ONTOLOGY REPORT - ANNOTATIONS

Term:binding, bridging
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Accession:GO:0060090 term browser browse the term
Definition:The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
Synonyms:exact_synonym: molecular adaptor activity

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binding, bridging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gas6 growth arrest specific 6 GBrowse link ISO 16 80,900,159 80,930,929 RGD:1624291 RGD
G Gas6 growth arrest specific 6 GBrowse link ISS 16 80,900,159 80,930,929 RGD:1600115 UniProtKB
G Pdcd6 programmed cell death 6 GBrowse link ISO 1 29,769,911 29,785,577 RGD:1624291 RGD
G Pdcd6 programmed cell death 6 GBrowse link IEA 1 29,769,911 29,785,577 RGD:1600115 ENSEMBL
G Tradd TNFRSF1A-associated via death domain GBrowse link IEA 19 35,073,150 35,075,251 RGD:1600115 ENSEMBL
G Tradd TNFRSF1A-associated via death domain GBrowse link ISO 19 35,073,150 35,075,251 RGD:1624291 RGD
CCC codon-amino acid adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G mt-Tp mitochondrially encoded tRNA proline GBrowse link IDA MT 15,348 15,415 RGD:2317000 RGD
clathrin adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Arrb1 arrestin, beta 1 GBrowse link IDA 1 156,871,564 156,937,540 RGD:1601545 BHF-UCL
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link ISO 2 55,714,874 55,736,370 RGD:1624291 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
cytoskeletal adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ank1 ankyrin 1, erythrocytic GBrowse link ISO 16 73,333,564 73,437,926 RGD:1624291 RGD
G Arhgap26 Rho GTPase activating protein 26 GBrowse link IEA 18 31,934,753 32,327,551 RGD:1600115 InterPro
G Baiap2 BAI1-associated protein 2 GBrowse link IEA 10 109,351,201 109,413,703 RGD:1600115 InterPro
G Baiap2l1 BAI1-associated protein 2-like 1 GBrowse link IEA 12 10,584,749 10,668,948 RGD:1600115 InterPro
G Baiap2l2 BAI1-associated protein 2-like 2 GBrowse link IEA 7 117,240,190 117,265,958 RGD:1600115 InterPro
G Bicd1 bicaudal D homolog 1 (Drosophila) GBrowse link IEA 4 186,922,060 187,069,288 RGD:1600115 ENSEMBL
G Bicd1 bicaudal D homolog 1 (Drosophila) GBrowse link ISO 4 186,922,060 187,069,288 RGD:1624291 RGD
G Gas2l1 growth arrest-specific 2 like 1 GBrowse link IEA 14 85,716,617 85,726,368 RGD:1600115 ENSEMBL
G Gas2l2 growth arrest-specific 2 like 2 GBrowse link ISS 10 71,505,385 71,512,429 RGD:1600115 UniProtKB
G Gas2l2 growth arrest-specific 2 like 2 GBrowse link ISO 10 71,505,385 71,512,429 RGD:1624291 RGD
G Mtss1 metastasis suppressor 1 GBrowse link IEA 7 95,808,266 95,947,927 RGD:1600115 InterPro
G Mtss1l metastasis suppressor 1-like GBrowse link IEA 19 40,640,947 40,661,240 RGD:1600115 InterPro
JAK pathway signal transduction adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Sh2b2 SH2B adaptor protein 2 GBrowse link ISO 12 21,544,434 21,572,232 RGD:1624291 RGD
MAP-kinase scaffold activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Dusp19 dual specificity phosphatase 19 GBrowse link ISO 3 63,473,333 63,485,843 RGD:1624291 RGD
G Ksr1 kinase suppressor of ras 1 GBrowse link ISO 10 65,186,444 65,322,155 RGD:1624291 RGD
G Ksr2 kinase suppressor of ras 2 GBrowse link ISO 12 39,998,030 40,376,125 RGD:1624291 RGD
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 GBrowse link IMP 3 76,781,504 76,790,661 RGD:2298766 RGD
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 GBrowse link ISO 3 76,781,504 76,790,661 RGD:1624291 RGD
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 GBrowse link ISO 10 14,147,895 14,186,277 RGD:1624291 RGD
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 GBrowse link ISO 10 14,147,895 14,186,277 RGD:1624291 RGD
G Sh3rf1 SH3 domain containing ring finger 1 GBrowse link ISO 16 32,054,773 32,215,987 RGD:1624291 RGD
G Sh3rf1 SH3 domain containing ring finger 1 GBrowse link IEA 16 32,054,773 32,215,987 RGD:1600115 ENSEMBL
protein binding, bridging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ank2 ankyrin 2, neuronal GBrowse link ISO 2 224,182,431 224,501,751 RGD:1624291 RGD
G Ank2 ankyrin 2, neuronal GBrowse link ISO 2 224,182,431 224,501,751 RGD:1624291 RGD
G Anxa1 annexin A1 GBrowse link ISO 1 223,478,436 223,494,455 RGD:1624291 RGD
G Anxa1 annexin A1 GBrowse link IEA 1 223,478,436 223,494,455 RGD:1600115 ENSEMBL
G Cbx5 chromobox homolog 5 GBrowse link ISO 7 142,107,922 142,125,543 RGD:1624291 RGD
G Cbx5 chromobox homolog 5 GBrowse link IEA 7 142,107,922 142,125,543 RGD:1600115 ENSEMBL
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 GBrowse link ISO 5 152,972,551 152,983,208 RGD:1624291 RGD
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 GBrowse link IEA 5 152,972,551 152,983,208 RGD:1600115 ENSEMBL
G Cnn3 calponin 3, acidic GBrowse link NAS 2 218,044,803 218,075,914 RGD:727577 RGD
G Col1a2 collagen, type I, alpha 2 GBrowse link ISO 4 29,393,645 29,428,572 RGD:1624291 RGD
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link IEA 7 32,504,279 32,517,581 RGD:1600115 ENSEMBL
G Crk v-crk sarcoma virus CT10 oncogene homolog (avian) GBrowse link IMP 10 63,017,662 63,040,420 RGD:1298801 RGD
G Csta cystatin A (stefin A) GBrowse link ISO 11 66,456,248 66,467,253 RGD:1624291 RGD
G Cux1 cut-like homeobox 1 GBrowse link IPI 12 21,223,919 21,516,938 RGD:1599272 RGD
G Dsp desmoplakin GBrowse link ISO 17 32,848,313 32,896,044 RGD:1624291 RGD
G Dsp desmoplakin GBrowse link IEA 17 32,848,313 32,896,044 RGD:1600115 ENSEMBL
G Evpl envoplakin GBrowse link ISO 10 106,336,953 106,353,217 RGD:1624291 RGD
G Fga fibrinogen alpha chain GBrowse link IEA 2 174,737,640 174,753,598 RGD:1600115 InterPro
G Fgb fibrinogen beta chain GBrowse link IEA 2 174,768,193 174,775,102 RGD:1600115 InterPro
G Fgg fibrinogen gamma chain GBrowse link IEA 2 174,727,312 174,734,594 RGD:1600115 InterPro
G Frmd4a FERM domain containing 4A GBrowse link ISO 17 84,783,244 85,068,101 RGD:1624291 RGD
G Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) IEA RGD:1600115 InterPro
G Fscn2 fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) GBrowse link IEA 10 109,789,092 109,795,631 RGD:1600115 InterPro
G Fscn3 fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus) GBrowse link IEA 4 55,298,103 55,307,523 RGD:1600115 InterPro
G Gatad2a GATA zinc finger domain containing 2A GBrowse link ISO 16 19,913,558 20,004,379 RGD:1624291 RGD
G Gatad2a GATA zinc finger domain containing 2A GBrowse link IEA 16 19,913,558 20,004,379 RGD:1600115 ENSEMBL
G Golga5 golgin A5 GBrowse link IPI 6 126,740,320 126,765,513 RGD:1599272 RGD
G Gphn gephyrin GBrowse link TAS 6 100,833,004 101,302,957 RGD:69377 RGD
G Il1rap interleukin 1 receptor accessory protein GBrowse link TAS 11 76,092,252 76,222,576 RGD:633114 RGD
G Ivl involucrin GBrowse link ISO 2 185,556,271 185,558,310 RGD:1624291 RGD
G Ivl involucrin GBrowse link IEA 2 185,556,271 185,558,310 RGD:1600115 ENSEMBL
G Lor loricrin GBrowse link ISO 2 184,953,538 184,955,283 RGD:1624291 RGD
G Men1 multiple endocrine neoplasia I GBrowse link ISO 1 209,114,987 209,120,837 RGD:1624291 RGD
G Msn moesin GBrowse link TAS X 83,716,068 83,784,214 RGD:1300204 RGD
G Nufip1 nuclear fragile X mental retardation protein interacting protein 1 GBrowse link ISO 15 57,028,109 57,058,834 RGD:1624291 RGD
G Nufip1 nuclear fragile X mental retardation protein interacting protein 1 GBrowse link IEA 15 57,028,109 57,058,834 RGD:1600115 ENSEMBL
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 GBrowse link ISO 4 135,720,581 135,761,507 RGD:1624291 RGD
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit GBrowse link IDA 5 126,007,672 126,074,012 RGD:1600470 RGD
G Rabac1 Rab acceptor 1 (prenylated) GBrowse link NAS 1 80,271,951 80,275,050 RGD:633794 RGD
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link ISO 10 39,112,733 39,164,694 RGD:1624291 RGD
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link IEA 10 39,112,733 39,164,694 RGD:1600115 ENSEMBL
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link ISS 10 39,112,733 39,164,694 RGD:1600115 UniProtKB
G Sprr1a small proline-rich protein 1A GBrowse link ISO 2 185,463,951 185,465,849 RGD:1624291 RGD
G Sprr1b small proline-rich protein 1B GBrowse link ISO 2 185,418,131 185,418,568 RGD:1624291 RGD
G Ssx2ip synovial sarcoma, X breakpoint 2 interacting protein GBrowse link NAS 2 244,604,360 244,637,562 RGD:629551 RGD
G Stx1a syntaxin 1A (brain) GBrowse link IPI 12 22,737,112 22,765,064 RGD:1581734 RGD
G Stx1a syntaxin 1A (brain) GBrowse link IPI 12 22,737,112 22,765,064 RGD:1581734 RGD
G Stx1a syntaxin 1A (brain) GBrowse link IPI 12 22,737,112 22,765,064 RGD:1581734 RGD
G Tagln transgelin GBrowse link TAS 8 48,902,208 48,907,682 RGD:730181 RGD
G Tcap titin-cap ISO RGD:1624291 RGD
G Tchh trichohyalin GBrowse link ISO 2 186,528,154 186,533,876 RGD:1624291 RGD
G Tnnt2 troponin T type 2 (cardiac) GBrowse link IDA 13 48,872,972 48,885,815 RGD:1580456 RGD
G Wwc1 WW and C2 domain containing 1 GBrowse link IPI 10 20,750,770 20,910,298 RGD:5131959 RGD
G Zfp748 zinc finger protein 748 GBrowse link ISO 17 5,298,983 5,318,612 RGD:1624291 RGD
SH3/SH2 adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Blnk B-cell linker GBrowse link ISO 1 246,091,335 246,165,075 RGD:1624291 RGD
G Cd28 Cd28 molecule GBrowse link ISO 9 59,342,273 59,367,743 RGD:1624291 RGD
G Cd28 Cd28 molecule GBrowse link IEA 9 59,342,273 59,367,743 RGD:1600115 ENSEMBL
G Crk v-crk sarcoma virus CT10 oncogene homolog (avian) GBrowse link ISO 10 63,017,662 63,040,420 RGD:1624291 RGD
G Crk v-crk sarcoma virus CT10 oncogene homolog (avian) GBrowse link IEA 10 63,017,662 63,040,420 RGD:1600115 ENSEMBL
G Grb10 growth factor receptor bound protein 10 GBrowse link ISO 14 92,814,797 92,911,442 RGD:1624291 RGD
G Grb10 growth factor receptor bound protein 10 GBrowse link ISO 14 92,814,797 92,911,442 RGD:1624291 RGD
G Grb10 growth factor receptor bound protein 10 GBrowse link IEA 14 92,814,797 92,911,442 RGD:1600115 ENSEMBL
G Grb14 growth factor receptor bound protein 14 GBrowse link ISO 3 46,832,380 46,952,670 RGD:1624291 RGD
G Grb2 growth factor receptor bound protein 2 GBrowse link ISO 10 105,722,014 105,818,649 RGD:1624291 RGD
G Grb2 growth factor receptor bound protein 2 GBrowse link IEA 10 105,722,014 105,818,649 RGD:1600115 ENSEMBL
G Hsh2d hematopoietic SH2 domain containing GBrowse link ISO 16 18,060,515 18,072,470 RGD:1624291 RGD
G Hsh2d hematopoietic SH2 domain containing GBrowse link IEA 16 18,060,515 18,072,470 RGD:1600115 ENSEMBL
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 GBrowse link ISO 5 148,801,685 148,802,351 RGD:1624291 RGD
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 GBrowse link ISO 5 148,801,685 148,802,351 RGD:1624291 RGD
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 GBrowse link IPI 5 148,801,685 148,802,351 RGD:1358238 UniProtKB
G Lat linker for activation of T cells GBrowse link ISO 1 185,450,155 185,455,180 RGD:1624291 RGD
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link IEA 12 36,501,886 36,558,055 RGD:1600115 ENSEMBL
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link ISO 12 36,501,886 36,558,055 RGD:1624291 RGD
G Sh2b2 SH2B adaptor protein 2 GBrowse link ISO 12 21,544,434 21,572,232 RGD:1624291 RGD
G Sh2b2 SH2B adaptor protein 2 GBrowse link ISO 12 21,544,434 21,572,232 RGD:1624291 RGD
G Sh2b2 SH2B adaptor protein 2 GBrowse link IEA 12 21,544,434 21,572,232 RGD:1600115 ENSEMBL
G Sh2d1a SH2 domain containing 1A GBrowse link IEA X 2,532,295 2,560,524 RGD:1600115 InterPro
G Sh2d2a SH2 domain containing 2A GBrowse link TAS 2 179,916,108 179,924,623 RGD:1304009 RGD
G Sla2 Src-like-adaptor 2 GBrowse link IEA 3 147,277,668 147,290,729 RGD:1600115 ENSEMBL
G Sla2 Src-like-adaptor 2 GBrowse link ISO 3 147,277,668 147,290,729 RGD:1624291 RGD
G Sorbs1 sorbin and SH3 domain containing 1 GBrowse link ISO 1 245,419,532 245,527,846 RGD:1624291 RGD
G Stap1 signal transducing adaptor family member 1 GBrowse link ISO 14 23,734,558 23,764,077 RGD:1624291 RGD
G Stap1 signal transducing adaptor family member 1 GBrowse link IEA 14 23,734,558 23,764,077 RGD:1600115 ENSEMBL
signaling adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Dab2ip DAB2 interacting protein GBrowse link ISO 3 14,667,700 14,840,625 RGD:1624291 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cbp Csk binding protein TAS RGD:625637 RGD
G Dok2 docking protein 2 GBrowse link ISO 15 51,171,277 51,174,337 RGD:1624291 RGD
G Dok2 docking protein 2 GBrowse link IEA 15 51,171,277 51,174,337 RGD:1600115 ENSEMBL
G Frs2 fibroblast growth factor receptor substrate 2 GBrowse link ISO 7 56,409,863 56,490,535 RGD:1624291 RGD
G Frs2 fibroblast growth factor receptor substrate 2 GBrowse link IEA 7 56,409,863 56,490,535 RGD:1600115 ENSEMBL
G Gab2 GRB2-associated binding protein 2 GBrowse link ISO 1 154,348,777 154,544,906 RGD:1624291 RGD
G Gab2 GRB2-associated binding protein 2 GBrowse link ISS 1 154,348,777 154,544,906 RGD:1600115 UniProtKB
G Irs1 insulin receptor substrate 1 GBrowse link IMP 9 81,585,251 81,638,071 BHF-UCL
G Sh2b2 SH2B adaptor protein 2 GBrowse link ISO 12 21,544,434 21,572,232 RGD:1624291 RGD
G Sh2b2 SH2B adaptor protein 2 GBrowse link IEA 12 21,544,434 21,572,232 RGD:1600115 ENSEMBL
triplet codon-amino acid adaptor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G mt-Th mitochondrially encoded tRNA histidine GBrowse link TAS MT 11,538 11,605 RGD:631900 RGD
Term paths to the root
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Term Annotations click to browse term
  molecular_function 87625
    binding 56359
      binding, bridging 128
        protein binding, bridging + 109
        signaling adaptor activity + 51
        triplet codon-amino acid adaptor activity + 2
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