ONTOLOGY REPORT - ANNOTATIONS


Term:binding, bridging
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Accession:GO:0060090 term browser browse the term
Definition:The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
Synonyms:exact_synonym: molecular adaptor activity


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binding, bridging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Gas6 growth arrest specific 6 GBrowse link 16 80,701,559 80,732,410 RGD:1600115
RGD:1624291
G Pdcd6 programmed cell death 6 GBrowse link 1 33,002,331 33,017,997 RGD:1600115
RGD:1624291
G Tradd TNFRSF1A-associated via death domain GBrowse link 19 48,081,076 48,086,774 RGD:1600115
RGD:1624291
CCC codon-amino acid adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G mt-Tp mitochondrially encoded tRNA proline GBrowse link MT 15,348 15,415 RGD:2317000
clathrin adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 GBrowse link 1 170,705,795 170,777,617 RGD:1601545
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link 2 75,489,435 75,510,930 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link 5 156,742,863 156,765,855 RGD:1600115
RGD:1624291
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link 1 160,681,689 160,763,382 RGD:1600115
RGD:1624291
cytoskeletal adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ank1 ankyrin 1, erythrocytic GBrowse link 16
16
73,397,821
73,314,002
73,459,822
73,331,197
RGD:1624291
G Arhgap26 Rho GTPase activating protein 26 GBrowse link 18 31,484,480 31,890,142 RGD:1600115
G Baiap2 BAI1-associated protein 2 GBrowse link 10 108,707,257 108,785,617 RGD:1600115
G Baiap2l1 BAI1-associated protein 2-like 1 GBrowse link 12 14,285,428 14,373,560 RGD:1600115
G Baiap2l2 BAI1-associated protein 2-like 2 GBrowse link 7 120,486,012 120,511,945 RGD:1600115
G Bicd1 bicaudal D homolog 1 (Drosophila) GBrowse link 4 248,136,721 248,287,045 RGD:1600115
RGD:1624291
G Gas2l1 growth arrest-specific 2 like 1 GBrowse link 14 85,986,064 85,995,860 RGD:1624291
G Gas2l2 growth arrest-specific 2 like 2 GBrowse link 10 71,101,453 71,108,426 RGD:1600115
G LOC100912215 GAS2-like protein 2-like GBrowse link 10 70,272,234 70,280,616 RGD:1624291
G Mtss1 metastasis suppressor 1 GBrowse link 7 99,419,324 99,558,069 RGD:1600115
G Mtss1l metastasis suppressor 1-like GBrowse link 19 51,730,106 51,745,921 RGD:1600115
JAK pathway signal transduction adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Sh2b2 SH2B adaptor protein 2 GBrowse link 12 25,472,225 25,501,387 RGD:1600115
RGD:1624291
G Socs2 suppressor of cytokine signaling 2 GBrowse link 7 36,558,014 36,560,623 RGD:1600115
MAP-kinase scaffold activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dusp19 dual specificity phosphatase 19 GBrowse link 3 74,406,311 74,418,820 RGD:1624291
G Ksr1 kinase suppressor of ras 1 GBrowse link 10 65,166,705 65,302,975 RGD:1600115
RGD:1624291
G Ksr2 kinase suppressor of ras 2 GBrowse link 12 46,352,196 46,732,484 RGD:1624291
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 GBrowse link 3 87,998,491 88,016,191 RGD:1624291
RGD:2298766
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 GBrowse link 10 14,075,410 14,115,275 RGD:1600115
RGD:1624291
protein binding, bridging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ank2 ankyrin 2, neuronal GBrowse link 2 250,573,979 250,869,144 RGD:1600115
RGD:1624291
G Ank3 ankyrin 3, node of Ranvier (ankyrin G) GBrowse link 20 22,087,201 22,609,939 RGD:8693373
G Anxa1 annexin A1 GBrowse link 1 245,192,875 245,220,057 RGD:1600115
RGD:1624291
G Arpc4 actin related protein 2/3 complex, subunit 4 GBrowse link 4 208,627,502 208,638,030 RGD:1600115
RGD:1624291
G Cbx5 chromobox homolog 5 GBrowse link 7 142,605,275 142,647,738 RGD:1600115
RGD:1624291
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 GBrowse link 5 156,206,363 156,217,020 RGD:1600115
RGD:1624291
G Cnn3 calponin 3, acidic GBrowse link 2 243,044,080 243,075,234 RGD:727577
G Cntln centlein, centrosomal protein GBrowse link 5 107,173,114 107,366,594 RGD:1624291
G Col1a2 collagen, type I, alpha 2 GBrowse link 4
4
29,442,828
31,405,253
29,478,616
31,440,180
RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link 7 36,457,911 36,470,834 RGD:1600115
RGD:1624291
G Crk v-crk avian sarcoma virus CT10 oncogene homolog GBrowse link 10 64,149,243 64,175,511 RGD:1298801
G Cux1 cut-like homeobox 1 GBrowse link 12 25,151,301 25,470,445 RGD:1599272
G Dsp desmoplakin GBrowse link 17 29,201,872 29,249,490 RGD:1600115
RGD:1624291
G Evpl envoplakin GBrowse link 10 104,768,140 104,784,797 RGD:1624291
G Fbxw7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase GBrowse link 2 203,633,724 203,708,120 RGD:1624291
G Fga fibrinogen alpha chain GBrowse link 2 201,412,182 201,428,346 RGD:1600115
G Fgb fibrinogen beta chain GBrowse link 2 201,442,664 201,449,657 RGD:1600115
G Fgg fibrinogen gamma chain GBrowse link 2 201,401,700 201,409,143 RGD:1600115
G Frmd4a FERM domain containing 4A GBrowse link 17 79,297,096 79,568,891 RGD:1600115
RGD:1624291
G Fscn1 fascin actin-bundling protein 1 GBrowse link 12 15,688,989 15,702,125 RGD:1600115
G Fscn2 fascin actin-bundling protein 2, retinal GBrowse link 10 109,128,055 109,134,594 RGD:1600115
G Fscn3 fascin actin-bundling protein 3, testicular GBrowse link 4 55,467,449 55,476,891 RGD:1600115
G Gatad2a GATA zinc finger domain containing 2A GBrowse link 16 21,093,916 21,184,843 RGD:1600115
RGD:1624291
G Golga5 golgin A5 GBrowse link 6 135,561,133 135,589,807 RGD:1599272
G Gphn gephyrin GBrowse link 6
6
110,709,516
111,210,069
111,190,440
111,237,661
RGD:69377
G Il1rap interleukin 1 receptor accessory protein GBrowse link 11 83,123,891 83,260,450 RGD:633114
G Ivl involucrin GBrowse link 2 212,096,984 212,109,138 RGD:1600115
RGD:1624291
G LOC100911790 stefin-3-like GBrowse link 11 70,611,292 70,616,430 RGD:1624291
G Men1 multiple endocrine neoplasia I GBrowse link 1 228,692,520 228,698,433 RGD:1600115
RGD:1624291
G Msn moesin GBrowse link X 66,068,480 66,135,838 RGD:1300204
G Nefh neurofilament, heavy polypeptide GBrowse link 14 85,859,193 85,869,187 RGD:8554743
G Nefl neurofilament, light polypeptide GBrowse link 15 46,793,526 46,797,399 RGD:1600115
RGD:1624291
G Nmd3 NMD3 ribosome export adaptor GBrowse link 2 185,759,080 185,784,444 RGD:1600115
RGD:1624291
G Nufip1 nuclear fragile X mental retardation protein interacting protein 1 GBrowse link 15 61,872,647 61,903,369 RGD:1600115
RGD:1624291
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 GBrowse link 4 197,767,067 197,805,270 RGD:1600115
RGD:1624291
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit GBrowse link 5 128,436,023 128,503,874 RGD:1600470
G Rabac1 Rab acceptor 1 (prenylated) GBrowse link 1 83,095,963 83,099,061 RGD:633794
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link 10 38,783,860 38,835,810 RGD:1600115
RGD:1624291
G Sprr1a small proline-rich protein 1A GBrowse link 2 212,199,250 212,201,166 RGD:1624291
G Ssx2ip synovial sarcoma, X breakpoint 2 interacting protein GBrowse link 2 270,790,310 270,823,013 RGD:629551
G Stx1a syntaxin 1A (brain) GBrowse link 12 26,682,320 26,710,272 RGD:1581734
G Tagln transgelin GBrowse link 8 48,847,354 48,853,081 RGD:730181
G Tcap titin-cap RGD:1624291
G Tnnt2 troponin T type 2 (cardiac) GBrowse link 13 57,711,369 57,729,182 RGD:1580456
G Wwc1 WW and C2 domain containing 1 GBrowse link 10 20,535,256 20,689,364 RGD:5131959
SH3/SH2 adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Blnk B-cell linker GBrowse link 1 267,630,219 267,697,917 RGD:1624291
G Cd28 Cd28 molecule GBrowse link 9 67,358,994 67,386,424 RGD:1600115
RGD:1624291
G Crk v-crk avian sarcoma virus CT10 oncogene homolog GBrowse link 10 64,149,243 64,175,511 RGD:1600115
RGD:1624291
G Fcrl2 Fc receptor-like 2 GBrowse link 2 205,998,855 206,009,528 RGD:1600115
RGD:1624291
G Grb10 growth factor receptor bound protein 10 GBrowse link 14 91,818,383 91,914,937 RGD:1600115
RGD:1624291
G Grb14 growth factor receptor bound protein 14 GBrowse link 3
3
57,679,758
57,578,226
57,695,025
57,619,404
RGD:1600115
RGD:1624291
G Grb2 growth factor receptor bound protein 2 GBrowse link 10
10
104,019,823
104,735,560
104,087,251
104,738,091
RGD:1600115
RGD:1624291
G Hsh2d hematopoietic SH2 domain containing GBrowse link 16 19,194,746 19,207,770 RGD:1600115
RGD:1624291
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 GBrowse link 5 151,655,530 151,680,547 RGD:1358238
RGD:1624291
G Lat linker for activation of T cells GBrowse link 1 204,747,718 204,752,745 RGD:1600115
RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 42,762,630 42,822,760 RGD:1600115
RGD:1624291
G Sh2b2 SH2B adaptor protein 2 GBrowse link 12 25,472,225 25,501,387 RGD:1600115
RGD:1624291
G Sh2d1a SH2 domain containing 1A GBrowse link X 128,978,818 129,007,045 RGD:1600115
G Sh2d2a SH2 domain containing 2A GBrowse link 2 206,622,869 206,629,299 RGD:1304009
G Sla2 Src-like-adaptor 2 GBrowse link 3 158,742,486 158,752,778 RGD:1600115
RGD:1624291
G Sorbs1 sorbin and SH3 domain containing 1 GBrowse link 1 266,817,755 267,037,940 RGD:1624291
G Stap1 signal transducing adaptor family member 1 GBrowse link 14 23,479,674 23,508,287 RGD:1600115
RGD:1624291
signaling adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dab2ip DAB2 interacting protein GBrowse link 3 20,200,937 20,371,268 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link 5 156,742,863 156,765,855 RGD:1600115
RGD:1624291
transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dok2 docking protein 2 GBrowse link 15 56,165,853 56,179,111 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 GBrowse link 7 60,128,589 60,210,278 RGD:1600115
RGD:1624291
G Gab2 GRB2-associated binding protein 2 GBrowse link 1 168,423,264 168,486,051 RGD:1600115
RGD:1624291
G Irs1 insulin receptor substrate 1 GBrowse link 9 87,782,499 87,835,248 RGD:8553881
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 GBrowse link 2 114,018,219 114,030,544 RGD:625637
G Sh2b2 SH2B adaptor protein 2 GBrowse link 12 25,472,225 25,501,387 RGD:1600115
RGD:1624291
triplet codon-amino acid adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G mt-Th mitochondrially encoded tRNA histidine GBrowse link MT 11,538 11,605 RGD:631900

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Term Annotations click to browse term
  molecular_function 315109
    binding 194926
      binding, bridging 430
        protein binding, bridging + 374
        signaling adaptor activity + 179
        triplet codon-amino acid adaptor activity + 10
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