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ONTOLOGY REPORT - ANNOTATIONS

Term:signaling receptor complex adaptor activity
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Accession:GO:0030159 term browser browse the term
Definition:The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.
Synonyms:exact_synonym: receptor signaling complex scaffold activity;   receptor signaling complex scaffold protein activity;   receptor signalling complex adaptor activity;   receptor signalling complex scaffold activity


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signaling receptor complex adaptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crk CRK proto-oncogene, adaptor protein enables ISO UniProtKB:P22682 (MGI:1201213|PMID:9447983) RGD PMID:9447983 MGI:1201213 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Gnb1 G protein subunit beta 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gnb2 G protein subunit beta 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019 		JBrowse link
G Gnb3 G protein subunit beta 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173 		JBrowse link
G Gnb4 G protein subunit beta 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579 		JBrowse link
G Gnb5 G protein subunit beta 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:76,076,120...76,105,069
Ensembl chr 8:76,073,306...76,105,069 		JBrowse link
G Grb10 growth factor receptor bound protein 10 enables IEA
ISO		 GO_REF:0000107
UniProtKB:P15208 (MGI:3847873|PMID:15664450)		 Ensembl
RGD		 PMID:15664450 GO_REF:0000107 MGI:3847873 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Irs1 insulin receptor substrate 1 enables IEA
ISO		 GO_REF:0000107
(PMID:7493946)		 Ensembl
RGD		 PMID:7493946 GO_REF:0000107 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Lat linker for activation of T cells enables ISO (PMID:9489702) RGD PMID:9489702 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 enables ISO
IEA		 (PMID:15166224)
GO_REF:0000107		 RGD
Ensembl		 PMID:15166224 GO_REF:0000107 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 enables ISO (PMID:22899650) RGD PMID:22899650 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 enables ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:11526121)		 UniProt
GO_Central
Ensembl
RGD		 PMID:11526121 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Nup62 nucleoporin 62 enables ISO
ISS		 (PMID:11244088)
GO_REF:0000024		 RGD
UniProt		 PMID:11244088 GO_REF:0000024 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 enables NAS PMID:8940095 UniProt PMID:8940095 RGD:632670 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 enables ISO
IEA		 UniProtKB:P06213|UniProtKB:P35568 (PMID:7493946)
GO_REF:0000107		 RGD
Ensembl		 PMID:7493946 GO_REF:0000107 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 enables IDA PMID:19319189 UniProt PMID:19319189 RGD:8554645 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 enables ISO UniProtKB:P05532 (MGI:3041996|PMID:14612394) RGD PMID:14612394 MGI:3041996 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 IDA RGD PMID:10958799 RGD:633972 NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824 		JBrowse link
G Shb SH2 domain containing adaptor protein B enables ISO (PMID:8302579) RGD PMID:8302579 NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 enables ISO
IEA		 (PMID:11374898)
GO_REF:0000107
UniProtKB:P22681|UniProtKB:P22682 (MGI:1201213|PMID:9447983)		 RGD
Ensembl		 PMID:9447983 PMID:11374898 GO_REF:0000107 MGI:1201213 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Spag9 sperm associated antigen 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797 		JBrowse link
G Spata2 spermatogenesis associated 2 enables ISO (PMID:27545878) RGD PMID:27545878 NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705 		JBrowse link
synaptic receptor adaptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Homer2 homer scaffold protein 2 enables IEA
ISO		 GO_REF:0000107
(PMID:10493740)		 Ensembl
RGD		 PMID:10493740 GO_REF:0000107 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 enables IDA
ISO
IBA		 PMID:10433269
(MGI:3775591|PMID:18272690)
GO_REF:0000033		 RGD
GO_Central		 PMID:18272690 PMID:10433269 GO_REF:0000033 MGI:3775591, RGD:8554380 NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 enables IDA
IBA		 PMID:10433269
GO_REF:0000033		 GO_Central PMID:10433269 GO_REF:0000033, RGD:8554380 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dok2 docking protein 2 enables ISO PR:P25911 (PMID:10428862) RGD PMID:10428862 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 enables IBA
ISO		 GO_REF:0000033
(PMID:9182757)		 GO_Central
RGD		 PMID:9182757 GO_REF:0000033 NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382 		JBrowse link
G Gab2 GRB2-associated binding protein 2 enables ISO
IBA
IEA
ISS		 (PMID:19172738)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:19172738 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Grb2 growth factor receptor bound protein 2 enables IEA
ISO		 GO_REF:0000107
MGI:108088 (PMID:17881575)		 Ensembl
RGD		 PMID:17881575 GO_REF:0000107 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Irs1 insulin receptor substrate 1 enables IMP
ISO		 PMID:18285345
(PMID:11784871), (PMID:12483226), (PMID:8649419)		 RGD PMID:8649419 PMID:11784871 PMID:12483226 PMID:18285345 RGD:8553881 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 enables ISO (PMID:7534300) RGD PMID:7534300 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 TAS RGD PMID:11859092 RGD:625637 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:181,048,622...181,057,036
Ensembl chr 1:181,048,623...181,056,579 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 enables IBA
ISO		 GO_REF:0000033
(PMID:10196204)		 GO_Central
RGD		 PMID:10196204 GO_REF:0000033 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Shc1 SHC adaptor protein 1 enables IEA
ISO		 GO_REF:0000107
(PMID:12483226), (PMID:7799946)		 Ensembl
RGD		 PMID:7799946 PMID:12483226 GO_REF:0000107 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Stap1 signal transducing adaptor family member 1 enables ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Tradd TNFRSF1A-associated via death domain enables ISO
IBA		 UniProtKB:Q13546 (PMID:8612133)
GO_REF:0000033		 RGD
GO_Central		 PMID:8612133 GO_REF:0000033 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    molecular adaptor activity 1140
      protein-macromolecule adaptor activity 984
        signaling adaptor activity 105
          signaling receptor complex adaptor activity 38
            synaptic receptor adaptor activity 4
            transmembrane receptor protein tyrosine kinase adaptor activity 13
paths to the root