Gene: Actn2 (actinin alpha 2) Rattus norvegicus
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Symbol: Actn2
Name: actinin alpha 2
Description: ENCODES a protein that exhibits actin filament binding (ortholog); cytoskeletal protein binding (ortholog); FATZ binding (ortholog); INVOLVED IN actin filament uncapping (ortholog); cardiac muscle cell development (ortholog); focal adhesion assembly (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; Entamoeba histolyca infection pathway; systemic lupus erythematosus pathway; ASSOCIATED WITH Cardiomyopathies (ortholog); cardiomyopathy (ortholog); Cardiomyopathy, Dilated (ortholog); FOUND IN cortical actin cytoskeleton; extracellular exosome (ortholog); filopodium (ortholog); INTERACTS WITH 17beta-estradiol; benzo[a]pyrene; bis(2-ethylhexyl) phthalate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-actinin-2; LOC291245
Orthologs:
Homo sapiens (human) : ACTN2 (actinin alpha 2)  HGNC  AGR
Mus musculus (house mouse) : Actn2 (actinin alpha 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Actn2 (actinin alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTN2 (actinin alpha 2)
Canis lupus familiaris (dog) : ACTN2 (actinin alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actn2 (actinin alpha 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01766,304,530 - 66,397,647 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01768,050,946 - 68,143,522 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41768,705,160 - 68,773,261 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11768,681,756 - 68,784,094 (+)NCBI
Celera1762,323,048 - 62,390,681 (-)NCBI
Cytogenetic Map17q12.1NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Actn2
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 1308097
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-10
Status: ACTIVE