Gene: Shank2 (SH3 and multiple ankyrin repeat domains 2)  Rattus norvegicus

Symbol: Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Description: ENCODES a protein that exhibits protein C-terminus binding; SH3 domain binding; ionotropic glutamate receptor binding (ortholog); INVOLVED IN brain development; response to nutrient; PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH Autistic Disorder (ortholog); FOUND IN brush border membrane; cilium membrane; growth cone; INTERACTS WITH ammonium chloride; cisplatin; nitroglycerin
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cortactin-binding protein 1; CortBP1; GKAP/SAPAP-interacting protein; proline rich synapse associated protein 1; proline-rich synapse-associated protein 1; ProSAP1; SH3 and multiple ankyrin repeat domains 2; SH3 and multiple ankyrin repeat domains protein 2; SH3/ankyrin domain gene 2; Spank-3
Orthologs: Homo sapiens : SHANK2 (SH3 and multiple ankyrin repeat domains 2)  HGNC
Mus musculus : Shank2 (SH3/ankyrin domain gene 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map1q41 NCBI
RGSC Genome Assembly v5.01224,028,791 - 224,449,190+NCBI
RGSC Genome Assembly v5.01222,118,562 - 222,145,426+NCBI
RGSC Genome Assembly v3.41204,399,856 - 204,855,474+NCBI
Rat Celera Assembly1196,732,183 - 197,149,084+NCBI
Genome Assembly 3.11204,553,308 - 205,005,561+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Shank2
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RGD Object Information
RGD ID: 628772
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE