Gene: Kcnq1 (potassium voltage-gated channel subfamily Q member 1) Rattus norvegicus
Symbol: Kcnq1
Name: potassium voltage-gated channel subfamily Q member 1
Description: ENCODES a protein that exhibits delayed rectifier potassium channel activity; outward rectifier potassium channel activity; potassium channel activity; INVOLVED IN intestinal absorption; male gonad development; negative regulation of insulin secretion; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abnormal cardiovascular system physiology; decreased body weight; impaired balance; ASSOCIATED WITH Achlorhydria; Deafness; Hypertension; FOUND IN basolateral plasma membrane; cytoplasmic vesicle membrane; integral component of plasma membrane; INTERACTS WITH 17beta-estradiol; ammonium chloride; bis(2-chloroethyl) sulfide
Type: protein-coding
Also known as: IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Kvlqt1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; voltage-gated potassium channel subunit Kv7.1
Allele / Splice: Kcnq1em9Mcwi   Kcnq1em14Mcwi   Kcnq1dfk  
Genetic Models: WTC-Kcnq1dfkKyo SS-Kcnq1em14Mcwi SS-Kcnq1em9Mcwi
Is Marker For: Strains:   WTC-Kcnq1dfkKyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01216,293,087 - 216,630,339 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01223,154,713 - 223,490,458 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41203,383,401 - 203,803,687 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11203,536,853 - 203,957,140 (+)NCBI
Celera1195,860,199 - 196,193,008 (+)NCBI
Cytogenetic Map1q42NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kcnq1
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 621503
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-04-11
Status: ACTIVE