Gene: Actn2 (actinin alpha 2) Rattus norvegicus
Symbol: Actn2
Name: actinin alpha 2
Description: ENCODES a protein that exhibits actin filament binding (ortholog); cytoskeletal protein binding (ortholog); FATZ binding (ortholog); INVOLVED IN actin filament uncapping (ortholog); cardiac muscle cell development (ortholog); establishment of protein localization to plasma membrane (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; Entamoeba histolyca infection pathway; systemic lupus erythematosus pathway; ASSOCIATED WITH Cardiomyopathies (ortholog); Cardiomyopathy, Dilated (ortholog); Cardiomyopathy, Dilated, 1AA (ortholog); FOUND IN cortical actin cytoskeleton; extracellular exosome (ortholog); filopodium (ortholog); INTERACTS WITH benzo[a]pyrene; bis(2-ethylhexyl) phthalate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-actinin-2; LOC291245
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01766,304,530 - 66,397,647 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01768,050,946 - 68,143,522 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41768,705,160 - 68,773,261 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11768,681,756 - 68,784,094 (+)NCBI
Celera1762,323,048 - 62,390,681 (-)NCBI
Cytogenetic Map17q12.1NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Actn2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1308097
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2016-05-10
Status: ACTIVE