heterogeneous nuclear ribonucleoprotein L | ENCODES a protein that exhibits mRNA 3'-UTR binding; mRNA CDS binding; pre-mRNA intronic binding (ortholog); INVOLVED IN cellular response to amino acid starvation; circadian rhythm; negative regulation of mRNA splicing, via spliceosome; PARTICIPATES IN spliceos ome pathway; ASSOCIATED WITH brain cancer (ortholog); Breast Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN perinuclear region of cytoplasm; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 1 | 93226373 | 93239084 | Rat | 162 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 70549 | Hrk | harakiri, BCL2 interacting protein | INVOLVED IN cellular response to potassium ion starvation; positive regulation of neuron apoptotic process; positive regulation of apoptotic process (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog) ; FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-pilocarpine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 44048402 | 44070561 | Rat | 167 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1591977 | Impact | impact RWD domain protein | ENCODES a protein that exhibits actin binding (ortholog); protein sequestering activity (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); GCN2-mediated signaling (ortholog); intracellular signal transduct ion (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil | 18 | 4383546 | 4422280 | Rat | 137 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2917 | Insr | insulin receptor | ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; cargo receptor activity; insulin binding; INVOLVED IN amyloid-beta clearance; cellular response to zinc ion starvation; cerebellum development; PARTICIPATES IN altered leptin sy stem pathway; insulin signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH decreased body weight; increased circulating glucose level; increased circulating insulin level; ASSOCIATED WITH Alzheimer's disease; chronic kidney disease; diabetic neuropathy; FOUND IN cell body; dendrite; dendrite membrane; INTERACTS WITH (+)-catechin; (3,4-dihydroxyphenyl)acetic acid; (S)-nicotine | 12 | 5991135 | 6129275 | Rat | 653 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 329845587 | Izumo1em1Osb | izumo sperm-oocyte fusion 1;CRISPR/Cas9 induced mutant 1,Osb | This CRISPR/Cas9 induced mutant allele carries a 7-bp deletion(CTTTGGA)after start codon (Met) in exon2 of Izumo1 gene. | | | | Rat | | description | gene, allele |
| 2943 | Jun | Jun proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; double-stranded DNA binding; INVOLVED IN angiogenesis; cellular response to hypoxia; cellular response to potassium ion star starvation; PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; adenosine signaling pathway; endothelin signaling pathway; ASSOCIATED WITH Alcohol-Related Disorders; depressive disorder; hypertension; FOUND IN chromatin; nucleus; protein-containing complex; INTERACTS WITH (+)-pilocarpine; (-)-anisomycin; (R)-lipoic acid | 5 | 115009900 | 115012993 | Rat | 1798 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620396 | Kl | Klotho | ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); fibroblast growth factor receptor binding (ortholog); INVOLVED IN negative regulation of systemic arterial blood pressure; norepinephrine biosynthetic process; response to activity; PARTICIPATES IN fibroblast growth factor signaling pathway; pentose and glucuronate interconversion pathway; starch and sucrose metabolic pathway; ASSOCIATED WITH chronic kidney disease; Diabetic Nephropathies; end stage renal disease; FOUND IN apical plasma membrane (inferred); extracellular region (inferred); plasma membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-methyladenine | 12 | 5326003 | 5367016 | Rat | 243 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628646 | Krt20 | keratin 20 | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN cellular response to starvation (ortholog); intermediate filament organization (ortholog); regulation of protein secretion (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Cecal Neoplasms (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamide | 10 | 84880952 | 84890285 | Rat | 120 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304962 | Lars1 | leucyl-tRNA synthetase 1 | ENCODES a protein that exhibits aminoacyl-tRNA deacylase activity (ortholog); glutamine-tRNA ligase activity (ortholog); GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stim ulus (ortholog); cellular response to L-leucine (ortholog); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; valine, leucine and isoleucine biosynthetic pathway; ASSOCIATED WITH infantile liver failure syndrome 1 (ortholog); microcephaly (ortholog); sensorineural hearing loss (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 18 | 34452567 | 34507030 | Rat | 161 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 402075879 | LOC134486345 | serine/threonine-protein kinase 24-like | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to oxidative stress (inferred); cellular response to starvation (inferred); execution phase of apoptosis (inferred); F OUND IN cytoplasm (inferred); cytosol (inferred); FAR/SIN/STRIPAK complex (inferred) | 3 | 18234608 | 18236670 | Rat | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 735183 | Map1lc3a | microtubule-associated protein 1 light chain 3 alpha | ENCODES a protein that exhibits phospholipid binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN autophagosome assembly; autophagy; cellular response to amino acid starvation; PARTICIPATES IN autophagy pathway; ASSOCIATED WITH acute myoc ardial infarction; Brain Hypoxia-Ischemia; Brain Injuries; FOUND IN autophagosome; autophagosome membrane; cytoplasm; INTERACTS WITH 1,3-dichloropropan-2-ol; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 3 | 164243204 | 164244850 | Rat | 365 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621101 | Max | MYC associated transcriptional regulator X | ENCODES a protein that exhibits DNA-binding transcription factor activity; identical protein binding; protein-containing complex binding; INVOLVED IN cellular response to peptide hormone stimulus; cellular response to starvation; negative regulation of gene expr ession; PARTICIPATES IN mitogen activated protein kinase signaling pathway; small cell lung carcinoma pathway; ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); Hereditary Paraganglioma-Pheochromocytoma Syndromes (ortholog); lung small cell carcinoma (ortholog); FOUND IN dendrite; nucleus; PML body; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 101369989 | 101395333 | Rat | 158 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307394 | Mfsd11 | major facilitator superfamily domain containing 11 | INVOLVED IN response to food (ortholog); response to starvation (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 10 | 102554409 | 102573866 | Rat | 53 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310174 | Mfsd2a | MFSD2 lysolipid transporter A, lysophospholipid | ENCODES a protein that exhibits fatty acid transmembrane transporter activity (ortholog); long-chain fatty acid transmembrane transporter activity (ortholog); lysophosphatidylcholine flippase activity (ortholog); INVOLVED IN brain development (ortholog); cellular response to star :700;'>starvation (ortholog); cognition (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN lysosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 140510933 | 140525828 | Rat | 279 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308432 | Mios | meiosis regulator for oocyte development | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); central nervous system myelin formation (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog) ; lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 4 | 37229533 | 37255862 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3092 | Mitf | melanocyte inducing transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to zinc ion starvation; DNA-templated transcription; osteocla st differentiation; PARTICIPATES IN interleukin-6 signaling pathway; melanoma pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness (ortholog); Camurati-Engelmann disease (ortholog); COLOBOMA, OSTEOPETROSIS, MICROPHTHALMIA, MACROCEPHALY, ALBINISM, AND DEAFNESS (ortholog); FOUND IN cytoplasm (ortholog); lysosomal membrane (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 131965676 | 132177790 | Rat | 328 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310972 | Mtmr3 | myotubularin related protein 3 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity (ortholog); phosphatidylinositol-3-phosphate phosphatase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); midbody abscission (ortholog); phosphatidylinositol 5-phosphate metabolic process (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 14 | 83564065 | 83684573 | Rat | 126 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 62062 | Mybbp1a | MYB binding protein 1a | ENCODES a protein that exhibits sequence-specific DNA binding; E-box binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); circadian regulation of gene expression (ortholog); intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Meniere's disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); NLS-dependent protein nuclear import complex (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene | 10 | 57555458 | 57565819 | Rat | 193 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3137 | Myh13 | myosin heavy chain 13 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN cellular response to starvation (ortholog); PARTICIPATES IN myocarditis pathway; ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN myofibril (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; Cuprizon | 10 | 52511773 | 52567951 | Rat | 45 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308927 | Nprl2 | NPR2-like, GATOR1 complex subunit | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR si gnaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variable foci 1 (ortholog); FOUND IN GATOR1 complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 8 | 117094443 | 117097639 | Rat | 78 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308665 | Nprl3 | NPR3-like, GATOR1 complex subunit | INVOLVED IN aorta morphogenesis (ortholog); cardiac muscle tissue development (ortholog); cellular response to amino acid starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable fo ci 1 (ortholog); familial focal epilepsy with variable foci 3 (ortholog); FOUND IN GATOR1 complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 10 | 15859739 | 15900261 | Rat | 88 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 61909 | Nr1h3 | nuclear receptor subfamily 1, group H, member 3 | ENCODES a protein that exhibits nuclear retinoid X receptor binding; protein-containing complex binding; sequence-specific DNA binding; INVOLVED IN cellular response to starvation; digestive tract development; insulin receptor signaling pathway; PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; hepatitis C pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; metabolic dysfunction and alcohol associated liver disease; Metabolic Syndrome; FOUND IN nucleolus; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; (25R)-cholest-5-ene-3beta,26-diol; (S)-nicotine | 3 | 97614616 | 97632053 | Rat | 571 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359167 | Nuak2 | NUAK family kinase 2 | ENCODES a protein that exhibits ATP binding; magnesium ion binding; protein serine/threonine kinase activity; INVOLVED IN cellular response to glucose starvation; protein phosphorylation; actin cytoskeleton organization (ortholog); ASSOCIATED WITH Anencephaly 2 (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene | 13 | 46305744 | 46322755 | Rat | 159 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560258 | Nupr2 | nuclear protein 2, transcriptional regulator | INVOLVED IN cellular response to starvation (ortholog); DNA damage response (ortholog); negative regulation of cell population proliferation (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; 3-chloropropa ne-1,2-diol | 12 | 32436233 | 32439391 | Rat | 48 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 728909 | Pcsk9 | proprotein convertase subtilisin/kexin type 9 | ENCODES a protein that exhibits apolipoprotein binding (ortholog); apolipoprotein receptor binding (ortholog); endopeptidase activity (ortholog); INVOLVED IN cellular response to insulin stimulus; cellular response to starvation; cholesterol homeostasis; ASSOCIA TED WITH autosomal recessive hypercholesterolemia (ortholog); coronary artery disease (ortholog); Coronary Disease (ortholog); FOUND IN extracellular space; cell surface (ortholog); COPII-coated ER to Golgi transport vesicle (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine | 5 | 126440102 | 126462507 | Rat | 388 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 69061 | Pdk4 | pyruvate dehydrogenase kinase 4 | ENCODES a protein that exhibits ATP binding; pyruvate dehydrogenase (acetyl-transferring) kinase activity; protein kinase activity (ortholog); INVOLVED IN protein phosphorylation; cellular response to fatty acid (ortholog); cellular response to starvation (ortho log); PARTICIPATES IN pyruvate metabolic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Diabetes Mellitus (ortholog); hepatocellular carcinoma (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 34558327 | 34568329 | Rat | 499 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628812 | Pdp2 | pyruvate dehydrogenase phosphatase catalytic subunit 2 | ENCODES a protein that exhibits [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity; protein serine/threonine phosphatase activity; INVOLVED IN peptidyl-threonine dephosphorylation; response to starvation; T-helper cell differentiation (ortholog) ; PARTICIPATES IN pyruvate metabolic pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; prostate cancer (ortholog); FOUND IN mitochondrion; INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 17alpha-ethynylestradiol | 19 | 392858 | 400529 | Rat | 128 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69437 | Pick1 | protein interacting with PRKCA 1 | ENCODES a protein that exhibits actin filament binding; Arp2/3 complex binding; cytoskeletal protein binding; INVOLVED IN AMPA glutamate receptor clustering; cellular response to decreased oxygen levels; cellular response to glucose starvation; PARTICIPATES IN p rotein kinase C (PKC) signaling pathway; ASSOCIATED WITH amphetamine abuse (ortholog); substance-induced psychosis (ortholog); FOUND IN dendrite; dendritic spine; dendritic spine cytoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 112676890 | 112697275 | Rat | 218 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310389 | Pik3c2a | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog); 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (ortholog); 1-phosphatidylinositol-4-phosphate 3-kinase activity (ortholog); INVOLVED IN autophagosome organization (ortholog); cellular response to star yle='font-weight:700;'>starvation (ortholog); endocytosis (ortholog); PARTICIPATES IN phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH Dwarfism (ortholog); Oculoskeletodental Syndrome (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN clathrin-coated vesicle (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; DDT | 1 | 180012248 | 180117786 | Rat | 182 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306541 | Pik3c2b | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog); 1-phosphatidylinositol-4-phosphate 3-kinase activity (ortholog); lipid kinase activity (ortholog); INVOLVED IN autophagosome organization (ortholog); cellular response to starva tion (ortholog); macroautophagy (ortholog); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH Neoplasm Metastasis (ortholog); FOUND IN cytosol (ortholog); endocytic vesicle (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 13 | 47046866 | 47107733 | Rat | 129 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311809 | Pik3r4 | phosphoinositide-3-kinase, regulatory subunit 4 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN autophagosome maturation (ortholog); cellular response to glucose starvation (ortholog); early endosome to late endosome transport (ort holog); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; phosphoinositide metabolic pathway; FOUND IN axoneme (ortholog); late endosome (ortholog); phosphatidylinositol 3-kinase complex, class III (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; atrazine | 8 | 115146660 | 115195326 | Rat | 117 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 5143976 | Plcd3em7Mcwi | phospholipase C, delta 3; zinc finger nuclease induced mutant 7, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting mutation is a 142-bp deletion, overlapping the start codon (del 68-209) | | | | Rat | | description | gene, allele |
| 728889 | Plin2 | perilipin 2 | INVOLVED IN response to xenobiotic stimulus; cellular response to glucose starvation (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Hypertriglyceridemia (ortholog); Insulin Resistance (ortholog); FOUND IN lipid droplet; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate | 5 | 106202634 | 106258748 | Rat | 392 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595854 | Plin3 | perilipin 3 | INVOLVED IN cellular response to glucose starvation (ortholog); lipid droplet disassembly (ortholog); lipid storage (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN lipid droplet (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 1198336 | 1210212 | Rat | 135 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359266 | Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | INVOLVED IN positive regulation of apoptotic process; apoptotic process (ortholog); cellular response to glucose starvation (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; p53 signaling pathway; ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortho log); COVID-19 (ortholog); substance-related disorder (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 62255970 | 62262384 | Rat | 452 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305460 | Ppm1d | protein phosphatase, Mg2+/Mn2+ dependent, 1D | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN cellular response to starvation; DNA damage response, signal transduction by p53 class mediator (ortholog); DNA methylation-dependent constitutive heterochromatin formation (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; p38 MAPK signaling pathway; p53 signaling pathway; ASSOCIATED WITH Brain Stem Neoplasms (ortholog); breast cancer (ortholog); Breast Cancer, Familial (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Ampullosporin; bisphenol A | 10 | 70670026 | 70706030 | Rat | 214 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621526 | Ppp1r15a | protein phosphatase 1, regulatory subunit 15A | ENCODES a protein that exhibits protein phosphatase 1 binding; eukaryotic initiation factor eIF2 binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to antibiotic; cellular response to calcium ion starvation; cellular respons e to carbohydrate stimulus; PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH brain ischemia; Emphysema; Spinal Cord Injuries; FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 105136521 | 105139596 | Rat | 447 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566398 | Ppp1r3f | protein phosphatase 1, regulatory subunit 3F | ENCODES a protein that exhibits glycogen binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN regulation of glycogen (starch) synthase activity (ortholog); regulation of glycogen biosynthetic process (ortholog); FOUND IN membrane (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 3-isobutyl-1-methyl-7H-xanthine (ortholog); 4,4'-diaminodiphenylmethane (ortholog) | X | 17581467 | 17617087 | Rat | 42 | description | gene, protein-coding, INFERRED [RefSeq] |
| 1308930 | Ppp1r3g | protein phosphatase 1, regulatory subunit 3G | ENCODES a protein that exhibits glycogen binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN glucose homeostasis (ortholog); positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic p rocess (ortholog); FOUND IN cytoplasm (ortholog); protein phosphatase type 1 complex (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 17 | 29080407 | 29083739 | Rat | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 67383 | Prkcd | protein kinase C, delta | ENCODES a protein that exhibits diacylglycerol-dependent, calcium-independent serine/threonine kinase activity; protein kinase binding; protein serine/threonine kinase binding; INVOLVED IN apoptotic process; cellular response to glucose starvation; cellular resp onse to insulin stimulus; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; vascular endothelial growth factor signaling pathway; ceramide signaling pathway; ASSOCIATED WITH brain ischemia; Burns; Cardiomegaly; FOUND IN postsynaptic cytosol; cell-cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine | 16 | 5775681 | 5806122 | Rat | 638 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621888 | Prkch | protein kinase C, eta | ENCODES a protein that exhibits diacylglycerol-dependent, calcium-independent serine/threonine kinase activity; enzyme binding (ortholog); protein kinase activity (ortholog); INVOLVED IN phospholipase C/protein kinase C signal transduction; protein phosphorylation; cellular response to amino acid ... (more)pan style='font-weight:700;'>starvation (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; eicosanoid signaling pathway; endothelin signaling pathway; ASSOCIATED WITH cerebral infarction (ortholog); obesity (ortholog); substance-related disorder (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-pilocarpine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 98027830 | 98226486 | Rat | 219 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305891 | Pwwp2a | PWWP domain containing 2A | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone H3K36me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of transcription elongation by RNA polymerase II (ortholog); regulation of transcriptional star le='font-weight:700;'>start site selection at RNA polymerase II promoter (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 28654272 | 28696693 | Rat | 73 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3460 | Pygb | glycogen phosphorylase B | ENCODES a protein that exhibits carbohydrate binding; glycogen phosphorylase activity; identical protein binding; INVOLVED IN glycogen catabolic process; glycogen metabolic process; PARTICIPATES IN glycogen degradation pathway; insulin signaling pathway; starch and sucrose metabolic pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Dwarfism (ortholog); Myocardial Ischemia (ortholog); FOUND IN axon; cytoplasm (ortholog); INTERACTS WITH 2,5-hexanedione; 3-chloropropane-1,2-diol; acetamide | 3 | 160072141 | 160118930 | Rat | 180 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3461 | Pygm | glycogen phosphorylase, muscle associated | ENCODES a protein that exhibits AMP binding; carbohydrate binding; glycogen phosphorylase activity; INVOLVED IN glycogen catabolic process; glycogen metabolic process; intracellular calcium ion homeostasis; PARTICIPATES IN glycogen degradation pathway; insulin signaling pathway; star ight:700;'>starch and sucrose metabolic pathway; ASSOCIATED WITH cholestasis; Experimental Diabetes Mellitus; Myocardial Ischemia; FOUND IN sarcoplasmic reticulum; INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 213119805 | 213134622 | Rat | 198 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307772 | Ripor1 | RHO family interacting cell polarization regulator 1 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); INVOLVED IN cellular response to chemokine (ortholog); cellular response to starvation (ortholog); establishment of Golgi localization (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 19 | 50387447 | 50416323 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 61823 | Rnase4 | ribonuclease A family member 4 | ENCODES a protein that exhibits RNA nuclease activity (ortholog); INVOLVED IN antibacterial humoral response (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 15 | 26786287 | 26803634 | Rat | 207 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305251 | Rnf152 | ring finger protein 152 | ENCODES a protein that exhibits small GTPase binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of TORC1 sign aling (ortholog); positive regulation of autophagy (ortholog); FOUND IN lysosomal membrane (ortholog); lysosome (ortholog); organelle membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 13 | 21838634 | 21918000 | Rat | 135 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305972 | Rnf167 | ring finger protein 167 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); lysosome localization (ortholog); negative regulation of cell cycle ( ortholog); ASSOCIATED WITH systemic primary carnitine deficiency disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endolysosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 55859254 | 55863546 | Rat | 130 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310607 | Rpl26 | ribosomal protein L26 | ENCODES a protein that exhibits mRNA 5'-UTR binding (ortholog); structural constituent of ribosome (ortholog); INVOLVED IN response to amino acid starvation; cellular response to gamma radiation (ortholog); cellular response to ionizing radiation (ortholog); PAR TICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH congenital hypoplastic anemia (ortholog); Diamond-Blackfan anemia (ortholog); Diamond-Blackfan anemia 11 (ortholog); FOUND IN cytosolic large ribosomal subunit; terminal bouton; cytoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 54109692 | 54112822 | Rat | 149 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621043 | Rps25 | ribosomal protein s25 | ENCODES a protein that exhibits structural constituent of ribosome; INVOLVED IN cellular response to amino acid starvation; ribosomal small subunit assembly; ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; FOUND IN cytosolic small ribosomal subunit; cytosol (ortholog); cytosolic ribosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene | 8 | 53630333 | 53632810 | Rat | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619804 | Rraga | Ras-related GTP binding A | ENCODES a protein that exhibits GTP binding; GTPase activity (ortholog); phosphoprotein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to nutrient leve ls (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); GATOR1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione | 5 | 106159335 | 106160930 | Rat | 172 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311760 | Rragc | Ras-related GTP binding C | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); GDP binding (ortholog); GTP binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH follicular lymphoma (ortholog); genetic disease (ortholog); LONG-OLSEN-DISTELMAIER SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 141433014 | 141452546 | Rat | 136 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310007 | Rragd | Ras-related GTP binding D | ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN cellular response to L-leucine (ortholog); cellular response to leucine starvation (ortholog); positive regulation of TORC1 signaling (ortholo g); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); renal hypomagnesemia 7, with or without dilated cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); lysosome (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 17beta-estradiol | 5 | 52170234 | 52205700 | Rat | 180 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308302 | Rrp8 | ribosomal RNA processing 8 | ENCODES a protein that exhibits methyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN cellular response to glucose starvation (ortholog); energy homeostasis (ortholog); intrinsic apoptotic signaling pathway by p53 class mediator (or tholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN chromatin silencing complex (ortholog); cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 169489829 | 169500551 | Rat | 95 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1588441 | Samtor | S-adenosylmethionine sensor upstream of mTORC1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); S-adenosyl-L-methionine binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to methionine (ortholog); positive regulation of TORC1 signaling (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 4 | 42847720 | 42911546 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359540 | Sar1a | secretion associated, Ras related GTPase 1A | ENCODES a protein that exhibits amino acid sensor activity (ortholog); G protein activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); COPII vesicle coating (ortholog); COPII-coated vesicle cargo loading (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN COPII vesicle coat (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum exit site (ortholog); INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 30166310 | 30178718 | Rat | 140 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305590 | Sar1b | secretion associated, Ras related GTPase 1B | ENCODES a protein that exhibits amino acid sensor activity (ortholog); G protein activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); COPII vesicle coating (ortholog); COPII-coated vesicle cargo loading (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH chylomicron retention disease (ortholog); genetic disease (ortholog); Hereditary Pancreatitis (ortholog); FOUND IN COPII vesicle coat (ortholog); cytosol (ortholog); endoplasmic reticulum exit site (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 10 | 36525365 | 36555009 | Rat | 175 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 6490353 | Seh1l | SEH1-like nucleoporin | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); PAR TICIPATES IN mRNA nuclear export pathway; ASSOCIATED WITH tooth agenesis (ortholog); FOUND IN GATOR2 complex (ortholog); kinetochore (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; (+)-catechin (ortholog) | 18 | 63612228 | 63639852 | Rat | 102 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307517 | Sesn1 | sestrin 1 | ENCODES a protein that exhibits L-leucine binding (ortholog); INVOLVED IN cellular oxidant detoxification (ortholog); cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); PARTICIPATES IN p53 signaling pathwa y; FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); GATOR2 complex (ortholog); INTERACTS WITH (S)-colchicine; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 20 | 46876918 | 46970010 | Rat | 227 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566319 | Sesn2 | sestrin 2 | ENCODES a protein that exhibits GDP-dissociation inhibitor activity (ortholog); L-leucine binding (ortholog); peroxidase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cellular oxidant detoxification (ortholog); cellular response to amino acid star ight:700;'>starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); Hepatomegaly (ortholog); FOUND IN Atg1/ULK1 kinase complex (ortholog); cytoplasm (ortholog); GATOR2 complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 149986304 | 150005255 | Rat | 411 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 69420 | Slc38a2 | solute carrier family 38, member 2 | ENCODES a protein that exhibits acidic amino acid transmembrane transporter activity; alanine:sodium symporter activity; amino acid:sodium symporter activity; INVOLVED IN alanine transport; amino acid import; cellular response to amino acid starvation; PARTICIPA TES IN glutamate signaling pathway; ASSOCIATED WITH Contusions; Experimental Diabetes Mellitus; Experimental Seizures; FOUND IN axon; brush border; dendrite; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 129730450 | 129742619 | Rat | 308 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306701 | Slc39a4 | solute carrier family 39 member 4 | ENCODES a protein that exhibits identical protein binding (ortholog); metal ion binding (ortholog); zinc ion binding (ortholog); INVOLVED IN cellular response to zinc ion starvation (ortholog); intracellular zinc ion homeostasis (ortholog); zinc ion transmembran e transport (ortholog); ASSOCIATED WITH acrodermatitis (ortholog); acrodermatitis enteropathica (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); cytoplasmic vesicle (ortholog); endosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 7 | 110214017 | 110218202 | Rat | 215 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310322 | Slc39a5 | solute carrier family 39 member 5 | ENCODES a protein that exhibits zinc ion transmembrane transporter activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cellular response to zinc ion starvation (ortholog); eye development (ortholog); ASSOCIATED WITH Myopia 24, Autosomal Dominant ( ortholog); retinitis pigmentosa 1 (ortholog); FOUND IN basolateral plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 1409360 | 1415407 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3073 | Slc3a2 | solute carrier family 3 member 2 | ENCODES a protein that exhibits neutral L-amino acid transmembrane transporter activity; aromatic amino acid transmembrane transporter activity (ortholog); double-stranded RNA binding (ortholog); INVOLVED IN cellular response to glucose starvation; L-histidine t ransport; L-leucine import across plasma membrane; PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Liver Metastasis; transitional cell carcinoma; adenoid cystic carcinoma (ortholog); FOUND IN apical plasma membrane; basal plasma membrane; amino acid transport complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 1 | 215033601 | 215048064 | Rat | 491 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305138 | Slc61a1 | solute carrier family 61 member 1 | ENCODES a protein that exhibits molybdate ion transmembrane transporter activity (ortholog); INVOLVED IN molybdate ion transport (ortholog); response to food (ortholog); response to starvation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 7 | 135287683 | 135289964 | Rat | 59 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14390068 | Slc6a4m1Hubr | solute carrier family 6 member 4; ZFN induced mutant1, Hubr | ASSOCIATED WITH abnormal acquisiton of operant behavior for a cocaine reinforcer; abnormal cocaine self-administration; anhedonia; ASSOCIATED WITH anxiety disorder; depressive disorder | | | | Rat | 11 | description | gene, allele |
| 620639 | Slc7a5 | solute carrier family 7 member 5 | ENCODES a protein that exhibits amino acid transmembrane transporter activity; antiporter activity (ortholog); aromatic amino acid transmembrane transporter activity (ortholog); INVOLVED IN amino acid import across plasma membrane; cellular response to amino acid stimulus; cellular response to gluco se starvation; PARTICIPATES IN mTOR signaling pathway; amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; Endotoxemia; Experimental Liver Neoplasms; FOUND IN apical plasma membrane; basal plasma membrane; basolateral plasma membrane; INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene; 17alpha-ethynylestradiol; 17beta-estradiol | 19 | 66843808 | 66872412 | Rat | 494 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621391 | Slco2b1 | solute carrier organic anion transporter family, member 2b1 | ENCODES a protein that exhibits transmembrane transporter activity; prostaglandin transmembrane transporter activity (ortholog); secondary active transmembrane transporter activity (ortholog); INVOLVED IN liver development; cell population proliferation (ortholog); cellular response to iron ion ... (more) n style='font-weight:700;'>starvation (ortholog); PARTICIPATES IN statin pharmacokinetics pathway; ASSOCIATED WITH liver cancer (ortholog); pancreatic cancer (ortholog); FOUND IN apical plasma membrane; basal plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 163371410 | 163419412 | Rat | 288 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311310 | Smdt1 | single-pass membrane protein with aspartate-rich tail 1 | ENCODES a protein that exhibits channel activator activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN calcium import into the mitochondrion (ortholog); cellular response to calcium ion starvation (ortholog); mitochondrial calcium ion homeostasis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); uniplex complex (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole | 7 | 115742240 | 115745323 | Rat | 51 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 631377 | Sp7 | Sp7 transcription factor | ENCODES a protein that exhibits DEAD/H-box RNA helicase binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to parathyroid hormone stimulus; cellular response to zinc ion star ht:700;'>starvation; response to insulin; ASSOCIATED WITH aortic valve stenosis (ortholog); BCARD syndrome (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 5-formyltetrahydrofolic acid; ammonium chloride; arsenous acid | 7 | 135363193 | 135373376 | Rat | 221 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620048 | Sphk1 | sphingosine kinase 1 | ENCODES a protein that exhibits acetyltransferase activity (ortholog); ATP binding (ortholog); calmodulin binding (ortholog); INVOLVED IN cellular response to growth factor stimulus; cellular response to hydrogen peroxide; cellular response to starvation; PARTIC IPATES IN platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH adenocarcinoma; high grade glioma; Fibrosis (ortholog); FOUND IN axon; synaptic vesicle; clathrin-coated pit (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 102257413 | 102263086 | Rat | 394 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69423 | Srebf1 | sterol regulatory element binding transcription factor 1 | ENCODES a protein that exhibits chromatin binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein-containing complex binding; INVOLVED IN cellular response to fatty acid; cellular response to insulin stimulus; cellular response to star rvation; PARTICIPATES IN triacylglycerol metabolic pathway; mTOR signaling pathway; sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH abnormal triglyceride level; decreased cholesterol level; ASSOCIATED WITH alcoholic hepatitis; Diabetic Nephropathies; diabetic neuropathy; FOUND IN protein-containing complex; cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (+)-catechin; (-)-cotinine; (-)-epigallocatechin 3-gallate | 10 | 45507152 | 45529164 | Rat | 1099 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561742 | Stk24 | serine/threonine kinase 24 | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN positive regulation of axon regeneration; cellular response to oxidative stress (ortholog); cellular response to starvation (ortholog); FOUND IN Golgi membrane; cyto plasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; aflatoxin B1 | 15 | 104770556 | 104866524 | Rat | 155 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563568 | Stk26 | serine/threonine kinase 26 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); cellular response to starvation (ortholog); intracellular signal transdu ction (ortholog); FOUND IN Golgi membrane; apical plasma membrane (ortholog); cell periphery (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; alpha-Zearalanol | X | 135195176 | 135259994 | Rat | 123 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565692 | Suv39h1-ps1 | SUV39H1 histone lysine methyltransferase, pseudogene 1 | ENCODES a pseudogene that exhibits histone H3K14ub reader activity (ortholog); histone H3K9 methyltransferase activity (ortholog); histone H3K9 trimethyltransferase activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); cellular response to glucose star >vation (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH Chromosome Breakage (ortholog); Ependymomas (ortholog); Neoplastic Cell Transformation (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); heterochromatin (ortholog); INTERACTS WITH 17beta-estradiol; 1,1-dichloroethene (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | X | 146828818 | 146831485 | Rat | 161 | description | gene, pseudo, INFERRED [RefSeq] |
| 1307661 | Tbc1d7 | TBC1 domain family, member 7 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN activation of GTPase activity (ortholog); cellular response to starvation (ortholog); negative regulation of cilium assembly (ortholog); PARTICIPAT ES IN mTOR signaling pathway; FOUND IN ciliary basal body (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol | 17 | 21736898 | 21754499 | Rat | 59 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1595038 | Tbl2 | transducin (beta)-like 2 | ENCODES a protein that exhibits phosphoprotein binding (ortholog); protein kinase binding (ortholog); translation initiation factor binding (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); endop lasmic reticulum unfolded protein response (ortholog); ASSOCIATED WITH COVID-19 (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH bisphenol A; endosulfan; paracetamol | 12 | 27154150 | 27168446 | Rat | 75 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563614 | Tnfrsf11a | TNF receptor superfamily member 11A | ENCODES a protein that exhibits cytokine binding (ortholog); transmembrane signaling receptor activity (ortholog); tumor necrosis factor receptor activity (ortholog); INVOLVED IN cellular response to zinc ion starvation; osteoclast differentiation; response to e thanol; PARTICIPATES IN cytokine mediated signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH Alveolar Bone Loss; myocarditis; Tibial Fractures; FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); membrane raft (ortholog); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 13 | 22442930 | 22501257 | Rat | 222 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307268 | Tnrc6a | trinucleotide repeat containing adaptor 6A | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN cellular response to starvation (ortholog); endoderm development (ortholog); miRNA-mediated gene silencing by inhibition of translation (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH familial adult myoclonic epilepsy 6 (ortholog); Myoclonic Epilepsies (ortholog); FOUND IN P-body (ortholog); RISC complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 186992457 | 187146764 | Rat | 134 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 61831 | Treh | trehalase | ENCODES a protein that exhibits alpha,alpha-trehalase activity (ortholog); INVOLVED IN animal organ morphogenesis; trehalose catabolic process (ortholog); PARTICIPATES IN trehalose degradation pathway; starch and sucrose metabolic pathway; ASSOCIATED WITH Trehal ase Deficiency (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; ammonium chloride; bisphenol A | 8 | 53886946 | 53901113 | Rat | 66 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311284 | Ttc5 | tetratricopeptide repeat domain 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); DNA damage response (ortholog); positive regulation of mRNA catabolic process (ortholog); P ARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 15 | 26466613 | 26484269 | Rat | 85 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3932 | Ucp2 | uncoupling protein 2 | ENCODES a protein that exhibits antiporter activity (ortholog); chloride transmembrane transporter activity (ortholog); GDP binding (ortholog); INVOLVED IN cellular response to amino acid starvation; cellular response to glucose stimulus; cellular response to ho rmone stimulus; PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Acute Liver Failure; Carbon Tetrachloride Poisoning; congestive heart failure; FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-catechin; (R)-lipoic acid; (R)-noradrenaline | 1 | 164251373 | 164257742 | Rat | 551 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305566 | Upp1 | uridine phosphorylase 1 | ENCODES a protein that exhibits deoxyuridine phosphorylase activity (ortholog); identical protein binding (ortholog); thymidine phosphorylase activity (ortholog); INVOLVED IN cellular response to glucose starvation; CMP catabolic process (ortholog); dCMP catabol ic process (ortholog); PARTICIPATES IN pyrimidine metabolic pathway; ASSOCIATED WITH middle cerebral artery infarction; allergic contact dermatitis (ortholog); long QT syndrome (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 14 | 88023155 | 88043036 | Rat | 251 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3963 | Vldlr | very low density lipoprotein receptor | ENCODES a protein that exhibits apolipoprotein binding (ortholog); calcium-dependent protein binding (ortholog); cargo receptor activity (ortholog); INVOLVED IN cellular response to glucose starvation; cellular response to hypoxia; cellular response to insulin s timulus; PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ASSOCIATED WITH Cardiomegaly; Experimental Diabetes Mellitus; focal segmental glomerulosclerosis; FOUND IN apical part of cell; cell surface; perinuclear region of cytoplasm; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 1 | 234239769 | 234272150 | Rat | 350 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304803 | Wdr24 | WD repeat domain 24 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of protein kinase activity (ortholog); PARTICIPA TES IN mTOR signaling pathway; FOUND IN GATOR2 complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 15346835 | 15353384 | Rat | 70 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359718 | Wdr45 | WD repeat domain 45 | ENCODES a protein that exhibits phosphatidylinositol phosphate binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); protein kinase binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to star an>vation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); CEREBRAL-CEREBELLAR-COLOBOMA SYNDROME, X-LINKED (ortholog); Developmental Disabilities (ortholog); FOUND IN phagophore assembly site (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | X | 17448195 | 17454117 | Rat | 131 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305141 | Wdr45b | WD repeat domain 45B | ENCODES a protein that exhibits phosphatidylinositol-3,5-bisphosphate binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); TSC1-TSC2 complex binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); cellular response to starvation (o rtholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorder with Spastic Quadriplegia and Brain Abnormalities with or without Seizures (ortholog); FOUND IN cytosol (ortholog); lysosome (ortholog); phagophore assembly site (ortholog); INTERACTS WITH bisphenol A; Soman; thioacetamide | 10 | 107097655 | 107127839 | Rat | 84 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1592213 | Wdr59 | WD repeat domain 59 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN GATOR2 complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH bisphenol A; glyphosate; vinclozolin | 19 | 56321529 | 56393195 | Rat | 68 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307754 | Wipi1 | WD repeat domain, phosphoinositide interacting 1 | ENCODES a protein that exhibits nuclear androgen receptor binding (ortholog); nuclear estrogen receptor binding (ortholog); phosphatidylinositol-3,5-bisphosphate binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to star ;'>starvation (ortholog); ASSOCIATED WITH cholestasis (ortholog); lipid storage disease (ortholog); FOUND IN autophagosome membrane (ortholog); cytoplasm (ortholog); endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; buspirone | 10 | 95042451 | 95079679 | Rat | 210 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359154 | Wipi2 | WD repeat domain, phosphoinositide interacting 2 | ENCODES a protein that exhibits phosphatidylinositol-3,5-bisphosphate binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagosome maturation (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH INTELLECTUAL DEVELOPMENTAL DISORDER WITH SHORT STATURE AND VARIABLE SKELETAL ANOMALIES (ortholog); FOUND IN autophagosome (ortholog); autophagosome membrane (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 17024876 | 17053306 | Rat | 129 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 69346 | Wnt2b | Wnt family member 2B | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN canonical Wnt signaling pathway (ortholog); cellular response to starvation (ortholog); chondrocyte differentiation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signalin g, canonical pathway; basal cell carcinoma pathway; ASSOCIATED WITH Diarrhea 9 (ortholog); endodermal sinus tumor (ortholog); Failure to Thrive (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil | 2 | 195142573 | 195156945 | Rat | 138 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564788 | Wrn | WRN RecQ like helicase | ENCODES a protein that exhibits chromatin binding; 3'-5' DNA helicase activity (ortholog); 3'-5' exonuclease activity (ortholog); INVOLVED IN base-excision repair (ortholog); cellular response to gamma radiation (ortholog); cellular response to starvation (ortho log); ASSOCIATED WITH breast cancer (ortholog); coronary artery disease (ortholog); diffuse scleroderma (ortholog); FOUND IN centrosome (ortholog); chromosome, telomeric region (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cisplatin | 16 | 65466552 | 65602951 | Rat | 201 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307616 | Yars1 | tyrosyl-tRNA synthetase 1 | ENCODES a protein that exhibits small molecule binding (ortholog); tyrosine-tRNA ligase activity (ortholog); INVOLVED IN response to starvation (ortholog); tyrosyl-tRNA aminoacylation (ortholog); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathw ay; tyrosinemia type III pathway; ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 5 | 146820163 | 146848377 | Rat | 205 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620764 | Yme1l1 | YME1-like 1 ATPase | ENCODES a protein that exhibits ATP-dependent peptidase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to starvation (ortholog); mitochondrial protein catabolic process (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria (ortholog); dilated cardiomyopathy (ortholog); fundus dystrophy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 17 | 90195485 | 90235675 | Rat | 130 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62002 | Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | ENCODES a protein that exhibits receptor tyrosine kinase binding; actin binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to insulin stimulus; cellular response to glucose starvation (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; interleukin-3 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH Constipation (ortholog); COVID-19 (ortholog); Creutzfeldt-Jakob disease (ortholog); FOUND IN presynapse; synapse; vesicle; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 26381106 | 26409466 | Rat | 252 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306776 | Zc3h12a | zinc finger CCCH type containing 12A | ENCODES a protein that exhibits chromatin binding (ortholog); cysteine-type deubiquitinase activity (ortholog); DNA binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); cellular response to chemokine (ortholog); cellular response to glucose star starvation (ortholog); ASSOCIATED WITH Acute Experimental Autoimmune Encephalomyelitis (ortholog); Acute Lung Injury (ortholog); Arterial Occlusive Diseases (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); cytoskeleton (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 5 | 142661193 | 142670051 | Rat | 375 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307795 | Zfyve1 | zinc finger FYVE-type containing 1 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); host-mediate d activation of viral genome replication (ortholog); lipid droplet formation (ortholog); FOUND IN autophagosome (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; all-trans-retinoic acid; bisphenol A | 6 | 108916062 | 108965231 | Rat | 144 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628802 | Retsat | retinol saturase | ENCODES a protein that exhibits all-trans-retinol 13,14-reductase activity (ortholog); INVOLVED IN retinoid metabolic process (ortholog); retinol metabolic process (ortholog); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH Simpson-Golabi-Behmel syndrome type 1 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); nuclear membrane (ortholog); nuclear outer membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 4 | 106211459 | 106220222 | Rat | 191 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9230431 | LOC103692221 | 60S ribosomal protein L17 pseudogene | | 4 | 158999386 | 159000032 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 1595697 | Rpl17-ps1 | ribosomal protein L17, pseudogene 1 | | 2 | 6606697 | 6607280 | Rat | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1593816 | Rpl17-ps7 | ribosomal protein L17, pseudogene 7 | | 2 | 13655468 | 13656290 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 1594381 | Rpl17l3 | ribosomal protein L17 like 3 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN cytosolic ribosome (inferred); large ribosomal subunit (inferred); ribonucleoprotein complex (inferred) | 2 | 38662292 | 38662868 | Rat | 13 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1585025 | Rpl17l5 | ribosomal protein L17 like 5 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN cytosolic ribosome (inferred); large ribosomal subunit (inferred); ribonucleoprotein complex (inferred) | 10 | 45855949 | 45862439 | Rat | 10 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |