Gene: Grem1 (gremlin 1)  Rattus norvegicus

Symbol: Grem1
Name: gremlin 1
Description: ENCODES a protein that exhibits protein tyrosine kinase activator activity (ortholog); receptor agonist activity (ortholog); vascular endothelial growth factor receptor 2 binding (ortholog); INVOLVED IN apoptotic process; negative regulation of cell growth; negative regulation of leukocyte chemotaxis; PARTICIPATES IN Bone morphogenetic proteins signaling pathway; FOUND IN cell surface; extracellular space; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2,4-trimethylbenzene; 2-amino-2-deoxy-D-glucopyranose
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cktsf1b1; cysteine knot superfamily 1, BMP antagonist 1; down-regulated in mos-transformed cells; down-regulated in Mos-transformed cells protein; drm; gremlin 1 homolog, cysteine knot superfamily; gremlin 1 homolog, cysteine knot superfamily (Xenopus laevis); gremlin 1, cysteine knot superfamily, homolog; gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis); gremlin-1
Orthologs: Homo sapiens : GREM1 (gremlin 1, DAN family BMP antagonist)  HGNC
Mus musculus : Grem1 (gremlin 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map3q34 NCBI
RGSC Genome Assembly v5.03111,779,965 - 111,791,645-NCBI
RGSC Genome Assembly v3.4399,597,201 - 99,608,935-NCBI
Rat Celera Assembly399,483,712 - 99,495,442-NCBI
Genome Assembly 3.1399,493,630 - 99,505,363-NCBI
Model

Launch Genome Browser (GBrowse)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Grem1
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Ensembl Gene
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RGD Object Information
RGD ID: 2359
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE