Gene: Kcnq1 (potassium voltage-gated channel, KQT-like subfamily, member 1)  Rattus norvegicus

Symbol: Kcnq1
Name: potassium voltage-gated channel, KQT-like subfamily, member 1
Description: ENCODES a protein that exhibits outward rectifier potassium channel activity; potassium channel activity; protein homodimerization activity; INVOLVED IN male gonad development; negative regulation of insulin secretion; positive regulation of gastric acid secretion; ASSOCIATED WITH abnormal cardiovascular system physiology; decreased body weight; impaired balance; ASSOCIATED WITH Achlorhydria; Deafness; Hypertension; FOUND IN basolateral plasma membrane; cytoplasmic vesicle membrane; integral to plasma membrane; INTERACTS WITH ammonium chloride; bis(2-chloroethyl) sulfide; bis(2-ethylhexyl) phthalate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Kvlqt1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; voltage-gated potassium channel subunit Kv7.1
Orthologs: Homo sapiens : KCNQ1 (potassium voltage-gated channel, KQT-like subfamily, member 1)  HGNC
Mus musculus : Kcnq1 (potassium voltage-gated channel, subfamily Q, member 1)  MGI
Allele / Splice: Kcnq1em9Mcwi   Kcnq1em14Mcwi  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map1q41 NCBI
RGSC Genome Assembly v5.01223,154,713 - 223,490,458+NCBI
RGSC Genome Assembly v3.41203,383,401 - 203,803,687+NCBI
Rat Celera Assembly1195,860,199 - 196,193,008+NCBI
Genome Assembly 3.11203,536,853 - 203,957,140+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)
Related Rat Strains

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnq1
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RGD Object Information
RGD ID: 621503
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2013-05-07
Status: ACTIVE