Gene: Actn2 (actinin alpha 2) Rattus norvegicus
Symbol: Actn2
Name: actinin alpha 2
Description: ENCODES a protein that exhibits actin filament binding (ortholog); cytoskeletal protein binding (ortholog); FATZ binding (ortholog); INVOLVED IN focal adhesion assembly (ortholog); microspike assembly (ortholog); muscle contraction (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; Entamoeba histolyca infection pathway; systemic lupus erythematosus pathway; ASSOCIATED WITH Cardiomyopathies (ortholog); Cardiomyopathy, Dilated, 1AA (ortholog); Ventricular Fibrillation (ortholog); FOUND IN cortical actin cytoskeleton; extracellular exosome (ortholog); filopodium (ortholog); INTERACTS WITH benzo[a]pyrene; bis(2-ethylhexyl) phthalate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-actinin-2; LOC291245
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01766,304,530 - 66,397,647-NCBI
Rat Cytogenetic Map17q12.1 NCBI
RGSC Genome Assembly v5.01768,050,946 - 68,143,522-NCBI
RGSC Genome Assembly v3.41768,705,160 - 68,773,261+NCBI
Rat Celera Assembly1762,323,048 - 62,390,681-NCBI
Genome Assembly 3.11768,681,756 - 68,784,094+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Actn2
Entrez Gene
Ensembl Gene
Genome Browser
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Vista + UCSC

RGD Object Information
RGD ID: 1308097
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-03-18
Status: ACTIVE