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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of blood circulation
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Accession:GO:1903524 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of blood circulation.
Synonyms:exact_synonym: up regulation of blood circulation;   upregulation of blood circulation
 narrow_synonym: activation of blood circulation
 related_synonym: activation of hemolymph circulation;   positive regulation of hemolymph circulation;   up regulation of hemolymph circulation;   upregulation of hemolymph circulation


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positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:2181229|PMID:12075344)		 Ensembl
RGD		 PMID:12075344 GO_REF:0000107 MGI:2181229 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19707545 RGD:2314476 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Chga chromogranin A involved_in IDA PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP RGD PMID:21620734 RGD:5686387 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19646991)		 Ensembl
RGD		 PMID:19646991 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO
IEA		 (PMID:19646991)
GO_REF:0000107		 RGD
Ensembl		 PMID:19646991 GO_REF:0000107 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022), (MGI:5009116|PMID:21291891) RGD PMID:19127022 PMID:21291891 MGI:3836877 MGI:5009116 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO MGI:3613292|MGI:3613293 (PMID:18678771) RGD PMID:18678771 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886 		JBrowse link
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
positive regulation of cerebral blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp5 dual specificity phosphatase 5 IMP RGD PMID:25397684 RGD:13446412 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
positive regulation of gastric mucosal blood circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:17033095 RGD:12910734 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ptger2 prostaglandin E receptor 2 IDA RGD PMID:10807413 RGD:10043357 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10807413 RGD:10043357 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
positive regulation of heart contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in IMP PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Apln apelin involved_in IMP PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2451290 (PMID:10360172)		 Ensembl
RGD		 PMID:10360172 GO_REF:0000107 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IEA		 (MGI:4829580|PMID:20516643)
GO_REF:0000107		 RGD
Ensembl		 PMID:20516643 GO_REF:0000107 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO UniProtKB:B9EIW1 (PMID:24125847) RGD PMID:24125847 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3829107|PMID:18689573)		 Ensembl
RGD		 PMID:18689573 GO_REF:0000107 MGI:3829107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15896309)		 UniProt
RGD		 PMID:15896309 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857117|MGI:2681791 (PMID:16626672)		 Ensembl
RGD		 PMID:16626672 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adm adrenomedullin involved_in IDA
ISO
IBA		 (PMID:18434369)
GO_REF:0000033		 RGD
GO_Central		 PMID:18434369 PMID:19520650 GO_REF:0000033, RGD:2325635 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adm2 adrenomedullin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331 		JBrowse link
G Adra1a adrenoceptor alpha 1A IMP RGD PMID:22040923 RGD:5688308 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:9089896 RGD:5129112 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Apln apelin IDA RGD PMID:12798955 RGD:1626237 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 IDA RGD PMID:12686462 RGD:13800918 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:18339407 RGD:2300339 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:20060787 RGD:5130949 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:2649896) RGD PMID:2649896 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:2649896)		 Ensembl
RGD		 PMID:2649896 GO_REF:0000107 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Edn3 endothelin 3 involved_in ISO (PMID:2649896) RGD PMID:2649896 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (MGI:5629781|PMID:25557619) RGD PMID:25557619 MGI:5629781 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:3574394 (PMID:15297376) RGD PMID:15297376 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Hrc histidine rich calcium binding protein involved_in ISO UniProtKB:B9EIW1 (PMID:24125847) RGD PMID:24125847 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA		 (PMID:19646991)
GO_REF:0000107		 RGD
Ensembl		 PMID:19646991 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:11853869 UniProt PMID:11853869 RGD:13461753 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO
IEA		 (PMID:19646991)
GO_REF:0000107		 RGD
Ensembl		 PMID:19646991 GO_REF:0000107 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IMP PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 IMP RGD PMID:22569287 RGD:401976380 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:25844489 RGD:13524517 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2183509|MGI:3713774 (PMID:12089338), (PMID:17431507)		 Ensembl
RGD		 PMID:12089338 PMID:17431507 GO_REF:0000107 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO (MGI:5294533|PMID:19796257) RGD PMID:19796257 MGI:5294533 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IMP RGD PMID:17259145 RGD:6484226 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:22113495 RGD:7240568 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:5584094|PMID:23361868) RGD PMID:23361868 MGI:5584094 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:2471579 RGD:2305984 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23954346 RGD:10003031 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:18597948 PMID:12217424 RGD:2306810, RGD:2306871 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237 		JBrowse link
positive regulation of heart rate by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpm1 tropomyosin 1 involved_in ISO (MGI:3802907|PMID:17556658) RGD PMID:17556658 MGI:3802907 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
positive regulation of heart rate by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104774 (PMID:12782680)		 Ensembl
RGD		 PMID:12782680 GO_REF:0000107 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:104773 (PMID:12782680) RGD PMID:12782680 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857120 (PMID:10358009), (PMID:8693001)		 Ensembl
RGD		 PMID:8693001 PMID:10358009 GO_REF:0000107 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1888407 (PMID:10942027)		 Ensembl
RGD		 PMID:10942027 GO_REF:0000107 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
positive regulation of the force of heart contraction by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:19133992 RGD:5129126 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
positive regulation of the force of heart contraction by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104774 (PMID:12595294)		 Ensembl
RGD		 PMID:12595294 GO_REF:0000107 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:104773 (PMID:12595294) RGD PMID:12595294 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857120 (PMID:7761854), (PMID:8693001)		 Ensembl
RGD		 PMID:7761854 PMID:8693001 GO_REF:0000107 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
positive regulation of the force of heart contraction by norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IDA RGD PMID:19133992 RGD:5129126 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    positive regulation of biological process 6649
      positive regulation of multicellular organismal process 1880
        positive regulation of blood circulation 49
          positive regulation of cerebral blood circulation 1
          positive regulation of gastric mucosal blood circulation 3
          positive regulation of heart contraction + 45
Path 2
Term Annotations click to browse term
  biological_process 19694
    multicellular organismal process 8811
      system process 3505
        circulatory system process 613
          blood circulation 584
            regulation of blood circulation 290
              positive regulation of blood circulation 49
                positive regulation of cerebral blood circulation 1
                positive regulation of gastric mucosal blood circulation 3
                positive regulation of heart contraction + 45
paths to the root