ONTOLOGY REPORT - ANNOTATIONS

Term:focal adhesion assembly
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Accession:GO:0048041 term browser browse the term
Definition:The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
Synonyms:related_synonym: focal adhesion formation

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focal adhesion assembly term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Actn1 actinin, alpha 1 GBrowse link ISO 6 103,188,593 103,282,873 RGD:1624291 RGD
G Actn1 actinin, alpha 1 GBrowse link IEA 6 103,188,593 103,282,873 RGD:1600115 ENSEMBL
G Actn2 actinin alpha 2 GBrowse link ISO 17 68,705,160 68,773,261 RGD:1624291 RGD
G Actn2 actinin alpha 2 GBrowse link IEA 17 68,705,160 68,773,261 RGD:1600115 ENSEMBL
G Actn3 actinin alpha 3 GBrowse link ISO 1 207,475,569 207,492,267 RGD:1624291 RGD
G Ajuba ajuba LIM protein GBrowse link ISO 15 32,627,633 32,637,861 RGD:1624291 RGD
G Ajuba ajuba LIM protein GBrowse link IEA 15 32,627,633 32,637,861 RGD:1600115 ENSEMBL
G Arhgap6 Rho GTPase activating protein 6 GBrowse link ISO X 45,638,826 46,180,012 RGD:1624291 RGD
G Arhgap6 Rho GTPase activating protein 6 GBrowse link IEA X 45,638,826 46,180,012 RGD:1600115 ENSEMBL
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link ISO 13 12,730,736 12,905,108 RGD:1624291 RGD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link IEA 13 12,730,736 12,905,108 RGD:1600115 ENSEMBL
G Dlc1 deleted in liver cancer 1 GBrowse link ISO 16 59,312,930 59,355,129 RGD:1624291 RGD
G Dlc1 deleted in liver cancer 1 GBrowse link IEA 16 59,312,930 59,355,129 RGD:1600115 ENSEMBL
G Pdpk1 3-phosphoinositide dependent protein kinase-1 GBrowse link IMP 10 13,329,708 13,394,080 RGD:1581775 RGD
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha GBrowse link IEA 2 189,962,527 190,005,684 RGD:1600115 ENSEMBL
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha GBrowse link ISO 2 189,962,527 190,005,684 RGD:1624291 RGD
G Ptk2b protein tyrosine kinase 2 beta GBrowse link IMP 15 45,589,222 45,717,866 RGD:1581775 RGD
G Ptprk protein tyrosine phosphatase, receptor type, K GBrowse link ISO 1 17,328,563 17,752,200 RGD:1624291 RGD
G Pxn paxillin GBrowse link ISO 12 42,322,193 42,370,507 RGD:1624291 RGD
G Pxn paxillin GBrowse link IEA 12 42,322,193 42,370,507 RGD:1600115 ENSEMBL
G Sorbs1 sorbin and SH3 domain containing 1 GBrowse link ISO 1 245,419,532 245,527,846 RGD:1624291 RGD
G Sorbs1 sorbin and SH3 domain containing 1 GBrowse link ISS 1 245,419,532 245,527,846 RGD:1600115 UniProtKB
G Taok2 TAO kinase 2 GBrowse link ISO 1 186,049,010 186,063,423 RGD:1624291 RGD
G Tesk2 testis-specific kinase 2 GBrowse link IMP 5 137,014,118 137,100,429 RGD:727318 UniProtKB
G Thy1 Thy-1 cell surface antigen GBrowse link IDA 8 47,027,721 47,031,857 UniProtKB
negative regulation of focal adhesion assembly term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Acvrl1 activin A receptor type II-like 1 GBrowse link ISO 7 139,873,596 139,884,675 RGD:1624291 RGD
G Acvrl1 activin A receptor type II-like 1 GBrowse link IEA 7 139,873,596 139,884,675 RGD:1600115 ENSEMBL
G Apod apolipoprotein D ISO RGD:1624291 RGD
G Apod apolipoprotein D ISS RGD:1600115 UniProtKB
G Arhgap6 Rho GTPase activating protein 6 GBrowse link ISO X 45,638,826 46,180,012 RGD:1624291 RGD
G Arhgap6 Rho GTPase activating protein 6 GBrowse link IEA X 45,638,826 46,180,012 RGD:1600115 ENSEMBL
G Itgb1bp1 integrin beta 1 binding protein 1 GBrowse link ISO 6 41,830,110 41,844,514 RGD:1624291 RGD
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) GBrowse link IDA 15 32,493,852 32,503,077 RGD:1582604 RGD
G Pten phosphatase and tensin homolog GBrowse link ISO 1 236,771,027 236,837,261 RGD:1624291 RGD
G Pten phosphatase and tensin homolog GBrowse link IEA 1 236,771,027 236,837,261 RGD:1600115 ENSEMBL
G Src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) GBrowse link IMP 3 148,157,256 148,170,524 BHF-UCL
positive regulation of focal adhesion assembly term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Epb4.1l5 erythrocyte protein band 4.1-like 5 GBrowse link IEA 13 32,373,377 32,426,745 RGD:1600115 ENSEMBL
G Hrg histidine-rich glycoprotein GBrowse link ISO 11 80,248,578 80,264,179 RGD:1624291 RGD
G Hrg histidine-rich glycoprotein GBrowse link ISO 11 80,248,578 80,264,179 RGD:1624291 RGD
G Hrg histidine-rich glycoprotein GBrowse link ISS 11 80,248,578 80,264,179 RGD:1600115 UniProtKB
G Kdr kinase insert domain receptor ISO RGD:1624291 RGD
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F GBrowse link ISO 11 86,086,968 86,114,278 RGD:1624291 RGD
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F GBrowse link ISS 11 86,086,968 86,114,278 RGD:1600115 UniProtKB
G Ptprj protein tyrosine phosphatase, receptor type, J GBrowse link ISO 3 74,796,764 74,935,540 RGD:1624291 RGD
G Sdc4 syndecan 4 GBrowse link IMP 3 155,446,138 155,464,825 RGD:2312327 RGD
G Smad3 SMAD family member 3 GBrowse link IDA 8 67,803,909 67,952,056 RGD:2300418 RGD
G Tek TEK tyrosine kinase, endothelial GBrowse link ISO 5 115,047,195 115,196,172 RGD:1624291 RGD
G Tek TEK tyrosine kinase, endothelial GBrowse link IEA 5 115,047,195 115,196,172 RGD:1600115 ENSEMBL
G Tsc1 tuberous sclerosis 1 GBrowse link ISO 3 7,645,313 7,672,944 RGD:1624291 RGD
G Tsc1 tuberous sclerosis 1 GBrowse link IEA 3 7,645,313 7,672,944 RGD:1600115 ENSEMBL
G Vegfa vascular endothelial growth factor A GBrowse link ISO 9 10,520,730 10,536,071 RGD:1624291 RGD
G Vegfa vascular endothelial growth factor A GBrowse link IEA 9 10,520,730 10,536,071 RGD:1600115 ENSEMBL
G Vegfa vascular endothelial growth factor A GBrowse link ISS 9 10,520,730 10,536,071 RGD:1600115 UniProtKB
regulation of focal adhesion assembly term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Efna5 ephrin A5 GBrowse link ISO 9 101,227,615 101,532,696 RGD:1624291 RGD
G Efna5 ephrin A5 GBrowse link IEA 9 101,227,615 101,532,696 RGD:1600115 ENSEMBL
G Efna5 ephrin A5 GBrowse link ISS 9 101,227,615 101,532,696 RGD:1600115 UniProtKB
G Epha3 Eph receptor A3 GBrowse link ISO 11 696,185 1,033,287 RGD:1624291 RGD
G Epha3 Eph receptor A3 GBrowse link IEA 11 696,185 1,033,287 RGD:1600115 ENSEMBL
G Epha3 Eph receptor A3 GBrowse link ISS 11 696,185 1,033,287 RGD:1600115 UniProtKB
G Gpm6b glycoprotein m6b GBrowse link IEA X 48,746,584 48,788,414 RGD:1600115 ENSEMBL
G Gpm6b glycoprotein m6b GBrowse link ISS X 48,746,584 48,788,414 RGD:1600115 UniProtKB
G Grem1 gremlin 1 GBrowse link ISO 3 99,597,201 99,608,935 RGD:1624291 RGD
G Grem1 gremlin 1 GBrowse link IEA 3 99,597,201 99,608,935 RGD:1600115 ENSEMBL
G Macf1 microtubule-actin crosslinking factor 1 GBrowse link ISS 5 142,659,726 142,986,873 RGD:1600115 UniProtKB
G Tsc1 tuberous sclerosis 1 GBrowse link IMP 3 7,645,313 7,672,944 RGD:1601406 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    biological adhesion 1677
      cell adhesion 1661
        cell-substrate adhesion 385
          cell-matrix adhesion 216
            focal adhesion assembly 65
              negative regulation of focal adhesion assembly 11
              positive regulation of focal adhesion assembly 17
              regulation of focal adhesion assembly + 40
Path 2
Term Annotations click to browse term
  biological_process 135967
    cellular component organization or biogenesis 12039
      cellular component organization 11786
        cell junction organization 250
          cell-cell junction organization 231
            adherens junction organization 88
              adherens junction assembly 77
                focal adhesion assembly 65
                  negative regulation of focal adhesion assembly 11
                  positive regulation of focal adhesion assembly 17
                  regulation of focal adhesion assembly + 40
paths to the root

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