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ONTOLOGY REPORT - ANNOTATIONS

Term:response to hyperoxia
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Accession:GO:0055093 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
Synonyms:exact_synonym: response to hyperoxic stress;   response to increased oxygen tension


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response to hyperoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IEP RGD PMID:17343756 RGD:1625339 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEP RGD PMID:16782756 RGD:2306340 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IEP RGD PMID:12490039 RGD:4890420 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP RGD PMID:15821016 RGD:4891113 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP RGD PMID:20157446 RGD:5128796 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Cat catalase IEP RGD PMID:19895324 RGD:5130747 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IEP RGD PMID:21404274 RGD:5130888 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 IEP RGD PMID:18082050 RGD:2289663 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:18082050 RGD:2289663 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Col1a1 collagen type I alpha 1 chain IEP RGD PMID:11918316 RGD:8552772 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP RGD PMID:16497785 RGD:2306657 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Eln elastin IEP RGD PMID:9609733 RGD:9585726 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Epo erythropoietin IEP RGD PMID:19768476 RGD:2313637 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Hdac1 histone deacetylase 1 IEP RGD PMID:21905265 RGD:9590253 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:21905265 RGD:9590253 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Il18 interleukin 18 IEP RGD PMID:19672068 RGD:4889402 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IEP RGD PMID:16735674 RGD:8693740 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:19099751 RGD:5129684 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:19099751 RGD:5129684 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 IEP RGD PMID:18481000 RGD:2298955 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 IEP RGD PMID:18481000 RGD:2298955 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP RGD PMID:18481000 RGD:2298955 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEP RGD PMID:19337906 RGD:2314428 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Nos3 nitric oxide synthase 3 IEP RGD PMID:17937862 RGD:2292125 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:15722379 RGD:1580851 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP RGD PMID:15722379 RGD:1580851 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP RGD PMID:19411306 RGD:9999157 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdpn podoplanin IEP RGD PMID:12922978 RGD:1302251 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Plau plasminogen activator, urokinase IEP RGD PMID:19099788 RGD:4143526 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plcd1 phospholipase C, delta 1 IEP RGD PMID:12850505 RGD:1299008 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186 		JBrowse link
G Polb DNA polymerase beta IEP RGD PMID:8786668 RGD:8694108 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit IEP RGD PMID:8786668 RGD:8694108 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Sell selectin L IEP RGD PMID:12730074 RGD:5686287 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:19099788 RGD:4143526 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sftpa1 surfactant protein A1 IEP RGD PMID:11472975 RGD:4143429 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sftpb surfactant protein B IEP RGD PMID:11472975 RGD:4143429 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpc surfactant protein C IEP RGD PMID:11472975 RGD:4143429 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Sftpd surfactant protein D IEP RGD PMID:11472975 RGD:4143429 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 IEP RGD PMID:25089378 RGD:151361121 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344 (PMID:11796207) RGD PMID:11796207 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tp53 tumor protein p53 IEP RGD PMID:18337831 RGD:2290551 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP RGD PMID:20493230 RGD:5133717 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Txnrd2 thioredoxin reductase 2 IEP RGD PMID:20493230 RGD:5133717 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156 		JBrowse link
G Wnt5a Wnt family member 5A IEP RGD PMID:17911382 RGD:2304247 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
cellular response to hyperoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20543840)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20543840 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:21382479)
GO_REF:0000107		 RGD
Ensembl		 PMID:21382479 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta IEP RGD PMID:23039253 RGD:9589076 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:15734424 RGD:5131935 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:21382479) RGD PMID:21382479 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20543840)		 UniProt
RGD		 PMID:20543840 GO_REF:0000024 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3616995 (PMID:19661248)		 Ensembl
RGD		 PMID:19661248 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP RGD PMID:22444276 RGD:8553189 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Txn1 thioredoxin 1 IEP RGD PMID:21505996 RGD:5133704 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP RGD PMID:21505996 RGD:5133704 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10511
      response to stress 4181
        response to hyperoxia 53
          cellular response to hyperoxia 10
Path 2
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10511
      response to abiotic stimulus 1578
        response to oxygen levels 607
          response to increased oxygen levels 61
            response to hyperoxia 53
              cellular response to hyperoxia 10
paths to the root