ONTOLOGY REPORT - ANNOTATIONS


Term:binding, bridging
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Accession:GO:0060090 term browser browse the term
Definition:The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
Synonyms:exact_synonym: molecular adaptor activity


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binding, bridging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Gas6 growth arrest specific 6 GBrowse link 16 80,900,159 80,930,929 RGD:1600115
RGD:1624291
G Pdcd6 programmed cell death 6 GBrowse link 1 29,769,911 29,785,577 RGD:1600115
RGD:1624291
G Tradd TNFRSF1A-associated via death domain GBrowse link 19 35,073,150 35,075,251 RGD:1600115
RGD:1624291
CCC codon-amino acid adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G mt-Tp mitochondrially encoded tRNA proline GBrowse link MT 15,348 15,415 RGD:2317000
clathrin adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 GBrowse link 1 156,871,564 156,937,540 RGD:1601545
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link 2 55,714,874 55,736,370 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link 5 153,504,535 153,527,523 RGD:1600115
RGD:1624291
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link 1 146,754,085 146,834,197 RGD:1600115
RGD:1624291
cytoskeletal adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ank1 ankyrin 1, erythrocytic GBrowse link 16 73,333,564 73,437,926 RGD:1624291
G Arhgap26 Rho GTPase activating protein 26 GBrowse link 18 31,934,753 32,327,551 RGD:1600115
G Baiap2 BAI1-associated protein 2 GBrowse link 10 109,351,201 109,413,703 RGD:1600115
G Baiap2l1 BAI1-associated protein 2-like 1 GBrowse link 12 10,584,749 10,668,948 RGD:1600115
G Baiap2l2 BAI1-associated protein 2-like 2 GBrowse link 7 117,240,190 117,265,958 RGD:1600115
G Bicd1 bicaudal D homolog 1 (Drosophila) GBrowse link 4 186,922,060 187,069,288 RGD:1600115
RGD:1624291
G Gas2l1 growth arrest-specific 2 like 1 GBrowse link 14 85,716,617 85,726,368 RGD:1600115
RGD:1624291
G Gas2l2 growth arrest-specific 2 like 2 GBrowse link 10 71,505,385 71,512,429 RGD:1600115
RGD:1624291
G Mtss1 metastasis suppressor 1 GBrowse link 7 95,808,266 95,947,927 RGD:1600115
G Mtss1l metastasis suppressor 1-like GBrowse link 19 40,640,947 40,661,240 RGD:1600115
JAK pathway signal transduction adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Sh2b2 SH2B adaptor protein 2 GBrowse link 12 21,544,434 21,572,232 RGD:1624291
G Socs2 suppressor of cytokine signaling 2 GBrowse link 7 32,605,714 32,608,323 RGD:1600115
MAP-kinase scaffold activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dusp19 dual specificity phosphatase 19 GBrowse link 3 63,473,333 63,485,843 RGD:1624291
G Ksr1 kinase suppressor of ras 1 GBrowse link 10 65,186,444 65,322,155 RGD:1600115
RGD:1624291
G Ksr2 kinase suppressor of ras 2 GBrowse link 12 39,998,030 40,376,125 RGD:1624291
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 GBrowse link 3 76,781,504 76,790,661 RGD:1624291
RGD:2298766
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 GBrowse link 10 14,147,895 14,186,277 RGD:1600115
RGD:1624291
protein binding, bridging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ank2 ankyrin 2, neuronal GBrowse link 2 224,182,431 224,501,751 RGD:1600115
RGD:1624291
G Ank3 ankyrin 3, node of Ranvier (ankyrin G) GBrowse link 20 19,328,684 19,828,196 RGD:8693373
G Anxa1 annexin A1 GBrowse link 1 223,478,436 223,494,455 RGD:1600115
RGD:1624291
G Arpc4 actin related protein 2/3 complex, subunit 4 GBrowse link 4 149,259,767 149,271,500 RGD:1600115
RGD:1624291
G Cbx5 chromobox homolog 5 GBrowse link 7 142,107,922 142,125,543 RGD:1600115
RGD:1624291
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 GBrowse link 5 152,972,551 152,983,208 RGD:1600115
RGD:1624291
G Cnn3 calponin 3, acidic GBrowse link 2 218,044,803 218,075,914 RGD:727577
G Cntln centlein, centrosomal protein GBrowse link 5 103,942,784 104,049,783 RGD:1624291
G Col1a2 collagen, type I, alpha 2 GBrowse link 4 29,393,645 29,428,572 RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link 7 32,504,279 32,517,581 RGD:1600115
RGD:1624291
G Crk v-crk avian sarcoma virus CT10 oncogene homolog GBrowse link 10 63,017,662 63,040,420 RGD:1298801
G Csta cystatin A (stefin A) GBrowse link 11 66,456,248 66,467,253 RGD:1624291
G Cux1 cut-like homeobox 1 GBrowse link 12 21,223,919 21,516,938 RGD:1599272
G Dsp desmoplakin GBrowse link 17 32,848,313 32,896,044 RGD:1600115
RGD:1624291
G Evpl envoplakin GBrowse link 10 106,336,953 106,353,217 RGD:1624291
G Fga fibrinogen alpha chain GBrowse link 2 174,737,640 174,753,598 RGD:1600115
G Fgb fibrinogen beta chain GBrowse link 2 174,768,193 174,775,102 RGD:1600115
G Fgg fibrinogen gamma chain GBrowse link 2 174,727,312 174,734,594 RGD:1600115
G Frmd4a FERM domain containing 4A GBrowse link 17 84,783,244 85,068,101 RGD:1600115
RGD:1624291
G Fscn1 fascin actin-bundling protein 1 RGD:1600115
G Fscn2 fascin actin-bundling protein 2, retinal GBrowse link 10 109,789,092 109,795,631 RGD:1600115
G Fscn3 fascin actin-bundling protein 3, testicular GBrowse link 4 55,298,103 55,307,523 RGD:1600115
G Gatad2a GATA zinc finger domain containing 2A GBrowse link 16 19,913,558 20,004,379 RGD:1600115
RGD:1624291
G Golga5 golgin A5 GBrowse link 6 126,740,320 126,765,513 RGD:1599272
G Gphn gephyrin GBrowse link 6 100,833,004 101,302,957 RGD:69377
G Il1rap interleukin 1 receptor accessory protein GBrowse link 11 76,092,252 76,222,576 RGD:633114
G Ivl involucrin GBrowse link 2 185,556,271 185,558,310 RGD:1600115
RGD:1624291
G LOC501406 similar to regulator of sex-limitation candidate 1 RGD:1600115
G Lor loricrin GBrowse link 2 184,953,538 184,955,283 RGD:1624291
G Men1 multiple endocrine neoplasia I GBrowse link 1 209,114,987 209,120,837 RGD:1600115
RGD:1624291
G Msn moesin GBrowse link X 83,716,068 83,784,214 RGD:1300204
G Nefh neurofilament, heavy polypeptide GBrowse link 14 85,594,789 85,604,774 RGD:8554743
G Nefl neurofilament, light polypeptide GBrowse link 15 47,636,303 47,640,176 RGD:1624291
G Nmd3 NMD3 ribosome export adaptor GBrowse link 2 159,851,267 159,876,465 RGD:1624291
G Nufip1 nuclear fragile X mental retardation protein interacting protein 1 GBrowse link 15 57,028,109 57,058,834 RGD:1600115
RGD:1624291
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 GBrowse link 4 135,720,581 135,761,507 RGD:1600115
RGD:1624291
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit GBrowse link 5 126,007,672 126,074,012 RGD:1600470
G Rabac1 Rab acceptor 1 (prenylated) GBrowse link 1 80,271,951 80,275,050 RGD:633794
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link 10 39,112,733 39,164,694 RGD:1600115
RGD:1624291
G Sprr1a small proline-rich protein 1A GBrowse link 2 185,463,951 185,465,849 RGD:1624291
G Ssx2ip synovial sarcoma, X breakpoint 2 interacting protein GBrowse link 2 244,604,360 244,637,562 RGD:629551
G Stx1a syntaxin 1A (brain) GBrowse link 12 22,737,112 22,765,064 RGD:1581734
G Tagln transgelin GBrowse link 8 48,902,208 48,907,682 RGD:730181
G Tcap titin-cap RGD:1624291
G Tchh trichohyalin GBrowse link 2 186,528,154 186,533,876 RGD:1624291
G Tnnt2 troponin T type 2 (cardiac) GBrowse link 13 48,872,972 48,885,815 RGD:1580456
G Wwc1 WW and C2 domain containing 1 GBrowse link 10 20,750,770 20,910,298 RGD:5131959
SH3/SH2 adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Blnk B-cell linker GBrowse link 1 246,091,335 246,165,075 RGD:1624291
G Cd28 Cd28 molecule GBrowse link 9 59,342,273 59,367,743 RGD:1600115
RGD:1624291
G Crk v-crk avian sarcoma virus CT10 oncogene homolog GBrowse link 10 63,017,662 63,040,420 RGD:1600115
RGD:1624291
G Fcrl2 Fc receptor-like 2 GBrowse link 2 179,283,609 179,294,282 RGD:1600115
RGD:1624291
G Grb10 growth factor receptor bound protein 10 GBrowse link 14 92,814,797 92,911,442 RGD:1600115
RGD:1624291
G Grb14 growth factor receptor bound protein 14 GBrowse link 3 46,832,380 46,952,670 RGD:1600115
RGD:1624291
G Grb2 growth factor receptor bound protein 2 GBrowse link 10 105,722,014 105,818,649 RGD:1600115
RGD:1624291
G Hsh2d hematopoietic SH2 domain containing GBrowse link 16 18,060,515 18,072,470 RGD:1600115
RGD:1624291
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 GBrowse link 5 148,801,685 148,802,351 RGD:1358238
RGD:1624291
G Lat linker for activation of T cells GBrowse link 1 185,450,155 185,455,180 RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 36,501,886 36,558,055 RGD:1600115
RGD:1624291
G Sh2b2 SH2B adaptor protein 2 GBrowse link 12 21,544,434 21,572,232 RGD:1600115
RGD:1624291
G Sh2d1a SH2 domain containing 1A GBrowse link X 2,532,295 2,560,524 RGD:1600115
G Sh2d2a SH2 domain containing 2A GBrowse link 2 179,916,108 179,924,623 RGD:1304009
G Sla2 Src-like-adaptor 2 GBrowse link 3 147,277,668 147,290,729 RGD:1600115
RGD:1624291
G Sorbs1 sorbin and SH3 domain containing 1 GBrowse link 1 245,419,532 245,527,846 RGD:1624291
G Stap1 signal transducing adaptor family member 1 GBrowse link 14 23,734,558 23,764,077 RGD:1600115
RGD:1624291
signaling adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dab2ip DAB2 interacting protein GBrowse link 3 14,667,700 14,840,625 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link 5 153,504,535 153,527,523 RGD:1600115
RGD:1624291
transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dok2 docking protein 2 GBrowse link 15 51,171,277 51,174,337 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 GBrowse link 7 56,409,863 56,490,535 RGD:1600115
RGD:1624291
G Gab2 GRB2-associated binding protein 2 GBrowse link 1 154,348,777 154,544,906 RGD:1600115
RGD:1624291
G Irs1 insulin receptor substrate 1 GBrowse link 9 81,585,251 81,638,071 RGD:8553881
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 RGD:625637
G Sh2b2 SH2B adaptor protein 2 GBrowse link 12 21,544,434 21,572,232 RGD:1600115
RGD:1624291
triplet codon-amino acid adaptor activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G mt-Th mitochondrially encoded tRNA histidine GBrowse link MT 11,538 11,605 RGD:631900

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  molecular_function 108769
    binding 74640
      binding, bridging 153
        protein binding, bridging + 132
        signaling adaptor activity + 57
        triplet codon-amino acid adaptor activity + 2
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