Adam17 (ADAM metallopeptidase domain 17)

Gene: Adam17 (ADAM metallopeptidase domain 17) Ictidomys tridecemlineatus

Analyze

Symbol:

Adam17

Name:

ADAM metallopeptidase domain 17

RGD ID:

12447518

Description:

ENCODES a protein that exhibits cytokine binding (ortholog); metallodipeptidase activity (ortholog); INVOLVED IN B cell differentiation (ortholog); cell motility (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; interleukin-6 signaling pathway; Notch signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); atopic dermatitis (ortholog); Blister (ortholog); FOUND IN apical part of cell (ortholog); cell surface (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ADAM metallopeptidase domain 17, transcript variant X1; ADAM metallopeptidase domain 17, transcript variant X2; ADAM metallopeptidase domain 17, transcript variant X3; disintegrin and metalloproteinase domain-containing protein 17

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	51,109,736 - 51,148,960 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936532	5,864,867 - 5,904,003 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936532	5,864,851 - 5,904,005 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

atopic dermatitis (ISO)

Blister (ISO)

Brain Hypoxia (ISO)

colitis (ISO)

congestive heart failure (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Experimental Colitis (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Kidney Reperfusion Injury (ISO)

Left Ventricular Hypertrophy (ISO)

Neonatal Inflammatory Skin and Bowel Disease 1 (ISO)

Pneumococcal Meningitis (ISO)

renal fibrosis (ISO)

syndromic microphthalmia 5 (ISO)

thoracic aortic aneurysm (ISO)

type 2 diabetes mellitus (ISO)

ureteral obstruction (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amyloid precursor protein catabolic process (IEA)

B cell differentiation (ISO)

cell adhesion (IEA)

cell adhesion mediated by integrin (IEA)

cell motility (ISO)

cellular response to high density lipoprotein particle stimulus (IEA)

cellular response to mechanical stimulus (ISO)

commissural neuron axon guidance (IEA)

defense response to Gram-positive bacterium (IEA)

germinal center formation (ISO)

membrane protein ectodomain proteolysis (IEA,ISO)

negative regulation of apoptotic process (ISO)

negative regulation of cold-induced thermogenesis (ISO)

negative regulation of neuron projection development (ISO)

negative regulation of transforming growth factor beta receptor signaling pathway (IEA)

Notch receptor processing (IEA)

Notch signaling pathway (IEA)

positive regulation of apoptotic process (ISO)

positive regulation of blood vessel endothelial cell migration (IEA)

positive regulation of cell growth (IEA)

positive regulation of cell migration (IEA)

positive regulation of cell population proliferation (IEA)

positive regulation of chemokine production (IEA)

positive regulation of epidermal growth factor receptor signaling pathway (IEA,ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of G1/S transition of mitotic cell cycle (IEA)

positive regulation of neuron projection development (ISO)

positive regulation of T cell chemotaxis (IEA)

positive regulation of tumor necrosis factor production (ISO)

positive regulation of tumor necrosis factor-mediated signaling pathway (IEA)

positive regulation of vascular endothelial cell proliferation (IEA)

production of molecular mediator involved in inflammatory response (ISO)

protein processing (IEA)

proteolysis (IEA)

receptor transactivation (ISO)

regulation of axon regeneration (ISO)

regulation of cellular component organization (IEA)

regulation of mast cell apoptotic process (ISO)

regulation of neuron migration (ISO)

response to antineoplastic agent (ISO)

response to hypobaric hypoxia (ISO)

response to hypoxia (IEA)

response to lipopolysaccharide (IEA)

response to muscle activity (ISO)

response to nutrient levels (ISO)

response to xenobiotic stimulus (ISO)

signal release (ISO)

signaling receptor ligand precursor processing (ISO)

spermatogenesis (ISO)

spleen development (ISO)

T cell differentiation in thymus (ISO)

tumor necrosis factor-mediated signaling pathway (ISO)

wound healing, spreading of epidermal cells (IEA)

Cellular Component

actin cytoskeleton (IEA)

apical part of cell (ISO)

apical plasma membrane (IEA)

cell surface (IEA,ISO)

cell-cell junction (IEA)

cytoplasm (IEA)

cytosol (IEA)

focal adhesion (IEA)

membrane (IEA)

membrane raft (IEA)

plasma membrane (IEA,ISO)

ruffle membrane (IEA)

Molecular Function

cytokine binding (ISO)

endopeptidase activity (IEA)

integrin binding (IEA)

interleukin-6 receptor binding (IEA)

metal ion binding (IEA)

metallodipeptidase activity (ISO)

metalloendopeptidase activity (IEA)

metalloendopeptidase activity involved in amyloid precursor protein catabolic process (IEA)

metallopeptidase activity (IEA)

Notch binding (IEA)

PDZ domain binding (IEA)

protein binding (ISO)

tumor necrosis factor binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

epidermal growth factor/neuregulin signaling pathway (ISO)

interleukin-6 signaling pathway (ISO)

Notch signaling pathway (ISO)

tumor necrosis factor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Adam17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	51,109,736 - 51,148,960 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936532	5,864,867 - 5,904,003 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936532	5,864,851 - 5,904,005 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAM17
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	9,488,486 - 9,555,830 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	9,488,486 - 9,556,732 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	9,628,615 - 9,695,959 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	9,546,843 - 9,613,368 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	9,580,010 - 9,646,496	NCBI
Celera	2	9,541,264 - 9,607,791 (-)	NCBI		Celera
Cytogenetic Map	2	p25.1	NCBI
HuRef	2	9,474,897 - 9,541,735 (-)	NCBI		HuRef
CHM1_1	2	9,558,781 - 9,625,197 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	9,513,510 - 9,580,869 (-)	NCBI		T2T-CHM13v2.0

Adam17
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	21,373,510 - 21,423,633 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	21,373,510 - 21,423,633 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	21,323,509 - 21,373,632 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	21,323,509 - 21,373,632 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	21,329,370 - 21,379,452 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	21,570,005 - 21,620,083 (-)	NCBI		MGSCv36	mm8
Celera	12	19,527,967 - 19,579,463 (+)	NCBI		Celera
Cytogenetic Map	12	A1.3	NCBI
cM Map	12	8.3	NCBI

Adam17
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	46,601,583 - 46,663,690 (-)	NCBI		GRCr8
mRatBN7.2	6	40,872,936 - 40,920,700 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	40,872,856 - 40,920,639 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	41,195,035 - 41,242,751 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	41,509,725 - 41,557,442 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	40,942,985 - 40,990,706 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	43,400,525 - 43,448,280 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	43,400,528 - 43,448,280 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	60,268,228 - 60,315,989 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	41,882,432 - 41,930,755 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	41,885,557 - 41,933,881 (-)	NCBI
Celera	6	40,160,004 - 40,207,760 (-)	NCBI		Celera
Cytogenetic Map	6	q16	NCBI

Adam17
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955487	5,180,252 - 5,218,216 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955487	5,180,241 - 5,218,298 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADAM17
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	116,969,633 - 117,037,769 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	116,974,220 - 117,041,742 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	9,478,080 - 9,545,363 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	9,641,194 - 9,708,091 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	9,641,201 - 9,708,054 (-)	Ensembl	panpan1.1		panPan2

ADAM17
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	6,589,874 - 6,638,788 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	6,589,878 - 6,638,731 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	6,517,667 - 6,566,403 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	6,687,702 - 6,737,271 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	6,687,697 - 6,737,197 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	6,580,977 - 6,629,669 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	6,583,178 - 6,631,850 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	6,597,002 - 6,645,753 (-)	NCBI		UU_Cfam_GSD_1.0

ADAM17
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	126,795,426 - 126,853,995 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	126,795,513 - 126,853,995 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	135,176,533 - 135,222,632 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAM17
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	98,092,093 - 98,157,657 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	98,092,044 - 98,157,217 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	14,163,022 - 14,230,392 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adam17
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624969	212,321 - 253,328 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624969	212,089 - 254,532 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021727768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040271255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040271256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040271257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040271258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010001352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000004513 ⟹ ENSSTOP00000004050

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936532	5,865,883 - 5,904,003 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000039422 ⟹ ENSSTOP00000024566

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936532	5,864,867 - 5,904,003 (-)	Ensembl

RefSeq Acc Id:

XM_021727768 ⟹ XP_021583443

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,139,554 (-)	NCBI
SpeTri2.0	NW_004936532	5,864,851 - 5,894,562 (-)	NCBI

Sequence:

show sequence

TTTCACAAAATTTCAAAGTTGTGGTGGTGGATGGTGAAGATGAAAGCGAGTACACTGTAAAATG
GCAAGACTTCTTCAGTGGACATGTGGTTGCCACTTTGGAGATTTGTTAATGATACTGAGGACAA
AAGAATGTTAGTTTATAAGTCAGAAGATATCAAGAATGTTTCACGTTTACAGTCTCCAAAAGTA
TGTGGTTATTTAAAAGTGGATAATGAAGAGTTGCTTCCAAAAGGACTGGTAGACAGAGAGCCAC
CTGAAGAGTTTGTTCATCGAGTGAAGAGAAGAGCTGATCCTAATCCCATGAAGAACACTTGTAA
ATTATTGGTGGTAGCAGATCATCGCTTTTATAAATACATGGGCAGAGGGGAAGAAAGCACCACT
ACCAATTACTTAATAGAGCTAATTGACAGAGTTGATGACATCTATCGGAACACTTCGTGGGATA
ATGCGGGTTTTAAAGGTTATGGAATACAGATAGAGCAGATTCGCATTCTCAAGTCGCCACAAGA
GGTAAAACCTGGTGAAAGGCACTACAACATGGCAAAAAGTTACCCAAATGAAGACAAGGATGCT
TGGGATGTGAAGATGTTGCTAGAGCAATTTAGCTTTGATATAGCTGAAGAAGCATCTAAAGTCT
GCCTGGCACACCTTTTCACATATCAGGATTTCGATATGGGAACTCTTGGATTAGCTTATGTTGG
TTCTCCCAGAGCAAACAGTCATGGAGGTGTTTGTCCAAAAGCTTATTATAGTCCAGTTGGGAAG
AAAAATATCTACTTGAATAGTGGTTTGACCAGCACAAAAAATTATGGTAAAACCATCCTTACAA
AGGAAGCTGATCTTGTTACGACTCATGAATTGGGACACAATTTTGGAGCAGAACATGATCCTGA
TGGTCTAGCAGAATGTGCTCCGAATGAGGACCAGGGAGGAAAGTATGTTATGTATCCTATAGCT
GTGAGTGGTGACCATGAGAACAATAAGATGTTTTCAAACTGCAGTAAGCAGTCCATCTATAAGA
CTATTGAAAGTAAGGCCCAGGAGTGTTTTAAGGAGCGGAGCAACAAGGTGTGTGGGAACTCCAG
GGTGGATGAAGGAGAAGAATGTGACCCCGGCATCATGTACCTGAATAATGACACCTGCTGCAAT
AGCGACTGCACACTGAAACCAGGTGTACAGTGCAGTGACAGGAACAGTCCTTGCTGTAAGAACT
GTCAGTTTGAGACTGCCCAGAAGAAGTGCCAGGAGGCTATTAATGCTACCTGCAAAGGCGTGTC
TTACTGCACAGGGAACAGCAGTGAGTGTCCACCACCAGGAAATGCTGAAGATGATACAGTTTGC
TTGGACCTTGGCAAGTGTAAGGATGGGAAGTGCATCCCCTTCTGTGAGAGGGAGCAGCAGCTGG
AGCCCTGTGCGTGCAACGAAACTGACAACTCATGCAAGGTGTGCTGTAGAGACCGTTCTGGCCG
GTGTGTACCCTATGTCGACGCTGAGCAAAAGAACCTATTTTTAAGGAAAGGGAAGCCCTGTACA
GTAGGGTTTTGTGACATGAATGGCAAATGCGAGAAACGAGTACAGGATGTAATAGAGAGATTTT
GGGATTTCATTGACCAGTTGAGCATCAATACTTTTGGGAAGTTTTTAGCAGACAACATCGTAGG
ATCTGTCCTGGTTTTCTCCTTGATATTTTGGATTCCTTTCAGTATTCTTGTTCATTGTGTGGAT
AAGAAATTGGATAAGCAATATGAATCGCTGTCTCTGTTTAACCCCAGTAATGTTGAGATGTTAA
GCAGCATGGATTCGGCCTCAGTTCGAATTATCAAGCCCTTTCCTGCACCCCAGACTCCAGGCCG
CCTGCAGCCCCTACAGCCTACCCCTGTGATGCCACCAGTGTCTGCTGCTCCAAAACTGGACCAC
CAGAGAATGGACACCATCCAAGAAGACCCCAGCACAGACTCACATATGGATGAGGATGGCTTTG
AAAAGGACCCCTTCCCTAACAGTGGCACAGCTGCCAAGTCCTTTGAGGATCTCACGGACCATCC
AGTCACCAGAAGTGAAAAGGCTGCTTCCTTTAAACTGCAGCGTCAGAATCGTGTGGACAGCAAA
GAAACTGAGTGCTAGTGAGGGTCATGTCCTAAGTGATTTTGACTTACACGTGCAAATATTTTTA
TAAATTTGGCCTAGAAGCATGGCATATATCTTGTGAAGAACTGGGAGGAATAAGGAAATTACTC
AACAGCAAATGCTGGCCATGTGTTTGAGCTTCCTTCACATAAGCAGTGCTGTCTAGTTAAGACC
CTCTTCCTTTGAAAAGGTCAGGTGAATCTGGCTTATTTTCAGACTTTCAGGTTTTAGTGTTTTT
GAGTTTCAAAACAGCCTTTGACCTGGTGGTGCAAAAGCAGAAAATACAGCTGGGTTAGATTACT
GTAAATTAACCTTTATGTTGATAACAGCACTGATCTTTTATATACTGTAATGACCCTATGAGGC
ACTTAGCAGTTATTTGAGAGGACAACTGGAACAATTTTTTTTTTTCAAGTAAAGGCAAAGGAAT
GAGATAATCTATTATTGCCAAAACGTGGGTGTTTCTAGGTATTACCCAGATCTTTTCACAGCAG
GGAGAAAGCTACATCTAAACTTACAAATAATTTGGGTGAATAGGGTTTTTTTTCCTAAGGCTAG
TGCTTTCTAGAATTAAAACAACCTAGTTTATAGTGAAGTTTACAATAGTTAAATATATACATAG
CCTGTTAATTTCTCAGGTCTCCGATTTGCTGGGTAGCTTTTCTGTGTTTTATAAGTATCTTCAT
ATATCCCTAATATTGTTTACTATGCGTTTAAAAATTCTTTATCCACAGTACTACAAAATATGAT
CCAAAAAAACACAGTTGCCTATTGTTAAGTTAGTGGACAAGAGGGTAAATGAGATACTTTTAAC
CAAAGAACAGGTTGTTTTGAATATGCTGAGATGTGACAAGCCAGGAAAGGGAACACTGCCTGTC
CTGGGGCAGGGGTCTGGCCCTACCAGACCTGATACTTCAGAAACCCTTTTTAATTACCCACAAG
TAGATGGTCACATGACTTCTTGCCAAGTGCTTCAGGATTCTGGATGGTCTGTTGTTACCGTGTG
AAGGATTAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_021727769 ⟹ XP_021583444

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,148,960 (-)	NCBI
SpeTri2.0	NW_004936532	5,864,851 - 5,903,928 (-)	NCBI

Sequence:

show sequence

GATCTGCAAGCCTCAACACATTTGGAAACATTACTAACTTTTTCAGCTTTGAAAAGCCACTTTG
GAGATTTGTTAATGATACTGAGGACAAAAGAATGTTAGTTTATAAGTCAGAAGATATCAAGAAT
GTTTCACGTTTACAGTCTCCAAAAGTATGTGGTTATTTAAAAGTGGATAATGAAGAGTTGCTTC
CAAAAGGACTGGTAGACAGAGAGCCACCTGAAGAGTTTGTTCATCGAGTGAAGAGAAGAGCTGA
TCCTAATCCCATGAAGAACACTTGTAAATTATTGGTGGTAGCAGATCATCGCTTTTATAAATAC
ATGGGCAGAGGGGAAGAAAGCACCACTACCAATTACTTAATAGAGCTAATTGACAGAGTTGATG
ACATCTATCGGAACACTTCGTGGGATAATGCGGGTTTTAAAGGTTATGGAATACAGATAGAGCA
GATTCGCATTCTCAAGTCGCCACAAGAGGTAAAACCTGGTGAAAGGCACTACAACATGGCAAAA
AGTTACCCAAATGAAGACAAGGATGCTTGGGATGTGAAGATGTTGCTAGAGCAATTTAGCTTTG
ATATAGCTGAAGAAGCATCTAAAGTCTGCCTGGCACACCTTTTCACATATCAGGATTTCGATAT
GGGAACTCTTGGATTAGCTTATGTTGGTTCTCCCAGAGCAAACAGTCATGGAGGTGTTTGTCCA
AAAGCTTATTATAGTCCAGTTGGGAAGAAAAATATCTACTTGAATAGTGGTTTGACCAGCACAA
AAAATTATGGTAAAACCATCCTTACAAAGGAAGCTGATCTTGTTACGACTCATGAATTGGGACA
CAATTTTGGAGCAGAACATGATCCTGATGGTCTAGCAGAATGTGCTCCGAATGAGGACCAGGGA
GGAAAGTATGTTATGTATCCTATAGCTGTGAGTGGTGACCATGAGAACAATAAGATGTTTTCAA
ACTGCAGTAAGCAGTCCATCTATAAGACTATTGAAAGTAAGGCCCAGGAGTGTTTTAAGGAGCG
GAGCAACAAGGTGTGTGGGAACTCCAGGGTGGATGAAGGAGAAGAATGTGACCCCGGCATCATG
TACCTGAATAATGACACCTGCTGCAATAGCGACTGCACACTGAAACCAGGTGTACAGTGCAGTG
ACAGGAACAGTCCTTGCTGTAAGAACTGTCAGTTTGAGACTGCCCAGAAGAAGTGCCAGGAGGC
TATTAATGCTACCTGCAAAGGCGTGTCTTACTGCACAGGGAACAGCAGTGAGTGTCCACCACCA
GGAAATGCTGAAGATGATACAGTTTGCTTGGACCTTGGCAAGTGTAAGGATGGGAAGTGCATCC
CCTTCTGTGAGAGGGAGCAGCAGCTGGAGCCCTGTGCGTGCAACGAAACTGACAACTCATGCAA
GGTGTGCTGTAGAGACCGTTCTGGCCGGTGTGTACCCTATGTCGACGCTGAGCAAAAGAACCTA
TTTTTAAGGAAAGGGAAGCCCTGTACAGTAGGGTTTTGTGACATGAATGGCAAATGCGAGAAAC
GAGTACAGGATGTAATAGAGAGATTTTGGGATTTCATTGACCAGTTGAGCATCAATACTTTTGG
GAAGTTTTTAGCAGACAACATCGTAGGATCTGTCCTGGTTTTCTCCTTGATATTTTGGATTCCT
TTCAGTATTCTTGTTCATTGTGTGGATAAGAAATTGGATAAGCAATATGAATCGCTGTCTCTGT
TTAACCCCAGTAATGTTGAGATGTTAAGCAGCATGGATTCGGCCTCAGTTCGAATTATCAAGCC
CTTTCCTGCACCCCAGACTCCAGGCCGCCTGCAGCCCCTACAGCCTACCCCTGTGATGCCACCA
GTGTCTGCTGCTCCAAAACTGGACCACCAGAGAATGGACACCATCCAAGAAGACCCCAGCACAG
ACTCACATATGGATGAGGATGGCTTTGAAAAGGACCCCTTCCCTAACAGTGGCACAGCTGCCAA
GTCCTTTGAGGATCTCACGGACCATCCAGTCACCAGAAGTGAAAAGGCTGCTTCCTTTAAACTG
CAGCGTCAGAATCGTGTGGACAGCAAAGAAACTGAGTGCTAGTGAGGGTCATGTCCTAAGTGAT
TTTGACTTACACGTGCAAATATTTTTATAAATTTGGCCTAGAAGCATGGCATATATCTTGTGAA
GAACTGGGAGGAATAAGGAAATTACTCAACAGCAAATGCTGGCCATGTGTTTGAGCTTCCTTCA
CATAAGCAGTGCTGTCTAGTTAAGACCCTCTTCCTTTGAAAAGGTCAGGTGAATCTGGCTTATT
TTCAGACTTTCAGGTTTTAGTGTTTTTGAGTTTCAAAACAGCCTTTGACCTGGTGGTGCAAAAG
CAGAAAATACAGCTGGGTTAGATTACTGTAAATTAACCTTTATGTTGATAACAGCACTGATCTT
TTATATACTGTAATGACCCTATGAGGCACTTAGCAGTTATTTGAGAGGACAACTGGAACAATTT
TTTTTTTTCAAGTAAAGGCAAAGGAATGAGATAATCTATTATTGCCAAAACGTGGGTGTTTCTA
GGTATTACCCAGATCTTTTCACAGCAGGGAGAAAGCTACATCTAAACTTACAAATAATTTGGGT
GAATAGGGTTTTTTTTCCTAAGGCTAGTGCTTTCTAGAATTAAAACAACCTAGTTTATAGTGAA
GTTTACAATAGTTAAATATATACATAGCCTGTTAATTTCTCAGGTCTCCGATTTGCTGGGTAGC
TTTTCTGTGTTTTATAAGTATCTTCATATATCCCTAATATTGTTTACTATGCGTTTAAAAATTC
TTTATCCACAGTACTACAAAATATGATCCAAAAAAACACAGTTGCCTATTGTTAAGTTAGTGGA
CAAGAGGGTAAATGAGATACTTTTAACCAAAGAACAGGTTGTTTTGAATATGCTGAGATGTGAC
AAGCCAGGAAAGGGAACACTGCCTGTCCTGGGGCAGGGGTCTGGCCCTACCAGACCTGATACTT
CAGAAACCCTTTTTAATTACCCACAAGTAGATGGTCACATGACTTCTTGCCAAGTGCTTCAGGA
TTCTGGATGGTCTGTTGTTACCGTGTGAAGGATTAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_021727770 ⟹ XP_021583445

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,148,959 (-)	NCBI
SpeTri2.0	NW_004936532	5,864,851 - 5,904,005 (-)	NCBI

Sequence:

show sequence

AGAAGCTTGATTCTTTGCTCTCAGACTACGATATCCTCTCTCTTGCCAATATCCAGCAGCACTC
CATAAGGAAAAGGGATCTGCAAGCCTCAACACATTTGGAAACATTACTAACTTTTTCAGCTTTG
AAAAGGCATTTTAAATTGTACTTGACATCAAGTACCGAACGCTTTTCACAAAATTTCAAAGTTG
TGGTGGTGGATGGTGAAGATGAAAGCGAGTACACTGTAAAATGGCAAGACTTCTTCAGTGGACA
TGTGGTTGGTGAGCCTAACTCTAGAGTCCTAGCCCATATAGGAGATGATGATGTTATAATAAGA
ATCAACACAGATGGGGCAGAATATAACATAGAGCCACTTTGGAGATTTGTTAATGATACTGAGG
ACAAAAGAATGTTAGTTTATAAGTCAGAAGATATCAAGAATGTTTCACGTTTACAGTCTCCAAA
AGTATGTGGTTATTTAAAAGTGGATAATGAAGAGTTGCTTCCAAAAGGACTGGTAGACAGAGAG
CCACCTGAAGTGCATACAAATTCATATTAGAGTTTGTTCATCGAGTGAAGAGAAGAGCTGATCC
TAATCCCATGAAGAACACTTGTAAATTATTGGTGGTAGCAGATCATCGCTTTTATAAATACATG
GGCAGAGGGGAAGAAAGCACCACTACCAATTACTTAATAGAGCTAATTGACAGAGTTGATGACA
TCTATCGGAACACTTCGTGGGATAATGCGGGTTTTAAAGGTTATGGAATACAGATAGAGCAGAT
TCGCATTCTCAAGTCGCCACAAGAGGTAAAACCTGGTGAAAGGCACTACAACATGGCAAAAAGT
TACCCAAATGAAGACAAGGATGCTTGGGATGTGAAGATGTTGCTAGAGCAATTTAGCTTTGATA
TAGCTGAAGAAGCATCTAAAGTCTGCCTGGCACACCTTTTCACATATCAGGATTTCGATATGGG
AACTCTTGGATTAGCTTATGTTGGTTCTCCCAGAGCAAACAGTCATGGAGGTGTTTGTCCAAAA
GCTTATTATAGTCCAGTTGGGAAGAAAAATATCTACTTGAATAGTGGTTTGACCAGCACAAAAA
ATTATGGTAAAACCATCCTTACAAAGGAAGCTGATCTTGTTACGACTCATGAATTGGGACACAA
TTTTGGAGCAGAACATGATCCTGATGGTCTAGCAGAATGTGCTCCGAATGAGGACCAGGGAGGA
AAGTATGTTATGTATCCTATAGCTGTGAGTGGTGACCATGAGAACAATAAGATGTTTTCAAACT
GCAGTAAGCAGTCCATCTATAAGACTATTGAAAGTAAGGCCCAGGAGTGTTTTAAGGAGCGGAG
CAACAAGGTGTGTGGGAACTCCAGGGTGGATGAAGGAGAAGAATGTGACCCCGGCATCATGTAC
CTGAATAATGACACCTGCTGCAATAGCGACTGCACACTGAAACCAGGTGTACAGTGCAGTGACA
GGAACAGTCCTTGCTGTAAGAACTGTCAGTTTGAGACTGCCCAGAAGAAGTGCCAGGAGGCTAT
TAATGCTACCTGCAAAGGCGTGTCTTACTGCACAGGGAACAGCAGTGAGTGTCCACCACCAGGA
AATGCTGAAGATGATACAGTTTGCTTGGACCTTGGCAAGTGTAAGGATGGGAAGTGCATCCCCT
TCTGTGAGAGGGAGCAGCAGCTGGAGCCCTGTGCGTGCAACGAAACTGACAACTCATGCAAGGT
GTGCTGTAGAGACCGTTCTGGCCGGTGTGTACCCTATGTCGACGCTGAGCAAAAGAACCTATTT
TTAAGGAAAGGGAAGCCCTGTACAGTAGGGTTTTGTGACATGAATGGCAAATGCGAGAAACGAG
TACAGGATGTAATAGAGAGATTTTGGGATTTCATTGACCAGTTGAGCATCAATACTTTTGGGAA
GTTTTTAGCAGACAACATCGTAGGATCTGTCCTGGTTTTCTCCTTGATATTTTGGATTCCTTTC
AGTATTCTTGTTCATTGTGTGGATAAGAAATTGGATAAGCAATATGAATCGCTGTCTCTGTTTA
ACCCCAGTAATGTTGAGATGTTAAGCAGCATGGATTCGGCCTCAGTTCGAATTATCAAGCCCTT
TCCTGCACCCCAGACTCCAGGCCGCCTGCAGCCCCTACAGCCTACCCCTGTGATGCCACCAGTG
TCTGCTGCTCCAAAACTGGACCACCAGAGAATGGACACCATCCAAGAAGACCCCAGCACAGACT
CACATATGGATGAGGATGGCTTTGAAAAGGACCCCTTCCCTAACAGTGGCACAGCTGCCAAGTC
CTTTGAGGATCTCACGGACCATCCAGTCACCAGAAGTGAAAAGGCTGCTTCCTTTAAACTGCAG
CGTCAGAATCGTGTGGACAGCAAAGAAACTGAGTGCTAGTGAGGGTCATGTCCTAAGTGATTTT
GACTTACACGTGCAAATATTTTTATAAATTTGGCCTAGAAGCATGGCATATATCTTGTGAAGAA
CTGGGAGGAATAAGGAAATTACTCAACAGCAAATGCTGGCCATGTGTTTGAGCTTCCTTCACAT
AAGCAGTGCTGTCTAGTTAAGACCCTCTTCCTTTGAAAAGGTCAGGTGAATCTGGCTTATTTTC
AGACTTTCAGGTTTTAGTGTTTTTGAGTTTCAAAACAGCCTTTGACCTGGTGGTGCAAAAGCAG
AAAATACAGCTGGGTTAGATTACTGTAAATTAACCTTTATGTTGATAACAGCACTGATCTTTTA
TATACTGTAATGACCCTATGAGGCACTTAGCAGTTATTTGAGAGGACAACTGGAACAATTTTTT
TTTTTCAAGTAAAGGCAAAGGAATGAGATAATCTATTATTGCCAAAACGTGGGTGTTTCTAGGT
ATTACCCAGATCTTTTCACAGCAGGGAGAAAGCTACATCTAAACTTACAAATAATTTGGGTGAA
TAGGGTTTTTTTTCCTAAGGCTAGTGCTTTCTAGAATTAAAACAACCTAGTTTATAGTGAAGTT
TACAATAGTTAAATATATACATAGCCTGTTAATTTCTCAGGTCTCCGATTTGCTGGGTAGCTTT
TCTGTGTTTTATAAGTATCTTCATATATCCCTAATATTGTTTACTATGCGTTTAAAAATTCTTT
ATCCACAGTACTACAAAATATGATCCAAAAAAACACAGTTGCCTATTGTTAAGTTAGTGGACAA
GAGGGTAAATGAGATACTTTTAACCAAAGAACAGGTTGTTTTGAATATGCTGAGATGTGACAAG
CCAGGAAAGGGAACACTGCCTGTCCTGGGGCAGGGGTCTGGCCCTACCAGACCTGATACTTCAG
AAACCCTTTTTAATTACCCACAAGTAGATGGTCACATGACTTCTTGCCAAGTGCTTCAGGATTC
TGGATGGTCTGTTGTTACCGTGTGAAGGATTAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_040271255 ⟹ XP_040127189

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,134,786 (-)	NCBI

RefSeq Acc Id:

XM_040271256 ⟹ XP_040127190

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,131,298 (-)	NCBI

RefSeq Acc Id:

XM_040271257 ⟹ XP_040127191

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,134,786 (-)	NCBI

RefSeq Acc Id:

XM_040271258 ⟹ XP_040127192

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	51,109,736 - 51,127,422 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_021583443	(Get FASTA)	NCBI Sequence Viewer
	XP_021583444	(Get FASTA)	NCBI Sequence Viewer
	XP_021583445	(Get FASTA)	NCBI Sequence Viewer
	XP_040127189	(Get FASTA)	NCBI Sequence Viewer
	XP_040127190	(Get FASTA)	NCBI Sequence Viewer
	XP_040127191	(Get FASTA)	NCBI Sequence Viewer
	XP_040127192	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000004050.3
	ENSSTOP00000024566.1
GenBank Protein	KAG3267572	(Get FASTA)	NCBI Sequence Viewer
	KAG3267573	(Get FASTA)	NCBI Sequence Viewer
	KAG3267574	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021583445 ⟸ XM_021727770

- Peptide Label:

isoform X3

- Sequence:

show sequence

MKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRI
LKSPQEVKPGERHYNMAKSYPNEDKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTL
GLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFG
AEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFKERSNK
VCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLEPCACNETDNSCKVCC
RDRSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFL
ADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFNPSNVEMLSSMDSASVRIIKPFPA
PQTPGRLQPLQPTPVMPPVSAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSGTAAKSFE
DLTDHPVTRSEKAASFKLQRQNRVDSKETEC

hide sequence

RefSeq Acc Id:	XP_021583444 ⟸ XM_021727769
- Peptide Label:	isoform X2
- UniProtKB:	A0A287CTF1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEEFVHRVKRRADPNPMKNTCKL LVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEV KPGERHYNMAKSYPNEDKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGS PRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDG LAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFKERSNKVCGNSRV DEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSY CTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLEPCACNETDNSCKVCCRDRSGRC VPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGS VLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFNPSNVEMLSSMDSASVRIIKPFPAPQTPGRL QPLQPTPVMPPVSAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSGTAAKSFEDLTDHPV TRSEKAASFKLQRQNRVDSKETEC hide sequence

RefSeq Acc Id:	XP_021583443 ⟸ XM_021727768
- Peptide Label:	isoform X1
- UniProtKB:	A0A287CTF1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWLPLWRFVNDTEDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEEFVHR VKRRADPNPMKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGY GIQIEQIRILKSPQEVKPGERHYNMAKSYPNEDKDAWDVKMLLEQFSFDIAEEASKVCLAHLFT YQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVT THELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQ ECFKERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQ KKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLEPCACNE TDNSCKVCCRDRSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQL SINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFNPSNVEMLSSMDSAS VRIIKPFPAPQTPGRLQPLQPTPVMPPVSAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPN SGTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC hide sequence

RefSeq Acc Id:	XP_040127189 ⟸ XM_040271255
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_040127191 ⟸ XM_040271257
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_040127190 ⟸ XM_040271256
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_040127192 ⟸ XM_040271258
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSSTOP00000024566 ⟸ ENSSTOT00000039422

RefSeq Acc Id:

ENSSTOP00000004050 ⟸ ENSSTOT00000004513

Protein Domains

Disintegrin Peptidase M12B

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004510	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004513.3	UniProtKB/TrEMBL
	ENSSTOT00000039422.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.390.10	UniProtKB/TrEMBL
	4.10.70.10	UniProtKB/TrEMBL
	4.10.70.30	UniProtKB/TrEMBL
InterPro	ADAM10_ADAM17	UniProtKB/TrEMBL
	ADAM17_MPD	UniProtKB/TrEMBL
	Disintegrin_dom	UniProtKB/TrEMBL
	Disintegrin_dom_sf	UniProtKB/TrEMBL
	MetalloPept_cat_dom_sf	UniProtKB/TrEMBL
	Peptidase_M12B	UniProtKB/TrEMBL
NCBI Gene	Adam17	ENTREZGENE
PANTHER	ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER	UniProtKB/TrEMBL
	DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17	UniProtKB/TrEMBL
Pfam	ADAM17_MPD	UniProtKB/TrEMBL
	Disintegrin	UniProtKB/TrEMBL
	Reprolysin_2	UniProtKB/TrEMBL
PROSITE	ADAM_MEPRO	UniProtKB/TrEMBL
	DISINTEGRIN_2	UniProtKB/TrEMBL
SMART	DISIN	UniProtKB/TrEMBL
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
	SSF57552	UniProtKB/TrEMBL
UniProt	A0A287CTF1	ENTREZGENE, UniProtKB/TrEMBL
	I3M4E0_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)