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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Experimental Arthritis
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Accession:DOID:9002457 term browser browse the term
Definition:ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.
Synonyms:exact_synonym: Adjuvant Arthritis;   Arthritis, Adjuvant-Induced;   Collagen Arthritides;   Collagen Arthritis;   Collagen-Induced Arthritides;   Collagen-Induced Arthritis
 primary_id: MESH:D001169
 xref: EFO:1001787

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Experimental Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:intestinal mucosa (rat)
mRNA:altered expression:liver		 CTD
RGD		 PMID:17827786 PMID:19152228 RGD:11040994 RGD:2315573 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 ISO mRNA:decreased expression:kidney RGD PMID:22974786 RGD:11038789 NCBI chrNW_004936501:3,469,928...3,508,577 JBrowse link
G Acan aggrecan treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chrNW_004936483:14,811,152...14,846,305
Ensembl chrNW_004936483:14,811,152...14,846,305 		JBrowse link
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18988084 NCBI chrNW_004936554:4,425,518...4,484,853
Ensembl chrNW_004936554:4,425,495...4,484,887 		JBrowse link
G Acsl4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18988084 NCBI chrNW_004936499:5,456,985...5,540,115
Ensembl chrNW_004936499:5,456,986...5,540,144 		JBrowse link
G Acsl5 acyl-CoA synthetase long chain family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18988084 NCBI chrNW_004936486:2,952,379...2,992,148
Ensembl chrNW_004936486:2,967,522...2,991,154 		JBrowse link
G Adam10 ADAM metallopeptidase domain 10 ISO RGD PMID:23897050 RGD:13703039 NCBI chrNW_004936471:19,760,709...19,911,759
Ensembl chrNW_004936471:19,758,118...19,911,759 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 ISO RGD PMID:23897050 RGD:13703039 NCBI chrNW_004936532:5,864,851...5,904,005
Ensembl chrNW_004936532:5,864,867...5,904,003 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 RGD
CTD		 PMID:19026984 PMID:21681567 PMID:23326410 RGD:5685385 RGD:5686814 NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928 		JBrowse link
G Adk adenosine kinase ISO RGD PMID:11160636 RGD:6482663 NCBI chrNW_004936521:4,560,078...5,023,780
Ensembl chrNW_004936521:4,557,971...5,023,800 		JBrowse link
G Ahcy adenosylhomocysteinase ISO RGD PMID:11123369 RGD:1598898 NCBI chrNW_004936561:6,314,797...6,333,961
Ensembl chrNW_004936561:6,314,705...6,334,439 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194622 NCBI chrNW_004936546:3,737,908...3,783,492
Ensembl chrNW_004936546:3,737,851...3,783,588 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:22391142 RGD:10041007 NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:19675173 RGD:5509599 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253 		JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:10403283 PMID:23267026 RGD:2306928 RGD:7421573 NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413 		JBrowse link
G Anxa2 annexin A2 ameliorates ISO RGD PMID:24819400 RGD:150519886 NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503 		JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood serum (rat) RGD PMID:10892728 RGD:5685694 NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127 		JBrowse link
G Arrb1 arrestin beta 1 ISO protein:increased expression:knee, synoviocyte (rat) RGD PMID:20965243 RGD:5509895 NCBI chrNW_004936498:4,089,621...4,172,749
Ensembl chrNW_004936498:4,094,893...4,172,755 		JBrowse link
G Arrb2 arrestin beta 2 ISO protein:increased expression:knee, synoviocyte (rat) RGD PMID:20965243 RGD:5509895 NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:17408934 RGD:5144054 NCBI chrNW_004936586:1,782,581...1,809,458
Ensembl chrNW_004936586:1,782,528...1,810,010 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:21199477 PMID:22978269 RGD:10054249 RGD:10054498 NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:21199477 PMID:22978269 RGD:10054249 RGD:10054498 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:15001555 RGD:1625760 NCBI chrNW_004936604:551,774...567,014 JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO protein:decreased expression:serum RGD PMID:21406003 RGD:6483549 NCBI chrNW_004936580:5,480,023...5,482,288
Ensembl chrNW_004936580:5,481,355...5,482,155 		JBrowse link
G Btk Bruton tyrosine kinase treatment ISO RGD PMID:22228807 PMID:32083858 RGD:11040701 RGD:151665122 NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441 		JBrowse link
G C3 complement C3 treatment ISO RGD PMID:7347767 PMID:20051658 RGD:11041098 RGD:7411688 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C5 complement C5 ISO RGD PMID:12355496 PMID:20975959 RGD:1600637 RGD:5130175 NCBI chrNW_004936487:9,391,774...9,474,168
Ensembl chrNW_004936487:9,391,804...9,474,159 		JBrowse link
G Cabin1 calcineurin binding protein 1 ISO RGD PMID:22275266 RGD:10054391 NCBI chrNW_004936619:890,474...1,030,914
Ensembl chrNW_004936619:890,299...1,030,899 		JBrowse link
G Calca calcitonin related polypeptide alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16690336 NCBI chrNW_004936528:3,800,801...3,806,000
Ensembl chrNW_004936528:3,800,577...3,805,004 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422 		JBrowse link
G Cbl Cbl proto-oncogene treatment ISO RGD PMID:16984225 RGD:2306289 NCBI chrNW_004936542:4,136,389...4,235,746
Ensembl chrNW_004936542:4,136,511...4,228,288 		JBrowse link
G Cblb Cbl proto-oncogene B ISO RGD PMID:16984225 RGD:2306289 NCBI chrNW_004936701:1,157,790...1,353,375
Ensembl chrNW_004936701:1,157,797...1,353,388 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:synovium, monocytes RGD PMID:9637726 PMID:17052673 RGD:2307143 RGD:4889940 NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965 		JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:27653023 RGD:150429754 NCBI chrNW_004936608:152,174...155,123
Ensembl chrNW_004936608:151,838...155,358 		JBrowse link
G Cd28 CD28 molecule ISO RGD PMID:18601859 RGD:2307202 NCBI chrNW_004936631:335,411...363,407
Ensembl chrNW_004936631:335,411...363,407 		JBrowse link
G Cd4 CD4 molecule treatment ISO RGD PMID:12010568 PMID:15479897 RGD:10058957 RGD:10058960 NCBI chrNW_004936709:997,776...1,022,791
Ensembl chrNW_004936709:997,750...1,022,884 		JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:20435931 RGD:5490544 NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280 		JBrowse link
G Cd40lg CD40 ligand treatment ISO protein:increased expression:plasma (rat) RGD PMID:7689748 PMID:22611405 PMID:27218142 RGD:11344958 RGD:11352298 RGD:11352696 NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403 		JBrowse link
G Cd44 CD44 molecule (IN blood group) ISO protein:increased expression:joint, macrophage, lymphocyte RGD PMID:8639178 RGD:2289388 NCBI chrNW_004936533:2,949,026...3,033,166 JBrowse link
G Cd46 CD46 molecule ISO RGD PMID:21852528 RGD:6483461 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) ISO RGD PMID:14519760 RGD:1600483 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G Cd80 CD80 molecule ISO RGD PMID:22004797 RGD:6902903 NCBI chrNW_004936536:6,462,080...6,483,450 JBrowse link
G Cdc42 cell division cycle 42 ISO protein:increased activation:bone marrow, macrophage RGD PMID:21266780 RGD:5688271 NCBI chrNW_004936474:7,556,765...7,598,687 JBrowse link
G Col2a1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16200597 PMID:21188452 PMID:23326410 PMID:24709313 PMID:25194622 More... NCBI chrNW_004936512:5,861,933...5,894,898
Ensembl chrNW_004936512:5,861,933...5,892,853 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:19205849 PMID:19330884 RGD:2314686 NCBI chrNW_004936519:6,431,156...6,473,183
Ensembl chrNW_004936519:6,431,144...6,481,858 		JBrowse link
G Cpox coproporphyrinogen oxidase ISO protein:decreased activity:liver (rat) RGD PMID:9173682 RGD:1600958 NCBI chrNW_004936630:4,412,099...4,424,867
Ensembl chrNW_004936630:4,412,273...4,425,520 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:17550594 RGD:1626231 NCBI chrNW_004936541:2,288,847...2,333,129
Ensembl chrNW_004936541:2,288,841...2,331,689 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19330884 NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606 		JBrowse link
G Csf1 colony stimulating factor 1 ISO protein:increased expression:dorsal root ganglion RGD PMID:32510872 RGD:127338469 NCBI chrNW_004936704:1,372,137...1,393,355
Ensembl chrNW_004936704:1,378,103...1,393,542 		JBrowse link
G Csf1r colony stimulating factor 1 receptor treatment ISO RGD PMID:18434589 RGD:151665814 NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:12742377 RGD:11039465 NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487 		JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chrNW_004936471:33,757,778...33,777,871
Ensembl chrNW_004936471:33,757,772...33,778,933 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:7543497 PMID:22354915 RGD:7204500 RGD:7204519 NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643 		JBrowse link
G Ctsk cathepsin K ISO mRNA:increased expression:synovium, bone marrow RGD PMID:15353610 RGD:1601025 NCBI chrNW_004936580:1,022,762...1,038,020
Ensembl chrNW_004936580:1,022,762...1,034,984 		JBrowse link
G Ctss cathepsin S ISO RGD PMID:21439785 RGD:5686915 NCBI chrNW_004936580:963,176...991,732
Ensembl chrNW_004936580:963,153...991,442 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:11465708 RGD:4892002 NCBI chrNW_004936475:9,443,851...9,454,715
Ensembl chrNW_004936475:9,443,733...9,455,062 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:spinal cord RGD PMID:11465708 PMID:17123734 RGD:4891969 RGD:4892002 NCBI chrNW_004936473:28,508,726...28,535,640
Ensembl chrNW_004936473:28,510,523...28,535,627 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO RGD PMID:24819400 RGD:150519886 NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) ISO RGD PMID:15182735 RGD:2316231 NCBI chrNW_004936475:21,863,627...21,877,660
Ensembl chrNW_004936475:21,862,166...21,877,711 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194984 NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416 		JBrowse link
G Drd1 dopamine receptor D1 treatment ISO mRNA:increased expression:corpus striatum (rat) RGD PMID:23762129 RGD:7248592 NCBI chrNW_004936609:790,647...795,187
Ensembl chrNW_004936609:792,276...793,613 		JBrowse link
G Drd2 dopamine receptor D2 treatment ISO mRNA:increased expression:corpus striatum (rat) RGD PMID:23762129 RGD:7248592 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Edn1 endothelin 1 ISO mRNA:increased expression:inguinal lymph node (mouse) RGD PMID:22249931 RGD:8661695 NCBI chrNW_004936534:885,489...892,292
Ensembl chrNW_004936534:885,287...891,772 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: therapeutic CTD PMID:7589090 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528 		JBrowse link
G Esr1 estrogen receptor 1 treatment ISO associated with Osteoporosis RGD PMID:20112355 RGD:10045851 NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:16269464 RGD:5508854 NCBI chrNW_004936495:7,956,168...8,018,356
Ensembl chrNW_004936495:7,956,766...8,004,357 		JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21436072 RGD:5147764 NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650 		JBrowse link
G F2r coagulation factor II thrombin receptor severity ISO RGD PMID:19674841 RGD:7387269 NCBI chrNW_004936549:226,508...247,024
Ensembl chrNW_004936549:225,371...247,042 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:12511586 RGD:735010 NCBI chrNW_004936549:142,281...153,575
Ensembl chrNW_004936549:141,512...153,602 		JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:22354915 RGD:7204500 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:dorsal root ganglion		 CTD
RGD		 PMID:12875993 PMID:16670289 PMID:32510872 RGD:127338469 RGD:9685708 NCBI chrNW_004936580:115,552...144,970
Ensembl chrNW_004936580:115,450...145,785 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO RGD PMID:23341540 RGD:11344930 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Fgf8 fibroblast growth factor 8 ISO RGD PMID:18699993 RGD:2314157 NCBI chrNW_004936600:4,004,847...4,010,626
Ensembl chrNW_004936600:4,004,824...4,010,689 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 ISO RGD PMID:22833219 RGD:10402072 NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508 		JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO RGD PMID:19180491 RGD:6483591 NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041 		JBrowse link
G Flt3 fms related receptor tyrosine kinase 3 ISO RGD PMID:10857786 RGD:61066 NCBI chrNW_004936472:23,169,967...23,239,178
Ensembl chrNW_004936472:23,170,470...23,256,904 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment ISO RGD PMID:24186846 RGD:405650594 NCBI chrNW_004936488:4,384,710...4,388,118
Ensembl chrNW_004936488:4,384,705...4,388,122 		JBrowse link
G Foxp3 forkhead box P3 treatment ISO mRNA,protein:decreased expression:lung RGD PMID:23643080 PMID:29264841 RGD:38549364 RGD:38599003 NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308 		JBrowse link
G Gja1 gap junction protein alpha 1 ISO RGD PMID:23165424 RGD:7207259 NCBI chrNW_004936658:3,920,043...3,932,987
Ensembl chrNW_004936658:3,920,043...3,932,987 		JBrowse link
G Gli1 GLI family zinc finger 1 treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chrNW_004936646:1,622,308...1,629,787
Ensembl chrNW_004936646:1,622,308...1,629,779 		JBrowse link
G Gpi glucose-6-phosphate isomerase ISO RGD PMID:23911657 RGD:11051957 NCBI chrNW_004936570:1,582,120...1,608,537
Ensembl chrNW_004936570:1,579,372...1,608,788 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 disease_progression
treatment		 ISO protein:increased expression:aorta (rat)
protein:altered expression:T cell (rat)		 RGD PMID:28349925 PMID:28631356 PMID:28653218 RGD:13513975 RGD:13513976 RGD:13513979 NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147 		JBrowse link
G Grn granulin precursor ISO RGD PMID:21393509 RGD:5509782 NCBI chrNW_004936541:793,548...800,271
Ensembl chrNW_004936541:793,523...800,217 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16713974 NCBI chrNW_004936536:6,730,070...6,893,818
Ensembl chrNW_004936536:6,730,062...6,894,303 		JBrowse link
G Gusb glucuronidase beta treatment ISO RGD PMID:827200 RGD:42724460 NCBI chrNW_004936543:7,721,273...7,732,468
Ensembl chrNW_004936543:7,721,763...7,731,897 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO mRNA,protein:altered expression:bone: RGD PMID:25264706 RGD:9686117 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G Hdac6 histone deacetylase 6 treatment ISO RGD PMID:23541634 RGD:9681550 NCBI chrNW_004936721:757,500...778,416
Ensembl chrNW_004936721:758,181...778,053 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:21679445 RGD:8693318 NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:altered localization:cytoplasm, extracellular matrix RGD PMID:12384917 RGD:728698 NCBI chrNW_004936472:25,236,728...25,246,585
Ensembl chrNW_004936472:25,236,728...25,246,580 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17119970 RGD:5508468 NCBI chrNW_004936549:1,378,536...1,400,501
Ensembl chrNW_004936549:1,378,736...1,400,532 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:10882416 PMID:15529360 RGD:12910542 RGD:1624244 NCBI chrNW_004936506:1,678,069...1,687,632 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:7774621 PMID:12412757 PMID:19203382 PMID:22450443 RGD:10755750 RGD:2311498 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452 		JBrowse link
G Igf1 insulin like growth factor 1 ISO protein:decreased expression:plasma RGD PMID:19246225 RGD:2306697 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351 		JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO mRNA, protein:increased expression:kidney, serum RGD PMID:14642797 RGD:10402760 NCBI chrNW_004936478:20,511,490...20,518,251
Ensembl chrNW_004936478:20,510,137...20,518,306 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:19652024 PMID:21087862 RGD:7495772 RGD:7495778 NCBI chrNW_004936785:358,128...406,751
Ensembl chrNW_004936785:356,168...406,773 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment ISO RGD PMID:16684367 RGD:12791276 NCBI chrNW_004936809:1,280,254...1,306,964
Ensembl chrNW_004936809:1,257,654...1,301,813 		JBrowse link
G Il10 interleukin 10 treatment ISO protein:decreased expression:serum:
CTD Direct Evidence: marker/mechanism|therapeutic		 RGD
CTD		 PMID:15270736 PMID:19169271 PMID:19193354 PMID:20974942 PMID:22052031 More... RGD:1626677 RGD:2311059 RGD:7193038 RGD:7364838 RGD:8662976 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502 		JBrowse link
G Il13 interleukin 13 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:10444273 PMID:11860705 PMID:17665443 RGD:4889497 RGD:8549606 NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373 		JBrowse link
G Il15 interleukin 15 ISO RGD PMID:20188418 RGD:5000761 NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197 		JBrowse link
G Il17a interleukin 17A treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)		 RGD
CTD		 PMID:20925596 PMID:20974942 PMID:21194185 PMID:23377547 RGD:4781444 RGD:9068936 RGD:9130803 NCBI chrNW_004936476:8,621,860...8,625,008
Ensembl chrNW_004936476:8,621,860...8,625,008 		JBrowse link
G Il18 interleukin 18 disease_progression ISO RGD PMID:15147345 PMID:19096963 RGD:4889415 RGD:4889503 NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189 		JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:serum: RGD PMID:19169271 PMID:20379758 RGD:6907373 RGD:8662976 NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315 		JBrowse link
G Il1b interleukin 1 beta treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)		 RGD
CTD		 PMID:19330884 PMID:20131233 PMID:20974942 PMID:21557995 PMID:22450443 More... RGD:10755447 RGD:13792834 RGD:7175317 RGD:7193038 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Il1rl1 interleukin 1 receptor like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20472598 NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human gene in a rat model
mRNA:increased expression:popliteal lymph node (rat)
rat model treated with human protein
mouse model treated with human protein		 RGD PMID:10921508 PMID:12727108 PMID:15270736 PMID:22267332 PMID:23006786 RGD:1626677 RGD:6907376 RGD:8549801 RGD:8551741 RGD:8551745 NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340 		JBrowse link
G Il2 interleukin 2 treatment ISO protein:increased expression:serum: RGD PMID:2492102 PMID:19169271 RGD:10047055 RGD:8662976 NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625 		JBrowse link
G Il20 interleukin 20 ISO RGD PMID:20722035 RGD:5147393 NCBI chrNW_004936557:5,749,419...5,751,776
Ensembl chrNW_004936557:5,749,419...5,751,776 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:17928458 RGD:2325988 NCBI chrNW_004936484:8,514,333...8,555,392
Ensembl chrNW_004936484:8,544,062...8,555,332 		JBrowse link
G Il33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20472598 NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470 		JBrowse link
G Il6 interleukin 6 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:8607900 PMID:10381487 PMID:20131233 PMID:20974942 PMID:22450443 More... RGD:10755447 RGD:11049551 RGD:11049553 RGD:11060267 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO RGD PMID:20626857 RGD:5509945 NCBI chrNW_004936480:11,867,573...11,913,563
Ensembl chrNW_004936480:11,884,582...11,909,635 		JBrowse link
G Itga4 integrin subunit alpha 4 treatment ISO RGD PMID:12969328 RGD:9698440 NCBI chrNW_004936509:10,215,283...10,293,653
Ensembl chrNW_004936509:10,215,283...10,292,252 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:8881759 RGD:6482229 NCBI chrNW_004936778:1,286,475...1,311,184
Ensembl chrNW_004936778:1,286,341...1,311,194 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO protein:increased expression:endothelial cell RGD PMID:16869003 RGD:2317300 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO RGD PMID:19265135 RGD:6482234 NCBI chrNW_004936485:8,857,688...8,894,270
Ensembl chrNW_004936485:8,857,669...8,895,315 		JBrowse link
G Jak1 Janus kinase 1 treatment ISO RGD PMID:29452839 RGD:19165139 NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO RGD PMID:22339472 PMID:22800927 PMID:23711144 RGD:10403066 RGD:10403074 RGD:10403081 NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867 		JBrowse link
G Jak3 Janus kinase 3 treatment ISO RGD PMID:18234077 PMID:21434883 PMID:25762693 RGD:11533938 RGD:11533942 RGD:11533944 NCBI chrNW_004936596:3,212,593...3,224,426
Ensembl chrNW_004936596:3,212,593...3,224,048 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO RGD PMID:25131209 RGD:150521609 NCBI chrNW_004936706:940,585...952,484 JBrowse link
G Klkb1 kallikrein B1 ISO RGD PMID:9783057 PMID:22739815 RGD:7297047 RGD:7327138 NCBI chrNW_004936554:3,227,395...3,256,710
Ensembl chrNW_004936554:3,228,735...3,256,710 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 ISO RGD PMID:16984225 RGD:2306289 NCBI chrNW_004936487:16,299,054...16,344,587
Ensembl chrNW_004936487:16,297,991...16,344,745 		JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15142272 NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334 		JBrowse link
G Lgals3 galectin 3 ISO RGD PMID:16507131 RGD:1625684 NCBI chrNW_004936697:20,861...38,568
Ensembl chrNW_004936697:27,145...38,586 		JBrowse link
G LOC101959212 alpha-2-macroglobulin ISO protein:increased expression:serum RGD PMID:6163339 RGD:10046032 NCBI chrNW_004936870:424,832...468,303
Ensembl chrNW_004936870:424,951...468,167 		JBrowse link
G LOC101960095 antileukoproteinase treatment ISO protein:decreased expression:articular cartilage of joint RGD PMID:9744360 PMID:10449524 RGD:634208 RGD:9999431 NCBI chrNW_004936514:7,618,382...7,620,790
Ensembl chrNW_004936514:7,618,261...7,620,912 		JBrowse link
G LOC101964209 C-C chemokine receptor type 1 ISO RGD PMID:14674010 PMID:18608173 RGD:1582346 RGD:5688144 NCBI chrNW_004936596:177,774...183,186
Ensembl chrNW_004936596:177,812...183,186 		JBrowse link
G LOC101968921 angiotensin-converting enzyme ISO RGD PMID:20213806 RGD:2325221 NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177 		JBrowse link
G LOC101973421 amine oxidase copper containing 3 ISO RGD PMID:16947396 RGD:2313925 NCBI chrNW_004936490:17,549,836...17,564,867 JBrowse link
G LOC101976500 haptoglobin ISO mRNA, protein:increased expression:tendon, ankle
protein:increased expression:serum		 RGD PMID:12801280 PMID:15899029 RGD:1626370 RGD:1626375 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:16331767 RGD:10412332 NCBI chrNW_004936560:3,988,696...4,197,953
Ensembl chrNW_004936560:3,989,420...4,197,501 		JBrowse link
G Mif macrophage migration inhibitory factor ISO RGD PMID:10765927 RGD:1642012 NCBI chrNW_004936619:1,207,058...1,208,010
Ensembl chrNW_004936619:1,203,746...1,208,442 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:21108488 PMID:21288455 PMID:24011916 RGD:7207362 RGD:7207365 RGD:8549748 NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857 		JBrowse link
G Mmp13 matrix metallopeptidase 13 treatment ISO RGD PMID:11435459 PMID:24244039 RGD:1582329 RGD:8694124 NCBI chrNW_004936551:5,040,084...5,050,384
Ensembl chrNW_004936551:5,040,084...5,050,384 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:cartilage, serum, synovial fluid RGD PMID:17463159 RGD:1642035 NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:22391142 RGD:10041007 NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ISO RGD PMID:20131263 RGD:8552884 NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372 		JBrowse link
G Myod1 myogenic differentiation 1 treatment ISO RGD PMID:23781298 RGD:9686078 NCBI chrNW_004936528:1,407,187...1,409,683
Ensembl chrNW_004936528:1,407,661...1,409,573 		JBrowse link
G Myog myogenin treatment ISO RGD PMID:23781298 RGD:9686078 NCBI chrNW_004936567:1,507,042...1,509,814
Ensembl chrNW_004936567:1,507,042...1,509,815 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 severity ISO DNA:missense mutations:cds:p.M106V, p.M153T (rat) RGD PMID:12461526 RGD:628543 NCBI chrNW_004936543:3,617,369...3,630,990
Ensembl chrNW_004936543:3,617,372...3,630,997 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:20131263 PMID:21424514 RGD:5508728 RGD:8552884 NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO protein:increased expression:ankle joint (mouse) RGD PMID:12826065 PMID:21880869 RGD:1358527 RGD:5509060 NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO RGD PMID:29337196 RGD:13504725 NCBI chrNW_004936527:6,427,147...6,445,770
Ensembl chrNW_004936527:6,427,093...6,446,534 		JBrowse link
G Npsr1 neuropeptide S receptor 1 treatment ISO RGD PMID:24884567 RGD:9831205 NCBI chrNW_004936478:10,352,894...10,542,949
Ensembl chrNW_004936478:10,352,741...10,544,102 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 severity ISO RGD PMID:16905546 RGD:11073695 NCBI chrNW_004936475:19,771,384...19,785,034
Ensembl chrNW_004936475:19,769,488...19,785,311 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1 group H member 2 ISO RGD PMID:21859686 RGD:6480864 NCBI chrNW_004936889:223,137...229,968
Ensembl chrNW_004936889:223,101...229,990 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO RGD PMID:21859686 RGD:6480864 NCBI chrNW_004936562:1,937,665...1,946,680
Ensembl chrNW_004936562:1,937,667...1,946,669 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO RGD PMID:18706093 RGD:2300006 NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590 		JBrowse link
G Nts neurotensin ISO RGD PMID:8518953 RGD:9743903 NCBI chrNW_004936507:3,318,982...3,329,248
Ensembl chrNW_004936507:3,318,915...3,329,342 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:22028806 RGD:6480518 NCBI chrNW_004936758:1,581,828...1,624,332
Ensembl chrNW_004936758:1,581,897...1,592,222 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase ISO RGD PMID:17138865 RGD:6483527 NCBI chrNW_004936523:1,492,795...1,786,942
Ensembl chrNW_004936523:1,493,450...1,750,524 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 severity ISO RGD PMID:16356201 RGD:5684009 NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642 		JBrowse link
G Pdyn prodynorphin treatment ISO RGD PMID:25102697 RGD:401851905 NCBI chrNW_004936485:16,559,371...16,571,461
Ensembl chrNW_004936485:16,559,217...16,571,678 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 severity ISO protein:increased expression:knee joint, blood vessels (mouse) RGD PMID:14613294 PMID:21982514 PMID:22548760 RGD:6484738 RGD:6771177 RGD:6771222 NCBI chrNW_004936541:4,873,459...4,919,787
Ensembl chrNW_004936541:4,873,182...4,937,500 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:19180491 RGD:6483591 NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO RGD PMID:18412166 RGD:6482696 NCBI chrNW_004936623:3,672,201...3,696,959 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18412166 PMID:20374644 RGD:6482684 RGD:6482696 NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258 		JBrowse link
G Plau plasminogen activator, urokinase ISO RGD PMID:20973954 RGD:6483801 NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877 		JBrowse link
G Pomc proopiomelanocortin treatment ISO RGD PMID:25102697 RGD:401851905 NCBI chrNW_004936493:7,060,747...7,065,276
Ensembl chrNW_004936493:7,061,587...7,065,109 		JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: therapeutic CTD PMID:36181686 NCBI chrNW_004936564:2,594,362...2,690,680
Ensembl chrNW_004936564:2,667,660...2,690,683 		JBrowse link
G Ptch1 patched 1 treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476 		JBrowse link
G Ptger4 prostaglandin E receptor 4 disease_progression
treatment		 ISO mRNA:increased expression:tarsal joint, synovium (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11207665 PMID:18287210 PMID:20423341 RGD:10003041 RGD:10003052 RGD:10043377 NCBI chrNW_004936518:1,903,636...1,916,746
Ensembl chrNW_004936518:1,903,725...1,916,746 		JBrowse link
G Ptges prostaglandin E synthase ISO mRNA, protein:increased expression:paw RGD PMID:12707354 RGD:2300108 NCBI chrNW_004936487:16,959,263...16,968,909
Ensembl chrNW_004936487:16,959,231...16,968,922 		JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO mRNA:increased expression:paw (rat) RGD PMID:12707354 RGD:2300108 NCBI chrNW_004936646:969,674...990,532 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO mRNA, protein:increased expression:synovium RGD PMID:22289897 RGD:5687744 NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:autopod joint
mRNA, protein:increased expression:synovium		 RGD PMID:18758904 PMID:21765105 PMID:22289897 RGD:2300221 RGD:5508310 RGD:5687744 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO protein:increased expression:metatarsophalangeal joint, mononuclear cell (rat) RGD PMID:24998229 RGD:11532752 NCBI chrNW_004936690:2,180,804...2,232,869
Ensembl chrNW_004936690:2,181,047...2,232,958 		JBrowse link
G Rag2 recombination activating 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20974942 NCBI chrNW_004936533:1,801,207...1,807,431
Ensembl chrNW_004936533:1,801,391...1,807,431 		JBrowse link
G S100a8 S100 calcium binding protein A8 ISO RGD PMID:8343166 RGD:633930 NCBI chrNW_004936580:3,256,399...3,256,913
Ensembl chrNW_004936580:3,256,417...3,256,913 		JBrowse link
G S100a9 S100 calcium binding protein A9 ISO RGD PMID:8343166 RGD:633930 NCBI chrNW_004936580:3,228,097...3,230,652
Ensembl chrNW_004936580:3,228,092...3,230,676 		JBrowse link
G Serpinc1 serpin family C member 1 ISO protein:decreased expression:plasma RGD PMID:22781611 RGD:11035273 NCBI chrNW_004936481:13,981,014...13,993,750
Ensembl chrNW_004936481:13,981,019...13,993,634 		JBrowse link
G Sfrp4 secreted frizzled related protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194984 NCBI chrNW_004936478:13,257,183...13,266,972
Ensembl chrNW_004936478:13,257,801...13,266,701 		JBrowse link
G Shh sonic hedgehog signaling molecule treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 severity ISO RGD PMID:17122779 RGD:5684943 NCBI chrNW_004936569:888,309...895,991
Ensembl chrNW_004936569:887,742...895,977 		JBrowse link
G Smo smoothened, frizzled class receptor treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:mononuclear cell RGD PMID:16507131 RGD:1625684 NCBI chrNW_004936594:2,932,297...2,935,358
Ensembl chrNW_004936594:2,933,747...2,934,451 		JBrowse link
G Spn sialophorin ISO associated with Staphylococcal Infections RGD PMID:7927732 RGD:2303983 NCBI chrNW_004936501:12,773,967...12,776,642 JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO protein:increased tyrosine phosphorylation:macrophage, synovial cell
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:14674010 PMID:15188379 RGD:1582346 NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15188379 PMID:21937456 PMID:23711144 RGD:10403081 NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402 		JBrowse link
G Tac1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9259450 NCBI chrNW_004936585:2,932,783...2,941,141
Ensembl chrNW_004936585:2,932,727...2,941,384 		JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO RGD PMID:29763498 RGD:15036801 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272 		JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO protein:increased expression:synovium RGD PMID:9010265 RGD:1601623 NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:16879225 RGD:5685015 NCBI chrNW_004936620:2,563,900...2,568,117 JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO RGD PMID:12483743 RGD:2290463 NCBI chrNW_004936602:1,488,993...1,496,108
Ensembl chrNW_004936602:1,489,545...1,495,478 		JBrowse link
G Tjp1 tight junction protein 1 ISO RGD PMID:18848892 RGD:2325138 NCBI chrNW_004936483:1,814,870...2,045,802
Ensembl chrNW_004936483:1,814,894...2,030,946 		JBrowse link
G Tlr2 toll like receptor 2 ISO RGD PMID:20131263 PMID:21725847 RGD:7241099 RGD:8552884 NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788 		JBrowse link
G Tlr3 toll like receptor 3 ISO mRNA, protein:increased expression:spleen (rat) RGD PMID:20500834 RGD:5128706 NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907 		JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:		 CTD
RGD		 PMID:7589090 PMID:9598899 PMID:19169271 PMID:19203382 PMID:19330884 More... RGD:10450611 RGD:10755447 RGD:13792834 RGD:7193038 RGD:7245941 RGD:8661761 RGD:8662976 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b treatment ISO CTD Direct Evidence: therapeutic
Sinomenine CHEBI:9163
mRNA:decreased expression:bone		 CTD
RGD		 PMID:16696922 PMID:23333834 PMID:24066131 RGD:1624171 RGD:42721982 NCBI chrNW_004936470:27,571,263...27,598,725
Ensembl chrNW_004936470:27,571,270...27,599,089 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO RGD PMID:20370892 PMID:21690068 PMID:23052485 RGD:7245941 RGD:8661729 RGD:8661761 NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B treatment ISO human protein in rat model RGD PMID:21463515 PMID:21690068 PMID:23052485 RGD:5131255 RGD:7245941 RGD:8661761 NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177 		JBrowse link
G Trpv2 transient receptor potential cation channel subfamily V member 2 treatment ISO RGD PMID:25869297 RGD:9999444 NCBI chrNW_004936821:198,622...225,575
Ensembl chrNW_004936821:198,098...226,025 		JBrowse link
G Txndc5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23326410 NCBI chrNW_004936534:4,679,636...4,706,682
Ensembl chrNW_004936534:4,679,631...4,706,309 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:9598899 PMID:26221077 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673 		JBrowse link
G Vim vimentin ISO RGD PMID:7516431 RGD:6480480 NCBI chrNW_004936520:10,051,692...10,059,324
Ensembl chrNW_004936520:10,052,012...10,059,182 		JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:19055696 PMID:21998117 RGD:5685376 RGD:5685612 NCBI chrNW_004936489:5,425,778...5,434,483
Ensembl chrNW_004936489:5,425,726...5,434,785 		JBrowse link
G Xdh xanthine dehydrogenase ISO protein:increased expression:brain, mitochondrion RGD PMID:25870945 RGD:13208957 NCBI chrNW_004936493:1,762,814...1,824,501
Ensembl chrNW_004936493:1,762,869...1,823,238 		JBrowse link
G Xylt1 xylosyltransferase 1 ISO mRNA:decreased expression:articular cartilage RGD PMID:19001053 RGD:2313142 NCBI chrNW_004936501:4,164,714...4,337,604
Ensembl chrNW_004936501:4,187,213...4,331,783 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14499
    Animal Diseases 1219
      Animal Disease Models 1180
        Experimental Arthritis 198
Path 2
Term Annotations click to browse term
  disease 14499
    disease of anatomical entity 14148
      Skin and Connective Tissue Diseases 6479
        connective tissue disease 5036
          bone disease 3704
            bone inflammation disease 1240
              arthropathy 1220
                arthritis 813
                  Experimental Arthritis 198
paths to the root