Gene: Kl (Klotho) Rattus norvegicus
Symbol: Kl
Name: Klotho
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); fibroblast growth factor receptor binding (ortholog); INVOLVED IN acute inflammatory response; aging; negative regulation of systemic arterial blood pressure; PARTICIPATES IN pentose and glucuronate interconversion pathway; starch and sucrose metabolic pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hyperlipidemias; FOUND IN extracellular exosome (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens : KL (klotho)  HGNC
Mus musculus : Kl (klotho)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.012942,974 - 987,206 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.012929,158 - 972,144 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4123,732,712 - 3,772,371 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1123,732,711 - 3,772,371 (-)NCBI
Celera122,195,730 - 2,234,485 (+)NCBI
Cytogenetic Map12p12NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kl
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 620396
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE