Gene: Kcnq1 (potassium voltage-gated channel subfamily Q member 1) Rattus norvegicus
Symbol: Kcnq1
Name: potassium voltage-gated channel subfamily Q member 1
Description: ENCODES a protein that exhibits delayed rectifier potassium channel activity; outward rectifier potassium channel activity; potassium channel activity; INVOLVED IN intestinal absorption; male gonad development; negative regulation of insulin secretion; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abnormal cardiovascular system physiology; decreased body weight; impaired balance; ASSOCIATED WITH Achlorhydria; Deafness; Hypertension; FOUND IN basolateral plasma membrane; cytoplasmic vesicle membrane; integral component of plasma membrane; INTERACTS WITH 17beta-estradiol; ammonium chloride; bis(2-chloroethyl) sulfide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Kvlqt1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; voltage-gated potassium channel subunit Kv7.1
Orthologs:
Allele / Splice: Kcnq1em9Mcwi   Kcnq1em14Mcwi  
Is Marker For: Strains:   WTC-Kcnq1dfkKyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01216,293,087 - 216,630,339 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01223,154,713 - 223,490,458 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41203,383,401 - 203,803,687 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11203,536,853 - 203,957,140 (+)NCBI
Celera1195,860,199 - 196,193,008 (+)NCBI
Cytogenetic Map1q41NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnq1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621503
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-06
Status: ACTIVE