Gene: Bcr (breakpoint cluster region) Rattus norvegicus
Symbol: Bcr
Name: breakpoint cluster region
Description: ENCODES a protein that exhibits enzyme binding; GTPase activator activity (ortholog); INVOLVED IN platelet-derived growth factor receptor signaling pathway; protein autophosphorylation; actin cytoskeleton organization (ortholog); PARTICIPATES IN chronic myeloid leukemia pathway; ASSOCIATED WITH Leukemia, Myelogenous, Chronic, BCR-ABL Positive (ortholog); Precursor Cell Lymphoblastic Leukemia-Lymphoma (ortholog); FOUND IN cytoplasm; cytosol (ortholog); extracellular exosome (ortholog); INTERACTS WITH bisphenol A; chlorpyrifos; dexamethasone
Type: protein-coding
RefSeq Status: MODEL
Also known as: breakpoint cluster region homolog; breakpoint cluster region protein; LOC309696
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.02014,421,250 - 14,546,402-NCBI
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.02016,604,476 - 16,729,388-NCBI
RGSC Genome Assembly v3.42013,972,773 - 14,097,816-NCBI
Rat Celera Assembly2014,954,516 - 15,079,932-NCBI
Genome Assembly 3.12013,973,364 - 14,098,043-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Bcr
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1307993
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-11-10
Status: ACTIVE