Gene: Slc1a1 (solute carrier family 1 member 1) Rattus norvegicus
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Symbol: Slc1a1
Name: solute carrier family 1 member 1
Description: ENCODES a protein that exhibits glutamate binding; glutamate:sodium symporter activity; L-glutamate transmembrane transporter activity; INVOLVED IN L-glutamate transport; protein homooligomerization; chloride transmembrane transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Atrophy (ortholog); brain disease (ortholog); Brain Diseases (ortholog); FOUND IN apical plasma membrane (ortholog); extracellular exosome (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1-naphthyl isothiocyanate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Eaac1; Eaat3; excitatory amino acid carrier 1; excitatory amino acid transporter 3; excitatory amino acid transporter-3; excitatory amino-acid carrier 1; REAAC1; sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Solute carrier family 1 A1 (brain glutamate transporter); solute carrier family 1, member 1
Orthologs:
Homo sapiens (human) : SLC1A1 (solute carrier family 1 member 1)  HGNC  AGR
Mus musculus (house mouse) : Slc1a1 (solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Slc1a1 (solute carrier family 1 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC1A1 (solute carrier family 1 member 1)
Canis lupus familiaris (dog) : SLC1A1 (solute carrier family 1 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc1a1 (solute carrier family 1 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01246,955,017 - 247,035,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01254,195,480 - 254,274,919 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,469,746 - 232,549,584 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11232,633,737 - 232,715,504 (+)NCBI
Celera1223,704,163 - 223,782,895 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc1a1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3696
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE