LOC101960095 (antileukoproteinase)

Gene: LOC101960095 (antileukoproteinase) Ictidomys tridecemlineatus

Analyze

Symbol:

LOC101960095 (Ensembl: SLPI)

Name:

antileukoproteinase (Ensembl:secretory leukocyte peptidase inhibitor)

RGD ID:

12544293

Description:

ENCODES a protein that exhibits DNA binding (inferred); endopeptidase inhibitor activity (inferred); enzyme binding (inferred); INVOLVED IN antibacterial humoral response (inferred); immune response (inferred); innate immune response (inferred); ASSOCIATED WITH Acute Lung Injury (ortholog); Chemical and Drug Induced Liver Injury (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); Golgi apparatus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

secretory leukocyte peptidase inhibitor; Slpi

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	192,165,015 - 192,167,144 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	7,618,261 - 7,620,912 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	7,618,382 - 7,620,790 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antibacterial humoral response (IEA)

immune response (IEA)

innate immune response (IEA)

modulation of process of another organism (IEA)

negative regulation of viral genome replication (IEA)

response to lipopolysaccharide (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

Golgi apparatus (IEA)

Molecular Function

DNA binding (IEA)

endopeptidase inhibitor activity (IEA)

enzyme binding (IEA)

mRNA binding (IEA)

peptidase inhibitor activity (IEA)

protein binding (ISO)

serine-type endopeptidase inhibitor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC101960095
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	192,165,015 - 192,167,144 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	7,618,261 - 7,620,912 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	7,618,382 - 7,620,790 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLPI
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	45,252,239 - 45,254,564 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	45,252,239 - 45,254,564 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	43,880,880 - 43,883,205 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	43,314,293 - 43,316,620 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	43,314,292 - 43,316,620	NCBI
Celera	20	40,589,481 - 40,591,808 (-)	NCBI		Celera
Cytogenetic Map	20	q13.12	NCBI
HuRef	20	40,622,786 - 40,625,111 (-)	NCBI		HuRef
CHM1_1	20	43,783,432 - 43,785,757 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	46,988,133 - 46,990,454 (-)	NCBI		T2T-CHM13v2.0

Slpi
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	164,195,990 - 164,231,086 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	164,195,990 - 164,231,015 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	164,354,070 - 164,356,507 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	164,354,070 - 164,389,095 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	164,179,806 - 164,182,243 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	164,045,511 - 164,064,154 (-)	NCBI		MGSCv36	mm8
Celera	2	170,287,487 - 170,289,924 (-)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	85.16	NCBI

Slpi
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	173,501,573 - 173,503,822 (-)	NCBI		GRCr8
mRatBN7.2	3	153,082,208 - 153,084,457 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	153,082,369 - 153,084,453 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	156,892,395 - 156,894,639 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	165,391,330 - 165,393,574 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	163,136,592 - 163,138,836 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	160,799,979 - 160,802,228 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	160,799,981 - 160,802,433 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	166,981,037 - 166,983,286 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	155,373,825 - 155,376,074 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	155,279,861 - 155,282,110 (-)	NCBI
Celera	3	151,693,623 - 151,695,872 (-)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

SLPI
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	50,985,903 - 51,026,936 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	50,979,011 - 51,020,044 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	41,583,429 - 41,585,773 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	42,673,417 - 42,675,773 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	42,673,417 - 42,675,773 (-)	Ensembl	panpan1.1		panPan2

SLPI
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	32,566,030 - 32,568,406 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	32,566,026 - 32,568,420 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	32,210,966 - 32,213,346 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	33,276,396 - 33,278,776 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	33,276,396 - 33,278,790 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	32,537,713 - 32,540,093 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	32,653,063 - 32,655,444 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	33,196,545 - 33,198,948 (-)	NCBI		UU_Cfam_GSD_1.0

SLPI
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	47,595,803 - 47,598,387 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	47,595,804 - 47,598,364 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	53,167,238 - 53,169,798 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLPI
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	18,579,549 - 18,581,897 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	18,579,515 - 18,582,076 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	67,222,449 - 67,224,808 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slpi
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	9,235,650 - 9,239,231 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624790	9,235,830 - 9,238,562 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005325385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000024433 ⟹ ENSSTOP00000018892

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936514	7,618,261 - 7,620,912 (+)	Ensembl

RefSeq Acc Id:

XM_005325385 ⟹ XP_005325442

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	192,165,015 - 192,167,144 (+)	NCBI
SpeTri2.0	NW_004936514	7,618,382 - 7,620,790 (+)	NCBI

Sequence:

show sequence

CGCAGCCGACCTCTCCGCCCTCTTCCATGTGCAAGACTAAAGGGCTGCTTCCTCACGATGCTCA
GGCTCAGACAGACGTCCCCAACGGCCTCCTTATCAGTCTGGTGGCAACCTCTTCTCTGATGGTT
ACTCTCTTGGTCTCAGAGTCCCGTCTGAAACAGGAAAGGGCTGCCATCTCCCTGGTCTCATGAT
TTTTGGTCTCTGGCTGAGCTTCCTGCCGGGAGCAGCAGCAGCTGGGAGGAGCCAAAACCTTCTG
TTGGGGGCCACACCCACTGGCAAAGGTATAAACAGTGAGCTTTGGCGCTGGCTGTCAGAGCCAC
CTGCCTGCACCATGAAGTCCAGCAGCCTCTTGCCACTCGTGGTGCTTCTTGCCCTGGGAACTCT
GGCTCCTTTGGCTGTGGAAGGTTCTGGAAATGAATCTCTGAAAGCCGGAGCCTGCCCTGCTAGA
CCACAAGTCCGGTGCTTGCGATATGAGGAGCCCGCGTGCCAGACTGACTGGCAGTGTCCGGGGA
AGCAGAGATGTTGCCCTGATTATTGTGGCATCAAATGCTTAGATCCTGTTGCCATCCCCAGACC
AGTGGAGAGGAAGCCTGGGAAGTGCCCAGTGGTCAAGGCTCAGTGTATGATGCTTAACCCCCCC
AACCGCTGTGAGACGGACAGCCAGTGTGACAGGGACTTCAAGTGCTGCCTCGGCATGTGCGGGA
AGCTCTGCCTTCCCCCCGTGAGAGCTTGATTCCTGCGTTGGAGGTGCCTCTGGGTTCCTAGTCT
GTGTGGTGTGGGGACTCCCTTTCTGCTGCCAGGTGGGATTCTGTGGTGAGGACTTGGCTCCTGC
ACCCGTATCTCCTTTTGGCAAGCACTTAGTACCCAGGGGGCTTTCAGGAGATATGTTAATGAGT
GAATAAGTAAATAAACTTATTTCTCTGTGTACAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005325442	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000018892.2
GenBank Protein	KAG3263571	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005325442 ⟸ XM_005325385
- UniProtKB:	I3N3E6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIFGLWLSFLPGAAAAGRSQNLLLGATPTGKGINSELWRWLSEPPACTMKSSSLLPLVVLLALG TLAPLAVEGSGNESLKAGACPARPQVRCLRYEEPACQTDWQCPGKQRCCPDYCGIKCLDPVAIP RPVERKPGKCPVVKAQCMMLNPPNRCETDSQCDRDFKCCLGMCGKLCLPPVRA hide sequence

RefSeq Acc Id:

ENSSTOP00000018892 ⟸ ENSSTOT00000024433

Protein Domains

WAP

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000020296	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000024433.2	UniProtKB/TrEMBL
Gene3D-CATH	4.10.75.10	UniProtKB/TrEMBL
InterPro	Elafin-like_sf	UniProtKB/TrEMBL
	WAP_dom	UniProtKB/TrEMBL
NCBI Gene	LOC101960095	ENTREZGENE
PANTHER	ANTILEUKOPROTEINASE	UniProtKB/TrEMBL
	WHEY ACDIC PROTEIN WAP	UniProtKB/TrEMBL
Pfam	WAP	UniProtKB/TrEMBL
PRINTS	4DISULPHCORE	UniProtKB/TrEMBL
PROSITE	WAP	UniProtKB/TrEMBL
SMART	WAP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57256	UniProtKB/TrEMBL
UniProt	I3N3E6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-26	LOC101960095	antileukoproteinase	Slpi	secretory leukocyte peptidase inhibitor	Symbol and/or name change	5135510	APPROVED
2017-07-13	Slpi	secretory leukocyte peptidase inhibitor	LOC101960095	antileukoproteinase	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD