ONTOLOGY REPORT - ANNOTATIONS


Term:binding, bridging
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Accession:GO:0060090 term browser browse the term
Definition:The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
Synonyms:exact_synonym: molecular adaptor activity


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binding, bridging term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1600115
RGD:1624291
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1600115
RGD:1624291
G Tradd TNFRSF1A-associated via death domain JBrowse link 19 37,214,461 37,221,099 RGD:1600115
RGD:1624291
CCC codon-amino acid adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G mt-Tp mitochondrially encoded tRNA proline JBrowse link MT 15,348 15,415 RGD:2317000
clathrin adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1601545
G Dab2 DAB2, clathrin adaptor protein JBrowse link 2 55,747,353 55,768,848 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1600115
RGD:1624291
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1600115
RGD:1624291
COPII adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tex261 testis expressed 261 JBrowse link 4 115,446,830 115,454,035 RGD:1600115
cytoskeletal adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank1 ankyrin 1 JBrowse link 16 73,681,422 73,912,605 RGD:1600115
RGD:1624291
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1600115
G Baiap2 BAI1-associated protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:1600115
G Baiap2l1 BAI1-associated protein 2-like 1 JBrowse link 12 12,226,967 12,321,172 RGD:1600115
G Baiap2l2 BAI1-associated protein 2-like 2 JBrowse link 7 120,492,366 120,518,803 RGD:1600115
G Bicd1 BICD cargo adaptor 1 JBrowse link 4 184,018,845 184,167,628 RGD:1600115
RGD:1624291
G Gas2l1 growth arrest-specific 2 like 1 JBrowse link 14 85,308,443 85,318,475 RGD:1600115
RGD:1624291
G Gas2l2 growth arrest-specific 2 like 2 JBrowse link 10 70,639,429 70,646,402 RGD:1600115
RGD:1624291
G LOC108348322 GAS2-like protein 2 RGD:1600115
JAK pathway signal transduction adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1624291
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:1600115
MAP-kinase scaffold activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:1600115
RGD:1624291
RGD:11059588
G Dusp19 dual specificity phosphatase 19 JBrowse link 3 67,849,966 67,862,475 RGD:1624291
G Ksr1 kinase suppressor of ras 1 JBrowse link 10 66,323,704 66,342,469 RGD:1600115
RGD:1624291
G Ksr2 kinase suppressor of ras 2 JBrowse link 12 44,531,376 44,911,835 RGD:1624291
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 3 81,295,023 81,304,181 RGD:1624291
RGD:2298766
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 10 14,259,394 14,299,276 RGD:1600115
RGD:1624291
G Spag9 sperm associated antigen 9 JBrowse link 10 81,693,736 81,827,562 RGD:1600115
protein binding, bridging term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amfr autocrine motility factor receptor JBrowse link 19 11,473,538 11,509,500 RGD:1600115
RGD:1624291
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:8693373
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1600115
RGD:1624291
G Arpc4 actin related protein 2/3 complex, subunit 4 JBrowse link 4 145,330,457 145,340,985 RGD:1600115
RGD:1624291
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:1600115
RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:1600115
RGD:1624291
G Cbx5 chromobox 5 JBrowse link 7 144,819,673 144,865,014 RGD:1600115
RGD:1624291
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 JBrowse link 5 152,447,348 152,458,005 RGD:1600115
RGD:1624291
G Cnn3 calponin 3 JBrowse link 2 225,005,069 225,036,179 RGD:727577
G Cntln centlein JBrowse link 5 103,251,986 103,367,088 RGD:1624291
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 7 36,395,665 36,408,588 RGD:1600115
RGD:1624291
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:1298801
G Cux1 cut-like homeobox 1 JBrowse link 12 23,150,886 23,470,095 RGD:1599272
G Ddx20 DEAD-box helicase 20 JBrowse link 2 208,144,142 208,154,764 RGD:1600115
RGD:1624291
RGD:2290270
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1600115
RGD:1624291
G Dvl2 dishevelled segment polarity protein 2 JBrowse link 10 56,609,810 56,619,269 RGD:1600115
RGD:1624291
G Dvl3 dishevelled segment polarity protein 3 JBrowse link 11 84,051,177 84,068,479 RGD:1600115
RGD:1624291
G Evpl envoplakin JBrowse link 10 105,100,538 105,116,802 RGD:1600115
RGD:1624291
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1600115
RGD:1624291
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:1600115
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:1600115
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:1600115
G Frmd4a FERM domain containing 4A JBrowse link 17 77,642,302 77,918,210 RGD:1600115
RGD:1624291
G Fscn1 fascin actin-bundling protein 1 JBrowse link 12 13,655,459 13,668,595 RGD:1600115
G Fscn2 fascin actin-bundling protein 2, retinal JBrowse link 10 109,528,307 109,540,675 RGD:1600115
G Fscn3 fascin actin-bundling protein 3 JBrowse link 4 55,719,976 55,729,442 RGD:1600115
G Gatad2a GATA zinc finger domain containing 2A JBrowse link 16 21,177,793 21,267,768 RGD:1600115
RGD:1624291
G Golga5 golgin A5 JBrowse link 6 126,350,572 126,378,735 RGD:1599272
G Gphn gephyrin JBrowse link 6 101,327,874 101,859,169 RGD:69377
G Il1rap interleukin 1 receptor accessory protein JBrowse link 11 77,456,648 77,593,208 RGD:633114
G Ivl involucrin JBrowse link 2 192,761,171 192,773,346 RGD:1624291
G LOC100911790 stefin-3-like JBrowse link 11 67,523,815 67,528,953 RGD:1624291
G LOC102549842 zinc finger protein 91-like JBrowse link 1 37,947,138 37,966,046 RGD:1600115
G Lor loricrin JBrowse link 2 191,984,455 191,990,713 RGD:1624291
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:1600115
RGD:1624291
G Msn moesin JBrowse link X 65,226,834 65,294,192 RGD:1300204
G Nefh neurofilament, heavy polypeptide JBrowse link 14 85,181,572 85,191,557 RGD:8554743
G Nefl neurofilament, light polypeptide JBrowse link 15 44,799,378 44,803,251 RGD:1600115
RGD:1624291
G Nmd3 NMD3 ribosome export adaptor JBrowse link 2 166,402,838 166,428,331 RGD:1600115
RGD:1624291
G Nufip1 NUFIP1, FMR1 interacting protein 1 JBrowse link 15 58,171,163 58,201,888 RGD:1600115
RGD:1624291
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:1600115
RGD:1624291
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha JBrowse link 8 109,481,352 109,621,462 RGD:1624291
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 JBrowse link 4 133,285,552 133,323,755 RGD:1600115
RGD:1624291
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:1600470
G Rabac1 Rab acceptor 1 JBrowse link 1 81,843,667 81,846,765 RGD:633794
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1600115
RGD:1624291
G RGD1310769 similar to HSPC288 JBrowse link 6 109,683,252 109,692,218 RGD:1600115
G Rptor regulatory associated protein of MTOR, complex 1 JBrowse link 10 108,750,620 109,058,691 RGD:1600115
RGD:1624291
G Sprr1a small proline-rich protein 1A JBrowse link 2 192,669,143 192,671,059 RGD:1624291
G Ssx2ip SSX family member 2 interacting protein JBrowse link 2 252,263,323 252,296,049 RGD:629551
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:1581734
G Tagln transgelin JBrowse link 8 50,222,895 50,228,369 RGD:730181
G Tcap titin-cap JBrowse link 10 86,337,705 86,338,414 RGD:1624291
G Tchh trichohyalin JBrowse link 2 193,778,022 193,784,793 RGD:1624291
G Tjp2 tight junction protein 2 JBrowse link 1 241,945,816 242,084,044 RGD:1624291
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:1580456
G Trim17 tripartite motif-containing 17 JBrowse link 10 45,307,007 45,314,823 RGD:1600115
RGD:1624291
G Trim5 tripartite motif-containing 5 JBrowse link 1 169,446,774 169,463,760 RGD:1624291
G Trim6 tripartite motif containing 6 JBrowse link 1 169,410,084 169,423,305 RGD:1600115
RGD:1624291
G Vps11 VPS11 CORVET/HOPS core subunit JBrowse link 8 48,677,492 48,692,295 RGD:1600115
G Vps18 VPS18 CORVET/HOPS core subunit JBrowse link 3 111,097,352 111,108,206 RGD:1600115
G Wwc1 WW and C2 domain containing 1 JBrowse link 10 20,662,996 20,818,500 RGD:5131959
SH3/SH2 adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blnk B-cell linker JBrowse link 1 260,187,023 260,254,490 RGD:1600115
RGD:1624291
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1600115
RGD:1624291
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:1600115
RGD:1624291
G Fcrl2 Fc receptor-like 2 JBrowse link 2 186,594,442 186,605,115 RGD:1624291
G Grb10 growth factor receptor bound protein 10 JBrowse link 14 92,021,851 92,122,249 RGD:1600115
RGD:1624291
G Grb14 growth factor receptor bound protein 14 JBrowse link 3 50,937,403 51,054,447 RGD:1600115
RGD:1624291
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:1600115
RGD:1624291
G Hsh2d hematopoietic SH2 domain containing JBrowse link 16 19,336,400 19,349,868 RGD:1600115
RGD:1624291
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 JBrowse link 5 147,927,145 147,953,093 RGD:1358238
RGD:1624291
G Lat linker for activation of T cells JBrowse link 1 197,765,644 197,770,669 RGD:1600115
RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1600115
RGD:1624291
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1600115
RGD:1624291
G Sh2d1a SH2 domain containing 1A JBrowse link X 128,897,053 128,925,408 RGD:1600115
G Sh2d2a SH2 domain containing 2A JBrowse link 2 187,218,851 187,225,000 RGD:1304009
G Skap1 src kinase associated phosphoprotein 1 JBrowse link 10 84,309,379 84,619,051 RGD:1600115
G Skap2 src kinase associated phosphoprotein 2 JBrowse link 4 81,816,778 81,968,832 RGD:1600115
G Sla2 Src-like-adaptor 2 JBrowse link 3 152,942,838 153,004,047 RGD:1600115
RGD:1624291
G Sorbs1 sorbin and SH3 domain containing 1 JBrowse link 1 259,373,921 259,502,108 RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1600115
RGD:1624291
signaling adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afap1l2 actin filament associated protein 1-like 2 JBrowse link 1 277,730,760 277,827,299 RGD:1600115
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Eps8 epidermal growth factor receptor pathway substrate 8 JBrowse link 4 171,475,155 171,645,620 RGD:1600115
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1600115
RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1624291
G Sh2b1 SH2B adaptor protein 1 JBrowse link 1 197,878,839 197,888,223 RGD:1600115
G Sh2b3 SH2B adaptor protein 3 JBrowse link 12 40,261,990 40,265,757 RGD:1600115
transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blnk B-cell linker JBrowse link 1 260,187,023 260,254,490 RGD:1600115
G Dok2 docking protein 2 JBrowse link 15 52,449,884 52,455,414 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:1600115
RGD:1624291
G Gab2 GRB2-associated binding protein 2 JBrowse link 1 162,082,876 162,283,379 RGD:1600115
RGD:1624291
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8553881
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 JBrowse link 2 94,266,104 94,277,680 RGD:625637
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1600115
RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1600115
RGD:1624291
triplet codon-amino acid adaptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G mt-Th mitochondrially encoded tRNA histidine JBrowse link MT 11,538 11,605 RGD:631900

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  molecular_function 394180
    binding 256653
      binding, bridging 556
        protein binding, bridging + 471
        signaling adaptor activity + 228
        triplet codon-amino acid adaptor activity + 10
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